alanine has been researched along with dehydroalanine in 181 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (6.08) | 18.7374 |
| 1990's | 34 (18.78) | 18.2507 |
| 2000's | 42 (23.20) | 29.6817 |
| 2010's | 71 (39.23) | 24.3611 |
| 2020's | 23 (12.71) | 2.80 |
| Authors | Studies |
|---|---|
| Karube, Y; Matsushima, Y | 1 |
| Brzović, PS; Dunn, MF; Ngo, K | 1 |
| Lejeune, PJ; Marriq, C; Venot, N; Vinet, L | 1 |
| Bartone, NA; Bentley, JD; Maclaren, JA | 1 |
| Hallinan, EA | 1 |
| Levy, HL; McInnes, RR; Taylor, RG | 1 |
| Chauhan, VS; Gupta, A | 1 |
| Hayashi, H; Kondo, T; Kondo, Y; Ohmiya, Y | 1 |
| Ando, S; Izumiya, N; Kato, T | 1 |
| Chauhan, VS; Sharma, AK | 1 |
| Kondo, T; Kondo, Y; Ui, N | 1 |
| Palumbo, G | 1 |
| Consevage, MW; Phillips, AT | 1 |
| Ando, S; Aoyagi, H; Izumiya, N; Kato, T; Waki, M | 1 |
| Helmerhorst, E; Jones, AJ; Stokes, GB | 1 |
| Friedman, M; Masri, MS | 1 |
| Cahnmann, HJ; Gavaret, JM; Nunez, J | 1 |
| Campbell, DG; Cohen, P; Cohen, PT; Dalby, KN; MacKintosh, C; MacKintosh, RW | 1 |
| Dodd, HM; Gasson, MJ; Horn, N | 1 |
| Rétey, J; Schuster, B | 2 |
| Bhatnagar, S; Rao, GS; Singh, TP | 1 |
| Alemán, C; Casanovas, J | 1 |
| Langer, M; Lieber, A; Rétey, J | 1 |
| Fransson, B; Grehn, L; Tomkinson, B; Zetterqvist, O | 1 |
| Barra, D; Bossa, F; Scaloni, A | 1 |
| Langer, M; Reck, G; Reed, J; Rétey, J | 1 |
| Alemán, C; Perez, JJ | 1 |
| Buc-Calderon, P; Mason, RP; Roberfroid, M; Sipe, HJ | 1 |
| Alemän, C | 1 |
| Chiu, ML; Folcher, M; Griffin, P; Holt, T; Klatt, T; Thompson, CJ | 1 |
| Cook, PF; Dunn, MF; Tai, CH; Woehl, EU | 1 |
| Cook, PF; Dunn, MF; Hwang, CC; Schnackerz, KD; Tai, CH; Woehl, EU | 1 |
| Boussard, G; Ciszak, E; Kubica, Z; Lisowski, M; Pietrzyński, G; Rzeszotarska, B | 1 |
| Anderson, KS; Gerhardt, E; Lee, M; Liang, PH; Schlichting, I; Schneider, TR | 1 |
| Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY | 1 |
| Bettati, S; Burkhard, P; Cook, PF; Mozzarelli, A; Pucci, AM | 1 |
| Mozzarelli, A; Schnackerz, KD | 1 |
| D'Agostino, B; D'Andrea, LD; Falciani, M; Filippelli, A; Lombardi, A; Nastri, F; Pavone, V; Rossi, F | 1 |
| Demand, J; Knappe, J; Pils, T; Schilling, G; Wagner, AF | 1 |
| Rétey, J; Schulz, GE; Schwede, TF | 1 |
| Chiu, ML; Folcher, M; Katoh, T; Puglia, AM; Seto, H; Thompson, CJ; Vohradsky, J; Yun, BS | 1 |
| Suzen, S; Williams, M | 1 |
| Jemielity, J; Kańska, M; Lewandowicz, A; Paneth, P; Zoń, J | 1 |
| Dalè, G; Dunn, MF; Mozzarelli, A; Peracchi, A; Rossi, GL; Rovegno, B | 1 |
| Hirabayashi, T; Hirako, T; Inai, Y; Oshikawa, T; Yamashita, M | 1 |
| Okeley, NM; van Der Donk, WA; Zhu, Y | 1 |
| Kafarski, P; Latajka, R; Makowski, M; Nowak, K; Pawelczak, M | 1 |
| van der Donk, WA; Zhu, Y | 1 |
| Malkoski, M; Reynolds, EC; Suckau, D; Talbo, GH | 1 |
| Alemán, C; Casanovas, J; Zanuy, D | 1 |
| Murkin, AS; Tanner, ME | 1 |
| Cook, PF; Daum, S; Tai, CH | 1 |
| Dodd, HM; Gasson, MJ; McMullen, LM; Mellon, FA; Rose, NL; Sporns, P | 1 |
| Burk, RF; Caprioli, RM; Hill, KE; Ma, S | 1 |
| Christenson, SD; Liu, W; Shen, B; Toney, MD | 1 |
| KOSHLAND, DE; STRUMEYER, DH; WHITE, WN | 1 |
| Galonić, DP; Gin, DY; Van Der Donk, WA | 1 |
| Hill, JM; Hu, F; LeGrand, RD; Linetsky, M | 1 |
| Ayida, BK; Hermann, T; Simonsen, KB; Vourloumis, D | 1 |
| LeGrand, RD; Linetsky, M | 1 |
| Dunn, MF; Harris, RM; Ngo, H | 1 |
| Seebeck, FP; Szostak, JW | 1 |
| Coban, T; Gurkok, G; Suzen, S | 1 |
| Katakai, R; Katsu, T; Komagoe, K; Oku, H; Shinoda, SS; Yamada, K | 1 |
| Levengood, MR; van der Donk, WA | 1 |
| Oehlmann, W; Schneider, G; Schnell, R; Singh, M | 1 |
| Schiller, SM; Schultz, PG; Wang, J | 1 |
| Farthing, AK; Liu, K; Meinke, PT; Shi, YJ; Xu, L | 1 |
