alanine has been researched along with l 685458 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Komano, H; Kurono, Y; Maeda, Y; Nishimura, M; Sai, X; Shiraishi, H; Wang, HQ; Yanagisawa, K | 1 |
| Borgegard, T; Eriksson, H; Johansson, J; Juréus, A; Klintenberg, R; Li, T; Lundkvist, J; Malinowsky, D; Nord, J; Olsson, F; Parpal, S; Paulsen, K; Radesater, AC; Regner, A; Rosqvist, S; Rotticci, D; Sabirsh, A; Singh, R; Stromberg, K; Waldman, M; Yan, H | 1 |
| Chiu, YW; Fukumori, A; Ihara, Y; Ikeuchi, T; Kodama, TS; Kudo, T; Matsuura, Y; Mizuta, N; Nishitomi, K; Okamoto, T; Okochi, M; Oyama, H; Sakaguchi, G; Tagami, S; Takami, M; Takeda, M; Yanagida, K | 1 |
3 other study(ies) available for alanine and l 685458
| Article | Year |
|---|---|
PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Blotting, Western; Carbamates; Cell Line; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; gamma-Aminobutyric Acid; Gene Expression Regulation; Membrane Glycoproteins; Membrane Proteins; Mice; Peptide Fragments; Presenilin-1; Presenilin-2; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Radioimmunoassay; Statistics, Nonparametric; Transgenes; Triglycerides | 2004 |
First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Azepines; Binding, Competitive; Brain; Carbamates; Cell-Free System; Dibenzazepines; Dipeptides; Drug Interactions; Female; Flurbiprofen; Guinea Pigs; HEK293 Cells; Humans; Imidazoles; Mice; Mice, Inbred C57BL; Piperidines; Protein Binding; Protein Processing, Post-Translational; Pyrans; Pyridines; Pyrimidines; Rats; Receptor, EphA4; Receptor, EphB2; Receptors, Notch; Sulfonamides; Sulindac | 2012 |
Semagacestat Is a Pseudo-Inhibitor of γ-Secretase.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Azepines; Carbamates; Cell Differentiation; Clinical Trials as Topic; Dipeptides; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Mice; Neurons | 2017 |