alanine has been researched along with metformin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Alberti, KG; Hinks, L; Lloyd, B; Nattrass, M; Todd, PG | 1 |
| Assan, R; Bismuth, C; Ganeval, D; George, J; Girard, JR; Heuclin, C | 1 |
| Freund, H; Frick, A; Imler, M; Marbach, J; Schlienger, JL | 1 |
| Alberti, KG; Hinks, L; Nattrass, M; Smythe, P; Todd, PG | 1 |
| Alberti, KG; Betteridge, DJ; Cudworth, AG; De Silva, SR; Shawe, JE | 1 |
| Benzi, L; Brunetti, P; Cecchetti, P; Di Carlo, A; Di Cianni, G; Giannarelli, R; Gregorio, F; Marchetti, P; Navalesi, R; Villani, G | 1 |
| Bailey, CJ; Wollen, N | 1 |
| Campagnolo, M; Ceolotto, G; Da Tos, V; Del Prato, S; Dorella, M; Felice, M; Giusto, M; Palatini, P; Rossi, G; Semplicini, A | 1 |
| Hamada, Y; Hara, T; Hotta, N; Koh, N; Komori, T; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Takeuchi, N | 1 |
| Cherrington, AD; Chu, CA; Knauf, M; Muscato, N; Neal, DW; Wiernsperger, N | 1 |
| Andrikopoulos, S; Filippis, C; Khan, D; Proietto, J; Song, S; Thorburn, AW | 1 |
| Bilodeau-Goeseels, S; Guillemette, C; Richard, FJ; Sasseville, M | 1 |
| Altshuler, D; Delahanty, L; Florez, JC; Franks, PW; Hanson, RL; Jablonski, KA; Kahn, SE; Knowler, WC | 1 |
| Fromm, MF; König, J; Solbach, TF; Zolk, O | 1 |
| Fujiwara, T; Hagisawa, Y; Kanda, S; Nakashima, R; Ogawa, J; Okuno, A; Takahashi, K; Tanaka, J; Yoshida, T | 1 |
| Baptista, T; Carrizo, E; Connell, L; Fernández, E | 1 |
| Alves, MG; Correia, S; Martins, AD; Moreira, PI; Oliveira, PF; Socorro, S; Vaz, CV | 1 |
3 trial(s) available for alanine and metformin
| Article | Year |
|---|---|
Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment.
Topics: Alanine; Blood Glucose; Cholesterol; Circadian Rhythm; Clofibrate; Diabetes Mellitus; Drug Synergism; Fibrinogen; Glycerol; Humans; Hydroxybutyrates; Lactates; Lipoproteins; Metformin; Triglycerides | 1979 |
Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin-resistant hypertensive patients with normal glucose tolerance.
Topics: Adult; Aged; Alanine; Aldosterone; Blood Glucose; Blood Pressure; Body Weight; Cross-Over Studies; Double-Blind Method; Epinephrine; Erythrocyte Membrane; Female; Glucose; Glucose Clamp Technique; Glycerol; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Kidney; Lactates; Male; Metformin; Middle Aged; Norepinephrine; Placebos; Renin; Sodium | 1996 |
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.
Topics: Adult; Alanine; Amino Acid Substitution; Body Composition; Chromans; Diabetes Mellitus, Type 2; Dietary Fats; Eating; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Life Style; Male; Metformin; Middle Aged; Obesity; Placebos; PPAR gamma; Proline; Thiazolidinediones; Troglitazone | 2007 |
15 other study(ies) available for alanine and metformin
| Article | Year |
|---|---|
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics.
Topics: Aged; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Female; Gluconeogenesis; Glyburide; Humans; Insulin; Ketone Bodies; Lactates; Lipids; Male; Metformin; Middle Aged; Phenformin; Pyruvates | 1977 |
Metformin-induced lactic acidosis in the presence of acute renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Alanine; Blood Glucose; Creatinine; Diabetic Ketoacidosis; Female; Humans; Insulin; Ketone Bodies; Lactates; Male; Metformin; Middle Aged; Pyruvates | 1977 |
Effects of biguanides on the intermediate metabolism of glucose in normal and portal-strictured rats.
