alanine and fibrinogen

alanine has been researched along with fibrinogen in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (45.00)	18.7374
1990's	6 (10.00)	18.2507
2000's	23 (38.33)	29.6817
2010's	3 (5.00)	24.3611
2020's	1 (1.67)	2.80

Authors

Authors	Studies
Harris, JU; Johnson, AJ; Merskey, C; Robinson, D; Wang, MT	1
Alberti, KG; Betteridge, DJ; Cudworth, AG; De Silva, SR; Shawe, JE	1
Boni, P; Culasso, D; Musumeci, V	1
Hoffman, AS; Horbett, TA; Weathersby, PK	1
Kemler, V; Pilgeram, LO; von dem Bussche, G	1
Aruga, R; Bezeaud, A; Guillin, MC; Iwanaga, S; Miyata, T; Umeyama, H	1
Botstein, D; Brady, K; Johnson, AC; Kerr, EM; Nguyen, HV; Paoni, NF; Peña, LC; Refino, CJ; van Reis, R; Wurm, FM	1
Hasegawa, N; Sasaki, S	1
Agam, G; Dvilansky, A; Livne, A; Luria, R; Seligsohn, U; Shohat, O	1
Maurer, PH; Merryman, CF; Stylos, WA	1
Graeff, H; von Hugo, R	2
Arnesen, H; Kierulf, P; Ly, B	1
Straughn, W; Wagner, RH	1
Hörmann, H; Jilg, W	1
Kierulf, P	2
Murray, M; Rearick, DE	1
Murray, M; Smith, GF	1
Godal, HC; Kierulf, P	1
Iwanaga, S; Okude, M	1
Cartwright, T; Kekwick, RG	1
Blombäck, B	1
Abildgaard, U	2
Corcoran, DH; Ferguson, EW; Fretto, LJ; McKee, PA	1
McGuinness, OP	1
Burrin, DG; Frazer, M; Jahoor, F; Reeds, PJ	1
Bron, N; Gouon, V; Guinet, JM; Kieffer, N; Melchior, C; Michels, S	1
Baruch, D; Kieffer, N; Mekrache, M; Melchior, C; Perrault, C; Schoevaert, D; Warszawski, J	1
Schneider, DJ; Sobel, BE; Taatjes, DJ	1
Cannon, CP; Holmes, MB; Schneider, DJ; Sobel, BE	1
Gorkun, OV; Lord, ST; Mullin, JL	1
Bozarth, JM; Forsythe, MS; Mousa, SA; Slee, A	1
Bozarth, J; Confalone, PN; Forsythe, M; Jin, F; Mousa, SA	1
Foster, TJ; McAleese, FM; Potempa, J; Sieprawska, M; Walsh, EJ	1
Kilian, M; Kosowska, K; Potempa, J; Poulsen, K; Rasmussen, LK; Reinholdt, J; Sabat, A	1
Gorkun, OV; Lord, ST; Lounes, KC; Ping, L	1
Bodnar, RJ; Du, X; Lam, SC; Li, Z; Xi, X	1
Haas, TA; Lishko, VK; Lord, ST; Merkulov, SM; Okumura, N; Podolnikova, NP; Ugarova, TP; Yakubenko, VP; Yee, VC	1
JAYLE, MF; MORETTI, J; MOURAY, H	1
BLOUT, ER; SHECHTER, E	1
BRINKHOUS, KM; MCLESTER, WD; SMITH, M; WAGNER, BH	1
Bowden, MG; Choe, D; Davis, S; Gurusiddappa, S; Hook, M; Moore, D; Narayana, SV; Ponnuraj, K; Xu, Y	1
Fujita, S; Hato, T; Tamura, T; Yamanouchi, J	1
Betts, L; Bolliger-Stucki, B; Gorkun, OV; Kostelansky, MS; Lord, ST	1
Artoni, A; Coller, BS; Filizola, M; Hassan, SA; Weinstein, H	1
Blanquart, C; Fruchart, JC; Glineur, C; Mansouri, R; Paumelle, R; Staels, B	1
Hirota-Kawadobora, M; Okumura, N; Sano, K; Suzuki, T; Terasawa, F; Tozuka, M	1
Brennan, SO; Dear, A; Dempfle, CE; George, PM; Kirschstein, W	1
Fujihara, N; Hirota-Kawadobora, M; Kani, S; Okumura, N; Terasawa, F; Tozuka, M; Yamauchi, K	1
George, NP; Konstantopoulos, K; Ross, JM; Shin, PK; Wei, Q	1
Brennan, SO; Davis, RL; George, PM; Homer, VM; Meyer, M	1
Connor, JH; Connor, RF; Hantgan, RR; Mousa, SA; Stahle, MC	1
Brennan, SO; Dietzel, H; Kaetzel, R; Liebscher, K; Meyer, M; Schmidt, D	1
Algra, A; Garcia, AA; Gorter, JW; Kappelle, LJ; Pruissen, DM; Rosendaal, FR	1
Di Cera, E; Gandhi, PS; Marino, F; Pelc, LA; Vogt, A	1
Antoniades, C; Kardara, D; Koumallos, N; Kyvelou, SM; Papageorgiou, N; Stefanadis, C; Tousoulis, D; Vasiliadou, C; Vlachopoulos, C; Xaplanteris, P	1
Choi, JR; Choi, TY; Gorkun, OV; Hong, SY; Lord, ST; Park, R; Ping, L; Song, J	1
Bock, PE; Maddur, AA; Meiler, J; Panizzi, P; Verhamme, IM; Voehler, M	1

