alanine has been researched along with lanthionine in 187 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (13.90) | 18.7374 |
| 1990's | 25 (13.37) | 18.2507 |
| 2000's | 46 (24.60) | 29.6817 |
| 2010's | 74 (39.57) | 24.3611 |
| 2020's | 16 (8.56) | 2.80 |
| Authors | Studies |
|---|---|
| Klostermeyer, H; Watanabe, K | 1 |
| Endresen, C; Hofstad, T; Jensen, HB; Vasstrand, EN | 1 |
| Feeney, RE; Nashef, AS; Walsh, RG | 1 |
| De Bree, PK; Kamerling, JP; Wadman, SK | 1 |
| Fiedler, HP; Hörner, T; Jung, G; Kellner, R; Ungermann, V; Utz, R; Zähner, H | 1 |
| Fredenhagen, A; Hänni, E; Märki, F; van Oostrum, J | 1 |
| Chang, JY; Knecht, R | 1 |
| Fredriksen, A; Jensen, HB; Vasstrand, EN | 1 |
| Fujita, H; Fukase, K; Goodman, M; Kitazawa, M; Mierke, DF; Palmer, DE; Pattaroni, C; Shiba, T; Wakamiya, T | 1 |
| Cavallini, D; Costa, M; Fontana, M; Pecci, I; Pensa, B | 1 |
| Entian, KD; Götz, F; Hörner, T; Jung, G; Kellner, R; Schnell, N; Zähner, H | 1 |
| Bessems, GJ; Hoenders, HJ; Rennen, HJ | 1 |
| Cavallini, D; Federici, G; Nardini, M; Ricci, G | 1 |
| Kunert, J | 1 |
| Brandis, H; Cramer, WA; Grossgarten, M; Sahl, HG; Widger, WR | 1 |
| Baker, DH; Finley, JW; Robbins, KR | 1 |
| Hofstad, T; Jensen, HB; Miron, T; Vasstrand, EN | 1 |
| Achilli, M; Cavallini, D; Federici, G; Lucente, G; Ricci, G | 1 |
| Jack, RW; Sahl, HG | 1 |
| Jung, G; Metzger, JW; Zimmermann, N | 1 |
| Blanot, D; Mengin-Lecreulx, D; van Heijenoort, J | 1 |
| Carne, A; Jack, RW; Jung, G; Metzger, J; Sahl, HG; Stefanović, S; Tagg, J | 1 |
| Cohen, GN; Johnson, EJ; Marlière, P; Mengin-Lecreulx, D; Pochet, S; Richaud, C | 1 |
| Benz, R; Jack, R; Sahl, HG; Tagg, J | 1 |
| Ronson, CW; Ross, KF; Tagg, JR | 1 |
| Bierbaum, G; Sahl, HG | 1 |
| Mollet, B; Pittet, AC; Pridmore, D; Rekhif, N; Suri, B | 1 |
| Gasson, MJ | 1 |
| Bierbaum, G; Heidrich, C; Jack, R; Sahl, HG | 1 |
| Nes, IF; Tagg, JR | 1 |
| Israil, AM; Jack, RW; Jung, G; Sahl, HG | 1 |
| Bierbaum, G; Brötz, H; Jack, R; Kluczny, C; Molitor, E; Sahl, HG | 1 |
| Coy, DH; Goodman, M; Kim, HS; Liapakis, G; Mattern, RH; Medzihradszky, KF; Melacini, G; Osapay, G; Prokai, L; Reisine, T; Wang, SH; Zhu, Q | 1 |
| Goodman, M; Melacini, G; Osapay, G; Zhu, Q | 1 |
| Ageta, T; Duprè, S; Fontana, M; Kodama, H; Sugahara, K; Yu, S; Zhang, J | 1 |
| Casadesús, J; D'Ari, R | 1 |
| Groeger, S; Jarosinski, MA; Liu, CF; Mayer, JP; Zhang, J | 1 |
| Friedman, M | 1 |
| Kärcher, J; Lubini, P; Pohl, E; Schneider, TR; Sheldrick, GM | 1 |
| Allen, C; Bradley, M; Burrage, S; Cardno, M; Essex, JW; Raynham, T; Swali, V; Williams, G | 1 |
| Goodman, M; Jiang, X; Li, H | 1 |
| Hill, C; McAuliffe, O; Ross, RP | 1 |
| Goodman, M; Rew, Y; Zapf, C | 1 |
| Cassel, JA; Chung, NN; DeHaven, RN; Goodman, M; Malkmus, S; Rew, Y; Schiller, PW; Svensson, C; Taulane, JP; Yaksh, TL | 1 |
| Helin, J; Koponen, O; Qiao, M; Saris, PEJ; Tolonen, M; Wahlström, G | 1 |
| Goodman, M; Malkmus, S; Rew, Y; Schiller, PW; Svensson, CI; Taulane, JP; Yaksh, TL | 1 |
| Goodman, M; Smith, ND | 1 |
| SCHOBERL, A; WAGNER, A | 1 |
| MORGAN, JF; MORTON, HJ | 1 |
| MIJAL, CF; SULLIVAN, MX | 1 |
| EARLAND, C; RAVEN, DJ | 1 |
| GOLSCH, E; ZAHN, H | 1 |
| CREWTHER, WG; DOWLING, LM | 1 |
| PRESCOTT, JM | 1 |
| Bregant, S; Bulic-Subanovic, N; Chubb, NA; Driscoll, PC; Elliott, SL; Gaffney, PR; Groussier, MF; Harris, R; Mohd Mustapa, MF; Mould, J; Schultz, D; Tabor, AB | 1 |
| Chubb, NA; Driscoll, PC; Esposito, D; Harris, R; Mohd Mustapa, MF; Mould, J; Schultz, D; Tabor, AB | 1 |
| Averin, O; Gieselman, MD; van der Donk, WA; Zhou, H; Zhu, Y | 1 |
| IRION, W | 1 |
| FOLK, JE; SULLIVAN, MX | 1 |
| Carpenter, MR; Cotter, PD; Hill, C; Martin, NI; Ross, RP; Sprules, T; Vederas, JC | 1 |
| Hill, JM; Hu, F; LeGrand, RD; Linetsky, M | 1 |
| Cotter, PD; Hill, C; Ross, RP | 1 |
| Consaul, SA; Crick, DC; Mahapatra, S; Pavelka, MS; Wright, LF | 1 |
| Bregant, S; Tabor, AB | 1 |
| de Boef, E; Driessen, AJ; Kuipers, A; Kuipers, OP; Leenhouts, KJ; Moll, GN; Rink, R | 1 |
| LeGrand, RD; Linetsky, M | 1 |
| Aso, Y; Harada, Y; Nagao, J; Nakayama, J; Shioya, K; Sonomoto, K; Zendo, T | 1 |
| Durrant, MC; Kodani, S; Lodato, MA; Picart, F; Willey, JM | 1 |
| Kodani, S; Nodwell, JR; Willems, A; Willey, JM | 1 |
| Brock, R; Jung, G; Seyberth, T; Voss, S; Wiesmüller, KH | 1 |
| Baker, DH | 1 |
| Breukink, E | 1 |
| Avenoza, A; Busto, JH; Jiménez-Osés, G; Peregrina, JM | 1 |
| Fujimoto, Y; Fukase, K; Kawasaki, A; Kusumoto, S; Takada, H; Uehara, A | 1 |
| Chatterjee, C; Cooper, L; Patton, GC; Paul, M; van der Donk, WA | 1 |
| Ghalit, N; Hilbers, HW; Kemmink, J; Liskamp, RM; Rijkers, DT; Versluis, C | 1 |
| He, H; Lipowska, M; Marzilli, LG; Taylor, AT; Xu, X | 1 |
| Cobb, SL; Vederas, JC | 1 |
| Höcker, H; Popescu, C | 1 |
| Liu, H; Pattabiraman, VR; Vederas, JC | 1 |
| Aso, H; Fujimoto, Y; Fukase, K; Kawasaki, A; Kitazawa, H; Saito, T; Shimazu, T; Takada, H; Tohno, M; Uehara, A | 1 |
| Bonev, B; Breukink, E; Carey, S; Chan, WC; Narbad, A; Parisot, J | 1 |
| Chatterjee, C; Cooper, LE; Patton, GC; Paul, M; van der Donk, WA | 1 |
| Fukao, M; Kohda, D; Nakayama, J; Obita, T; Sonomoto, K; Yoneyama, F; Zendo, T | 1 |
| CALDWELL, A; HORN, MJ; JONES, DB | 2 |
| Martin, NI | 1 |
| Håkansson, K; Kalli, A; Kastrantas, J; Orugunty, RS; Smith, L; Wilson-Stanford, S | 1 |
| Haugen, HS; Kristiansen, PE; Nissen-Meyer, J; Oppegård, C; Rogne, P | 1 |
| Balaram, P; Thakur, SS | 1 |
| Basler, DA; Cagney, JW; Carroll, JA; Chen, ZY; Egodage, K; Lipartito, C; Poruthoor, S; Schlittler, MR; Storrs, SB; Tou, JS; Violand, BN | 1 |
| Banerjee, R; Chiku, T; Padovani, D; Singh, S; Vitvitsky, V; Zhu, W | 1 |
| Cooper, LE; Li, B; van der Donk, WA | 1 |
| Banerjee, R; Chiku, T; Leslie, RA; Padovani, D; Singh, S | 1 |
| Khusainov, R; Kuipers, OP; Lubelski, J | 1 |
| Kuipers, A; Moll, GN; Rink, R | 1 |
| Draelos, ZD | 1 |
| MIDDLEBROOK, WR; PHILLIPS, H | 1 |
| Bibb, MJ; Claesen, J; Goto, Y; Li, B; Shi, Y; van der Donk, WA | 1 |
| Ito, S; Kamo, M; Kato, H; Kezuka, Y; Kunimatsu, K; Tamura, H; Yoshida, Y | 1 |
| Christov, A; Hensley, K; Venkova, K | 1 |
| Brijs, K; De Vleeschouwer, K; Delcour, JA; Hendrickx, ME; Lagrain, B; Rombouts, I | 1 |
| Cotter, PD; Hill, C; O'Connor, PM; Ross, RP; Suda, S; Westerbeek, A | 1 |
| Callery, PS; Cooper, AJ; Pinto, JT | 1 |
