Compounds > alanine

alanine and dysiherbaine

alanine has been researched along with dysiherbaine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.17)18.2507
2000's18 (75.00)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Minei, R1
Hawryluk, NA; Snider, BB1
Contractor, A; Ghetti, A; Green, T; Kamiya, H; Oiwa, C; Sakai, R; Shimamoto, K; Swanson, GT; Tamura-Horikawa, Y1
Kamiya, H; Koike, T; Oiwa, C; Sakai, R; Sasaki, M; Shimamoto, K; Suzuki, K; Tachibana, K; Yano, A1
Chamberlin, AR; Phillips, D1
Che, W; Contractor, A; Green, T; Heinemann, SF; Kamiya, H; Sakai, R; Swanson, GT1
Hashimoto, J; Iba, R; Miyata, O; Naito, T1
Ito, K; Johnson, MS; Pentikäinen, OT; Sakai, R; Sanders, JM; Sasaki, M; Settimo, L; Shoji, M; Swanson, GT1
Ishibashi, H; Ogasawara, M; Shiro, T; Tamura, O; Toyao, A1
Chamberlin, AR; Cohen, JL; Limon, A; Miledi, R1
Johnson, MS; Pentikäinen, OT; Pentikäinen, U; Sakai, R; Sanders, JM; Sasaki, M; Settimo, L; Shoji, M; Swanson, GT1
Akiyama, N; Lash, LL; Oikawa, M; Sakai, R; Sanders, JM; Sasaki, M; Shimamoto, K; Shoji, M; Swanson, GT; Tsubone, K1
Hatakeyama, S; Ishihara, J; Matsumura, T; Takahashi, K1
Akiyama, N; Aoki, K; Oikawa, M; Sakai, R; Sasaki, M; Shimamoto, K; Shoji, M; Tsubone, K1
Jimbo, M; Kamiya, H; Kimura, A; Kobiyama, A; Koike, K; Sakai, R; Yoshida, K1
Bunch, L; Krogsgaard-Larsen, P1
del Aguila, MA; Fernández de la Pradilla, R; Lwoff, N; Tortosa, M; Viso, A1
Sakai, R; Swanson, GT1
Frydenvang, K; Gajhede, M; Kastrup, JS; Lash, LL; Naur, P; Pentikaïnen, OT; Pickering, DS; Postila, PA; Sakai, R; Sasaki, M; Smith, CM; Swanson, GT1
Pentikäinen, OT; Postila, PA; Swanson, GT1
Lash-Van Wyhe, LL; Pentikäinen, OT; Postila, PA; Sakai, R; Sasaki, M; Swanson, GT; Tsubone, K1
Doh-ura, K; Ikeda-Saito, M; Sakai, R; Sasaki, M; Shinohara, M; Takayama, K; Tanaka, H; Teruya, K; Unno, M1
Celindro, NC; Kang, SH; Kim, TW1
Cho, JH; Do, H; Gilbertson, SR; Kang, CW1

Reviews

2 review(s) available for alanine and dysiherbaine

ArticleYear
Subtype selective kainic acid receptor agonists: discovery and approaches to rational design.
    Medicinal research reviews, 2009, Volume: 29, Issue:1

    Topics: Alanine; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Kainic Acid; Ligands; Quisqualic Acid; Receptors, Kainic Acid; Rhodophyta; Structure-Activity Relationship

2009
Ligands for ionotropic glutamate receptors.
    Progress in molecular and subcellular biology, 2009, Volume: 46

    Topics: Alanine; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; GluK2 Kainate Receptor; Kainic Acid; Ligands; Mammals; Mollusk Venoms; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta

2009

Other Studies

22 other study(ies) available for alanine and dysiherbaine

ArticleYear
[Effects of a new excitotoxic amino acid, dysiherbaine, on cultured Müller cells].
    Nippon Ganka Gakkai zasshi, 1999, Volume: 103, Issue:8

    Topics: Alanine; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Heterocyclic Compounds, 2-Ring; Neurotoxins; Rabbits; Retina

1999
Synthesis of (-)-dysiherbaine.
    Organic letters, 2000, Mar-09, Volume: 2, Issue:5

    Topics: Alanine; Amino Acids; Bridged Bicyclo Compounds, Heterocyclic; Heterocyclic Compounds, 2-Ring; Hydrolysis; Magnetic Resonance Spectroscopy; Stereoisomerism

2000
Pharmacological properties of the potent epileptogenic amino acid dysiherbaine, a novel glutamate receptor agonist isolated from the marine sponge Dysidea herbacea.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Alanine; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Convulsants; Diagnostic Imaging; Excitatory Amino Acid Agonists; In Vitro Techniques; Injections, Intraventricular; Male; Mice; Neurons; Porifera; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Synaptic Membranes

2001
Isolation, structure determination, and synthesis of neodysiherbaine A, a new excitatory amino acid from a marine sponge.
    Organic letters, 2001, May-17, Volume: 3, Issue:10

    Topics: Alanine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Epoxy Compounds; Excitatory Amino Acid Agonists; Heterocyclic Compounds, 3-Ring; Mice; Molecular Structure; Porifera; Radioligand Assay; Rats; Receptors, Kainic Acid; Synaptic Membranes

