alanine and guanine

alanine has been researched along with guanine in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199014 (22.22)18.7374
1990's8 (12.70)18.2507
2000's14 (22.22)29.6817
2010's8 (12.70)24.3611
2020's19 (30.16)2.80

Authors

AuthorsStudies
Choe, HW; Grunert, HP; Hahn, U; Heinemann, U; Koellner, G; Saenger, W; Zouni, A1
Hakoshima, T; Ikehara, M; Kimura, T; Morioka, H; Nishikawa, S; Ohtsuka, E; Tomita, K; Uesugi, S1
Dudock, B; Michael, M; Roe, B1
Baptist, JN; Mandel, M; Seideler, RJ1
Deppe, CS; Koch, AL1
Cassone, A; Simonetti, N1
Cummins, CS; Johnson, JL1
Ninio, J1
Kallenbach, NR1
Champagne, M; Mazen, A1
Jermyn, MA1
El Sayed, YM; Nguyen, BT; Sadée, W1
Gupta, RS1
Edara, S; Goodtzova, K; Kanugula, S; Pegg, AE2
Isojima, S; Kasumi, H; Komori, S; Shima, H; Yamasaki, N1
Musier-Forsyth, K; Schimmel, P1
Arvidson, DN; Brennan, RG; Haldimann, A; Lu, F; Schumacher, MA; Wanner, BL; Zalkin, H1
German, JB; Morand, LZ; Patil, S; Quasney, M1
Bhattacharya, S; Gabriel, K; Jou, YY; McClain, WH; Schneider, J1
Al-Hendy, A; Feyles, V; Moshynska, O; Saxena, A1
Cheong, HI; Lee, YK1
Bhatt, A; Lin, B; Maddock, JR; Pawloski, L; Pfeffer, SM; Skidmore, JM1
Kierzek, AM; Kucharczyk, R; Rytka, J; Slonimski, PP1
Cordell, MR; Day, AJ; Dowling, B; Fries, E; Jenkins, SC; Loughlin, J; Mahoney, DJ; Marsden, BD; Milner, CM; Mustafa, Z; Nentwich, HA; Rugg, MS1
ADAMS, JN1
ARMSTRONG, A; HAGOPIAN, H; INGRAM, VM; SJOEQUIST, I; SJOEQUIST, J1
Connolly, SA; Francklyn, CS; Musier-Forsyth, K; Rosen, AE1
Atala, A; Bauer, SB; Deng, FM; Ehrlich, GD; Feather, SA; Gitlin, J; Goldberg, JD; Goodship, JA; Goodship, TH; Hermanns, M; Hu, FZ; Jiang, S; Jones, KE; Lee, A; Liang, FX; Malcolm, S; Mendelsohn, C; Ostrer, H; Preston, RA; Retik, AB; Schneck, FX; Shapiro, E; Sun, TT; Woolf, AS; Wright, V; Wu, XR; Ye, XY; Yu, J1
Arlt, W; Draper, N; Hartmann, MF; Stewart, PM; Wudy, SA1
Brennan, SO; Davis, RL; George, PM; Homer, VM; Meyer, M1
Christensen, E; Christensen, M; Duno, M; Lund, AM; Skovby, F1
Birkus, G; Chong, L; Cihlar, T; Desai, M; Fridland, A; Henne, IN; Jeraj, R; Lee, WA; Li, B; Liu, X; Plunkett, W; Ray, AS; Reiser, H; Rhodes, GR; Shibata, R; Thamm, DH; Tumas, DB; Vail, D; Wang, J; Watkins, WJ; Wolfgang, GH; Wu, S1
Holý, A; Otová, B; Votruba, I1
Keating, MJ; Plunkett, W; Ray, AS; Reiser, H; Tsai, CY; Tumas, DB1
Brown, M; Cooper, ME; Crout, R; DeSensi, RS; Marazita, ML; McNeil, DW; Wang, X; Wendell, S; Weyant, RJ1