Trials

2 trial(s) available for alanine and fibrinogen

Article	Year
Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment. Diabete & metabolisme, 1979, Volume: 5, Issue:3 Topics: Alanine; Blood Glucose; Cholesterol; Circadian Rhythm; Clofibrate; Diabetes Mellitus; Drug Synergism; Fibrinogen; Glycerol; Humans; Hydroxybutyrates; Lactates; Lipoproteins; Metformin; Triglycerides	1979
Increased platelet reactivity in patients given orbofiban after an acute coronary syndrome: an OPUS-TIMI 16 substudy. Orbofiban in Patients with Unstable coronary syndromes. Thrombolysis In Myocardial Infarction. The American journal of cardiology, 2000, Feb-15, Volume: 85, Issue:4 Topics: Acute Disease; Administration, Oral; Alanine; Blood Platelets; Coronary Thrombosis; Fibrinogen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Recurrence; Thrombolytic Therapy; Treatment Outcome	2000

Article

Year

Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment.

Diabete & metabolisme, 1979, Volume: 5, Issue:3

Topics: Alanine; Blood Glucose; Cholesterol; Circadian Rhythm; Clofibrate; Diabetes Mellitus; Drug Synergism; Fibrinogen; Glycerol; Humans; Hydroxybutyrates; Lactates; Lipoproteins; Metformin; Triglycerides

1979

Increased platelet reactivity in patients given orbofiban after an acute coronary syndrome: an OPUS-TIMI 16 substudy. Orbofiban in Patients with Unstable coronary syndromes. Thrombolysis In Myocardial Infarction.

The American journal of cardiology, 2000, Feb-15, Volume: 85, Issue:4

Topics: Acute Disease; Administration, Oral; Alanine; Blood Platelets; Coronary Thrombosis; Fibrinogen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Recurrence; Thrombolytic Therapy; Treatment Outcome