| Ajandouz, EH; Crost, EH; Fons, M; Geraert, PA; Puigserver, A; Villard, C | 1 |
| Inoue, T; Ito, A; Kitajima, Y; Shimizu, N; Shinohara, K; Takehara, K | 1 |
| Appleyard, AN; Mothia, B; Tabor, AB; Wadman, S | 1 |
| Brijs, K; Delcour, JA; Lagrain, B; Rombouts, I | 1 |
| Tabor, AB | 1 |
| Avenoza, A; Aydillo, C; Busto, JH; Jiménez-Osés, G; Peregrina, JM; Zurbano, MM | 1 |
| Krawczyk, B; Krawczyk, JM; Nachtigall, J; Pesic, A; Süssmuth, RD; Völler, GH | 1 |
| Tang, W; van der Donk, WA | 2 |
| van der Donk, WA; Wang, H | 1 |
| Ensle, P; Krawczyk, B; Süssmuth, RD; Völler, GH; Völler, J | 1 |
| Khawli, LA; Pastuskovas, CV; Stults, JT; Yin, S | 1 |
| Hirschberger, LL; Kožich, V; Krijt, J; Roman, HB; Stipanuk, MH; Valli, A | 1 |
| Castro Faria Neto, HC; Floyd, RA; Hensley, K; Towner, RA; Zimmerman, GA | 1 |
| van der Donk, WA; Yu, Y; Zhang, Q | 1 |
| Donadio, S; Gaspari, E; Iorio, M; Maffioli, SI; Monciardini, P; Sosio, M | 1 |
| Sareen, D; Singh, M | 1 |
| Sakamaki, R; Shimada, Y; Takahashi, N; Washio, J; Yamada, M | 1 |
| Mukherjee, S; van der Donk, WA | 1 |
| Blanot, D; Denoël, T; Gerards, T; Joris, B; Lemaire, C; Luxen, A; Zervosen, A | 1 |
| Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA | 1 |
| Breukink, E; Liskamp, RM; Peters, N; Quarles van Ufford, HL; Rijkers, DT; Slootweg, JC | 1 |
| Li, JL; Lohans, CT; Vederas, JC | 1 |
| van der Donk, WA; Wang, H; Yang, X; Zhang, Q | 1 |
| Chen, J; van der Donk, WA; Zeng, M | 1 |
| Blanot, D; Denoël, T; Hervé, M; Joris, B; Lemaire, C; Luxen, A; Zaragoza, G; Zervosen, A | 1 |
| Ha, T; Thibodeaux, CJ; van der Donk, WA | 1 |
| Denton, TT; Hensley, K | 1 |
| Altschuh, D; Chekkat, N; Estieu-Gionnet, K; Fournel, S; Gronemeyer, H; Guichard, G; Lechner, MC; Odaert, B; Pavet, V; Pulka-Ziach, K; Rohac, R; Smulski, CR; Zeder-Lutz, G | 1 |
| Jones, B; Kazlauskas, RJ | 1 |
| Houk, KN; Jiménez-Osés, G; Tang, W; van der Donk, WA | 1 |
| Ananias, HJ; Carlucci, G; de Jong, IJ; de Paula Faria, D; Dierckx, RA; Elsinga, PH; Helfrich, W; Kuipers, A; Moll, GN; Rink, R | 1 |
| Ding, W; Li, Y; Zhang, Q | 1 |
| Doroghazi, JR; van der Donk, WA; Walker, MC; Zhang, Q; Zhao, X | 1 |
| Nagao, J; Nakayama, J; Nishie, M; Noguchi, M; Shimafuji, C; Shioya, K; Sonomoto, K; Zendo, T | 1 |
| Iftime, D; Imhoff, JF; Jasyk, M; Kulik, A; Stegmann, E; Süssmuth, RD; Weber, T; Wohlleben, W | 1 |
| Brunati, C; Cruz, JC; Donadio, S; Gaspari, E; Iorio, M; Maffioli, SI; Monciardini, P; Simone, M; Sosio, M; Wellington, E | 1 |
| Carpentier, SC; Delcour, JA; Lambrecht, MA; Rombouts, I | 1 |
| Ješina, P; Kožich, V; Kraus, JP; Krijt, J; Majtán, T; Melenovská, P; Sokolová, J; Vozdek, R | 1 |
| Huo, L; van der Donk, WA | 1 |
| Amoresano, A; Cirillo, G; Di Nunzio, A; Fontanarosa, C; Ingrosso, D; Pane, F; Perna, AF; Pucci, P; Trepiccione, F; Vigorito, C; Zacchia, M | 1 |
| Chen, T; Garg, N; Goto, Y; van der Donk, WA | 1 |
| Tang, W; Thibodeaux, GN; van der Donk, WA | 1 |
| Atkins, WM; Bouldin, SD; Guttman, M; Outten, CE; Scian, M | 1 |
| Ingrosso, D; Perna, AF; Trepiccione, F; Zacchia, M | 1 |
| Chen, J; Dutta, D; He, C; Koh, TH; van der Donk, WA; Zeng, M | 1 |
| Cai, YD; Chen, L; Huang, T; Wang, S; Zhang, N; Zhang, YH | 1 |
| Becker, JW; Berta-Thompson, JW; Chisholm, SW; Cubillos-Ruiz, A; van der Donk, WA | 1 |
| Lagedroste, M; Schmitt, L; Smits, SHJ | 1 |
| Gregory, JF; Kent, J; Kožich, V; Kraus, JP; Krijt, J; Křížková, M; Majtan, T; Ralat, MA; Sokolová, J | 1 |
| Bhaumik, S; Biswal, HS; Dolle, AB; Gowd, KH; Jagadeesh, N; Prakash, S | 1 |
| Anishchenko, E; D'Aniello, S; Ingrosso, D; Perna, AF; Trepiccione, F; Vigorito, C; Zacchia, M | 1 |
| Denoël, T; Lemaire, C; Luxen, A | 1 |
| Bobeica, SC; van der Donk, WA | 1 |
| Greco, I; Lametsch, R; Mitra, B; Ruiz-Carrascal, J | 1 |
| De Luca, S; Digilio, G; Jiménez-Osés, G; Menchise, V; Peregrina, JM; Saviano, M; Tovillas, P; Verdoliva, V | 1 |
| Franklin, R; Kuipers, A; Moll, GN; Wagner, E | 1 |
| Deng, J; Held, M; Kuipers, OP; Montalbán-López, M; Panke, S; Peterhoff, D; Schmitt, S; Wagner, R | 1 |
| Bobeica, SC; Bothwell, IR; Hegemann, JD; van der Donk, WA; Walker, MC | 1 |
| Anishchenko, E; Capasso, R; Capolongo, G; Ingrosso, D; Lombari, P; Mele, L; Perna, AF; Trepiccione, F; Vigorito, C; Zacchia, M | 1 |
| Abbate, M; Benigni, A; Cassis, P; Cerullo, D; Corna, D; Locatelli, M; Remuzzi, G; Rottoli, D; Villa, S; Zoja, C | 1 |
| Mothersole, RG; Wolthers, KR | 1 |
| Acedo, JZ; An, L; Bothwell, IR; Frazier, C; Trouth, A; van der Donk, WA | 1 |
| De Luca, S; Digilio, G; Jiménez-Osés, G; Peregrina, JM; Tovillas, P; Verdoliva, V | 1 |
| Baindara, P; Korpole, S; Nayudu, N | 1 |
| Alessandri, C; Brandstetter, H; Gadermaier, G; Griessner, I; Huber, CG; Mari, A; Regl, C; Soh, WT; Stemeseder, T; Stock, LG; Stutz, H; Völker, T; Wildner, S | 1 |
| Chaudhary, S; Sareen, D; Singh, M | 1 |
| Handfield, M; Hillman, JD; Kirichenko, K; Park, JH | 1 |
| Bosma, T; Cebrián, R; Fu, Y; Kuipers, OP; Moll, GN; Rink, R; Zhao, X | 1 |
| Gornbein, JA; Koos, BJ | 1 |
| Halbert, ME; Kittrell, CG; Limbrick, EM; Scott, DH; Shah, SC | 1 |
| Bosma, T; de Vries, L; Kuipers, A; Moll, GN; Namsolleck, P; Rink, R | 1 |
| Mescheder, A; Moll, GN; Namsolleck, P; Richardson, A | 1 |
| Chen, J; Chooi, KP; Davis, BG; Galan, SRG; Garg, N; He, C; Hutchings, GJ; Jones, LH; Lai, KY; Liu, S; Mohammed, S; Nair, SK; Raj, R; Riedl, J; van der Donk, WA; Zeng, M; Zeng, Y; Zhou, TH | 1 |
| Aziz, S; Berscheid, A; Brötz-Oesterhelt, H; Gehringer, M; Gross, H; Kramer, M; Saad, H; Straetener, J | 1 |
| Arias-Orozco, P; Cebrián, R; Inklaar, M; Kuipers, OP; Lanooij, J | 1 |
| De Luca, S; Digilio, G; Saviano, M; Verdoliva, V | 1 |
| Fernandez-Lima, FA; Jeanne Dit Fouque, K; Jiménez-Osés, G; Le, T; Navo, CD; Santos-Fernandez, M; Sarksian, R; van der Donk, WA | 1 |
| Genilloud, O; Liang, H; Lopez, IJ; Sánchez-Hidalgo, M; van der Donk, WA | 1 |
| Kuipers, OP; Viel, JH | 1 |
| Nair, SK; Pei, ZF; Sarksian, R; van der Donk, WA; Zhu, L | 1 |
| Brinker, CJ; Denton, TT; Gonzalez Porras, MA; Gransee, HM; Mantilla, CB; Noureddine, A; Shen, D; Sieck, GC; Webb, KL | 1 |
23 review(s) available for alanine and lanthionine
| Article | Year |
|---|---|