Battina, SK; Bleiman, B; Bourdin, C; Brancale, A; Bryant, KD; Chamberlain, S; Ganguly, B; Gorovits, E; Henson, G; Hunley, D; Hutchins, J; Kolykhalov, A; McGuigan, C; Muhammad, J; Obikhod, A; Patti, J; Ramamurty, CV; Srivinas Rao, C; Vernachio, J; Walters, CR; Wang, J1
Babusis, D; Kurzman, ID; Ray, AS; Sousa-Powers, N; Thamm, DH; Tumas, DB; Vail, DM1
Buti, M; Esteban, R; Riveiro-Barciela, M1
Satsangi, S1
Fujii, T; Kawasoe, K; Nitta, K; Ohta, A1
Hagiwara, S; Ida, H; Komeda, Y; Kudo, M; Minami, Y; Nishida, N; Takita, M; Ueshima, K1
De Clercq, E1
Imai, Y; Kouyama, JI; Mochida, S; Motoya, D; Naiki, K; Nakao, M; Nakayama, N; Sugawara, K; Tomiya, T; Tsuji, S; Uchida, Y; Uemura, H1
Hayakawa, Y; Higuchi, M; Inada, K; Itakura, J; Izumi, N; Kaneko, S; Kirino, S; Kurosaki, M; Maeyashiki, C; Nakanishi, H; Okada, M; Osawa, L; Sekiguchi, S; Shimizu, T; Takahashi, Y; Takaura, K; Tamaki, N; Tsuchiya, K; Wang, W; Watakabe, K; Yamashita, K; Yasui, Y1
Kumada, T; Miyake, N; Tada, T; Tanaka, J; Toyoda, H; Yasuda, S1
Azuma, K; Dohmen, K; Furusyo, N; Hayashi, J; Kajiwara, E; Kato, M; Kawano, A; Koyanagi, T; Nakamuta, M; Nomura, H; Ogawa, E; Ooho, A; Satoh, T; Shimoda, S; Takahashi, K1
Kumar, M; Kumara Swamy, BE; Praveen, M; Wang, M; Zhao, W1
Fätkenheuer, G; Malin, JJ; Rybniker, J; Simonis, A; Theobald, SJ1
Wong, GL; Yip, TC1
Chen, G; Chen, SH; Fu, YM; Ji, D; Li, L; Li, ZB; Liu, Y; Niu, XX; Shao, Q; Wang, CY1
Lai, J; Li, J; Li, X; Peng, L; Shu, X; Xie, C; Xie, J; Xu, W; Zhang, Y; Zhu, X1
Jain, MK; Kshirsagar, O; Niu, B; Thamer, M; Therapondos, G; Wong, RJ1
Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC1
Chen, T; Chen, Y; Fu, M; Fu, S; Gao, Z; He, Y; Hu, C; Li, J; Liu, J; Yan, T; Yang, Y; Zhang, R; Zhao, Y; Zhou, M1
Ahn, SH; Cho, YY; Kim, BK; Kim, DY; Kim, SU; Lee, H; Lee, HW; Lee, JS; Park, JY; Park, SY1
Jeong, S; Kim, HI; Shin, HP1
Ahn, SH; Chon, HY; Kim, SU; Kim, YJ; Lee, JH; Sinn, DH; Yoon, JH1
Ito, T; Kumada, T; Tanaka, J; Toyoda, H; Yasuda, S1
Imai, Y; Kouyama, JI; Mochida, S; Naiki, K; Nakao, M; Nakayama, N; Sugawara, K; Tomiya, T; Tsuji, S; Uchida, Y; Uemura, H; Yamada, S1
Ahn, SH; Jung, CY; Kim, BS; Kim, HW; Kim, SU; Lee, HW; Lee, JI1
Akahane, T; Inoue, J; Iwata, T; Kisara, N; Kobayashi, T; Masamune, A; Ninomiya, M; Onuki, M; Sano, A; Sato, K; Sato, S; Tsuruoka, M1
Duffy, EM; Jorgensen, WL1

