alanine and guanosine 5'-o-(3-thiotriphosphate)

alanine has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (55.00)18.2507
2000's8 (40.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gallagher, JP; Zheng, F1
Bigl, V; Grantyn, R; Rothe, T1
Audigier, Y; Bockaert, J; Nebout, I; Pantaloni, C; van der Neut, R1
Kennedy, ME; Limbird, LE1
Boekhoff, I; Breer, H; Restrepo, D1
Sahara, Y; Westbrook, GL1
Cerione, RA; Erickson, JW; Mittal, R1
Berghuis, AM; Gilman, AG; Lee, E; Raw, AS; Sprang, SR1
Han, M; Lin, SW; Minkova, M; Sakmar, TP; Smith, SO1
Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y1
Matalon, R; Warner, DR; Weinstein, LS; Weng, G; Yu, S1
Cummings, D; Jesaitis, AJ; Miettinen, HM; Mills, JS1
Ebersole, BJ; Flanagan, CA; Kitanovic, S; Sealfon, SC; Yuen, T1
Audinot, V; Beauverger, P; Boutin, JA; Canet, E; Fauchere, JL; Galizzi, JP; Imbert, J; Lahaye, C; Lamamy, V; Levens, N; Nahon, JL; Ouvry, C; Rique, H; Rodriguez, M; Suply, T1
Graber, SG; Hazard, S; Lanier, SM; Peterson, YK1
Denef, C; Langouche, L; Pals, K1
Brillet, K; Kieffer, BL; Massotte, D1
Alves, ID; Eaton, MC; Hruby, VJ; Navratilova, E; Roeske, WR; Stropova, D; Varga, EV; Waite, S; Yamamura, HI1
Benned-Jensen, T; Rosenkilde, MM1
Aldrich, JV; Joshi, AA; Murray, TF1

Other Studies

20 other study(ies) available for alanine and guanosine 5'-o-(3-thiotriphosphate)

ArticleYear
Metabotropic glutamate receptors are required for the induction of long-term potentiation.
    Neuron, 1992, Volume: 9, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alanine; Aminobutyrates; Animals; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Male; Microinjections; Neurons; Organ Culture Techniques; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Time Factors

1992
Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 426, Issue:1-2

    Topics: Alanine; Aminobutyrates; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Fluid; Mice; omega-Conotoxin GVIA; Organophosphorus Compounds; Peptides; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells

1994
Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alanine; Animals; Base Sequence; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Cholera Toxin; Enzyme Activation; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Myristic Acid; Myristic Acids; Oligodeoxyribonucleotides; Plasmids; Polymerase Chain Reaction; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Adrenergic, beta; RNA, Messenger; Transcription, Genetic

1993
Mutations of the alpha 2A-adrenergic receptor that eliminate detectable palmitoylation do not perturb receptor-G-protein coupling.
    The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

    Topics: Acylation; Alanine; Allosteric Regulation; Amino Acid Sequence; Animals; Cell Line; Chromatography, Affinity; Cysteine; Dogs; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Kidney; Kinetics; Mutagenesis, Site-Directed; Palmitic Acid; Palmitic Acids; Receptors, Adrenergic, beta; Recombinant Proteins; Serine; Swine; Transfection; Yohimbine

1993
Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Alanine; Amino Acids; Animals; Cilia; Cyclic AMP; Cyclic GMP; Cysteine; Epithelium; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ictaluridae; Inositol 1,4,5-Trisphosphate; Kinetics; Olfactory Mucosa; Second Messenger Systems; Thionucleotides

1993
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:7

    Topics: Alanine; Animals; Animals, Newborn; Barium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Kinetics; Membrane Potentials; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tetrodotoxin; Time Factors; Virulence Factors, Bordetella

1993
Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.
    Science (New York, N.Y.), 1996, Mar-08, Volume: 271, Issue:5254

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Alanine; Animals; Base Sequence; Cattle; Enzyme Activation; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Rhodopsin; Transducin