| Alemán, C; Nussinov, R; Rodríguez-Ropero, F; Zanuy, D | 1 |
| Bryndal, I; Kafarski, P; Latajka, R; Lis, T; Lisowski, M; Makowski, M; Picur, B; Rospenk, M | 1 |
| Cernak, TA; Gleason, JL | 1 |
| Beauchamp, JL; Kim, HI | 1 |
| Bar-Or, D; Bar-Or, R; Rael, LT | 1 |
| Bernardes, GJ; Chalker, JM; Davis, BG; Errey, JC | 1 |
| Fewer, DP; Jakobsen, KS; Jokela, J; Kristensen, T; Rohrlack, T; Rouhiainen, L; Sivonen, K; Tooming-Klunderud, A; Wahlsten, M | 1 |
| Chatterjee, C; Cooper, LE; Patton, GC; Paul, M; van der Donk, WA | 1 |
| Archer, MC; Bruce, WR; Corpet, DE; Taché, S | 1 |
| Fukao, M; Kohda, D; Nakayama, J; Obita, T; Sonomoto, K; Yoneyama, F; Zendo, T | 1 |
| Callery, PS; Cooper, AJ; Elliott, M; Konat, GW; Kraszpulski, M; Peer, CJ; Petros, WP; Pinto, JT; Younis, IR | 1 |
| Agren, D; Schneider, G; Schnell, R | 1 |
| Cusack, B; Davey, ZS; Fauq, AH; Healy, B; Maharvi, GM; Moore, BD; Rangachari, V; Rosenberry, TL; Sonoda, LK | 1 |
| Balaram, P; Thakur, SS | 1 |
| Basler, DA; Cagney, JW; Carroll, JA; Chen, ZY; Egodage, K; Lipartito, C; Poruthoor, S; Schlittler, MR; Storrs, SB; Tou, JS; Violand, BN | 1 |
| Cooper, LE; Li, B; van der Donk, WA | 1 |
| Coban, T; Ferreira, PM; Monteiro, LS; Suzen, S | 1 |
| Wang, H; Xian, M; Zhang, J | 1 |
| De Pauw, E; Deleuze, C; Quinton, L | 1 |
| Cho, CS; Choi, EJ; Lee, GT; Lee, S; Rhee, SG; Woo, HA | 1 |
| Chandrasekaran, S; Mishra, R; Ramapanicker, R | 1 |
| Ferreira, PM; Monteiro, LS; Pereira, G | 1 |
| Brodmann, T; Bülow, L; Carlomagno, T; Eggert, U; Frank, R; Girbig, AK; Kalesse, M; Malek, NP; Nickeleit, I; Rentsch, A; Sasse, F; Steinmetz, H | 1 |
| Cho, CS; Rhee, SG | 1 |
| Choi, S; Jeong, J; Jung, Y; Kim, MS; Lee, E; Lee, HY; Lee, KJ; Na, S; Paek, E; Shin, DH | 1 |
| Lei, XG; Wang, SK; Weaver, JD; Zhang, S | 1 |
| Ricardo, A; Seebeck, FP; Szostak, JW | 1 |
| Callery, PS; Cooper, AJ; Pinto, JT | 1 |
| Bernardes, GJ; Chalker, JM; Davis, BG | 1 |
| Brijs, K; Delcour, JA; Lagrain, B; Rombouts, I | 1 |
| Kerwin, BA; Mozziconacci, O; Schöneich, C | 1 |
| Hu, Z; Kim, JS; Kim, YM; Metz, TO; Morgan, WF; Smith, RD; Wiedner, SD; Zhang, Q | 1 |
| Babievsky, KK; Belokon, YN; Gugkaeva, ZT; Hakobyan, KV; Khrustalev, VN; Maleev, VI; Moskalenko, MA; Saghyan, AS; Tsaloev, AT | 1 |
| Chalker, JM; Davis, BG; Lercher, L; Rose, NR; Schofield, CJ | 1 |
| Monteiro, LS; Suárez, AS | 1 |
| Callery, PS; Gannett, PM; Kenyon, AJ; Leonard, SS; Minarchick, VC; Peer, CJ; Rojanasakul, Y; Younis, IR | 1 |
| Deng, WP; Li, H; Liu, YZ; Luo, S; Luo, X; Wang, Z; Yang, WL; Zhang, S | 1 |
| Bougioukou, DJ; Mukherjee, S; van der Donk, WA | 1 |
| Alte, F; Gersch, M; Groll, M; Kolb, R; Sieber, SA | 1 |
| Lyons, B; Schey, KL; Truscott, RJ; Wang, Z | 1 |
| Bondalapati, S; Brik, A; Haj-Yahya, N; Hemantha, HP; Meledin, R; Seenaiah, M | 1 |
| Avenoza, A; Aydillo, C; Busto, JH; Compañón, I; Corzana, F; Peregrina, JM; Zurbano, MM | 1 |
| Broda, MA; Bujak, M; Lis, T; Siodłak, D; Staś, M | 1 |
| Cooper, AJ; Lushchak, VI; Townsend, DM | 1 |
| Bayliss, R; Blagg, J; Richards, M; Rowan, F; Widya, M | 1 |
| Cavina, L; De Marco, R; Gentilucci, L; Greco, A | 1 |
| Breukink, E; Liskamp, RM; Rijkers, DT; Slootweg, JC; van Doremalen, MF; van Herwerden, EF | 1 |
| García-González, MC; Gordillo-Cruz, RE; Hernández-Vázquez, E; Miranda, LD | 1 |
| Chandrasekar, J; Silverman, SK; Wylder, AC | 1 |
| Foley, PJ; Morrison, PM; Warriner, SL; Webb, ME | 1 |
| van der Donk, WA; Yang, X | 1 |
| Castanheira, EM; Ferreira, PM; Hamley, IW; Hilliou, L; Hortelão, AC; Martins, JA; Queiroz, MJ; Vilaça, H | 1 |
| Adamson, C; Ludewig, H; Mann, G; Migaud, M; Naismith, JH; Oueis, E; Redpath, P; Westwood, NJ | 1 |