Unique peptide modifications involved in the biosynthesis of lantibiotics.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Forecasting; Gene Expression Regulation, Bacterial; Genes, Bacterial; Models, Chemical; Molecular Sequence Data; Peptides; Protein Precursors; Protein Processing, Post-Translational; Sulfides | 1995 |
Lantibiotics--unusually modified bacteriocin-like peptides from gram-positive bacteria.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Gram-Positive Bacteria; Molecular Sequence Data; Peptides; Sulfides | 1993 |
Lantibiotics.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Infections; Genes, Bacterial; Gram-Positive Bacteria; Humans; Molecular Sequence Data; Peptides, Cyclic; Protein Processing, Post-Translational; Protein Sorting Signals; Protein Structure, Secondary; Sulfides | 1995 |
The genetics of lantibiotic biosynthesis.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; Chromosome Mapping; Chromosomes, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Gram-Positive Bacteria; Molecular Sequence Data; Multigene Family; Operon; Peptides, Cyclic; Protein Precursors; Protein Processing, Post-Translational; Protein Sorting Signals; Sulfides | 1995 |
Novel lantibiotics and their pre-peptides.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Gram-Positive Bacteria; Protein Sorting Signals; Sulfides | 1996 |
Chemistry, biochemistry, nutrition, and microbiology of lysinoalanine, lanthionine, and histidinoalanine in food and other proteins.
Topics: Alanine; Animal Nutritional Physiological Phenomena; Animals; Dietary Proteins; Digestion; Dipeptides; Food Analysis; Humans; Lysinoalanine; Mice; Nutritional Physiological Phenomena; Proteins; Rats; Sulfides | 1999 |
Lantibiotics: structure, biosynthesis and mode of action.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Molecular Sequence Data; Peptides; Sulfides | 2001 |
New reagents, reactions, and peptidomimetics for drug design.
Topics: Alanine; Amines; Amino Acids; Drug Design; Enkephalins; Guanidine; Indicators and Reagents; Models, Chemical; Organophosphates; Peptides; Sulfides; Triazines | 2001 |
Bacterial lantibiotics: strategies to improve therapeutic potential.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Bacteria; Molecular Conformation; Molecular Sequence Data; Mutation; Peptides; Sequence Homology, Amino Acid; Sulfhydryl Compounds; Sulfides | 2005 |
Morphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Hyphae; Molecular Sequence Data; Protein Conformation; Streptomyces coelicolor; Sulfides; Surface-Active Agents | 2006 |
A lesson in efficient killing from two-component lantibiotics.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Nisin; Sulfides; Uridine Diphosphate N-Acetylmuramic Acid | 2006 |
Structure-function relationships of the non-lanthionine-containing peptide (class II) bacteriocins produced by gram-positive bacteria.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Bacteriocins; Gram-Positive Bacteria; Humans; Molecular Sequence Data; Peptides; Structure-Activity Relationship; Sulfides | 2009 |
Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides.
Topics: Alanine; Amino Acids; Bacteria; Biosynthetic Pathways; Genetic Engineering; Protein Biosynthesis; Sulfides | 2010 |
Emerging biological importance of central nervous system lanthionines.
Topics: Alanine; Amination; Animals; Central Nervous System; Cystathionine beta-Synthase; Humans; Neuroprotective Agents; Substrate Specificity; Sulfides | 2010 |
Reversible and irreversible protein glutathionylation: biological and clinical aspects.
Topics: Alanine; Aldehydes; Alzheimer Disease; Apoptosis; Busulfan; Cataract; Cell Cycle; Cystic Fibrosis; Diabetes Mellitus, Type 2; Glutathione; Glutathione Disulfide; Glutathione Transferase; Neoplasms; Oxidation-Reduction; Oxidative Stress; Protein Folding; Proteins; Signal Transduction; Sulfides | 2011 |
The challenge of the lantibiotics: synthetic approaches to thioether-bridged peptides.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Biomimetics; Biotransformation; Chemistry, Pharmaceutical; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Polycyclic Compounds; Protein Engineering; Solid-Phase Synthesis Techniques; Sulfides | 2011 |
Nitrone-based therapeutics for neurodegenerative diseases: their use alone or in combination with lanthionines.
Topics: Alanine; Antineoplastic Agents; Benzenesulfonates; Cyclic N-Oxides; Drug Combinations; Free Radicals; Humans; Imines; Neoplasms; Neurodegenerative Diseases; Sulfides | 2013 |
Insights into the evolution of lanthipeptide biosynthesis.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cyclization; Cysteine; Evolution, Molecular; Hydro-Lyases; Multienzyme Complexes; Peptides, Cyclic; Protein Processing, Post-Translational; Serine; Sulfides; Threonine | 2013 |
Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement.
Topics: Alanine; Animals; Brain; Brain Diseases; Cystathionine beta-Synthase; Humans; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Sulfides; Sulfur | 2015 |
Substrate-Controlled Stereochemistry in Natural Product Biosynthesis.
Topics: Acyl Carrier Protein; Alanine; Amino Acid Sequence; Animals; Biological Products; Biosynthetic Pathways; Humans; Models, Molecular; Molecular Sequence Data; Peptides; Peptides, Cyclic; Polyketides; Stereoisomerism; Substrate Specificity; Sulfides | 2015 |
The Sulfur Metabolite Lanthionine: Evidence for a Role as a Novel Uremic Toxin.
Topics: Alanine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Renal Dialysis; Sulfides; Uremia | 2017 |
Progress in Lanthionine and Protected Lanthionine Synthesis.
Topics: Alanine; Chemistry Techniques, Analytical; Molecular Structure; Stereoisomerism; Sulfides | 2018 |
Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors.
Topics: Alanine; Animals; Anti-Bacterial Agents; Bacterial Proteins; Disulfides; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; GTP-Binding Proteins; Humans; Lanthanoid Series Elements; Membrane Transport Proteins; Mice; Peptide Hydrolases; Peptides; Protein Domains; Protein Processing, Post-Translational; Protein Sorting Signals; Rats; Receptors, G-Protein-Coupled; Substrate Specificity; Sulfides | 2020 |
1 trial(s) available for alanine and lanthionine
| Article | Year |
|---|---|
Divergent behavior of hydrogen sulfide pools and of the sulfur metabolite lanthionine, a novel uremic toxin, in dialysis patients.
