alanine has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoyagi, H; Costa, T; Izumiya, N; Kato, T; Lee, S; Mihara, H; Shimohigashi, Y | 1 |
| George, SR; O'Dowd, BF; Pak, Y | 1 |
| Bühling, F; Höllt, V; Klutzny, M; Koch, T; Raulf, E; Schröder, H; Schulz, S; Wolf, R | 1 |
| Deng, HB; Guang, W; Wang, JB | 1 |
| Burd, AL; Chang, CY; El Kouhen, R; Erickson-Herbrandson, LJ; Law, PY; Loh, HH | 1 |
| Chaipatikul, V; Law, PY; Loh, HH | 1 |
6 other study(ies) available for alanine and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Tyr1-substituted and fluorescent Pya1-enkephalins bind strongly and selectively to mu and delta opiate receptors.
Topics: Alanine; Animals; Binding, Competitive; Crystallography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Pyrenes; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 1986 |
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 1997 |
Replacement of threonine 394 by alanine facilitates internalization and resensitization of the rat mu opioid receptor.
Topics: Alanine; Amino Acid Substitution; Analgesics, Opioid; Animals; Cyclic AMP; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression Regulation, Neoplastic; Mutation; Rats; Receptors, Cell Surface; Receptors, Opioid, mu; Threonine; Tumor Cells, Cultured | 1999 |
Selected cysteine residues in transmembrane domains of mu-opioid receptor are critical for effects of sulfhydryl reagents.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; COS Cells; Cricetinae; Cysteine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethyl Methanesulfonate; Humans; Ligands; Membranes; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Narcotic Antagonists; Radioligand Assay; Receptors, Opioid, mu; Sulfhydryl Reagents | 2000 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Diprenorphine; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 2001 |
Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain.
Topics: Adenylyl Cyclases; Alanine; Analgesics, Opioid; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Deletion; Humans; Membrane Proteins; Morphine; Narcotic Antagonists; Pertussis Toxin; Protein Structure, Tertiary; Receptors, Opioid, mu | 2003 |