Reviews

4 review(s) available for alanine and guanine

ArticleYear
[Acyclic nucleoside phosphonates as potential antineoplastic agents].
    Casopis lekaru ceskych, 2008, Volume: 147, Issue:9

    Topics: Adenine; Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Guanine; Humans; Lymphoma, Non-Hodgkin; Nucleosides; Organophosphonates; Organophosphorus Compounds; Purines

2008
Long-term safety and efficacy of nucleo(t)side analogue therapy in hepatitis B.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38 Suppl 1

    Topics: Adenine; Administration, Oral; Alanine; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Randomized Controlled Trials as Topic; Tenofovir; Time Factors; Treatment Outcome

2018
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections.
    Chemistry, an Asian journal, 2019, Nov-18, Volume: 14, Issue:22

    Topics: Adenine; Adenosine; Alanine; Amides; Antiviral Agents; Base Pairing; Ebolavirus; Guanine; Hemorrhagic Fevers, Viral; Humans; Nucleotides; Phosphoric Acids; Pyrazines; Triazines

2019
A comparative analysis of remdesivir and other repurposed antivirals against SARS-CoV-2.
    EMBO molecular medicine, 2021, 01-11, Volume: 13, Issue:1

    Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Benzamidines; COVID-19 Drug Treatment; Drug Repositioning; Esters; Guanidines; Guanine; Humans; Indoles; Lopinavir; Protease Inhibitors; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Virus Internalization; Virus Replication

2021

Trials

4 trial(s) available for alanine and guanine

ArticleYear
GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.
    BMC veterinary research, 2014, Jan-25, Volume: 10

    Topics: Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Female; Guanine; Humans; Male; Multiple Myeloma; Organophosphorus Compounds; Prodrugs; Purines

2014
Switching from entecavir to tenofovir alafenamide versus maintaining entecavir for chronic hepatitis B.
    Journal of medical virology, 2019, Volume: 91, Issue:10

    Topics: Adenine; Adult; Aged; Alanine; Antiviral Agents; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Tenofovir

2019
Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B.
    BMC infectious diseases, 2021, Jun-14, Volume: 21, Issue:1

    Topics: Acute-On-Chronic Liver Failure; Adenine; Adult; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Tenofovir; Treatment Outcome

2021
Switching to tenofovir alafenamide versus continued therapy in chronic hepatitis B patients who were treated with entecavir: A prospective, multicenter, randomized controlled study.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Adenine; Alanine; Antiviral Agents; DNA, Viral; Female; Fumarates; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prospective Studies; Tenofovir; Treatment Outcome

2022

Other Studies

55 other study(ies) available for alanine and guanine

ArticleYear
His92Ala mutation in ribonuclease T1 induces segmental flexibility. An X-ray study.
    Journal of molecular biology, 1992, Apr-05, Volume: 224, Issue:3

    Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Catalysis; Cysteine; Guanine; Guanosine Monophosphate; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Ribonuclease T1; Structure-Activity Relationship; Temperature; Valine; X-Ray Diffraction

1992
Glu 46 of ribonuclease T1 is an essential residue for the recognition of guanine base.
    Biochemical and biophysical research communications, 1988, Jan-15, Volume: 150, Issue:1

    Topics: Alanine; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Endoribonucleases; Glutamine; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Mutation; Oligonucleotides; Protein Conformation; Recombinant Fusion Proteins; Ribonuclease T1; Structure-Activity Relationship; Substrate Specificity

1988
Function of N2 methylguanine in phenylalanine transfer RNA.
    Nature: New biology, 1973, Dec-05, Volume: 246, Issue:153

    Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine

1973
Molecular heterogeneity of the Bdellovibrios: evidence of two new species.
    Journal of bacteriology, 1972, Volume: 109, Issue:1

    Topics: Adenine Nucleotides; Alanine; Amino Acid Oxidoreductases; Bacteria; Bacteriological Techniques; Carbonic Anhydrases; Centrifugation, Density Gradient; Citric Acid Cycle; Culture Media; Cytosine; DNA, Bacterial; Electrophoresis; Gels; Genetics, Microbial; Glutamate Dehydrogenase; Guanine; Isocitrate Dehydrogenase; Malate Dehydrogenase; Nucleic Acid Hybridization; Nucleic Acid Renaturation; Oxidoreductases; Phosphorus Isotopes; Phosphotransferases; Quinones; RNA, Bacterial; RNA, Ribosomal; Starch; Sucrose; Terminology as Topic; Tetrazolium Salts

1972
In vivo assay of protein synthesizing capacity of Escherichia coli from slowly growing chemostat cultures.
    Journal of molecular biology, 1971, Feb-14, Volume: 55, Issue:3

    Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon; Carbon Isotopes; Escherichia coli; Glucose; Guanine; Kinetics; RNA, Bacterial; Sulfates; Tryptophan; Vitamins

1971
Inhibition of L-alanine-induced germination of Bacillus cereus spores by theophylline.
    Experientia, 1971, Volume: 27, Issue:8