| Bian, W; Guo, Y; Huang, J; Li, H; Liang, Q; Luo, L; Yang, R; Zhang, Y | 1 |
| Asamizu, S; Hayashi, S; Igarashi, Y; Kurokawa, Y; Oku, N; Onaka, H; Ozaki, T | 1 |
| Carpentier, SC; Delcour, JA; Lambrecht, MA; Rombouts, I | 1 |
| Aronoff, MR; Gold, B; Raines, RT | 1 |
| Chung, JY; Journet, M; Klapars, A; Shevlin, M | 1 |
| Brik, A; Mali, SM; Meledin, R; Singh, SK | 1 |
| McLuckey, SA; Pilo, AL; Zhao, F | 1 |
| McLuckey, SA; Peng, Z; Pilo, AL | 1 |
| Atkins, WM; Bouldin, SD; Guttman, M; Outten, CE; Scian, M | 1 |
| Ahn, J; Ha, S; Kim, J; Kim, R; Kim, S; Lee, HY; Lee, Y; Park, HS; Söll, D; Yang, A | 1 |
| Baldwin, AJ; Bernardes, GJ; Bower, BJ; Chalker, JM; Claridge, TD; Coleman, OD; Davis, BG; Faulkner, S; Galan, SR; Gerstberger, S; Kessler, BM; Khan, M; Lercher, L; Mohammed, S; Ng, WL; Palm-Espling, ME; Phanumartwiwath, A; Raj, R; Schombs, MW; Thézénas, ML; Vallée, MR; Wiewiora, R; Wright, TH | 1 |
| Bosma, T; de Vries, L; de Vries, MP; Kuipers, A; Moll, GN; Rink, R | 1 |
| Arbibe, L; Baleux, F; Chhuon, C; Guerrera, IC; Jang, SM; Lipecka, J; Meijer, BM; Muchardt, C; Reisacher, C; Sansonetti, PJ | 1 |
| Haremza, K; Kafarski, P; Latajka, R; Lenartowicz, P; Makowski, M; Oszywa, B; Pawełczak, M | 1 |
| Bogart, JW; Bowers, AA; Brustad, EM; Ghodge, SV; Gober, JG; Watkins, RR; Wever, WJ | 1 |
| Friedrich, MG; Oakley, AJ; Schey, KL; Truscott, RJW; Wang, Z | 1 |
| Banerjee, S; Ekka, MK; Kaushik, A; Kumaran, S; Mittal, M; Pandya, V; Singh, AK; Singh, RP; Singh, V | 1 |
| Akkapeddi, P; Bernardes, GJL; Boutureira, O; Brindle, KM; Corzana, F; Freedy, AM; Guerreiro, A; Jiménez-Osés, G; Matos, MJ; Neves, AA; Nicholls, K; Rodrigues, T; Somovilla, VJ; Xie, B | 1 |
| Friedrich, MG; Schey, KL; Truscott, RJW; Wang, Z | 1 |
| Brik, A; Kleifeld, O; Mali, SM; Meledin, R | 1 |
| Davis, BG; Wright, TH | 1 |
| Schey, KL; Wang, Z | 1 |
| Dadová, J; Davis, BG; Galan, SR | 1 |
| de Bruijn, AD; Roelfes, G | 2 |
| Bottecchia, C; Noël, T | 1 |
| Buchwald, SL; Khan, RKM; Scully, TD; Zhao, Y | 1 |
| An, L; Cogan, DP; Jiménez-Osés, G; Nair, SK; Navo, CD; van der Donk, WA | 1 |
| Biehl, P; Kruse, JH; Schacher, FH | 1 |
| Kato, K; Kurimoto, E; Nakayoshi, T; Oda, A | 1 |
| Devel, L; Georgiadis, D; Voreakos, K | 1 |
| DeGrado, WF; Ittuveetil, A; Polizzi, NF; Saikam, V; Schnier, PD; Wang, L; Wang, N; Wang, PG; Wang, Q; Yang, B; Zheng, F; Zhu, H | 1 |
| Fan, J; Fu, Y; Li, YM; Shi, J; Wang, Y; Xu, L; Zhang, Z | 1 |
| de Vries, RH; Kuipers, OP; Oudshoorn, R; Roelfes, G; Viel, JH | 1 |
| Bothwell, IR; Cogan, DP; Kim, T; Nair, SK; Reinhardt, CJ; van der Donk, WA | 1 |
| deRamon, E; Ellman, JA; Miller, SJ; Paulson, EK; Scamp, RJ | 1 |
| Aryal, UK; Foreman, DJ; Hicks, LM; Lawler, JT; McLuckey, SA; Parsley, NC | 1 |
| Kelly, MJ; Perkins, JJ; Shah, AA | 1 |
| Abularrage, NS; Chambers, KA; Hill, CJ; Khan, IH; Scheck, RA | 1 |
| de Vries, RH; Roelfes, G | 1 |
| de Bruijn, AD; Roelfes, G; van Lier, RCW | 1 |
| Andersen, JH; Deng, H; Ebel, R; Fang, Q; Gao, Y; Law, S; Lu, Z; Philips, C; Trembleau, L; Wang, S | 1 |
| Fernández-García, C; Foden, CS; Islam, S; Maugeri, L; Powner, MW; Sheppard, TD | 1 |
| de Vries, RH; Kuipers, OP; Roelfes, G; Viel, JH | 1 |
| Avenoza, A; Busto, JH; Corzana, F; Jiménez-Osés, G; Navo, CD; Oroz, P; Peregrina, JM | 1 |
| Chen, H; Fan, Y; Mu, N; Ruan, Z; Wang, S; Wang, W; Zhu, K | 1 |
| Chen, J; Chooi, KP; Davis, BG; Galan, SRG; Garg, N; He, C; Hutchings, GJ; Jones, LH; Lai, KY; Liu, S; Mohammed, S; Nair, SK; Raj, R; Riedl, J; van der Donk, WA; Zeng, M; Zeng, Y; Zhou, TH | 1 |
| Leeuwon, SZ; Liu, WR; Qiao, Y; Yu, G | 1 |
| Correia, JTM; Delgado, JAC; Paixão, MW; Pissinati, EF | 1 |
