alanine has been researched along with epidermal growth factor in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.43) | 18.7374 |
| 1990's | 17 (48.57) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoshi, K; Kasai, H; Kohri, K; Koide, H; Miyake, T; Muto, Y; Sasaki, T; Takahashi, S; Takusari, H; Tsukumo, K | 1 |
| Gill, GN; Rosenfeld, MG; Wells, A; Welsh, JB | 1 |
| Bajaj, SP; Birktoft, JJ; Kasper, CK; Kuppuswamy, MN; Saini, R; Spitzer, SG | 1 |
| Chen, WS; Gill, GN; Herbst, JJ; Lazar, CS; Lund, KA; Rosenfeld, MG; Walsh, BJ; Walton, GM; Welsh, JB; Wiley, HS | 1 |
| Carpenter, CD; Chen, WS; Evans, RM; Gill, GN; Lazar, CS; Lin, CR; Rosenfeld, MG | 1 |
| McGivan, JD; Moule, SK | 1 |
| James, PS; Smith, MW; Tivey, DR; Wilson, TJ | 1 |
| Bucher, NL; McGowan, JA | 1 |
| Leonard, JC; Lundh, E; Morser, J; Nagashima, M; Parkinson, JF | 1 |
| Salloum, RM; Schultz, GS; Souba, WW; Stevens, BR | 1 |
| Hiramatsu, Y; Kudo, T; Masuyama, H | 1 |
| Camp, HS; Tafuri, SR | 1 |
| Ganapathy, V; Kekuda, R; Leibach, FH | 1 |
| Dickinson, CD; Kelly, CR; Ruf, W | 1 |
| Gu, LH; Iannoli, P; Miller, JH; Ryan, CK; Sax, HC; Ziegler, TR | 1 |
| Castellino, FJ; Cheng, CH; Geng, JP | 1 |
| Arakawa, T; Kobayashi, K; Tarnawski, A | 1 |
| Downing, AK; Handford, PA; Whiteman, P | 1 |
| Fleck, C; Pertsch, J | 2 |
| Motoi, H; Suzuki, Y | 1 |
| Ishiwari, K; Kawakatsu, H; Matsumura, T; Nishida, M; Sawada, T; Tamai, M | 1 |
| Harriott, P; McFerran, NV; Nelson, J; Scott, WN; Walker, B | 1 |
| Endo, T; Hanakawa, Y; Hashimoto, K; Higashiyama, S; Matsuzawa, Y; Miyagawa, JI; Nakagawa, T; Ohmoto, H; Shirakata, Y; Taniguchi, N; Tokumaru, S; Yamamori, K; Yoshino, K | 1 |
| Even, L; Ravid, S; Straussman, R | 1 |
| Besner, GE; Brigstock, DR; Davis-Fleische, KM | 1 |
| Chang, YJ; Hamaguchi, N; Hsu, YC; Lin, SW; Wu, HL | 1 |
| Bonkobara, M; Inaba, M; Matsuki, N; Ohmori, T; Ono, K; Thongsong, B | 1 |
| Grammatopoulos, TN; Miranda, M; Sorkin, A; Sorkina, T; Zawada, WM | 1 |
| Jiang, H; Liu, X; Luo, C; Luo, X; Shen, J; Xu, L; Zheng, S; Zhou, M | 1 |
| Manithody, C; Rezaie, AR; Yang, L | 2 |
| Adachi, S; Iwamoto, R; Mekada, E; Mizushima, H; Ohishi, M; Wang, X | 1 |
| Argetsinger, LS; Carter-Su, C; Cline, JM; Jensen, ON; Kouadio, JL; Mazurkiewicz-Munoz, AM; Stensballe, A | 1 |
| Itoh, K; Itoh, S; Shinohara, H | 1 |
35 other study(ies) available for alanine and epidermal growth factor
| Article | Year |
|---|---|
Recognition of an antiparallel beta-sheet structure of human epidermal growth factor by its receptor. Site-directed mutagenesis studies of Ala-30 and Asn-32.
Topics: Alanine; Asparagine; Binding, Competitive; Epidermal Growth Factor; ErbB Receptors; Humans; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Protein Conformation | 1992 |
A negative feedback loop attenuates EGF-induced morphological changes.
Topics: Alanine; Animals; Cell Line; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Feedback; Humans; Microscopy, Electron, Scanning; Mutation; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Factor IXHollywood: substitution of Pro55 by Ala in the first epidermal growth factor-like domain.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Epidermal Growth Factor; Exons; Factor IX; Factor IXa; Genetic Markers; Hemophilia A; Humans; Molecular Sequence Data; Mutation; Partial Thromboplastin Time; Polymerase Chain Reaction; Proline; Promoter Regions, Genetic; Protein Conformation | 1990 |
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
Topics: Alanine; Animals; Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Ligands; Mice; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1990 |
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms.