    Topics: Adenine; Alanine; Bacillus cereus; Caffeine; Drug Synergism; Guanine; Hydrogen-Ion Concentration; Inosine; Spores, Bacterial; Temperature; Theophylline

1971
Cell wall composition and deoxyribonucleic acid similarities among the anaerobic coryneforms, classical propionibacteria, and strains of Arachnia propionica.
    Journal of bacteriology, 1972, Volume: 109, Issue:3

    Topics: Actinomycetales; Alanine; Anaerobiosis; Animals; Antigens, Bacterial; Base Sequence; Cell Wall; Corynebacterium; Cytosine; DNA, Bacterial; Galactose; Glucose; Glutamates; Glycine; Guanine; Mannose; Peptidoglycan; Pimelic Acids; Propionibacterium; Rabbits

1972
Codon-anticodon recognition: the missing triplet hypothesis.
    Journal of molecular biology, 1971, Feb-28, Volume: 56, Issue:1

    Topics: Alanine; Genetic Code; Guanine; Models, Chemical; Molecular Biology; Nucleosides; RNA, Transfer; Saccharomyces; Valine

1971
Theory of thermal transitions in low molecular weight RNA chains.
    Journal of molecular biology, 1968, Nov-14, Volume: 37, Issue:3

    Topics: Adenine; Alanine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Models, Structural; Molecular Weight; RNA; Thermodynamics; Tyrosine; Uracil

1968
[Fractionation of DNA on histone columns. I. Characteristic behavior of the very lysine rich histone].
    Bulletin de la Societe de chimie biologique, 1969, Jan-30, Volume: 50, Issue:10

    Topics: Alanine; Animals; Cattle; Chromatography; Cytosine; DNA; DNA, Bacterial; Erythrocytes; Guanine; Histones; Hot Temperature; Lysine; Methods; Molecular Weight; Nucleic Acid Denaturation; Nucleotides; Osmolar Concentration; Peptides; Serum Albumin; Thymus Gland; Ultrasonics

1969
Fungal cellulases. XXI. Induction of the cellulase of Stachybotrys atra.
    Australian journal of biological sciences, 1967, Volume: 20, Issue:1

    Topics: Alanine; Antimetabolites; Arsenicals; Azaguanine; Azides; Cellulose; Enzyme Induction; Fluorides; Glucose; Glycerol; Glycoside Hydrolases; Guanine; Mitosporic Fungi; Phenylalanine; Sucrose; Xylose

1967
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replication; Guanine; Kinetics; Lymphoma; Methylthioinosine; Mice; Mycophenolic Acid

1984
A novel synergistic effect of alanosine and guanine on adenine nucleotide synthesis in mammalian cells. Alanosine as a useful probe for investigating purine nucleotide metabolism.
    Journal of cellular physiology, 1980, Volume: 104, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenylosuccinate Synthase; Alanine; Animals; Cell Division; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanine; Humans; Nitrosamines; Ovary; Purine Nucleotides

1980
Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine.
    Biochemistry, 1995, May-30, Volume: 34, Issue:21

    Topics: Alanine; Animals; Arginine; Base Sequence; Cattle; DNA; DNA Repair; DNA-Binding Proteins; Guanine; Humans; Methylation; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase

1995
Single nucleotide substitution of the androgen receptor gene in a case with receptor-positive androgen insensitivity syndrome (complete form).
    Acta endocrinologica, 1993, Volume: 128, Issue:4

    Topics: Adult; Alanine; Amino Acid Sequence; Androgen-Insensitivity Syndrome; Base Sequence; Cells, Cultured; Cytosine; Dihydrotestosterone; DNA; Exons; Glycine; Guanine; Hot Temperature; Humans; Male; Molecular Sequence Data; Oligonucleotide Probes; Point Mutation; Polymerase Chain Reaction; Receptors, Androgen; Sequence Homology, Amino Acid; Sex Chromosome Aberrations

1993
'Distorted' RNA helix recognition.
    Nature, 1996, Dec-05, Volume: 384, Issue:6608

    Topics: Alanine; Base Composition; Genetic Code; Glutamate-tRNA Ligase; Guanine; Models, Genetic; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; RNA; RNA, Transfer; Uridine

1996
Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
    Biochemistry, 1998, Jan-27, Volume: 37, Issue:4

    Topics: Adenine; Alanine; Arginine; Bacterial Proteins; Crystallography, X-Ray; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamine; Guanine; Hypoxanthine; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Purines; Repressor Proteins