Topics: Adult; Aged; Alanine; Female; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Sulfides; Uremia | 2016 |
163 other study(ies) available for alanine and lanthionine
| Article | Year |
|---|---|
[Formation of dehydroalanine, lanthionine and lysinoalanine during heat treatment of beta-lactoglobuline A (author's transl)].
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Dipeptides; Female; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Lactoglobulins; Lysine; Sulfides | 1977 |
Demonstration of lanthionine as a natural constituent of the peptidoglycan of Fusobacterium nucleatum.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Amino Sugars; Fusobacterium; Peptidoglycan; Sulfides | 1979 |
Intramolecular cross-linking of proteins by formation of lysinoalanine or lanthionine. Modification of disulfides in ovomucoids.
Topics: Alanine; Alkalies; Amino Acids; Animals; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Egg Proteins; Electrophoresis, Disc; Hexosamines; Hexoses; Lysine; Lysinoalanine; Ovomucin; Poultry; Proteins; Sodium Cyanide; Subtilisins; Sulfhydryl Compounds; Sulfides; Thiocyanates; Trypsin Inhibitors | 1979 |
Lanthionine detected in human urine.
Topics: Alanine; Amino Acids, Sulfur; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Humans; Mass Spectrometry; Methods; Sulfides | 1978 |
Comparative studies on the fermentative production of lantibiotics by staphylococci.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Chromatography, Gel; Culture Media; Fermentation; Microbial Sensitivity Tests; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Peptides, Cyclic; Staphylococcus; Staphylococcus epidermidis; Sulfides | 1990 |
Mode of action of the lanthionine-containing peptide antibiotics duramycin, duramycin B and C, and cinnamycin as indirect inhibitors of phospholipase A2.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteriocins; Binding, Competitive; Circular Dichroism; Humans; Neutrophils; Peptides; Peptides, Cyclic; Phospholipases A; Phospholipases A2; Phospholipids; Substrate Specificity; Sulfides | 1991 |
Direct analysis of the disulfide content of proteins: methods for monitoring the stability and refolding process of cystine-containing proteins.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Cysteine; Cystine; Diazonium Compounds; Drug Stability; Humans; Lysinoalanine; Protein Conformation; Proteins; Reproducibility of Results; Sensitivity and Specificity; Sulfanilic Acids; Sulfides | 1991 |
Peptidoglycan precursor from Fusobacterium nucleatum contains lanthionine.
Topics: Alanine; Carbon Radioisotopes; Chromatography, Gel; Chromatography, High Pressure Liquid; Fusobacterium; Peptidoglycan; Sulfides; Uridine Diphosphate | 1991 |
Interactive NMR and computer simulation studies of lanthionine-ring structures.
Topics: Alanine; Amino Acid Sequence; Computer Simulation; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nisin; Peptides, Cyclic; Protein Conformation; Sulfides | 1989 |
High-performance liquid chromatography of cystathionine, lanthionine and aminoethylcysteine using o-phthaldialdehyde precolumn derivatization.
Topics: Alanine; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Indicators and Reagents; o-Phthalaldehyde; Sulfides | 1989 |
Gallidermin: a new lanthionine-containing polypeptide antibiotic.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Gas Chromatography-Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Peptides; Peptides, Cyclic; Staphylococcus; Sulfides | 1988 |
Lanthionine, a protein cross-link in cataractous human lenses.
Topics: Alanine; Amino Acids; Cataract; Crystallins; Cystine; Humans; Sulfides | 1987 |
The transamination of L-cystathionine, L-cystine and related compounds by a bovine kidney transaminase.
Topics: Alanine; Amino Acids; Animals; Cattle; Cystathionine; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Kidney; Kinetics; Molecular Weight; Rats; Species Specificity; Structure-Activity Relationship; Substrate Specificity; Sulfides; Transaminases | 1986 |
Metabolism of sulfur-containing amino acids in the dermatophyte Microsporum gypseum. I. Neutral amino acids.
Topics: Alanine; Amino Acids, Sulfur; Arginine; Chromatography, Thin Layer; Cysteine; Cystine; Homocystine; Hydrogen-Ion Concentration; Methionine; Microsporum; Sulfates; Sulfides; Sulfites | 1985 |
Structural similarities of the staphylococcin-like peptide Pep-5 to the peptide antibiotic nisin.
Topics: Alanine; Amino Acids; Bacteriocins; Carboxypeptidases; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Nisin; Staphylococcus epidermidis; Sulfides | 1985 |
Studies on the utilization of lysinoalanine and lanthionine.
Topics: Alanine; Amino Acids; Animals; Chickens; Cysteine; Dietary Proteins; Female; Hydrogen-Ion Concentration; Kidney; Lysine; Lysinoalanine; Male; Nutritive Value; Rats; Species Specificity; Structure-Activity Relationship; Sulfides | 1980 |
Composition of peptidoglycans in Bacteroidaceae: determination and distribution of lanthionine.
Topics: Alanine; Amino Acids; Bacteroidaceae; Bacteroides; Fusobacterium; Galactosamine; Glucosamine; Peptidoglycan; Stereoisomerism; Sulfides | 1982 |
L-lanthionine oxidation by snake venom L-amino acid oxidase.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; Crotalid Venoms; L-Amino Acid Oxidase; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Snakes; Sulfides | 1982 |
The tetracyclic lantibiotic actagardine. 1H-NMR and 13C-NMR assignments and revised primary structure.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Carbon Isotopes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Peptides; Protons; Sulfides | 1995 |
Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Cystathionine; Diaminopimelic Acid; Escherichia coli; Molecular Sequence Data; Mutation; Oligopeptides; Peptide Synthases; Peptidoglycan; Substrate Specificity; Sulfides | 1994 |
Elucidation of the structure of SA-FF22, a lanthionine-containing antibacterial peptide produced by Streptococcus pyogenes strain FF22.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Bacteriocins; Circular Dichroism; Endopeptidases; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Structure, Secondary; Streptococcus pyogenes; Sulfides | 1994 |
Directed evolution of biosynthetic pathways. Recruitment of cysteine thioethers for constructing the cell wall of Escherichia coli.
Topics: Alanine; Amino Acid Isomerases; Biological Evolution; Carbon-Oxygen Lyases; Cell Wall; Cystathionine; Diaminopimelic Acid; Escherichia coli; Lyases; Peptidoglycan; Racemases and Epimerases; Sulfides | 1993 |
The mode of action of SA-FF22, a lantibiotic isolated from Streptococcus pyogenes strain FF22.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Bacillus subtilis; Bacteriocins; Biological Transport; Cell Membrane; Kinetics; Membrane Potentials; Peptides; Phospholipids; Spectrometry, Fluorescence; Streptococcus; Streptococcus pyogenes; Sulfides | 1994 |
Isolation and characterization of the lantibiotic salivaricin A and its structural gene salA from Streptococcus salivarius 20P3.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA, Bacterial; Molecular Sequence Data; Plasmids; Streptococcus; Sulfides | 1993 |
Variacin, a new lanthionine-containing bacteriocin produced by Micrococcus varians: comparison to lacticin 481 of Lactococcus lactis.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Bacteriocins; Base Sequence; Lactococcus lactis; Micrococcus; Molecular Sequence Data; Sequence Alignment; Sulfides | 1996 |
Isolation of a new epidermin variant from two strains of Staphylococcus epidermidis--frequency of lantibiotic production in coagulase-negative staphylococci.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Coagulase; Genetic Variation; Mass Spectrometry; Molecular Sequence Data; Peptides; Staphylococcus epidermidis; Sulfides | 1996 |
Effects of the lantibiotic mersacidin on the morphology of staphylococci.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Penicillins; Peptides; Staphylococcus; Sulfides; Tunicamycin; Vancomycin | 1996 |
Proceedings of the 2nd International Workshop on Lantibiotics. Arnhem, The Netherlands, 20-23 November 1994.
Topics: Alanine; Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Humans; Peptides; Sulfides | 1996 |
Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.
Topics: Alanine; Animals; Biotransformation; Cells, Cultured; Drug Design; Growth Hormone; Male; Octreotide; Peptides, Cyclic; Pituitary Gland, Anterior; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Recombinant Proteins; Somatostatin; Spectrometry, Mass, Secondary Ion; Structure-Activity Relationship; Sulfides | 1997 |
A refined model for the somatostatin pharmacophore: conformational analysis of lanthionine-sandostatin analogs.
Topics: Alanine; Amino Acid Sequence; Animals; Calorimetry; Humans; Isomerism; Magnetic Resonance Spectroscopy; Models, Molecular; Octreotide; Peptides, Cyclic; Protein Structure, Secondary; Receptors, Somatostatin; Structure-Activity Relationship; Sulfides; Threonine | 1997 |
Simultaneous determination of urinary cystathionine, lanthionine, S-(2-aminoethyl)-L-cysteine and their cyclic compounds using liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization.