Topics: Alanine; Ammonia; Animals; Blood Glucose; Constriction; Glutamine; Lactates; Liver Circulation; Male; Metformin; Phenformin; Portal Vein; Pyruvates; Rats; Urea | 1979 |
Metabolic effects of combined sulphonylurea and metformin therapy in maturity-onset diabetice.
Topics: Adult; Aged; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Female; Humans; Insulin; Ketone Bodies; Lactates; Male; Metformin; Middle Aged; Pyruvates; Sulfonylurea Compounds | 1979 |
Diurnal pattern of plasma metformin concentrations and its relation to metabolic effects in type 2 (non-insulin-dependent) diabetic patients.
Topics: Alanine; Blood Glucose; Butyrates; Butyric Acid; Circadian Rhythm; Diabetes Mellitus, Type 2; Glycerol; Humans; Lactates; Lactic Acid; Metformin; Pyruvates; Pyruvic Acid | 1990 |
Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.
Topics: Adenosine Triphosphate; Alanine; Animals; Drug Synergism; Gluconeogenesis; Insulin; Liver; Male; Metformin; NAD; Rats; Rats, Inbred Strains | 1988 |
Increased alanine uptake and lipid synthesis from alanine in isolated hepatocytes of Wistar-Kyoto fatty rats: an inhibitory effect of biguanides.
Topics: Aging; Alanine; Animals; Body Weight; Buformin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucagon; Hypoglycemic Agents; Lipids; Liver; Male; Metformin; Rats; Rats, Inbred WKY | 1997 |
The acute effect of metformin on glucose production in the conscious dog is primarily attributable to inhibition of glycogenolysis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Arteries; Dogs; Fatty Acids, Nonesterified; Female; Gluconeogenesis; Glucose; Glycerol; Glycogen; Hypoglycemic Agents; Kinetics; Lactic Acid; Liver; Male; Metformin; Plasma; Time Factors | 2000 |
Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.
Topics: Administration, Oral; Alanine; Animals; Blood Glucose; Body Weight; Dietary Fats; Fatty Acids, Nonesterified; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Glycogen; Hypoglycemic Agents; Insulin; Liver; Male; Metformin; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar | 2001 |
Effects of adenosine monophosphate-activated kinase activators on bovine oocyte nuclear maturation in vitro.
Topics: Alanine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Antibiotics, Antineoplastic; Cattle; Cell Nucleus; Colforsin; Cyclic AMP; Enzyme Activation; Female; Hypoglycemic Agents; Meiosis; Metformin; Multienzyme Complexes; Mycophenolic Acid; Oocytes; Protein Serine-Threonine Kinases; Protein Subunits; Ribonucleotides | 2007 |
Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Topics: Alanine; Amino Acid Substitution; Biological Transport; Cell Line; Genetic Variation; Humans; Kidney; Metabolic Clearance Rate; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 1; Protein Conformation; Protein Isoforms; Serine; Subcellular Fractions | 2009 |
Metformin primarily decreases plasma glucose not by gluconeogenesis suppression but by activating glucose utilization in a non-obese type 2 diabetes Goto-Kakizaki rats.
Topics: Alanine; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Hepatocytes; Hypoglycemic Agents; Inhibitory Concentration 50; Insulin; Lactic Acid; Male; Metformin; Organophosphonates; Organophosphorus Compounds; Radioisotope Dilution Technique; Rats; Rats, Mutant Strains; Rats, Wistar | 2009 |
Pro12Ala polymorphism of the PPAR-γ2 gene, metabolic syndrome and response to metformin in clozapine-treated patients.
Topics: Adult; Aged; Alanine; Antipsychotic Agents; Blood Glucose; Clozapine; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metabolic Diseases; Metformin; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2012 |
Metformin and male reproduction: effects on Sertoli cell metabolism.
Topics: Alanine; Animals; Cells, Cultured; Glucose Transporter Type 1; Glucose Transporter Type 3; Hypoglycemic Agents; L-Lactate Dehydrogenase; Lactic Acid; Male; Metformin; Monocarboxylic Acid Transporters; Muscle Proteins; Phosphofructokinase-1; Rats; Rats, Wistar; Reproduction; RNA, Messenger; Sertoli Cells | 2014 |