alanine and midazolam

alanine has been researched along with midazolam in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kempski, OS; Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF1
Clemens, PL; Dhar, A; Kollia, G; Lathers, D; Masson, E; Syed, S; Walters, I1
Annes, WF; Ayan-Oshodi, MA; Brown, T; de la Peña, A; Friedrich, S; Hall, SD; Lowe, SL; Willis, BA; Wise, SD; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1

Trials

3 trial(s) available for alanine and midazolam

ArticleYear
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients.
    Psychopharmacology, 1999, Volume: 141, Issue:1

    Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Humans; Hypnotics and Sedatives; Lactates; Midazolam; Middle Aged; Serine; Thiopental

1999
Lack of effect of brivanib on the pharmacokinetics of midazolam, a CYP3A4 substrate, administered intravenously and orally in healthy participants.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:6

    Topics: Administration, Oral; Adult; Alanine; Antineoplastic Agents; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Fibroblast Growth Factors; Half-Life; Humans; Injections, Intravenous; Intestines; Liver; Male; Metabolic Detoxication, Phase I; Midazolam; Middle Aged; Patient Dropouts; Prodrugs; Receptors, Vascular Endothelial Growth Factor; Triazines

2012
The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:10

    Topics: Administration, Oral; Adult; Aged; Alanine; Amyloid Precursor Protein Secretases; Area Under Curve; Azepines; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Half-Life; Hepatocytes; Humans; Hydroxylation; Ketoconazole; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Models, Biological; Nifedipine; Testosterone; Young Adult

2012

Other Studies

1 other study(ies) available for alanine and midazolam

ArticleYear
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009