2000

Other Studies

58 other study(ies) available for alanine and fibrinogen

Article	Year
Quantitative N-terminal analysis of fibrinogen-fibrin-related antigen [FR antigen] from human plasma. The Biochemical journal, 1979, Dec-01, Volume: 183, Issue:3 Topics: Alanine; Amino Acid Sequence; Antigens; Disseminated Intravascular Coagulation; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Pulmonary Embolism; Thrombin; Urokinase-Type Plasminogen Activator	1979
A rapid chromatographic method for quantitation of high molecular weight fibrinogen derivatives in plasma. Thrombosis and haemostasis, 1978, Jun-30, Volume: 39, Issue:3 Topics: Alanine; Ammonium Sulfate; Chemical Precipitation; Chromatography, Gel; Fibrinogen; Humans; Molecular Weight	1978
Solution stability of bovine fibrinogen. Thrombosis research, 1977, Volume: 10, Issue:2 Topics: Alanine; Animals; Cattle; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Methods; Molecular Weight; Polyethylene Glycols; Trichloroacetic Acid	1977
Estrogen induced appearance of N-terminal glycine from chromatographically purified fibrinogen. Thrombosis research, 1975, Volume: 6, Issue:2 Topics: Alanine; Chromatography, Thin Layer; Estrogens; Fibrinogen; Glycine; Humans; Tyrosine	1975
Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity. Biochemistry, 1992, Aug-25, Volume: 31, Issue:33 Topics: Alanine; Amino Acid Sequence; Base Sequence; Codon; Esterases; Fibrinogen; Glutamates; Glutamic Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Protein Conformation; Prothrombin	1992
Involvement of residues 296-299 in the enzymatic activity of tissue-type plasminogen activator. Protein engineering, 1992, Volume: 5, Issue:3 Topics: Alanine; Amino Acid Sequence; Fibrin; Fibrinogen; Fibrinolysis; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Plasma; Plasminogen; Protein Engineering; Tissue Plasminogen Activator	1992
A deficiency in A alpha chain's N-terminal alanine residue as a major cause of the slow coagulation of fetal fibrinogen. Thrombosis research, 1989, Jun-15, Volume: 54, Issue:6 Topics: Alanine; Amino Acids; Aminopeptidases; Blood Coagulation Disorders; CD13 Antigens; Electrophoresis, Polyacrylamide Gel; Fetal Blood; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glycine; Humans; Infant, Newborn; Thrombin Time	1989
Lysine binding to activated human platelets and its similarity to fibrinogen binding. Biochimica et biophysica acta, 1985, Dec-12, Volume: 847, Issue:3 Topics: Alanine; Amines; Blood Platelets; Calcimycin; Fibrinogen; Glycoproteins; Humans; Lysine; Membrane Proteins; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombasthenia	1985
Antigenicity of polypeptides (poly-alpha-amino acids). Distribution of sheep antibodies to dinitrinophenyl-(DNP) conjugates of polymers of alpha-L-amino acids of varying electrical charge. International archives of allergy and applied immunology, 1970, Volume: 39, Issue:4 Topics: Alanine; Amino Acids; Animals; Antibodies; Antibody-Producing Cells; Antigens; Clone Cells; Dinitrophenols; Fibrinogen; gamma-Globulins; Glutamine; Haptens; Immunoelectrophoresis; Immunoglobulins; Lysine; Peptides; Polymers; Precipitin Tests; Precipitins; Protein Binding; Sheep	1970
[Identification and preparation of high-molecular derivatives of fibrinogen from human plasma by means of PAA-gel electrophoresis and agarose-gel chromatography]. Thrombosis et diathesis haemorrhagica. Supplementum, 1973, Volume: 55 Topics: Alanine; Blood Coagulation Tests; Chromatography; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Humans; Immunodiffusion; Methods; Molecular Weight; Polysaccharides; Urea	1973
Molecular aspects of the clottable proteins of human plasma during fibrinogenolysis. Thrombosis research, 1974, Volume: 5, Issue:3 Topics: Alanine; Blood Coagulation; Blood Coagulation Tests; Blood Protein Electrophoresis; Blood Proteins; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Glycine; Humans; Molecular Weight; Tyrosine; Urokinase-Type Plasminogen Activator	1974