| Bogie, PM; Bosken, YK; Caulkins, BG; Chang, CA; Drago, VN; Dunn, MF; Ghosh, RK; Gill, AD; Guidoulianov, J; Hassan, A; Hilario, E; Holmes, JB; Hooley, RJ; Liu, V; Long, JR; Mentink-Vigier, F; Mueller, LJ; Mueser, TC; Paulino, J; Perrone, B; Riviere, G; Romero, JA; Struppe, J; Wang, X; Young, RP | 1 |
| Bai, S; Feng, X; Huang, SY; Lin, L; Modica, J; Mrksich, M; Song, J; Szymczak, LC; Tao, H; Wang, Y; Yang, A | 1 |
| Bell, AG; Benavides, I; Deming, TJ; Evans, D; Houk, KN; Raftery, ED; Scott, WA | 1 |
| Jongkees, SAK; Liu, M; Sovrovic, M; Suga, H | 1 |
| Guo, T; Liu, J; Tang, S; Wang, C; Wang, H; Wang, X | 1 |
| Beelen, M; Dziuk, B; Kafarski, P; Lenartowicz, P; Makowski, M; Wanat, W | 1 |
| Bartoccini, F; Bartolucci, S; Piersanti, G; Retini, M | 1 |
| Gugkaeva, ZT; Larionov, VA; Maleev, VI; Mardiyan, ZZ; Poghosyan, AS; Saghyan, AS; Smol'yakov, AF | 1 |
| Bortolini, O; De Risi, C; Di Carmine, G; Droghetti, F; Massi, A; Natali, M; Poletti, L; Ragno, D | 1 |
| Bao, G; E, R; Guo, X; He, Z; Li, Y; Song, X; Sun, W; Wang, P; Xie, J; Yu, T | 1 |
4 review(s) available for alanine and dehydroalanine
| Article | Year |
|---|---|
Histidase and histidinemia. Clinical and molecular considerations.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Animals; Histidine; Histidine Ammonia-Lyase; Humans; Infant, Newborn; Molecular Sequence Data; Neonatal Screening; Phenylalanine Ammonia-Lyase; Skin; Urocanic Acid | 1991 |
Reversible and irreversible protein glutathionylation: biological and clinical aspects.
Topics: Alanine; Aldehydes; Alzheimer Disease; Apoptosis; Busulfan; Cataract; Cell Cycle; Cystic Fibrosis; Diabetes Mellitus, Type 2; Glutathione; Glutathione Disulfide; Glutathione Transferase; Neoplasms; Oxidation-Reduction; Oxidative Stress; Protein Folding; Proteins; Signal Transduction; Sulfides | 2011 |
Synthesis of modified proteins via functionalization of dehydroalanine.
Topics: Alanine; Animals; Biocatalysis; Chemistry Techniques, Synthetic; Humans; Models, Molecular; Protein Processing, Post-Translational; Proteins | 2018 |
Photocatalytic Modification of Amino Acids, Peptides, and Proteins.
Topics: Alanine; Amino Acids; Catalysis; Cysteine; Light; Methionine; Oxidation-Reduction; Peptides; Proteins; Tryptophan | 2019 |
177 other study(ies) available for alanine and dehydroalanine
| Article | Year |
|---|---|
Letter: alpha-aminoacrylate schiff base in nonenzymatic pyridoxal catalysis.
Topics: Acrylates; Alanine; Catalysis; Pyridoxal; Schiff Bases; Spectrum Analysis | 1976 |
Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex.
Topics: Alanine; Allosteric Regulation; Catalysis; Glycerophosphates; Indoles; Kinetics; Multienzyme Complexes; Protein Conformation; Salmonella typhimurium; Serine; Spectrum Analysis; Tryptophan Synthase | 1992 |
Hormone formation in the isolated fragment 1-171 of human thyroglobulin involves the couple tyrosine 5 and tyrosine 130.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Goiter; Humans; In Vitro Techniques; Molecular Sequence Data; Monoiodotyrosine; Peptides; Pyroglutamyl-Peptidase I; Structure-Activity Relationship; Thyroglobulin; Thyroxine; Trypsin; Tyrosine | 1991 |
Determination of dehydroalanine residues in proteins and peptides: an improved method.
Topics: Alanine; Hydrogen-Ion Concentration; Hydrolysis; Peptides; Proteins; Pyridines; Sulfhydryl Compounds | 1991 |
Formation of a dehydroalanyl residue from S-benzylcysteine upon HF cleavage of a [Sar1, Cys8]-angiotensin II peptide resin.
Topics: Alanine; Cysteine; Hydrofluoric Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Resins, Synthetic | 1991 |
Synthetic and conformational studies on dehydroalanine-containing model peptides.