Topics: Alanine; Cell Line; DNA; Epidermal Growth Factor; ErbB Receptors; Humans; Methionine; Mutation; Phosphorylation; Protein Conformation; Protein Kinase C; Receptors, Cell Surface; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic | 1986 |
Epidermal growth factor, like glucagon, exerts a short-term stimulation of alanine transport in rat hepatocytes.
Topics: Alanine; Animals; Biological Transport; Epidermal Growth Factor; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1987 |
Dexamethasone selectively increases sodium-dependent alanine transport across neonatal piglet intestine.
Topics: Alanine; Animals; Animals, Newborn; Biological Transport; Cell Division; Dexamethasone; Epidermal Growth Factor; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Sodium; Swine | 1987 |
Pyruvate promotion of DNA synthesis in serum-free primary cultures of adult rat hepatocytes.
Topics: Alanine; Animals; Autoradiography; Cells, Cultured; DNA; Drug Synergism; Epidermal Growth Factor; Insulin; Liver; Pyruvates; Rats | 1983 |
Alanine-scanning mutagenesis of the epidermal growth factor-like domains of human thrombomodulin identifies critical residues for its cofactor activity.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; Enzyme Activation; Epidermal Growth Factor; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Binding; Protein C; Protein Structure, Secondary; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; Structure-Activity Relationship; Thrombin | 1993 |
Regulation of small intestinal glutamine transport by epidermal growth factor.
Topics: Alanine; Animals; Biological Transport; Cell Division; DNA; Epidermal Growth Factor; Glutamine; Intestine, Small; Jejunum; Kinetics; Male; Microvilli; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
Effect of epidermal growth factor on placental amino acid transport and regulation of epidermal growth factor receptor expression of hepatocyte in rat.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Antibodies; Binding, Competitive; Biological Transport; Body Weight; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Insulin; Insulin-Like Growth Factor I; Iodine Radioisotopes; Isoleucine; Litter Size; Liver; Maternal-Fetal Exchange; Organ Culture Techniques; Placenta; Pregnancy; Radioligand Assay; Rats; Rats, Wistar | 1996 |
Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Epidermal Growth Factor; Genes, Reporter; Humans; Mice; Microbodies; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Point Mutation; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Transcription Factors; Transcription, Genetic; Transfection | 1997 |
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR.
Topics: Alanine; Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Aurintricarboxylic Acid; Biological Transport; Carrier Proteins; Choriocarcinoma; Cloning, Molecular; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; HeLa Cells; Humans; Isoflavones; Leucine; Phosphorylation; Placenta; Tumor Cells, Cultured; Tyrosine; Uterine Neoplasms | 1997 |
Ca2+ binding to the first epidermal growth factor module of coagulation factor VIIa is important for cofactor interaction and proteolytic function.
Topics: 1-Carboxyglutamic Acid; Alanine; Animals; Asparagine; Binding Sites; Calcium; CHO Cells; Cricetinae; Epidermal Growth Factor; Factor IX; Factor VIIa; Factor X; Glutamine; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Structure-Activity Relationship | 1997 |
Epidermal growth factor and human growth hormone accelerate adaptation after massive enterectomy in an additive, nutrient-dependent, and site-specific fashion.
Topics: Alanine; Animals; Arginine; Duodenum; Epidermal Growth Factor; Glucose; Glutamine; Human Growth Hormone; Humans; Ileum; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Intestinal Absorption; Intestinal Mucosa; Jejunum; Leucine; Male; Microvilli; Rabbits; Recombinant Proteins; RNA, Messenger; Transcription, Genetic | 1997 |
The functions of the first epidermal growth factor homology region of human protein C as revealed by a charge-to-alanine scanning mutagenesis investigation.
Topics: Alanine; Amino Acid Sequence; Calcium; Cell Line; Epidermal Growth Factor; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein C; Protein Conformation; Recombinant Fusion Proteins; Structure-Activity Relationship | 1997 |
Rebamipide treatment activates epidermal growth factor and its receptor expression in normal and ulcerated gastric mucosa in rats: one mechanism for its ulcer healing action?
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Gene Expression Regulation; Male; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1998 |
NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Cloning, Molecular; DNA Primers; Epidermal Growth Factor; Fibrillin-1; Fibrillins; Humans; Magnetic Resonance Spectroscopy; Microfilament Proteins; Proline; Protein Conformation | 1998 |
Epidermal growth factor (EGF) increases the renal amino acid transport capacity in amino acid loaded rats.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Epidermal Growth Factor; Female; Glutamine; Insulin; Kidney; p-Aminohippuric Acid; Rats; Rats, Wistar; Time Factors | 1998 |
Influence of epidermal growth factor (EGF) on renal transport of PAH and amino acids in amino acid loaded rats.