A simple method for preparing fibrinogen. Thrombosis et diathesis haemorrhagica, 1966, Jul-31, Volume: 16, Issue:1 Topics: Alanine; Aminobutyrates; Aminocaproates; Animals; Blood Coagulation; Blood Proteins; Cattle; Chemical Precipitation; Chromatography, Gel; Dogs; Factor VIII; Fibrinogen; Fibrinolysin; Humans; Methods; Plasminogen; Swine	1966
Fibrinogen of relatively high solubility, III. Residual clottable material in plasma deprived of the majority of fibrinogen. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1974, Volume: 355, Issue:10 Topics: Alanine; Blood Coagulation; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinolysis; Humans; Molecular Weight; Protein Conformation; Sodium Dodecyl Sulfate; Solubility; Ultracentrifugation	1974
Studies on soluble fibrin in plasma. 3. N-terminal analysis of a modified fraction I (Cohn) from plasmin- and thrombin-incubated plasma. Scandinavian journal of clinical and laboratory investigation, 1973, Volume: 31, Issue:1 Topics: Alanine; Aspartic Acid; Autoanalysis; Blood Coagulation; Blood Proteins; Buffers; Fibrin; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Glutamates; Glycine; Humans; Methods; Solubility; Thrombin; Tyrosine	1973
Fibrin-I degradation products with a molecular weight higher than that of fibrinogen. Identification and characterization of in vitro products from human plasma. Thrombosis et diathesis haemorrhagica, 1973, Feb-28, Volume: 29, Issue:1 Topics: Alanine; Blood Protein Electrophoresis; Chemical Precipitation; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Humans; Molecular Weight; Streptokinase	1973
Interaction between red cell membranes and fibrinogen. Thrombosis research, 1974, Volume: 4, Issue:2 Topics: Alanine; Amino Acids; Aspartic Acid; Blood Coagulation Tests; Cell Membrane; Erythrocytes; Fibrin; Fibrinogen; Glycine; Humans; Protein Conformation; Tyrosine	1974
Thrombosis and blood coagulation. A study by quantitative N-terminal amino acid analysis. Archives of pathology, 1970, Volume: 89, Issue:3 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Binding Sites; Blood Coagulation; Cattle; Chemical Phenomena; Chemistry; Edetic Acid; Fibrin; Fibrinogen; Glycine; Humans; Immunoelectrophoresis; Models, Biological; Thrombin; Thrombosis; Tyrosine	1970
Studies on soluble fibrin in plasma. I a. N-terminal analysis of a modified fraction I (Cohn) from plasma containing fibrinolytic inhibitors, and incubated with plasminogen-free human thrombin. Scandinavian journal of clinical and laboratory investigation, 1972, Volume: 29, Issue:3 Topics: Alanine; Antifibrinolytic Agents; Aspartic Acid; Blood Coagulation; Blood Proteins; Chemical Precipitation; Ethanol; Fibrin; Fibrinogen; Glutamine; Glycine; Humans; In Vitro Techniques; Plasma; Thrombin; Tyrosine	1972
Fibrinaemia and multiple thrombi in pancreatic carcinoma. A case studied with quantitative N-terminal analysis. Scandinavian journal of haematology, 1972, Volume: 9, Issue:4 Topics: Alanine; Blood Coagulation; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Fibrin; Fibrinogen; Glycine; Heparin; Humans; Male; Methods; Middle Aged; Pancreatic Neoplasms; Thrombin; Thrombophlebitis; Tyrosine; Warfarin	1972
Carboxyl-terminal residues of fibrinogen and fibrin. Biochemical and biophysical research communications, 1970, Oct-23, Volume: 41, Issue:2 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Fibrin; Fibrinogen; Hydrazines; Pancreas; Peptides; Proline; Protein Denaturation; Ribonucleases; Time Factors; Tritium; Valine	1970
A comparative study of human, cow, pig and sheep fibrinogen. Biochimica et biophysica acta, 1971, Jun-29, Volume: 236, Issue:3 Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Fibrinogen; Glutamates; Humans; Macromolecular Substances; Paper; Peptides; Sheep; Species Specificity; Sulfites; Swine; Thrombin; Trypsin; Tyrosine	1971