Topics: Alanine; Atmospheric Pressure; Chromatography, Ion Exchange; Cystathionine; Cysteine; Humans; Ions; Mass Spectrometry; Reference Values; Sulfides | 1997 |
Underground metabolism.
Topics: Alanine; Biological Evolution; Energy Metabolism; Enzymes; Genetic Diseases, Inborn; Glutamic Acid; Phenotype; Substrate Specificity; Sulfides | 1998 |
Lanthionine macrocyclization by in situ activation of serine.
Topics: Alanine; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Molecular Structure; Sequence Analysis; Serine; Sulfides | 1998 |
Ab initio structure determination of the lantibiotic mersacidin.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Computer Simulation; Crystallization; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; Peptides; Protein Conformation; Solutions; Static Electricity; Sulfides | 2000 |
Biomimetic synthesis of lantibiotics.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Peptides; Sulfides | 2000 |
Synthesis, conformational analysis and biological activities of lanthionine analogs of a cell adhesion modulator.
Topics: Alanine; Cell Adhesion; Cell Adhesion Molecules; Computer Simulation; Humans; Inhibitory Concentration 50; Integrin alpha4beta1; Integrins; Magnetic Resonance Spectroscopy; Models, Chemical; Peptides; Platelet Aggregation; Protein Conformation; Receptors, Lymphocyte Homing; Sulfides | 2001 |
Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands.
Topics: Alanine; Analgesics; Animals; CHO Cells; Cricetinae; Enkephalins; Escape Reaction; Humans; Ileum; In Vitro Techniques; Injections, Spinal; Male; Mice; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfides; Swine; Vas Deferens | 2002 |
NisB is required for the dehydration and NisC for the lanthionine formation in the post-translational modification of nisin.
Topics: Alanine; Bacterial Proteins; Dehydration; Histidine; Lactococcus lactis; Membrane Proteins; Mutation; Nisin; Protein Processing, Post-Translational; Sulfides | 2002 |
Systemic and spinal analgesic activity of a delta-opioid-selective lanthionine enkephalin analog.
Topics: Alanine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mice; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord; Sulfides | 2003 |
Enantioselective synthesis of alpha-methyl-D-cysteine and lanthionine building blocks via alpha-methyl-D-serine-beta-lactone.
Topics: Alanine; Cysteine; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Serine; Sulfides | 2003 |
[Studies on lanthionine formation from wool and cystine].
Topics: Alanine; Amino Acids; Animals; Cystine; Sulfides; Wool | 1956 |
Studies on the sulfur metabolism of tissues cultivated in vitro. IV. Ergothioneine, oxidized glutathione, and lanthionine.
Topics: Alanine; Amino Acids; Cystine; Ergothioneine; Glutathione; Glutathione Disulfide; In Vitro Techniques; Myocardium; Sulfides; Sulfur | 1958 |
An improved method for the determination of lanthionine.
Topics: Alanine; Amino Acids; Sulfides | 1959 |
Lanthionine formation in keratin.
Topics: Alanine; Amino Acids; Biochemical Phenomena; Keratins; Sulfides | 1961 |
[Decomposition of cystine, cysteine, cystine-dihydantoin, lanthionine and lanthionine-dihydantoin in aqueous solutions].
Topics: Alanine; Amino Acids; Cysteine; Cystine; Hydantoins; Sulfides | 1962 |
DETERMINATION OF LANTHIONINE IN PROTEIN HYDROLYZATES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Cystine; Edetic Acid; Glutamates; Protein Hydrolysates; Research; Sulfides; Sulfonic Acids; Wool | 1964 |
Utilization of sulfur compounds by Streptococcus bovis.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Methionine; Nitrogen; Streptococcus; Streptococcus bovis; Sulfates; Sulfides; Sulfites; Sulfur; Thiosulfates | 1961 |
Synthesis of orthogonally protected lanthionines.
Topics: Alanine; Anti-Bacterial Agents; Molecular Structure; Peptides; Stereoisomerism; Sulfides | 2003 |
Synthesis of a cyclic peptide containing norlanthionine: effect of the thioether bridge on peptide conformation.
Topics: Alanine; Bridged-Ring Compounds; Molecular Structure; Nisin; Peptides, Cyclic; Protein Conformation; Stereoisomerism; Sulfides | 2003 |
Biomimetic studies on the mechanism of stereoselective lanthionine formation.
Topics: Alanine; Amino Acid Sequence; Biomimetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Peptides; Selenocysteine; Stereoisomerism; Sulfides | 2003 |
[On lanthionine formation; a contribution in explanation of priority in the isolation of a diaminothiopropionic acid from keratin].
Topics: Alanine; Keratins; Sulfides | 1951 |
A new procedure for the quantitative splitting of lanthionine to cysteine.
Topics: Alanine; Amino Acids; Cysteine; Sulfides | 1952 |
Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Bacteriocins; Boranes; Deuterium; Drug Synergism; Lactococcus lactis; Molecular Sequence Data; Nickel; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Solutions; Structure-Activity Relationship; Sulfides; Sulfur; Thermodynamics | 2004 |
Dehydroalanine crosslinks in human lens.
Topics: Adult; Aged; Aging; Alanine; Cataract; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Crystallins; Dipeptides; Humans; Lens, Crystalline; Lysinoalanine; Middle Aged; Solubility; Sulfides | 2004 |
An unusual mutation results in the replacement of diaminopimelate with lanthionine in the peptidoglycan of a mutant strain of Mycobacterium smegmatis.
Topics: Alanine; Alleles; Amino Acid Sequence; Base Sequence; Cystathionine beta-Synthase; Diaminopimelic Acid; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Peptidoglycan; Sulfides | 2005 |
Orthogonally protected lanthionines: synthesis and use for the solid-phase synthesis of an analogue of nisin ring C.
Topics: Alanine; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Sulfides | 2005 |
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; DNA Primers; Drug Design; Lactococcus lactis; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Recombinant Proteins; Sulfides | 2005 |
Glutathionylation of lens proteins through the formation of thioether bond.
Topics: Aging; Alanine; Animals; Cattle; Crystallins; Glutathione; Glutathione Disulfide; Humans; Lens, Crystalline; Solutions; Sulfides | 2005 |
Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydro-Lyases; Molecular Sequence Data; Molecular Weight; Peptides; Protein Engineering; Recombinant Proteins; Sulfides | 2005 |
SapT, a lanthionine-containing peptide involved in aerial hyphae formation in the streptomycetes.
Topics: Alanine; Bacterial Proteins; Culture Media; Gene Expression Regulation, Bacterial; Hyphae; Magnetic Resonance Spectroscopy; Models, Molecular; Morphogenesis; Mutation; Peptides; Streptomyces; Streptomyces coelicolor; Sulfides | 2005 |
Lipolanthionine peptides act as inhibitors of TLR2-mediated IL-8 secretion. Synthesis and structure-activity relationships.
Topics: Adjuvants, Immunologic; Alanine; Cell Line; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-8; Magnetic Resonance Spectroscopy; Oligopeptides; Stereoisomerism; Structure-Activity Relationship; Sulfides; Toll-Like Receptor 2 | 2006 |
Comparative species utilization and toxicity of sulfur amino acids.
Topics: Alanine; Amino Acids, Sulfur; Animals; Biological Availability; Cysteine; Cystine; Dietary Supplements; Glutathione; Homocysteine; Humans; Hydroxylation; Isomerism; Methionine; Species Specificity; Sulfides; Taurine; Vitamin U | 2006 |
Stereoselective synthesis of orthogonally protected alpha-methylnorlanthionine.
Topics: Alanine; Amino Acids; Catalysis; Cysteine; Molecular Structure; Nisin; Peptides, Cyclic; Stereoisomerism; Sulfides | 2006 |
Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Bacillus; beta-Defensins; Cell Line; Cell Line, Tumor; Corynebacterium; Cytokines; Diaminopimelic Acid; Epithelial Cells; HeLa Cells; Humans; Inflammation Mediators; Interferon-gamma; Intestinal Mucosa; Monocytes; Mouth Mucosa; Mycobacterium; Nod1 Signaling Adaptor Protein; Peptidoglycan; RNA, Messenger; RNA, Small Interfering; Stereoisomerism; Sulfides; Up-Regulation | 2006 |
Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriocins; Cyclization; Dehydration; Enzyme Activation; Enzymes; Molecular Conformation; Molecular Sequence Data; Mutation; Peptides; Protein Engineering; Sensitivity and Specificity; Sulfides | 2006 |
Step-wise and pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis.
Topics: Alanine; Alkenes; Amino Acid Sequence; Catalysis; Chemistry, Organic; Mass Spectrometry; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Nisin; Peptides; Sulfides | 2007 |
Rhenium analogues of promising renal imaging agents with a [99mTc(CO)3]+ core bound to cysteine-derived dipeptides, including lanthionine.