1998
Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis.
    Biochemical and biophysical research communications, 1998, Mar-06, Volume: 244, Issue:1

    Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferases; Adenine; Alanine; Amino Acid Substitution; Bacterial Proteins; Binding, Competitive; Dyneins; Escherichia coli; Escherichia coli Proteins; Fatty Acids; Fungal Proteins; Guanine; Leucine; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Temperature; Threonine; Transformation, Bacterial

1998
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
    Biochemistry, 1998, Sep-08, Volume: 37, Issue:36

    Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine

1998
Functional compensation by particular nucleotide substitutions of a critical G*U wobble base-pair during aminoacylation of transfer RNA.
    Journal of molecular biology, 1999, Mar-05, Volume: 286, Issue:4

    Topics: Acylation; Alanine; Amino Acyl-tRNA Synthetases; Base Pairing; Base Sequence; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Point Mutation; RNA, Transfer, Amino Acyl; Uridine

1999
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
    Lancet (London, England), 2000, Sep-09, Volume: 356, Issue:9233

    Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic

2000
A novel polymorphism (g722G>A) in exon 2 of the AVPR2 gene.
    Human mutation, 2000, Volume: 16, Issue:5

    Topics: Adenine; Alanine; Diabetes Insipidus, Nephrogenic; Exons; Guanine; Humans; Polymorphism, Genetic; Receptors, Vasopressin; X Chromosome

2000
Alanine scan mutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals critical amino acids required for in vivo function.
    Molecular microbiology, 2001, Volume: 39, Issue:4

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Caulobacter crescentus; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; Xylose

2001
The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 17

    Topics: Alanine; Alleles; Amino Acid Sequence; Aspartic Acid; Biological Transport; Caffeine; Calcium; Carrier Proteins; Central Nervous System Stimulants; DNA; Epitopes; Gene Deletion; Gene Library; Genetic Complementation Test; Guanine; Guanine Nucleotide Exchange Factors; Hemagglutinins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenotype; Polymerase Chain Reaction; Precipitin Tests; Protein Binding; rab GTP-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Vacuoles; Vesicular Transport Proteins; Zinc

2001
A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Adenine; Alanine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Cell Adhesion Molecules; Chromosome Mapping; Chromosomes, Human, Pair 2; Gene Frequency; Genetic Linkage; Genetic Variation; Glutamine; Guanine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Osteoarthritis; Polymorphism, Single Nucleotide; Protein Conformation; Tumor Necrosis Factor-alpha

2002
RECOMBINATION BETWEEN NOCARDIA ERYTHROPOLIS AND NOCARDIA CANICRURIA.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Adenine; Alanine; Anti-Bacterial Agents; Arginine; Cysteine; Cystine; Drug Resistance; Drug Resistance, Microbial; Glycine; Guanine; Histidine; Hypoxanthines; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Mutation; Nocardia; Recombination, Genetic; Research; Streptomycin; Valine; Xanthines

1964
CHEMICAL STUDIES ON AMINO ACID ACCEPTOR RIBONUCLEIC ACIDS. 3. THE DEGRADATION OF PURIFIED ALANINE- AND VALINE-SPECIFIC YEAST S-RNA'S BY PANCREATIC RIBONUCLEASE.
    Biochemistry, 1964, Volume: 3

    Topics: Alanine; Amino Acids; Chromatography; Cytosine; Guanine; Hypoxanthines; Nucleosides; Nucleotides; Pancreas; Research; Ribonuclease, Pancreatic; Ribonucleases; RNA; Thymine; Uracil Nucleotides; Valine; Yeasts

1964
G-1:C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Acylation; Alanine; Arginine; Base Pairing; Binding Sites; Computer Simulation; Cytosine; Escherichia coli Proteins; Guanine; Histidine; Histidine-tRNA Ligase; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pyridoxal Phosphate; RNA, Transfer, His; Substrate Specificity

2004
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
    Kidney international, 2004, Volume: 66, Issue:1

    Topics: Alanine; Amino Acid Substitution; Animals; Base Sequence; Case-Control Studies; Chromosome Mapping; Cytosine; Embryo, Mammalian; Exons; Gene Expression; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Introns; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proline; Thymine; Uroplakin Ia; Uroplakin Ib; Uroplakin II; Uroplakin III; Urothelium; Vesico-Ureteral Reflux