Topics: Alanine; Circular Dichroism; Dipeptides; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Protein Conformation; Spectrophotometry, Infrared | 1990 |
Location of dehydroalanine residues in the amino acid sequence of bovine thyroglobulin. Identification of "donor" tyrosine sites for hormonogenesis in thyroglobulin.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Molecular Sequence Data; Monoiodotyrosine; Peptide Fragments; Phenylthiohydantoin; Serine Endopeptidases; Thyroglobulin | 1990 |
Studies of peptide antibiotics. XLVI. Syntheses of gramicidin S analogs containing D-alpha,beta-diaminopropionic acid or alpha,beta-dehydroalanine.
Topics: Alanine; beta-Alanine; Gram-Negative Bacteria; Gram-Positive Bacteria; Gramicidin; Hydrogenation; Structure-Activity Relationship | 1985 |
Analogues of luteinizing hormone-releasing hormone (LH-RH) containing dehydroalanine in 6th position.
Topics: Alanine; Chorionic Gonadotropin; Female; Gonadotropin-Releasing Hormone; Humans; Indicators and Reagents; Placenta; Pregnancy; Protein Conformation; Structure-Activity Relationship | 1988 |
Colorimetry of dehydroalanine residues preserved as 'lost side chains' in thyroglobulin.
Topics: Alanine; Aniline Compounds; Colorimetry; Humans; Thyroglobulin; Thyroxine; Triiodothyronine | 1988 |
Thyroid hormonogenesis. Identification of a sequence containing iodophenyl donor site(s) in calf thyroglobulin.
Topics: Alanine; Animals; Binding Sites; Cattle; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Succinimides; Thyroglobulin; Thyroid Gland | 1987 |
Presence and quantity of dehydroalanine in histidine ammonia-lyase from Pseudomonas putida.
Topics: Alanine; Ammonia-Lyases; Binding Sites; Catalysis; Cyanides; Dimethyl Suberimidate; Histidine Ammonia-Lyase; Macromolecular Substances; Molecular Weight; Peptide Fragments; Pseudomonas; Serine; Structure-Activity Relationship | 1985 |
Studies of peptide antibiotics. XLIII. Syntheses of gramicidin S analogs containing D-serine or dehydroalanine in place of D-phenylalanine and asymmetric hydrogenation of the dehydroalanine residue.
Topics: Alanine; Bacteria; Gramicidin; Indicators and Reagents; Optical Rotation; Phenylalanine; Serine; Structure-Activity Relationship | 1983 |
The formation of dehydroalanine residues in alkali-treated insulin and oxidized glutathione. A nuclear-magnetic-resonance study.
Topics: Alanine; Chemical Phenomena; Chemistry; Glutathione; Insulin; Magnetic Resonance Spectroscopy; Models, Chemical; Sodium Hydroxide | 1983 |
Transformation of dehydroalanine residues in casein to S-beta-(2-pyridylethyl)-L-cysteine side chains.
Topics: Acetylation; Alanine; Amino Acids; Caseins; Cysteine; Indicators and Reagents; Pyridines | 1982 |
Formation of dehydroalanine residues during thyroid hormone synthesis in thyroglobulin.
Topics: Alanine; Amino Acids; Animals; Humans; Iodide Peroxidase; Peroxidases; Swine; Thyroglobulin; Thyroid Gland; Thyroxine; Triiodothyronine | 1980 |
The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.
Topics: Alanine; Amino Acid Sequence; Bacterial Toxins; Base Sequence; Cyanobacteria; Cysteine; Humans; Iodine Radioisotopes; Isotope Labeling; Microcystins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Binding; Protein Phosphatase 1 | 1995 |
A cassette vector for protein engineering the lantibiotic nisin.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Genetic Vectors; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Nisin; Plasmids; Protein Engineering | 1995 |
The mechanism of action of phenylalanine ammonia-lyase: the role of prosthetic dehydroalanine.
Topics: Alanine; Base Sequence; Borohydrides; Catalysis; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phenylalanine Ammonia-Lyase; Recombinant Proteins; Substrate Specificity; Tyrosine | 1995 |
The role of dehydro-alanine in the design of peptides.
Topics: Alanine; Amino Acid Sequence; Drug Design; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation; Thermodynamics | 1995 |
A quantum-mechanical study of the chain-length dependent stability of the extended and 3(10)-helix conformations in dehydroalanine oligopeptides.
Topics: Alanine; Drug Stability; Models, Chemical; Molecular Structure; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Quantum Theory; Thermodynamics | 1994 |
Histidine ammonia-lyase mutant S143C is posttranslationally converted into fully active wild-type enzyme. Evidence for serine 143 to be the precursor of active site dehydroalanine.
Topics: Alanine; Base Sequence; Cysteine; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Precursors; Protein Processing, Post-Translational; Pseudomonas putida; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 1994 |
Use of a dehydroalanine-containing peptide as an efficient inhibitor of tripeptidyl peptidase II.
Topics: Alanine; Amino Acid Sequence; Aminopeptidases; Animals; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Erythrocytes; Kinetics; Liver; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Phosphopeptides; Protease Inhibitors; Rats; Serine Endopeptidases | 1994 |
Serine-202 is the putative precursor of the active site dehydroalanine of phenylalanine ammonia lyase. Site-directed mutagenesis studies on the enzyme from parsley (Petroselinum crispum L.).
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; DNA; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine Ammonia-Lyase; Plants; Sequence Homology, Amino Acid; Serine | 1994 |
Sequence analysis of dehydroamino acid-containing peptides.
Topics: Alanine; Amino Acid Sequence; Aminobutyrates; Molecular Sequence Data; Peptides | 1994 |
Identification of serine-143 as the most likely precursor of dehydroalanine in the active site of histidine ammonia-lyase. A study of the overexpressed enzyme by site-directed mutagenesis.
Topics: Alanine; Base Sequence; Binding Sites; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pseudomonas putida; Recombinant Proteins; Serine | 1994 |
A conformational study of the dehydroalanine: dipeptide and homopolypeptide.