Topics: Alanine; Crystallography, X-Ray; Cysteine; Dipeptides; Kidney; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Organometallic Compounds; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Rhenium; Sensitivity and Specificity; Sulfides | 2007 |
A concise stereoselective synthesis of orthogonally protected lanthionine and beta-methyllanthionine.
Topics: Alanine; Bacteriocins; Molecular Structure; Stereoisomerism; Sulfides | 2007 |
Hair is the news.
Topics: Alanine; Amino Acids; Ammonia; Animals; Cysteine; Hair; Hair Follicle; Humans; Sulfides | 2007 |
Stereoselective syntheses of 4-oxa diaminopimelic acid and its protected derivatives via aziridine ring opening.
Topics: Alanine; Amino Acids; Aziridines; Catalysis; Diaminopimelic Acid; Haemophilus influenzae; Molecular Structure; Racemases and Epimerases; Serine; Stereoisomerism; Sulfides; Threonine | 2007 |
Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Animals, Newborn; Cell Line; Cloning, Molecular; Diaminopimelic Acid; Humans; Molecular Sequence Data; Nod1 Signaling Adaptor Protein; Peyer's Patches; Stereoisomerism; Sulfides; Swine | 2008 |
Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Cell Membrane; Coated Vesicles; Diphosphates; Fluoresceins; Lactococcus lactis; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Succinic Acid; Sulfides; Tryptophan; Uridine Diphosphate N-Acetylmuramic Acid | 2008 |
The importance of the leader sequence for directing lanthionine formation in lacticin 481.
Topics: 5' Untranslated Regions; Alanine; Amino Acid Sequence; Aminobutyrates; Bacteriocins; Conserved Sequence; DNA Primers; Enzymes; Gene Expression; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sulfides | 2008 |
Complete covalent structure of nisin Q, new natural nisin variant, containing post-translationally modified amino acids.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Bacteriocins; Magnetic Resonance Spectroscopy; Molecular Structure; Nisin; Protein Processing, Post-Translational; Sulfides | 2008 |
The availability of dl-lanthionine for the promotion of growth in young rats when added to a cystine- and methionine-deficient diet.
Topics: Alanine; Animals; Cystine; Diet; Methionine; Rats; Sulfides | 1948 |
Availability of dl-lanthionine for the promotion of growth when added to a cystine-deficient diet.
Topics: Alanine; Cystine; Diet; Growth; Humans; Sulfides | 1948 |
Concise preparation of tetra-orthogonally protected (2S,6R)-lanthionines.
Topics: Alanine; Bacteriocins; Stereoisomerism; Sulfides | 2009 |
Oxidation of lanthionines renders the lantibiotic nisin inactive.
Topics: Alanine; Anti-Bacterial Agents; Macromolecular Substances; Mass Spectrometry; Microbial Sensitivity Tests; Micrococcus luteus; Microscopy, Electron; Models, Molecular; Nisin; Oxidation-Reduction; Staphylococcus aureus; Streptococcus pneumoniae; Sulfides; Uridine Diphosphate N-Acetylmuramic Acid | 2009 |
Characterization of alkali induced formation of lanthionine, trisulfides, and tetrasulfides from peptide disulfides using negative ion mass spectrometry.
Topics: Alanine; Glutathione Disulfide; Peptides, Cyclic; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Sulfides | 2009 |
Two novel bovine somatotropin species generated from a common dehydroalanine intermediate.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Chromatography, Ion Exchange; Growth Hormone; Hydrogen-Ion Concentration; Lysinoalanine; Molecular Sequence Data; Peptide Mapping; Protein Conformation; Protein Multimerization; Sequence Analysis, Protein; Sulfides; Tandem Mass Spectrometry | 2009 |
H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia.
Topics: Alanine; Catalysis; Cystathionine gamma-Lyase; Cysteine; Dose-Response Relationship, Drug; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Hyperhomocysteinemia; Kinetics; Mass Spectrometry; Models, Chemical; Recombinant Proteins; Sulfides; Sulfur; Temperature | 2009 |
Chapter 21. In vitro studies of lantibiotic biosynthesis.
Topics: Alanine; Aminobutyrates; Bacteriocins; Molecular Structure; Sulfides | 2009 |
Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions.
Topics: Alanine; Chromatography, High Pressure Liquid; Computer Simulation; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Humans; Hydrogen Sulfide; Kinetics; Mass Spectrometry; Models, Biological; Models, Chemical; Molecular Conformation; Serine; Sulfides; Sulfur | 2009 |
Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin.
Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Lactococcus lactis; Membrane Proteins; Multienzyme Complexes; Nisin; Peptide Biosynthesis, Nucleic Acid-Independent; Sulfides | 2009 |
Commentary: healthy hair and protein loss.
Topics: Alanine; Carbonates; Cystine; Guanidine; Hair; Hair Diseases; Hair Preparations; Lye; Proteins; Scalp Dermatoses; Sulfides | 2010 |
The action of formaldehyde on the cystine disulphide linkage of wool; the conversion of subfraction A of the combined cystine into combined lanthionine and djenkolic acid and subfraction B into combined thiazolidine-4-carboxylic acid.
Topics: Alanine; Animals; Cysteine; Cystine; Formaldehyde; Humans; Sulfides; Thiazolidines; Wool | 1947 |
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.
Topics: Alanine; Amino Acid Sequence; Bacteria; Bacterial Proteins; Bacteriocins; Evolution, Molecular; Isoenzymes; Ligases; Molecular Sequence Data; Molecular Structure; Multigene Family; Phylogeny; Protein Conformation; Protein Processing, Post-Translational; RNA, Ribosomal, 16S; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces; Sulfides | 2010 |
Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586.
Topics: Alanine; Ammonia; Aspartate Aminotransferases; Bacterial Proteins; Cysteine Synthase; Fusobacterium nucleatum; Homocysteine; Hydrogen Sulfide; Kinetics; Pyruvic Acid; Substrate Specificity; Sulfides | 2010 |
The kinetics of β-elimination of cystine and the formation of lanthionine in gliadin.
Topics: Alanine; Cystine; Disulfides; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Sulfides | 2010 |
Effect of bioengineering lacticin 3147 lanthionine bridges on specific activity and resistance to heat and proteases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacteriocins; Bioengineering; Hot Temperature; Peptide Hydrolases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides | 2010 |
Ruminococcin C, a new anti-Clostridium perfringens bacteriocin produced in the gut by the commensal bacterium Ruminococcus gnavus E1.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Bacteriocins; Cecum; Clostridium perfringens; Genes, Bacterial; Hot Temperature; Hydrogen-Ion Concentration; Intestines; Microbial Sensitivity Tests; Molecular Sequence Data; Rats; Ruminococcus; Sulfides | 2011 |
Application of XANES profiles to X-ray spectromicroscopy for biomedical specimens: Part I. Discrimination of macromolecules with sulfur atoms.
Topics: Alanine; Animals; Cattle; Cysteine; Cystine; Glutathione; Hemoglobins; Histones; Macromolecular Substances; Methionine; Molecular Conformation; Serum Albumin, Bovine; Spectrometry, X-Ray Emission; Sulfides; Sulfur Compounds | 2011 |
Synthesis of peptides containing overlapping lanthionine bridges on the solid phase: an analogue of rings D and E of the lantibiotic nisin.
Topics: Alanine; Amino Acid Sequence; Nisin; Peptides; Sulfides | 2011 |
Cross-linking of wheat gluten proteins during production of hard pretzels.
Topics: Alanine; Chromatography, Ion Exchange; Cross-Linking Reagents; Cysteine; Cystine; Food Handling; Food Technology; Glutens; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Maillard Reaction; Reducing Agents; Sodium Dodecyl Sulfate; Sodium Hydroxide; Sulfides; Triticum | 2012 |
A biomimetic approach to lanthionines.
Topics: Alanine; Amino Acids; Biomimetic Materials; Molecular Structure; Stereoisomerism; Sulfides | 2012 |
Characterization of new class III lantibiotics--erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Genes, Bacterial; Mass Spectrometry; Molecular Sequence Data; Saccharopolyspora; Streptomyces; Streptomyces griseus; Sulfides | 2012 |
Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Gas Chromatography-Mass Spectrometry; Genes, Bacterial; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Prochlorococcus; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Stereoisomerism; Sulfides | 2012 |
Biosynthesis of the class III lantipeptide catenulipeptin.
Topics: Actinobacteria; Alanine; Amino Acid Sequence; Genes, Bacterial; Molecular Sequence Data; Multigene Family; Peptides; Protein Sorting Signals; Streptomyces coelicolor; Sulfides | 2012 |
Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase.
Topics: Actinomycetales; Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Biological Products; Chromatography, High Pressure Liquid; Ligases; Mass Spectrometry; Molecular Sequence Data; Multigene Family; Peptides, Cyclic; Protein Precursors; Substrate Specificity; Sulfides | 2012 |
Characterization of therapeutic monoclonal antibodies reveals differences between in vitro and in vivo time-course studies.
