Compounds > alanine

alanine and diclofenac

alanine has been researched along with diclofenac in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (14.29)	29.6817
2010's	10 (71.43)	24.3611
2020's	2 (14.29)	2.80

Authors

Authors	Studies
Fukui, H; Takakura, Y; Yajima, H; Yamao, J	1
Ando, T; Goto, H; Hirooka, Y; Itoh, A; Maeda, O; Nakamura, M; Niwa, Y; Ohmiya, N	1
Kumar, CK; Rasheed, A	1
Ehara, A; Fujimori, S; Gudis, K; Kobayashi, T; Mitsui, K; Sakamoto, C; Seo, T; Takahashi, Y; Tanaka, S; Tatsuguchi, A; Yonezawa, M	1
Chen, ML; Diao, L; Hu, J; Jin, J; Liu, XC; Mei, Q; Xu, JM; Yao, Q	1
Amagase, K; Satoh, H; Takeuchi, K	1
Cooper, DL; Harirforoosh, S; Wood, RC; Wyatt, JE	1
Bullins, KW; Denham, JW; Hanley, AV; Hanley, GA; Harirforoosh, S; Panus, PC; Wood, RC; Wyatt, JE	1
Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH	1
Denham, JW; Harirforoosh, S; Murrell, DE; Panus, PC; Rahmasari, Y	1
Haraguchi, T; Kojima, H; Li, D; Nakamura, S; Shiraishi, S; Uchida, T; Yoshida, M	1
Bellver, MVM; Bonillo Martínez, AD; Galán, ICR	1
Cao, X; Jing, L; Mou, S; Xu, N; Yu, Z; Zhang, C	1
Hazama, K; Imai, T; Kosuge, Y; Ootsuka, S; Suzuki, S	1

Trials

3 trial(s) available for alanine and diclofenac

Article	Year
Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study. Journal of gastroenterology, 2008, Volume: 43, Issue:4 Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Follow-Up Studies; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Prospective Studies; Quinolones; Severity of Illness Index; Treatment Outcome	2008
Rebamipide has the potential to reduce the intensity of NSAID-induced small intestinal injury: a double-blind, randomized, controlled trial evaluated by capsule endoscopy. Journal of gastroenterology, 2011, Volume: 46, Issue:1 Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Diclofenac; Double-Blind Method; Humans; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Quinolones; Treatment Outcome; Young Adult	2011
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity. Gut and liver, 2014, Volume: 8, Issue:4 Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanones; Diclofenac; Double-Blind Method; Drug Administration Schedule; Gastric Mucosa; Humans; Meloxicam; Middle Aged; Misoprostol; Nabumetone; Quinolones; Stomach Ulcer; Thiazines; Thiazoles; Treatment Outcome	2014

Other Studies

11 other study(ies) available for alanine and diclofenac

Article	Year
Up-to-date information on gastric mucosal lesions from long-term NSAID therapy in orthopedic outpatients: a study using logistic regression analysis. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2007, Volume: 12, Issue:4 Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Bone Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Endoscopy; Famotidine; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Life Style; Male; Middle Aged; Outpatients; Peptic Ulcer; Prospective Studies; Quinolones; Risk Factors	2007
Design, synthesis, hydrolysis kinetics and phamacodynamic profiles of histidine and alanine conjugates of aceclofenac. Acta pharmaceutica (Zagreb, Croatia), 2010, Volume: 60, Issue:1 Topics: Alanine; Animals; Diclofenac; Drug Design; Histidine; Humans; Hydrolysis; Pain Measurement; Rats; Rats, Wistar	2010
Rebamipide suppresses diclofenac-induced intestinal permeability via mitochondrial protection in mice. World journal of gastroenterology, 2012, Mar-14, Volume: 18, Issue:10 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Mice; Mitochondria; Mitochondrial Swelling; NAD; Permeability; Quinolones; Random Allocation	2012
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Response Relationship, Drug; Gastric Mucins; Gastrointestinal Agents; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Misoprostol; Mucus; Omeprazole; Protective Agents; Proton Pump Inhibitors; Quinolones; Ranitidine; Rats; Rats, Wistar; Sus scrofa; Triazines	2014
Pharmacokinetic interactions between rebamipide and selected nonsteroidal anti-inflammatory drugs in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Mar-12, Volume: 53 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Celecoxib; Diclofenac; Drug Interactions; Male; Protein Binding; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Sulfonamides	2014
Effects of rebamipide on nephrotoxicity associated with selected NSAIDs in rats. European journal of pharmacology, 2013, Nov-15, Volume: 720, Issue:1-3 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cell Adhesion Molecules; Creatinine; Diclofenac; Dinoprostone; Drug Interactions; Kidney; Kidney Diseases; Male; Nitric Oxide; Potassium; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Sodium; Sulfonamides	2013
Celecoxib or diclofenac hepatic status in the presence or absence of rebamipide. European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:17 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Male; Quinolones; Rats; Rats, Sprague-Dawley	2015
Taste-Masking Effect of Chlorogenic Acid (CGA) on Bitter Drugs Evaluated by Taste Sensor and Surface Plasmon Resonance on the Basis of CGA-Drug Interactions. Chemical & pharmaceutical bulletin, 2017, Volume: 65, Issue:2 Topics: Alanine; Amlodipine; Chlorogenic Acid; Diclofenac; Diphenhydramine; Donepezil; Drug Interactions; Etodolac; Indans; Piperidines; Quinolones; Surface Plasmon Resonance; Taste	2017
Application of a Biodegradable Polyesteramide Derived from L-Alanine as Novel Excipient for Controlled Release Matrix Tablets. AAPS PharmSciTech, 2017, Volume: 18, Issue:8 Topics: Alanine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Excipients; Ketoprofen; Polyesters; Polymers; Solubility; Tablets; Tromethamine	2017
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury. International immunopharmacology, 2021, Volume: 90 Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease Models, Animal; Gene Expression Regulation; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; NF-kappa B; Quinolones; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Ulcer; Zonula Occludens-1 Protein	2021
Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER. Scientific reports, 2022, 02-16, Volume: 12, Issue:1 Topics: Adverse Drug Reaction Reporting Systems; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Diclofenac; Drug Therapy, Combination; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Japan; Phenylpropionates; Quinolones; United States; United States Food and Drug Administration	2022