1996
Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis.
    Structure (London, England : 1993), 1996, Nov-15, Volume: 4, Issue:11

    Topics: Alanine; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glycine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Magnesium; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Mutation; Phosphates; Protein Conformation; Protein Structure, Secondary

1996
Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.
    The Journal of biological chemistry, 1996, Dec-13, Volume: 271, Issue:50

    Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Phenylalanine; Rhodopsin; Rod Opsins; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Transducin

1996
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
    Brain research, 1997, Apr-18, Volume: 754, Issue:1-2

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine

1997
A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
    The Journal of biological chemistry, 1998, Sep-11, Volume: 273, Issue:37

    Topics: Adenylyl Cyclases; Adult; Alanine; Aluminum Compounds; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Cloning, Molecular; Erythrocyte Membrane; Escherichia coli; Exons; Female; Fibrous Dysplasia, Polyostotic; Fluorides; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tryptophan

1998
Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Alanine; Animals; Anti-HIV Agents; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enfuvirtide; Guanosine 5'-O-(3-Thiotriphosphate); HIV Envelope Protein gp41; Humans; Kinetics; Leucine; Ligands; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Peptide Biosynthesis; Peptide Fragments; Phenylalanine; Protein Binding; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium; Tryptophan

2000
Insertional mutagenesis of the arginine cage domain of the gonadotropin-releasing hormone receptor.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:3

    Topics: Alanine; Amino Acid Motifs; Animals; Arginine; COS Cells; Epitopes; Gonadotropin-Releasing Hormone; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Mutagenesis, Insertional; Protein Structure, Tertiary; Receptors, LHRH; Recombinant Proteins

2001
Structure-activity relationship studies of melanin-concentrating hormone (MCH)-related peptide ligands at SLC-1, the human MCH receptor.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Alanine; Amino Acid Sequence; Calcium; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; Cyclic AMP; Disulfides; Dose-Response Relationship, Drug; Gene Deletion; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypothalamic Hormones; Inhibitory Concentration 50; Kinetics; Ligands; Melanins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Pituitary Hormones; Protein Binding; Receptors, Pituitary Hormone; Receptors, Somatostatin; Saponins; Structure-Activity Relationship; Temperature; Transfection

2001
Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins.
    The Journal of biological chemistry, 2002, Mar-01, Volume: 277, Issue:9

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Cell Line; Dimerization; Dose-Response Relationship, Drug; Glutathione Transferase; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Inhibitory Concentration 50; Insecta; Magnesium; Molecular Sequence Data; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction

2002
Structure-activity relationship and signal transduction of gamma-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor.
    Peptides, 2002, Volume: 23, Issue:6

    Topics: Alanine; Amino Acid Sequence; Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; gamma-MSH; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Peptides; Pertussis Toxin; Rats; Receptors, Corticotropin; Receptors, Melanocortin; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Transfection

2002
Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.
    BMC pharmacology, 2003, Dec-01, Volume: 3

    Topics: Alanine; Cells, Cultured; Cysteine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Mutation; Narcotic Antagonists; Receptors, Opioid, mu; Sulfur Radioisotopes

2003
Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.
    Molecular pharmacology, 2007, Volume: 71, Issue:5

    Topics: Alanine; Animals; Arrestins; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Endocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Models, Biological; Mutation; Oligopeptides; Phosphorylation; Receptors, Opioid, delta; Serine; Time Factors

2007
Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Cell Line; Cell Membrane; Colforsin; Conserved Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Fluorescent Antibody Technique, Indirect; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Herpesvirus 4, Human; Humans; Hydrogen Bonding; Kidney; Luciferases; Lymphocytes; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Static Electricity; Transfection

2008
Structure-Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin.
    Journal of medicinal chemistry, 2015, Nov-25, Volume: 58, Issue:22

    Topics: Alanine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Dynorphins; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Narcotic Antagonists; Peptide Fragments; Peptides; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Solubility; Stereoisomerism; Structure-Activity Relationship

2015