Topics: Absorption; Alanine; Amino Acids; Animals; Arginine; Biological Transport; Epidermal Growth Factor; Female; Glomerular Filtration Rate; Glutamine; Kidney; p-Aminohippuric Acid; Rats; Rats, Wistar | 1999 |
Glucose and amino acid metabolism in Caco-2 cells maintained in a serum- and hormone-free medium.
Topics: Alanine; Amino Acids; Caco-2 Cells; Culture Media, Serum-Free; Epidermal Growth Factor; Glucose; Glutamine; Hormones; Humans; Proline | 1999 |
Effect of epidermal growth factor on sodium-dependent L-alanine transport in LLC-PK1 cells.
Topics: Alanine; Animals; Biological Transport, Active; Epidermal Growth Factor; Humans; LLC-PK1 Cells; Protein Kinase C; Sodium; Swine; Tetradecanoylphorbol Acetate | 2000 |
Development of laminin receptor agonists: identification of important functional residues by alanine scanning.
Topics: Alanine; Amino Acid Sequence; Animals; Drug Design; Epidermal Growth Factor; Laminin; Mice; Models, Molecular; Molecular Weight; Peptides; Protein Binding; Protein Conformation; Protein Isoforms; Receptors, Laminin; Structure-Activity Relationship | 2000 |
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing.
Topics: Alanine; Animals; Cell Movement; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Female; Heparin-binding EGF-like Growth Factor; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Keratinocytes; Ligands; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Protease Inhibitors; Skin; Wound Healing | 2000 |
Myosin II heavy chain isoforms are phosphorylated in an EGF-dependent manner: involvement of protein kinase C.
Topics: Alanine; Amino Acid Substitution; Blotting, Western; Cell Line; Cell Membrane; Cloning, Molecular; Enzyme Activation; Epidermal Growth Factor; Humans; Male; Mutagenesis, Site-Directed; Myosin Heavy Chains; Myosin Type II; Phosphorylation; Prostate; Protein Isoforms; Protein Kinase C; Protein Transport; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties.
Topics: Alanine; Binding Sites; Blotting, Western; Chromatography, High Pressure Liquid; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Genetic Vectors; Glycosylation; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Recombinant Proteins; Threonine; Vaccinia virus | 2001 |
Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.
Topics: Alanine; Asparagine; Epidermal Growth Factor; Factor IX; Factor VIIIa; Factor X; Glycine; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Proteins | 2002 |
Effects of epidermal growth factor on placental amino acids uptake in pregnant rats.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Epidermal Growth Factor; Female; Leucine; Microvilli; Placenta; Pregnancy; Proline; Random Allocation; Rats; Rats, Wistar; Sodium; Up-Regulation | 2002 |
Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.
Topics: Alanine; Amino Acid Sequence; Animals; Aorta; Aspartic Acid; Bacterial Proteins; Biotinylation; Cell Membrane; Cells, Cultured; Dopamine Plasma Membrane Transport Proteins; Endoplasmic Reticulum; Endothelium, Vascular; Epidermal Growth Factor; Fluorescence Resonance Energy Transfer; Glycine; Luminescent Proteins; Lysine; Membrane Glycoproteins; Membrane Transport Proteins; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Nerve Tissue Proteins; Neurons; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Swine; Transfection | 2004 |
Computational analysis of molecular basis of 1:1 interactions of NRG-1beta wild-type and variants with ErbB3 and ErbB4.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Conserved Sequence; Epidermal Growth Factor; ErbB Receptors; Genetic Variation; Models, Biological; Mutagenesis, Site-Directed; Neuregulin-1; Protein Isoforms; Receptor, ErbB-3; Receptor, ErbB-4; Recombinant Proteins; Solvents | 2005 |
Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition.
Topics: Alanine; Animals; Arginine; Binding Sites; Binding, Competitive; Catalysis; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor Xa; Heparin; Humans; Kinetics; Lipoproteins; Lysine; Models, Biological; Mutagenesis; Mutation; Phospholipids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serpins | 2005 |
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells | 2006 |
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.
Topics: 3T3 Cells; Alanine; Animals; Butadienes; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Growth Hormone; Humans; Janus Kinase 2; MAP Kinase Kinase 1; Mass Spectrometry; Mice; Mutation; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate | 2006 |
Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.
Topics: Alanine; Amino Acid Substitution; Arginine; Asparagine; Epidermal Growth Factor; Factor VIIa; Factor X; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Thromboplastin | 2007 |
Regulation of human corneal epithelial mucins by rebamipide.
Topics: Alanine; Anti-Ulcer Agents; Biomarkers; Blotting, Western; Cell Line; Cell Proliferation; Epidermal Growth Factor; Epithelium, Corneal; ErbB Receptors; Humans; Ki-67 Antigen; Mucin-1; Mucin-4; Mucin-6; Proliferating Cell Nuclear Antigen; Quinolones; Real-Time Polymerase Chain Reaction | 2014 |