The N-terminal disulphide knot of human fibrinogen. British journal of haematology, 1969, Volume: 17, Issue:2 Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography; Cyanides; Electrophoresis; Fibrinogen; Humans; Methionine; Peptides; Sulfides	1969
N-terminal analysis during coagulation of purified human fibrinogen, fraction I, and plasma. Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17, Issue:6 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood; Blood Proteins; Cattle; Chemistry Techniques, Analytical; Fibrinogen; Glutamine; Glycine; Humans; In Vitro Techniques; Peptides; Plasma; Thrombin; Tyrosine; Valine	1965
Acceleration of fibrin polymerization by dextran and ficoll. Interaction with calcium and plasma proteins. Scandinavian journal of clinical and laboratory investigation, 1966, Volume: 18, Issue:5 Topics: Alanine; Animals; Blood Coagulation; Blood Proteins; Calcium; Cattle; Chemical Phenomena; Chemistry; Dextrans; Fibrin; Fibrinogen; Glycine; Humans; Polysaccharides; Thrombin	1966
Localization of a cross-link donor site in the alpha-chain of human fibrin. Thrombosis research, 1980, Sep-15, Volume: 19, Issue:6 Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Fibrin; Fibrinogen; Lysine; Peptides; Threonine; Valine	1980
The impact of infection on gluconeogenesis in the conscious dog. Shock (Augusta, Ga.), 1994, Volume: 2, Issue:5 Topics: Alanine; Animals; Carbon Radioisotopes; Cattle; Dogs; Escherichia coli Infections; Fibrinogen; Glucagon; Gluconeogenesis; Glucose; Glycerol; Hydrocortisone; Insulin; Lactates; Lactic Acid; Liver; Radioisotope Dilution Technique; Reference Values; Tritium	1994
Measurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches. The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2 Topics: Alanine; Animals; Animals, Newborn; Apolipoprotein B-100; Apolipoproteins B; Blood Proteins; Carbon Isotopes; Deuterium; Female; Fibrinogen; Leucine; Liver; Lysine; Male; Serum Albumin; Swine	1994
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events. Cell adhesion and communication, 1996, Volume: 4, Issue:1 Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Extracellular Matrix Proteins; Fibrinogen; Genetic Complementation Test; Humans; Integrin beta3; Molecular Sequence Data; Oligopeptides; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Proline; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Sequence Alignment; Serine; Signal Transduction; Thrombasthenia; Transfection; Vitronectin; von Willebrand Factor	1996
Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen. Cell adhesion and communication, 1998, Volume: 6, Issue:4 Topics: Alanine; Animals; Antigens, CD; Cell Adhesion; Cell Count; Cell Line; Cricetinae; Cytoskeleton; Fibrinogen; Humans; Image Processing, Computer-Assisted; Integrin beta3; Kinetics; Platelet Membrane Glycoproteins; Point Mutation; Proline; Serine; von Willebrand Factor	1998
Paradoxical inhibition of fibrinogen binding and potentiation of alpha-granule release by specific types of inhibitors of glycoprotein IIb-IIIa. Cardiovascular research, 2000, Jan-14, Volume: 45, Issue:2 Topics: Abciximab; Alanine; Antibodies, Monoclonal; Antigens, CD; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Flow Cytometry; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Microscopy, Confocal; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein Binding; Pyrrolidines; Tetraspanin 30	2000
Decreased lateral aggregation of a variant recombinant fibrinogen provides insight into the polymerization mechanism. Biochemistry, 2000, Aug-15, Volume: 39, Issue:32 Topics: Alanine; Ancrod; Blood Coagulation; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Genetic Variation; Polymers; Recombinant Proteins; Threonine; Thrombin	2000
Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels. Cardiovascular research, 2000, Volume: 47, Issue:4 Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Calcium; Citric Acid; Eptifibatide; Fibrinogen; Heparin; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Isoxazoles; Peptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Tirofiban; Tyrosine	2000
Human platelet alphaIIbeta3 integrin binding affinity and specificity of SJ874: antiplatelet efficacy versus aspirin. Coronary artery disease, 2000, Volume: 11, Issue:7 Topics: Alanine; Aspirin; Bacterial Proteins; Blood Platelets; Cell Adhesion; Cell Line; DNA-Binding Proteins; Epinephrine; Fibrinogen; Fibronectins; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex	2000
Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease. The Journal of biological chemistry, 2001, Aug-10, Volume: 276, Issue:32 Topics: Adhesins, Bacterial; Alanine; beta-Galactosidase; Binding Sites; Blotting, Southern; Blotting, Western; Coagulase; Dose-Response Relationship, Drug; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Genes, Reporter; Genotype; Leucine; Metalloendopeptidases; Mutagenesis, Site-Directed; Mutation; Phenanthrolines; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Staphylococcus aureus; Time Factors; Transcription, Genetic; Valine	2001
The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase. The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Blotting, Southern; Catalysis; Cell Wall; Clostridium; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Evolution, Molecular; Fibrinogen; Gelatin; Humans; Immunoglobulin A; Metalloendopeptidases; Molecular Sequence Data; Muramidase; Mutagenesis, Site-Directed; Open Reading Frames; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Serine Endopeptidases; Time Factors; Zinc	2002
Analysis of engineered fibrinogen variants suggests that an additional site mediates platelet aggregation and that "B-b" interactions have a role in protofibril formation. Biochemistry, 2002, Apr-23, Volume: 41, Issue:16 Topics: Alanine; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Aspartic Acid; Binding Sites, Antibody; CHO Cells; Chromatography, Gel; Cricetinae; Fibrinogen; Fibrinolysin; Fibrinopeptide A; Fibrinopeptide B; Genetic Variation; Humans; Mutagenesis, Site-Directed; Nephelometry and Turbidimetry; Platelet Aggregation; Polymers; Recombinant Proteins	2002
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling. The Journal of cell biology, 2003, Jul-21, Volume: 162, Issue:2 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Calpain; Cell Adhesion; Cell Line; CHO Cells; Cricetinae; Cytoplasm; Fibrinogen; Humans; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Signal Transduction; Thrombin; von Willebrand Factor	2003
Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen. Biochemistry, 2003, Aug-12, Volume: 42, Issue:31 Topics: Alanine; Binding Sites; Cell Adhesion; Cell Line; Fibrinogen; Humans; Leukocytes; Ligands; Macrophage-1 Antigen; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptide Fragments; Peptides, Cyclic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Deletion	2003
[INCORPORATION IN VIVO OF LABELED AMINO ACIDS INTO RABBIT PLASMA PROTEINS]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, May-11, Volume: 258 Topics: Alanine; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Fibrinogen; Granuloma; Haptoglobins; Leucine; Rabbits; Radiometry; Research; Toxicology; Tritium; Turpentine; Valine	1964
AN ANALYSIS OF THE OPTICAL ROTATORY DISPERSION OF POLYPEPTIDES AND PROTEINS. Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51 Topics: Alanine; Animals; Cattle; Chemical Phenomena; Chemistry; Fibrinogen; Globulins; Glutamates; Lysine; Muscle Proteins; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Research; Ribonucleases; Serine; Serum Albumin; Serum Albumin, Bovine	1964