Topics: Alanine; Dipeptides; Peptides; Protein Conformation; Thermodynamics | 1993 |
Identification of the free radical formed by addition of hydroxyl radical to dehydroalanine compounds.
Topics: Alanine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Molecular Structure | 1993 |
Effect of the environment and role of the pi-pi stacking interactions in the stabilization of the 3(10)-helix conformation in dehydroalanine oligopeptides.
Topics: Alanine; Crystallization; Drug Stability; Electrochemistry; Models, Molecular; Molecular Structure; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Thermodynamics | 1995 |
Characterization of the covalent binding of thiostrepton to a thiostrepton-induced protein from Streptomyces lividans.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Thin Layer; Cysteine; Electrophoresis, Polyacrylamide Gel; Mass Spectrometry; Molecular Sequence Data; Peptide Mapping; Protein Binding; Streptomyces; Thiostrepton; Trans-Activators | 1996 |
Formation of the alpha-aminoacrylate immediate limits the overall reaction catalyzed by O-acetylserine sulfhydrylase.
Topics: Alanine; Catalysis; Cysteine Synthase; Kinetics; Salmonella typhimurium; Schiff Bases; Spectrophotometry, Ultraviolet | 1996 |
Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
Topics: Alanine; Circular Dichroism; Cysteine Synthase; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pyridoxal Phosphate; Salmonella typhimurium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1996 |
Conformational investigation of alpha,beta-dehydropeptides. VII. Conformation of Ac-Pro-deltaAla-NHCH3 and Ac-Pro-(E)-deltaAbu-NHCH3: comparison with (Z)-substituted alpha,beta-dehydropeptides.
Topics: Alanine; Circular Dichroism; Dipeptides; Magnetic Resonance Spectroscopy; Proline; Protein Structure, Secondary; Solvents; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; X-Ray Diffraction | 1996 |
Loop closure and intersubunit communication in tryptophan synthase.
Topics: Alanine; Allosteric Site; Crystallography, X-Ray; Enzyme Activation; Ligands; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Serine; Structure-Activity Relationship; Tryptophan Synthase | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Topics: Alanine; Catalysis; Crystallization; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Microspectrophotometry; Models, Chemical; Salmonella typhimurium; Serine; Sodium Azide; Structure-Activity Relationship | 1998 |
Plasticity of the tryptophan synthase active site probed by 31P NMR spectroscopy.
Topics: Alanine; Binding Sites; Catalysis; Glycine; Hydrogen-Ion Concentration; Indoles; Magnetic Resonance Spectroscopy; Molecular Probes; Phosphorus Isotopes; Protein Conformation; Sodium; Tryptophan Synthase | 1998 |
A novel super-potent neurokinin A receptor antagonist containing dehydroalanine.
Topics: Alanine; Amino Acid Sequence; Animals; Male; Models, Molecular; Molecular Structure; Peptides, Cyclic; Protein Conformation; Rats; Receptors, Neurokinin-2; Structure-Activity Relationship; Vas Deferens | 1998 |
A dehydroalanyl residue can capture the 5'-deoxyadenosyl radical generated from S-adenosylmethionine by pyruvate formate-lyase-activating enzyme.
Topics: Acetyltransferases; Alanine; Amino Acid Sequence; Deoxyadenosines; Enzymes; Escherichia coli; Free Radicals; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oligopeptides; Peptide Fragments; S-Adenosylmethionine | 1999 |
Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile.
Topics: Alanine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Energy Transfer; Histidine Ammonia-Lyase; Models, Molecular; Peptides; Protein Folding; Protein Structure, Secondary; Pseudomonas putida; Serine | 1999 |
Broad spectrum thiopeptide recognition specificity of the Streptomyces lividans TipAL protein and its role in regulating gene expression.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Gene Expression Regulation, Bacterial; Mass Spectrometry; Molecular Sequence Data; Peptides; Protein Conformation; Streptomyces; Trans-Activators | 1999 |
Behaviour of dehydroalanine derivatives under hydrazinolysis conditions. Possible relevance to glycoprotein hydrazinolysis.
Topics: Alanine; Chemistry, Organic; Glycoproteins; Hydrazines; Magnetic Resonance Spectroscopy; Organic Chemistry Phenomena | 1999 |
Tritium secondary kinetic isotope effect on phenylalanine ammonia-lyase-catalyzed reaction.
Topics: Alanine; Catalytic Domain; Deuterium; Kinetics; Models, Chemical; Phenylalanine Ammonia-Lyase; Rhodotorula; Substrate Specificity; Tritium | 1999 |
Effect of pH and monovalent cations on the formation of quinonoid intermediates of the tryptophan synthase alpha(2)beta(2) complex in solution and in the crystal.
Topics: Alanine; beta-MSH; Crystallization; Hydrogen-Ion Concentration; Protein Conformation; Quinones; Sodium; Tryptophan Synthase | 2000 |
Structural and conformational properties of (Z)-beta-(1-naphthyl)- dehydroalanine residue.
Topics: Alanine; Crystallography, X-Ray; Dipeptides; Indicators and Reagents; Models, Molecular; Molecular Conformation; Oligopeptides; Protein Conformation; Structure-Activity Relationship | 2001 |
Facile chemoselective synthesis of dehydroalanine-containing peptides.
Topics: Alanine; Oxidation-Reduction; Peptides; Selenocysteine; Stereoisomerism | 2000 |
Synthesis of tetrapeptide p-nitrophenylanilides containing dehydroalanine and dehydrophenylalanine and their influence on cathepsin C activity.
Topics: Alanine; Amino Acids; Anilides; Animals; Cathepsin C; Cattle; Magnetic Resonance Spectroscopy; Models, Chemical; Oligopeptides; Phenylalanine; Spleen | 2001 |
Convergent synthesis of peptide conjugates using dehydroalanines for chemoselective ligations.