2001
Total synthesis of dysiherbaine.
    The Journal of organic chemistry, 2002, May-17, Volume: 67, Issue:10

    Topics: Alanine; Alkylation; Biological Factors; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Chemistry, Organic; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction

2002
Differential activation of individual subunits in heteromeric kainate receptors.
    Neuron, 2002, May-16, Volume: 34, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Humans; Macromolecular Substances; Models, Neurological; Mutagenesis, Site-Directed; Mutation; Neurons; Receptors, Kainic Acid; Synapses; Synaptic Transmission

2002
A convenient route to the furopyran core of dysiherbaine.
    Organic & biomolecular chemistry, 2003, Mar-07, Volume: 1, Issue:5

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Molecular Structure; Pyrans

2003
Divergent pharmacological activity of novel marine-derived excitatory amino acids on glutamate receptors.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Excitatory Amino Acids; Humans; Kainic Acid; Models, Molecular; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate

2005
Stereoselective syntheses of 4-hydroxy 4-substituted glutamic acids.
    The Journal of organic chemistry, 2005, Jun-10, Volume: 70, Issue:12

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cyclization; Glutamic Acid; Indicators and Reagents; Indoles; Molecular Structure; Stereoisomerism

2005
Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine.
    Bioorganic & medicinal chemistry letters, 2006, Apr-15, Volume: 16, Issue:8

    Topics: Alanine; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ligands; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2006
Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.
    Molecular pharmacology, 2006, Volume: 69, Issue:6

    Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Electrophysiology; Humans; Ligands; Mutation; Porifera; Protein Structure, Tertiary; Protein Subunits; Radioligand Assay; Receptors, Kainic Acid

2006
Total synthesis and biological evaluation of neodysiherbaine A and analogues.
    The Journal of organic chemistry, 2006, Jul-07, Volume: 71, Issue:14

    Topics: Alanine; Animals; Binding, Competitive; Biological Assay; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Dose-Response Relationship, Drug; Humans; Injections, Intraventricular; Mice; Molecular Structure; Receptors, Kainic Acid; Seizures; Stereoisomerism; Structure-Activity Relationship

2006
A highly stereocontrolled total synthesis of dysiherbaine.
    Chemical communications (Cambridge, England), 2007, Oct-28, Issue:40

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Molecular Structure; Stereoisomerism

2007
Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships.
    The Journal of organic chemistry, 2008, Jan-04, Volume: 73, Issue:1

    Topics: Alanine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Drug Evaluation, Preclinical; Injections, Intraventricular; Mice; Models, Molecular; Molecular Structure; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Stereoisomerism; Structure-Activity Relationship

2008
Cellular origin of dysiherbaine, an excitatory amino acid derived from a marine sponge.
    Chembiochem : a European journal of chemical biology, 2008, Mar-03, Volume: 9, Issue:4

    Topics: Alanine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyanobacteria; DNA, Ribosomal; Excitatory Amino Acids; Immunohistochemistry; Mass Spectrometry; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Molecular Structure; Oceans and Seas; Phylogeny; Porifera; Symbiosis

2008
[2,3]-Sigmatropic rearrangements of 3-sulfinyl dihydropyrans: application to the syntheses of the cores of ent-dysiherbaine and deoxymalayamicin A.
    The Journal of organic chemistry, 2008, Nov-21, Volume: 73, Issue:22

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Hydroxylation; Pyrans; Stereoisomerism; Sulfoxides; Uracil

2008
Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.
    The Journal of biological chemistry, 2009, May-22, Volume: 284, Issue:21

    Topics: Alanine; Amino Acids; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Computer Simulation; Crystallography, X-Ray; Glutamic Acid; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Receptors, Kainic Acid

2009
Exploring kainate receptor pharmacology using molecular dynamics simulations.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Ligands; Marine Toxins; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Conformation; Receptors, Kainic Acid; Structure-Activity Relationship

2010
Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.
    Neuropharmacology, 2010, Volume: 58, Issue:3

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Green Fluorescent Proteins; Humans; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Receptors, Kainic Acid; Structure-Activity Relationship; Time Factors; Transfection; Tritium

2010
Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.
    Journal of molecular biology, 2011, Oct-28, Volume: 413, Issue:3

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Crystallography, X-Ray; GluK2 Kainate Receptor; Glutamic Acid; Humans; Marine Toxins; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Receptors, Kainic Acid

2011
Total synthesis of (-)-dysiherbaine.
    Chemical communications (Cambridge, England), 2012, Jun-25, Volume: 48, Issue:50

    Topics: Alanine; Bridged Bicyclo Compounds, Heterocyclic; Molecular Conformation; Stereoisomerism

2012
Enantioselective Synthesis of (-)-Dysiherbaine.
    Organic letters, 2015, Aug-21, Volume: 17, Issue:16

    Topics: Alanine; Alkenes; Amino Acids; Animals; Biological Products; Bridged Bicyclo Compounds, Heterocyclic; Marine Biology; Molecular Structure; Porifera; Receptors, Glutamate; Receptors, Kainic Acid; Stereoisomerism

2015