PURIFICATION OF ANTIHEMOPHILIC FACTOR (FACTOR VIII) BY AMINO ACID PRECIPITATION. Thrombosis et diathesis haemorrhagica, 1964, Apr-15, Volume: 11 Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Blood Coagulation Tests; Blood Proteins; Chemical Phenomena; Chemistry; Dogs; Factor VIII; Fibrinogen; Glycine; Research	1964
A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen. Cell, 2003, Oct-17, Volume: 115, Issue:2 Topics: Adhesins, Bacterial; Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Bacterial Adhesion; Bacterial Proteins; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Fibrinogen; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Structure, Tertiary; Serine; Staphylococcus epidermidis; Thrombin	2003
Critical residues for ligand binding in blade 2 of the propeller domain of the integrin alphaIIb subunit. Thrombosis and haemostasis, 2004, Volume: 91, Issue:1 Topics: Alanine; Animals; Antibodies, Monoclonal; Cell Adhesion; CHO Cells; Cricetinae; Crystallography, X-Ray; Cytoplasm; DNA, Complementary; Fibrinogen; Humans; Integrins; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligopeptides; Plasmids; Platelet Membrane Glycoprotein IIb; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins	2004
B beta Glu397 and B beta Asp398 but not B beta Asp432 are required for "B:b" interactions. Biochemistry, 2004, Mar-09, Volume: 43, Issue:9 Topics: Alanine; Arginine; Batroxobin; Calcium; Catalysis; Crystallography, X-Ray; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glutamic Acid; Humans; Mutagenesis, Site-Directed; Polymers; Protein Binding; Protein Subunits; Recombinant Proteins; Thrombin	2004
Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3. The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23 Topics: Alanine; Amino Acid Sequence; Blood Platelets; Cell Line; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; DNA, Complementary; Fibrinogen; Flow Cytometry; Humans; Integrin alphaVbeta3; Lysine; Models, Molecular; Models, Statistical; Molecular Sequence Data; Mutation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Software; Structure-Activity Relationship; Thrombasthenia; Transfection	2004
The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha. Molecular endocrinology (Baltimore, Md.), 2004, Volume: 18, Issue:8 Topics: Alanine; Cell Line, Tumor; Enzyme Inhibitors; Fibrinogen; Gene Expression; Humans; Ligands; Mutagenesis, Site-Directed; Phosphorylation; PPAR alpha; Protein Kinase C; Repressor Proteins; RNA, Messenger; Serine; Signal Transduction; Transcriptional Activation	2004
Comparison of thrombin-catalyzed fibrin polymerization and factor XIIIa-catalyzed cross-linking of fibrin among three recombinant variant fibrinogens, gamma 275C, gamma 275H, and gamma 275A. Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:8 Topics: Alanine; Animals; Catalysis; CHO Cells; Cricetinae; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrin; Fibrinogen; Histidine; Humans; Microscopy, Electron, Scanning; Plasmids; Polymers; Recombinant Proteins; Spectrophotometry; Thrombin; Time Factors; Ultraviolet Rays	2004
Hypofibrinogenaemia associated with a novel heterozygous gamma289 Ala -->Val substitution (fibrinogen Dorfen). Thrombosis and haemostasis, 2004, Volume: 92, Issue:6 Topics: Adult; Afibrinogenemia; Alanine; Amino Acid Substitution; Blotting, Western; Child; Chromatography, High Pressure Liquid; DNA; DNA Mutational Analysis; Exons; Family Health; Female; Fibrinogen; Fibrinogens, Abnormal; Heterozygote; Humans; Hydrogen Bonding; Models, Molecular; Mutation; Peptide Mapping; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Trypsin; Valine	2004
Functional analysis of recombinant Bbeta15C and Bbeta15A fibrinogens demonstrates that Bbeta15G residue plays important roles in FPB release and in lateral aggregation of protofibrils. Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5 Topics: Alanine; Animals; Batroxobin; Blotting, Western; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinopeptide B; Glycine; Heterozygote; Humans; Immunoblotting; Kinetics; Microscopy, Electron, Scanning; Mutagenesis; Protein Binding; Recombinant Proteins; Snake Venoms; Thrombin; Time Factors	2005