2004
A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency.
    Endocrine research, 2004, Volume: 30, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Abnormalities, Multiple; Alanine; Amino Acid Substitution; Cytosine; Diagnosis, Differential; Diseases in Twins; Ear; Female; Guanine; Humans; Infant, Newborn; Male; Marfan Syndrome; NADPH-Ferrihemoprotein Reductase; Proline; Skull; Steroid Metabolism, Inborn Errors; Steroids

2004
Hypofibrinogenaemia associated with common gamma82Ala-->Gly mutation is not mediated by altered mRNA splicing.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:4

    Topics: Afibrinogenemia; Alanine; Animals; Chlorocebus aethiops; COS Cells; Cytosine; Fibrinogen; Glycine; Guanine; Humans; Mutation; Protein Conformation; RNA Splicing; RNA, Messenger; Sequence Analysis, DNA; Transfection

2006
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase.
    Journal of inherited metabolic disease, 2007, Volume: 30, Issue:2

    Topics: Adenine; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Substitution; Child; DNA Mutational Analysis; Genotype; Guanine; Homozygote; Humans; Hydrolases; Male; Mutation; Pedigree; Threonine; Xanthurenates

2007
GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, May-01, Volume: 14, Issue:9

    Topics: Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dogs; Guanine; Lymphoid Tissue; Lymphoma, Non-Hodgkin; Organophosphorus Compounds; Prodrugs; Purines; Tissue Distribution

2008
Targeting DNA repair in chronic lymphocytic leukemia cells with a novel acyclic nucleotide analogue, GS-9219.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11

    Topics: Alanine; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Survival; Chromatography, High Pressure Liquid; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Guanine; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Biological; Molecular Structure; Organophosphorus Compounds; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Purines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Cells, Cultured; Ultraviolet Rays

2009
Taste genes associated with dental caries.
    Journal of dental research, 2010, Volume: 89, Issue:11

    Topics: Adenine; Adult; Alanine; Child; Child, Preschool; Cohort Studies; Cytosine; Dental Caries; Dental Caries Susceptibility; DMF Index; Female; Gene Frequency; Genetic Variation; Genotype; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Proline; Receptors, G-Protein-Coupled; Risk Factors; Taste; Thymine; Transducin; Valine

2010
Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.
    Bioorganic & medicinal chemistry letters, 2013, Apr-01, Volume: 23, Issue:7

    Topics: Alanine; Amides; Antiviral Agents; Esters; Guanine; Hepacivirus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Phosphoric Acids

2013
To use entecavir, tenofovir disoproxil fumarate or tenofovir alafenamide: it's all about choosing the right patient!
    European journal of gastroenterology & hepatology, 2018, Volume: 30, Issue:6

    Topics: Adenine; Alanine; Anti-HIV Agents; Guanine; HIV Infections; Humans; Tenofovir

2018
A case of entecavir-induced Fanconi syndrome.
    CEN case reports, 2019, Volume: 8, Issue:4

    Topics: Acidosis; Acute Kidney Injury; Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Guanine; Hepatitis B, Chronic; Humans; Hypokalemia; Hypophosphatemia; Male; Nucleosides; Tenofovir; Treatment Outcome; Withholding Treatment

2019
Significance of switching of the nucleos(t)ide analog used to treat Japanese patients with chronic hepatitis B virus infection from entecavir to tenofovir alafenamide fumarate.
    Journal of medical virology, 2020, Volume: 92, Issue:3

    Topics: Adenine; Aged; Alanine; Antibodies, Viral; Antiviral Agents; Female; Fumarates; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Japan; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Surveys and Questionnaires; Tenofovir; Transaminases; Treatment Outcome

2020
Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:9

    Topics: Adenine; Adult; Alanine; Antiviral Agents; Asian People; Carcinoma, Hepatocellular; Cohort Studies; Female; Guanine; Hepatitis B, Chronic; Humans; Japan; Liver Neoplasms; Male; Middle Aged; Nucleotides; Platelet Count; Research Design; Risk; Tenofovir; Time Factors

2020
Comparison of the impact of tenofovir alafenamide and entecavir on declines of hepatitis B surface antigen levels.
    European journal of gastroenterology & hepatology, 2021, 02-01, Volume: 32, Issue:2

    Topics: Alanine; Antiviral Agents; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Tenofovir; Treatment Outcome