Topics: Alanine; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Chromatography, Liquid; Humans; Immunoglobulin G; Lysine; Pyrrolidonecarboxylic Acid; Rats; Sulfides; Tandem Mass Spectrometry | 2013 |
The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry.
Topics: Alanine; Enterococcus; Molecular Conformation; Perforin; Stereoisomerism; Sulfides | 2013 |
The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.
Topics: Alanine; Animals; Cystathionine; Cysteine; Cysteine Dioxygenase; Diet; Electron Transport Complex IV; Enzyme Stability; Female; Glutathione; Hydrogen Sulfide; Kidney; Liver; Lung; Male; Mice; Mice, Knockout; Organ Specificity; Pancreas; Sulfides; Taurine | 2013 |
Characterization of the congeners in the lantibiotic NAI-107 complex.
Topics: Actinomycetales; Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Drug Resistance, Bacterial; Molecular Structure; Multigene Family; Sulfides | 2014 |
Novel LanT associated lantibiotic clusters identified by genome database mining.
Topics: Actinobacteria; Alanine; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; Data Mining; Databases, Genetic; Genes, Bacterial; Genomics; Multigene Family; Quorum Sensing; Sulfides | 2014 |
Effects of pH and lactate on hydrogen sulfide production by oral Veillonella spp.
Topics: Alanine; Ammonia; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Lactic Acid; Serine; Sulfides; Veillonella | 2014 |
Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Biocatalysis; Cyclization; Ligases; Molecular Sequence Data; Peptides, Cyclic; Prochlorococcus; Protein Processing, Post-Translational; Solid-Phase Synthesis Techniques; Substrate Specificity; Sulfides | 2014 |
Stereoselective synthesis of lanthionine derivatives in aqueous solution and their incorporation into the peptidoglycan of Escherichia coli.
Topics: Alanine; Escherichia coli; Molecular Structure; Peptidoglycan; Solutions; Stereoisomerism; Sulfides; Water | 2014 |
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Linear Models; Liver Neoplasms; Pyridoxal Phosphate; Sulfides; Vitamin B 6; Vitamin B 6 Deficiency | 2014 |
Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment.
Topics: Alanine; Anti-Bacterial Agents; Bacillus subtilis; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Conformation; Nisin; Structure-Activity Relationship; Sulfides | 2014 |
Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteriocins; Carnobacteriaceae; Enterococcus; Methylation; Molecular Sequence Data; Perforin; Sulfides | 2014 |
High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis.
Topics: Alanine; Amino Acid Sequence; Combinatorial Chemistry Techniques; Molecular Sequence Data; Peptides; Sequence Homology, Amino Acid; Sulfides | 2014 |
Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt.
Topics: Alanine; Apoptosis; Blotting, Western; Cell Line, Transformed; Cell Survival; HEK293 Cells; Hep G2 Cells; Humans; Mechanistic Target of Rapamycin Complex 2; Membrane Proteins; Microscopy, Fluorescence; Multiprotein Complexes; Nuclear Proteins; Phosphate-Binding Proteins; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; RNA Interference; Sulfides; TOR Serine-Threonine Kinases | 2014 |
Enantioselective synthesis of α-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycan.
Topics: Alanine; Escherichia coli; Molecular Structure; Oligopeptides; Peptidoglycan; Stereoisomerism; Sulfides | 2014 |
A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.
Topics: Alanine; Biological Assay; Kinetics; Ligases; Models, Molecular; Molecular Structure; Peptides; Protein Processing, Post-Translational; Substrate Specificity; Sulfides | 2014 |
Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5: conformational analysis, dimerisation and consequences for receptor activation.
Topics: Alanine; Antineoplastic Agents; Apoptosis; Chemistry Techniques, Synthetic; Dimerization; Disulfides; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Molecular Targeted Therapy; Peptides, Cyclic; Protein Conformation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sulfides; Surface Plasmon Resonance | 2015 |
Natural product biosynthesis: the road to L.
Topics: Alanine; Sulfides | 2015 |
Substrate control in stereoselective lanthionine biosynthesis.
Topics: Alanine; Amino Acid Sequence; Cyclization; Gas Chromatography-Mass Spectrometry; Molecular Sequence Data; Protein Structure, Secondary; Quantum Theory; Stereoisomerism; Substrate Specificity; Sulfides; Thermodynamics | 2015 |
GRPR-selective PET imaging of prostate cancer using [(18)F]-lanthionine-bombesin analogs.
Topics: Alanine; Animals; Bombesin; Cell Line, Tumor; Fluorine Radioisotopes; Humans; Male; Mice, Nude; Neoplasm Transplantation; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Receptors, Bombesin; Sulfides; Tissue Distribution; X-Ray Microtomography | 2015 |
Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria.
Topics: Actinobacteria; Alanine; Biological Products; Biosynthetic Pathways; Multigene Family; Sulfides | 2015 |
In vitro catalytic activity of N-terminal and C-terminal domains in NukM, the post-translational modification enzyme of nukacin ISK-1.
Topics: Alanine; Bacteriocins; Biocatalysis; Cyclization; Enzymes; Nisin; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Staphylococcus; Substrate Specificity; Sulfides | 2015 |
Streptocollin, a Type IV Lanthipeptide Produced by Streptomyces collinus Tü 365.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Chromatography, High Pressure Liquid; Molecular Sequence Data; Multigene Family; Peptides; Promoter Regions, Genetic; Protein Structure, Secondary; Sequence Alignment; Streptomyces; Sulfides; Tandem Mass Spectrometry | 2015 |
Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency.
Topics: Actinobacteria; Actinomycetales; Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Gram-Positive Bacteria; Hydrocarbons, Brominated; Microbial Sensitivity Tests; Microsporidia; Molecular Structure; Peptides; Sulfides | 2015 |
Identification of lanthionine and lysinoalanine in heat-treated wheat gliadin and bovine serum albumin using tandem mass spectrometry with higher-energy collisional dissociation.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Cysteine; Cystine; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Proteolysis; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Triticum; Trypsin | 2016 |
Thioethers as markers of hydrogen sulfide production in homocystinurias.
Topics: Alanine; Cells, Cultured; Cystathionine; Cystathionine beta-Synthase; Female; Fibroblasts; Homocystinuria; Humans; Hydrogen Sulfide; Male; Sulfides | 2016 |
Discovery and Characterization of Bicereucin, an Unusual d-Amino Acid-Containing Mixed Two-Component Lantibiotic.
Topics: Alanine; Animals; Anti-Bacterial Agents; Bacillus cereus; Bacteriocins; Cysteine; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxidoreductases; Peptides; Protein Sorting Signals; Rabbits; Recombinant Proteins; Sulfides; Vancomycin-Resistant Enterococci | 2016 |
Characterization of the stereochemical configuration of lanthionines formed by the lanthipeptide synthetase GeoM.
Topics: Alanine; Bacteriocins; Escherichia coli; Peptide Synthases; Sulfides | 2016 |
The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis.
Topics: Alanine; Enterococcus; Ligases; Perforin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Substrate Specificity; Sulfides | 2016 |
The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins.
Topics: Alanine; Busulfan; Cysteine; Humans; Myeloablative Agonists; Sulfides; Tandem Mass Spectrometry | 2016 |
LanCL proteins are not Involved in Lanthionine Synthesis in Mammals.
Topics: Alanine; Animals; Brain Chemistry; Mass Spectrometry; Membrane Proteins; Mice; Mice, Knockout; Phosphate-Binding Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfides | 2017 |
Recognizing and Predicting Thioether Bridges Formed by Lanthionine and β-Methyllanthionine in Lantibiotics Using a Random Forest Approach with Feature Selection.
Topics: Alanine; Bacteriocins; Databases, Protein; Machine Learning; Sulfides | 2017 |
Evolutionary radiation of lanthipeptides in marine cyanobacteria.
Topics: Alanine; Bayes Theorem; Biological Products; Cluster Analysis; Computational Biology; Cyanobacteria; Evolution, Molecular; Genetic Variation; Genome; Monte Carlo Method; Peptides; Peptides, Cyclic; Photosynthesis; Phylogeny; Polymerase Chain Reaction; Prochlorococcus; Sulfides; Synechococcus | 2017 |
Substrate Specificity of the Secreted Nisin Leader Peptidase NisP.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Biocatalysis; Enzyme Activation; Lactococcus lactis; Membrane Proteins; Methylation; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Nisin; Peptide Fragments; Protein Processing, Post-Translational; Protein Sorting Signals; Proteolysis; Recombinant Proteins; Substrate Specificity; Subtilisins; Sulfides | 2017 |
Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase.
Topics: Alanine; Animals; Biomarkers; Catalysis; Cystathionine beta-Synthase; Cysteine; Haplorhini; Homocysteine; Hydrogen Sulfide; Kinetics; Mice; Mice, Knockout; Serine; Sulfides; Sulfur | 2018 |
Electron transfer dissociation of synthetic and natural peptides containing lanthionine/methyllanthionine bridges.