Staphylococcus aureus adhesion via Spa, ClfA, and SdrCDE to immobilized platelets demonstrates shear-dependent behavior. Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:10 Topics: Adhesins, Bacterial; Alanine; Bacterial Adhesion; Blood Platelets; Blood Proteins; Fibrinogen; Humans; Oligopeptides; Oxazoles; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Staphylococcus aureus; Stress, Mechanical; von Willebrand Factor	2006
Hypofibrinogenaemia associated with common gamma82Ala-->Gly mutation is not mediated by altered mRNA splicing. Thrombosis and haemostasis, 2006, Volume: 96, Issue:4 Topics: Afibrinogenemia; Alanine; Animals; Chlorocebus aethiops; COS Cells; Cytosine; Fibrinogen; Glycine; Guanine; Humans; Mutation; Protein Conformation; RNA Splicing; RNA, Messenger; Sequence Analysis, DNA; Transfection	2006
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists. Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:3 Topics: Administration, Oral; Alanine; Amidines; Binding, Competitive; Blood Platelets; Dimerization; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Humans; In Vitro Techniques; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Isoxazoles; Kinetics; Male; Models, Molecular; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrrolidines; Reference Values; Structure-Activity Relationship; Tirofiban; Tyrosine	2007
Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain. Thrombosis and haemostasis, 2007, Volume: 98, Issue:4 Topics: Adult; Afibrinogenemia; Alanine; Fibrinogen; Glycine; Haplotypes; Hemorrhage; Heterozygote; Humans; Male; Models, Genetic; Mutation; Serine; Spectrometry, Mass, Electrospray Ionization; Time Factors	2007
Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin. Journal of neurology, 2007, Volume: 254, Issue:12 Topics: ABO Blood-Group System; Administration, Oral; Aged; Alanine; Anticoagulants; Arteries; Blood Proteins; Brain Ischemia; Case-Control Studies; Confidence Intervals; Female; Fibrinogen; Genetic Variation; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Odds Ratio; Risk Factors; Threonine	2007
Engineering thrombin for selective specificity toward protein C and PAR1. The Journal of biological chemistry, 2010, Jun-18, Volume: 285, Issue:25 Topics: Alanine; Base Sequence; Fibrinogen; Humans; Kinetics; Ligands; Molecular Conformation; Molecular Sequence Data; Mutagenesis; Mutation; Protein Binding; Protein C; Protein Engineering; Receptor, PAR-1; Thrombin	2010
Effects of the Ala379Val polymorphism of lipoprotein-associated phospholipase A2 on thrombosis and inflammation in hypertensive patients. International journal of cardiology, 2011, Oct-20, Volume: 152, Issue:2 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Alanine; Fibrinogen; Gene Frequency; Genotype; Heterozygote; Humans; Hypertension; Inflammation; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Thrombosis; Valine	2011
Fibrinogen residue γAla341 is necessary for calcium binding and 'A-a' interactions. Thrombosis and haemostasis, 2012, Volume: 107, Issue:5 Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blood Coagulation; Calcium; CHO Cells; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Fibrinopeptide A; Fibrinopeptide B; Humans; Kinetics; Microscopy, Electron, Scanning; Models, Molecular; Molecular Sequence Data; Mutation; Oligopeptides; Protein Conformation; Protein Multimerization; Protein Subunits; Thrombin; Transfection; Valine	2012
Mapping of the fibrinogen-binding site on the staphylocoagulase C-terminal repeat region. The Journal of biological chemistry, 2022, Volume: 298, Issue:1 Topics: Alanine; Bacterial Proteins; Binding Sites; Coagulase; Fibrin; Fibrinogen; Protein Binding; Prothrombin; Terminal Repeat Sequences	2022