Topics: Alanine; Ligation; Models, Chemical; Peptide Biosynthesis; Peptides; Protein Prenylation; Sulfhydryl Compounds; Thioglycosides | 2001 |
MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Caseins; Chromatography, High Pressure Liquid; Chymosin; Glycosylation; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2001 |
The conformation of dehydroalanine in short homopeptides: molecular dynamics simulations of a 6-residue chain.
Topics: Alanine; Computer Simulation; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Oligopeptides; Protein Conformation; Quantum Theory; Thermodynamics | 2002 |
Dehydroalanine-based inhibition of a peptide epimerase from spider venom.
Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Amino Acids; Animals; Catalysis; Hydrochloric Acid; Inhibitory Concentration 50; Molecular Mimicry; Peptides; Polyamines; Ribosomes; Serine; Spider Venoms; Spiders; Stereoisomerism; Structure-Activity Relationship | 2002 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Involvement of dehydroalanine and dehydrobutyrine in the addition of glutathione to nisin.
Topics: Alanine; Amino Acid Sequence; Aminobutyrates; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Food Preservatives; Glutathione; Mass Spectrometry; Molecular Sequence Data; Nisin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Loss of selenium from selenoproteins: conversion of selenocysteine to dehydroalanine in vitro.
Topics: Alanine; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Glutathione Peroxidase; Molecular Sequence Data; Proteins; Rats; Selenium; Selenocysteine; Selenoprotein P; Selenoproteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis.
Topics: Alanine; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Binding Sites; Chromatography, High Pressure Liquid; Enediynes; Imidazoles; Intramolecular Transferases; Streptomyces | 2003 |
ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE.
Topics: Alanine; Chymotrypsin; Proteins; Research; Serine | 1963 |
Oligosaccharide-peptide ligation of glycosyl thiolates with dehydropeptides: synthesis of S-linked mucin-related glycopeptide conjugates.
Topics: Alanine; Antigens, Tumor-Associated, Carbohydrate; Cysteine; Glycopeptides; Glycosylation; Mucins; Oligosaccharides; Peptides; Stereoisomerism; Sulfhydryl Compounds; Thiogalactosides | 2003 |
Dehydroalanine crosslinks in human lens.
Topics: Adult; Aged; Aging; Alanine; Cataract; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Crystallins; Dipeptides; Humans; Lens, Crystalline; Lysinoalanine; Middle Aged; Solubility; Sulfides | 2004 |
Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics.
Topics: Alanine; Chromatography, Liquid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Mimicry; Thiostrepton | 2005 |
Glutathionylation of lens proteins through the formation of thioether bond.
Topics: Aging; Alanine; Animals; Cattle; Crystallins; Glutathione; Glutathione Disulfide; Humans; Lens, Crystalline; Solutions; Sulfides | 2005 |
Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex.
Topics: Alanine; Allosteric Regulation; Bacteria; Benzimidazoles; Catalytic Domain; Glycerophosphates; Indoles; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Spectrophotometry; Tryptophan; Tryptophan Synthase | 2005 |
Ribosomal synthesis of dehydroalanine-containing peptides.
Topics: Alanine; Escherichia coli; Lysine; Organoselenium Compounds; Peptides, Cyclic; Protein Biosynthesis; Protein Conformation; Ribosomes; RNA, Messenger | 2006 |
Novel N-acyl dehydroalanine derivatives as antioxidants: studies on rat liver lipid peroxidation levels and DPPH free radical scavenging activity.
Topics: Alanine; Animals; Antioxidants; Biphenyl Compounds; Free Radical Scavengers; Hydrazines; Lipid Peroxidation; Liver; Male; Picrates; Rats; Rats, Wistar; Structure-Activity Relationship | 2006 |
Synthesis of low-hemolytic antimicrobial dehydropeptides based on gramicidin s.
Topics: Alanine; Anti-Bacterial Agents; Circular Dichroism; Gram-Positive Bacteria; Gramicidin; Hemolysis; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Structure-Activity Relationship | 2006 |
Dehydroalanine-containing peptides: preparation from phenylselenocysteine and utility in convergent ligation strategies.
Topics: Alanine; Glycopeptides; Peptides; Research Design; Selenocysteine | 2006 |
Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex.
Topics: Alanine; Binding Sites; Catalysis; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Cysteine Synthase; Enzyme Inhibitors; Enzymes; Lysine; Models, Chemical; Models, Molecular; Mycobacterium tuberculosis; Protein Conformation; Protein Structure, Tertiary | 2007 |
A biosynthetic route to dehydroalanine-containing proteins.
Topics: Alanine; Proteins | 2007 |
Conversion of nocathiacin I to nocathiacin acid by a mild and selective cleavage of dehydroalanine.
Topics: Alanine; Carboxylic Acids; Intercellular Signaling Peptides and Proteins; Peptides; Peptides, Cyclic; Thiazoles | 2007 |
Testing beta-helix terminal coils stability by targeted substitutions with non-proteogenic amino acids: a molecular dynamics study.
Topics: Alanine; Amino Acid Motifs; Amino Acids; Carbon; Escherichia coli; Glycine; Models, Chemical; Models, Molecular; Molecular Conformation; Nanotechnology; Nanotubes; Oligopeptides; Peptides; Protein Structure, Secondary | 2007 |
Combined effect of the DeltaPhe or DeltaAla residue and the p-nitroanilide group on a didehydropeptides conformation.
Topics: Alanine; Amides; Circular Dichroism; Crystallography; Dipeptides; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Phenylalanine; Protein Conformation; Spectroscopy, Fourier Transform Infrared | 2008 |
Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine.
Topics: Alanine; Amines; Computer Simulation; Cyclization; Cyclopentanes; Guanidines; Models, Chemical; Models, Molecular; Molecular Conformation; Quantum Theory; Spiro Compounds; Stereoisomerism | 2008 |
Identifying the presence of a disulfide linkage in peptides by the selective elimination of hydrogen disulfide from collisionally activated alkali and alkaline earth metal complexes.