2021
Tenofovir alafenamide after switching from entecavir or nucleos(t)ide combination therapy for patients with chronic hepatitis B.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:7

    Topics: Adenine; Alanine; Antiviral Agents; Cohort Studies; Guanine; Hepatitis B, Chronic; Humans; Retrospective Studies; Tenofovir; Treatment Outcome

2020
Poly (alanine)/NaOH/ MoS
    Colloids and surfaces. B, Biointerfaces, 2020, Volume: 196

    Topics: Alanine; Ascorbic Acid; Biosensing Techniques; Carbon; Dopamine; Electrodes; Guanine; Humans; Molybdenum; Serotonin; Sodium Hydroxide

2020
HCC risk reduction with oral nucleos(t)ide analogues in patients with chronic hepatitis B: Not perfect, not good enough.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:10

    Topics: Adenine; Administration, Oral; Alanine; Carcinoma, Hepatocellular; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Nucleotides; Tenofovir

2020
Switching from entecavir to tenofovir alafenamide for chronic hepatitis B patients with low-level viraemia.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:6

    Topics: Adenine; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Prospective Studies; Tenofovir; Treatment Outcome; Viremia

2021
The 48-week safety and therapeutic effects of tenofovir alafenamide in hbv-related acute-on-chronic liver failure: A prospective cohort study.
    Journal of viral hepatitis, 2021, Volume: 28, Issue:4

    Topics: Acute-On-Chronic Liver Failure; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Prospective Studies; Tenofovir; Treatment Outcome

2021
Antiviral Therapy Reduces Risk of Cirrhosis in Noncirrhotic HBV Patients Among 4 Urban Safety-Net Health Systems.
    The American journal of gastroenterology, 2021, 07-01, Volume: 116, Issue:7

    Topics: Adult; Aged; Alanine; Antiviral Agents; Asian; Black or African American; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mortality; Propensity Score; Proportional Hazards Models; Retrospective Studies; Safety-net Providers; Tenofovir; United States; Urban Population; White People

2021
Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog.
    Clinical and translational gastroenterology, 2021, 03-23, Volume: 12, Issue:3

    Topics: Adult; Aged; Alanine; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Guanine; Hepatitis B, Chronic; Hong Kong; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Tenofovir

2021
Impact of tenofovir alafenamide vs. entecavir on hepatocellular carcinoma risk in patients with chronic hepatitis B.
    Hepatology international, 2021, Volume: 15, Issue:5

    Topics: Alanine; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Retrospective Studies; Tenofovir; Treatment Outcome

2021
Real-World Single-Center Comparison of the Safety and Efficacy of Entecavir, Tenofovir Disoproxil Fumarate, and Tenofovir Alafenamide in Patients with Chronic Hepatitis B.
    Intervirology, 2022, Volume: 65, Issue:2

    Topics: Alanine; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Tenofovir; Treatment Outcome

2022
Efficacy of entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide in treatment-naive hepatitis B patients.
    Hepatology international, 2021, Volume: 15, Issue:6

    Topics: Aged; Alanine; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Tenofovir; Treatment Outcome

2021
Impact of switching to tenofovir alafenamide fumarate in patients with entecavir-treated chronic hepatitis B.
    European journal of gastroenterology & hepatology, 2021, 12-01, Volume: 33, Issue:1S Suppl 1

    Topics: Adenine; Alanine; Antiviral Agents; Fumarates; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Retrospective Studies; Tenofovir; Treatment Outcome

2021
Superiority of tenofovir alafenamide fumarate over entecavir for serum HBsAg level reduction in patients with chronic HBV infection: A 144-week outcome study after switching of the nucleos(t)ide analog.
    PloS one, 2022, Volume: 17, Issue:2

    Topics: Aged; Alanine; Antiviral Agents; Drug Substitution; Female; Follow-Up Studies; Fumarates; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Prospective Studies; Tenofovir; Treatment Outcome

2022
Similar risk of kidney function decline between tenofovir alafenamide and besifovir dipivoxil maleate in chronic hepatitis B.
    Liver international : official journal of the International Association for the Study of the Liver, 2022, Volume: 42, Issue:11

    Topics: Adenine; Alanine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Kidney; Longitudinal Studies; Maleates; Organophosphonates; Renal Insufficiency, Chronic; Retrospective Studies; Tenofovir; Treatment Outcome

2022
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000