Topics: Alanine; Cyanogen Bromide; Disulfides; Electron Transport; Nisin; Peptides; Sulfides; Tandem Mass Spectrometry | 2018 |
Zebrafish, a Novel Model System to Study Uremic Toxins: The Case for the Sulfur Amino Acid Lanthionine.
Topics: Alanine; Animals; Disease Models, Animal; Organogenesis; Sulfides; Toxins, Biological; Uremia; Xenobiotics; Zebrafish | 2018 |
The Enzymology of Prochlorosin Biosynthesis.
Topics: Alanine; Alkynes; Aquatic Organisms; Cyanobacteria; Cyclization; Cysteine; Kinetics; Peptides; Prochlorococcus; Protein Engineering; Recombinant Proteins; Substrate Specificity; Sulfides; Zinc | 2018 |
Advanced glycation end products, protein crosslinks and post translational modifications in pork subjected to different heat treatments.
Topics: Alanine; Animals; Cooking; Dietary Proteins; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Maillard Reaction; Muscle Proteins; Nutritive Value; Peptides; Protein Processing, Post-Translational; Protein Stability; Red Meat; Sulfides; Swine; Taste | 2018 |
A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves.
Topics: Alanine; Alkylation; Molecular Conformation; Peptides; Sulfides; Sulfonic Acids | 2018 |
Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models.
Topics: Alanine; Angiotensin I; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Insulin; Mice; Mice, Inbred C57BL; Peptide Fragments; Streptozocin; Sulfides; Treatment Outcome | 2019 |
Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale.
Topics: Alanine; Anti-Bacterial Agents; Bacteria; Drug Design; Microbial Sensitivity Tests; Peptides; Protein Engineering; Sulfides | 2019 |
Assessing the Flexibility of the Prochlorosin 2.8 Scaffold for Bioengineering Applications.
Topics: Alanine; Amino Acid Sequence; Cyclization; Mutagenesis, Site-Directed; Oligopeptides; Peptides, Cyclic; Protein Engineering; Protein Processing, Post-Translational; Sulfides | 2019 |
Uremic Toxin Lanthionine Interferes with the Transsulfuration Pathway, Angiogenetic Signaling and Increases Intracellular Calcium.
Topics: Alanine; Amino Acids, Sulfur; Calcium; Cell Line; Cystathionine beta-Synthase; Endothelial Cells; Flow Cytometry; Gene Expression Regulation; Glutathione; Humans; Hydrogen Sulfide; MicroRNAs; Neovascularization, Physiologic; Oxidation-Reduction; Renal Insufficiency, Chronic; Sulfides; Uremia; Vascular Endothelial Growth Factor A | 2019 |
Addition of cyclic angiotensin-(1-7) to angiotensin-converting enzyme inhibitor therapy has a positive add-on effect in experimental diabetic nephropathy.
Topics: Alanine; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Half-Life; Humans; Kidney Glomerulus; Lisinopril; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Peptide Fragments; Peptides, Cyclic; Proteinuria; Sulfides | 2019 |
Structural and Kinetic Insight into the Biosynthesis of H
Topics: Alanine; Bacterial Proteins; Cystathionine beta-Synthase; Cysteine; Cysteine Synthase; Fusobacterium nucleatum; Humans; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Multienzyme Complexes; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfides; Yeasts | 2019 |
Topics: Alanine; Amino Acid Sequence; Biocatalysis; Imides; Methyltransferases; Models, Molecular; Peptides; Protein Conformation; Streptomyces; Sulfides | 2019 |
Lanthionine Peptides by
Topics: Alanine; Alkylation; Molecular Structure; Peptides; Sulfides; Sulfonic Acids | 2019 |
Whole genome mining reveals a diverse repertoire of lanthionine synthetases and lanthipeptides among the genus Paenibacillus.
Topics: Alanine; Bacterial Proteins; Genome, Bacterial; Ligases; Multigene Family; Paenibacillus; Peptides; Sulfides | 2020 |
Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation.
Topics: Alanine; Amino Acid Sequence; Animals; Antigens, Plant; Artemisia; Carrier Proteins; Cross Reactions; Cysteine; Epitopes; Escherichia coli; Food Hypersensitivity; Humans; Immunoglobulin E; Immunoglobulin G; Mice; Plant Proteins; Pollen; Prunus; Sulfides | 2019 |
Roseocin, a novel two-component lantibiotic from an actinomycete.
Topics: Actinobacteria; Alanine; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Escherichia coli; Genome, Bacterial; Multigene Family; Recombinant Proteins; Streptomyces; Sulfides | 2020 |
Complete synthesis of the bicyclic ring of a mutacin analog with orthogonally protected lanthionine via solid-phase intracyclization.
Topics: Alanine; Bacteriocins; Molecular Conformation; Solid-Phase Synthesis Techniques; Sulfides | 2019 |
High-Throughput Screening for Substrate Specificity-Adapted Mutants of the Nisin Dehydratase NisB.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; High-Throughput Screening Assays; Lactococcus lactis; Ligands; Membrane Proteins; Mutagenesis, Site-Directed; Peptides; Protein Binding; Streptavidin; Substrate Specificity; Sulfides | 2020 |
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming.
Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopamine; Early Diagnosis; Epigenesis, Genetic; Female; Fetal Development; Gestational Age; Glucose Tolerance Test; Glucuronides; Humans; Hypoglycemic Agents; Lactones; Lysine; Meglutol; Metabolomics; Neopterin; Orotic Acid; Phenols; Pregnancy; Ribonucleosides; Sulfides | 2021 |
Genomic analysis suggests Salinispora is a rich source of novel lanthipeptides.
Topics: Alanine; Bacterial Proteins; Genome, Bacterial; Genomics; Micromonosporaceae; Peptide Fragments; Sulfides | 2020 |
LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study.
Topics: Alanine; Angiotensin I; Animals; Arthropod Proteins; Dogs; Dose-Response Relationship, Drug; Healthy Volunteers; Humans; Oligopeptides; Peptide Fragments; Peptides; Proteolysis; Rats; Receptors, G-Protein-Coupled; Sulfides | 2021 |
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome.
Topics: Alanine; Aminobutyrates; Animals; Antimicrobial Cationic Peptides; Female; Glutathione; HEK293 Cells; Humans; Male; MAP Kinase Kinase 1; Membrane Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Phosphate-Binding Proteins; Phosphorylation; Protein Domains; Proteome; Receptors, G-Protein-Coupled; Sulfides | 2021 |
Nocathioamides, Uncovered by a Tunable Metabologenomic Approach, Define a Novel Class of Chimeric Lanthipeptides.
Topics: Alanine; Computational Biology; Data Mining; Genome, Bacterial; Isotopes; Magnetic Resonance Spectroscopy; Multigene Family; Nocardia; Peptides; Protein Conformation; Protein Processing, Post-Translational; Ribosomes; Sulfides; Tandem Mass Spectrometry; Thioamides | 2021 |
Functional Expression and Characterization of the Highly Promiscuous Lanthipeptide Synthetase SyncM, Enabling the Production of Lanthipeptides with a Broad Range of Ring Topologies.
Topics: Alanine; Amino Acids; Cloning, Molecular; Cyclization; Lactococcus lactis; Ligases; Peptides; Protein Conformation; Substrate Specificity; Sulfides | 2021 |
Microwave Heating Promotes the S-Alkylation of Aziridine Catalyzed by Molecular Sieves: A Post-Synthetic Approach to Lanthionine-Containing Peptides.
Topics: Alanine; Alkylation; Aziridines; Catalysis; Chromatography, Gel; Chromatography, Liquid; Cysteine; Heating; Microwaves; Molecular Structure; Peptides; Sulfides | 2021 |
Substrate Sequence Controls Regioselectivity of Lanthionine Formation by ProcM.
Topics: Alanine; Amino Acid Sequence; Models, Molecular; Peptides; Protein Conformation; Sulfides | 2021 |
Mechanistic Studies on Dehydration in Class V Lanthipeptides.
Topics: Alanine; Bacteriocins; Dehydration; Kanamycin Kinase; Ligases; Lyases; Peptides; Phosphates; Protein Sorting Signals; Sulfides | 2022 |
Modular Use of the Uniquely Small Ring A of Mersacidin Generates the Smallest Ribosomally Produced Lanthipeptide.
Topics: Alanine; Bacteriocins; Peptides; Sulfides | 2022 |
Class V Lanthipeptide Cyclase Directs the Biosynthesis of a Stapled Peptide Natural Product.
Topics: Alanine; Bacteriocins; Biological Products; Peptides; Peptides, Cyclic; Sulfides | 2022 |
CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells.
Topics: Alanine; Animals; Artificial Cells; Autophagy; Mammals; Microtubule-Associated Proteins; Motor Neurons | 2023 |