Topics: Alanine; Animals; Cations; Cysteine; Disulfides; Gastric Mucosa; Hydrogen Sulfide; Insulin; Intestinal Mucosa; Metals; Models, Chemical; Peptides; Spectrometry, Mass, Electrospray Ionization; Swine; Vasopressins | 2008 |
Dehydroalanine derived from cysteine is a common post-translational modification in human serum albumin.
Topics: Alanine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Humans; Models, Chemical; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2008 |
Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.
Topics: Alanine; Alkylation; Cysteine; Models, Molecular; Molecular Structure; Protein Processing, Post-Translational; Proteins; Spectrometry, Mass, Electrospray Ionization; Surface Properties | 2008 |
Natural occurrence of microcystin synthetase deletion mutants capable of producing microcystins in strains of the genus Anabaena (Cyanobacteria).
Topics: Alanine; Anabaena; Bacterial Proteins; DNA, Bacterial; Microcystins; Molecular Sequence Data; Molecular Structure; Peptide Synthases; Phylogeny; Polymerase Chain Reaction; Protein Structure, Tertiary; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology; Serine; Water Microbiology | 2008 |
The importance of the leader sequence for directing lanthionine formation in lacticin 481.
Topics: 5' Untranslated Regions; Alanine; Amino Acid Sequence; Aminobutyrates; Bacteriocins; Conserved Sequence; DNA Primers; Enzymes; Gene Expression; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sulfides | 2008 |
Dehydroalanine and lysinoalanine in thermolyzed casein do not promote colon cancer in the rat.
Topics: Alanine; Animals; Azoxymethane; Carcinogenicity Tests; Caseins; Cheese; Colonic Neoplasms; Diet; Feces; Female; Hot Temperature; Intestinal Mucosa; Lysinoalanine; Rats; Rats, Inbred F344 | 2008 |
Complete covalent structure of nisin Q, new natural nisin variant, containing post-translationally modified amino acids.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Bacteriocins; Magnetic Resonance Spectroscopy; Molecular Structure; Nisin; Protein Processing, Post-Translational; Sulfides | 2008 |
Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1.
Topics: Alanine; Animals; Antineoplastic Agents, Alkylating; Busulfan; Cell Line, Tumor; Glioma; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Liver; Rats | 2008 |
The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity.
Topics: Alanine; Catalytic Domain; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Hydrogen Peroxide; Models, Chemical; Mycobacterium tuberculosis; Oxidative Stress; Protein Conformation; Sulfur | 2009 |
Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.
Topics: Alanine; Amyloid beta-Peptides; Drug Design; Mass Spectrometry; Molecular Structure; Oligopeptides; Peptide Fragments | 2009 |
Characterization of alkali induced formation of lanthionine, trisulfides, and tetrasulfides from peptide disulfides using negative ion mass spectrometry.
Topics: Alanine; Glutathione Disulfide; Peptides, Cyclic; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Sulfides | 2009 |
Two novel bovine somatotropin species generated from a common dehydroalanine intermediate.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Chromatography, Ion Exchange; Growth Hormone; Hydrogen-Ion Concentration; Lysinoalanine; Molecular Sequence Data; Peptide Mapping; Protein Conformation; Protein Multimerization; Sequence Analysis, Protein; Sulfides; Tandem Mass Spectrometry | 2009 |
Chapter 21. In vitro studies of lantibiotic biosynthesis.
Topics: Alanine; Aminobutyrates; Bacteriocins; Molecular Structure; Sulfides | 2009 |
Comparative effect of N-substituted dehydroamino acids and alpha-tocopherol on rat liver lipid peroxidation activities.
Topics: Alanine; alpha-Tocopherol; Animals; Antioxidants; Lipid Peroxidation; Liver; Molecular Structure; Rats | 2009 |
Facile formation of dehydroalanine from S-nitrosocysteines.
Topics: Alanine; Catalysis; Cysteine; Phosphines; S-Nitrosothiols | 2009 |
Selective reduction of C=C double bonds in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of microcystins.
Topics: 2-Naphthylamine; Alanine; Aminobutyrates; Microcystins; Molecular Structure; Oxidation-Reduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Irreversible inactivation of glutathione peroxidase 1 and reversible inactivation of peroxiredoxin II by H2O2 in red blood cells.
Topics: Alanine; Biocatalysis; Catalytic Domain; Erythrocytes; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Hydrogen Peroxide; Mass Spectrometry; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Peroxiredoxins | 2010 |
An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.
Topics: Alanine; Carbonates; gamma-Aminobutyric Acid; Peptides; Quaternary Ammonium Compounds; Serine; Threonine | 2010 |
Synthesis and electrochemical behaviour of beta-halodehydroamino acid derivatives.
Topics: Alanine; Amino Acids; Electrochemical Techniques; Halogenation; Stereoisomerism; Succinimides; Tosyl Compounds | 2010 |
Synthesis and biological characterization of argyrin F.
Topics: Alanine; Antineoplastic Agents; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Kinetics; Peptide Hydrolases; Peptides, Cyclic; Protease Inhibitors; Proteasome Inhibitors; RNA Interference; RNA, Small Interfering; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Tryptophan | 2010 |
Blot-based detection of dehydroalanine-containing glutathione peroxidase with the use of biotin-conjugated cysteamine.
Topics: Alanine; Animals; Biotin; Cells, Cultured; Cysteamine; Glutathione Peroxidase; Humans; Immunoconjugates; Immunoprecipitation; Streptavidin | 2010 |
Novel oxidative modifications in redox-active cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Catalytic Domain; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); HEK293 Cells; Humans; Mass Spectrometry; Mice; Mitochondrial Proteins; Molecular Sequence Data; Mutant Proteins; Nucleoside-Diphosphate Kinase; Oxidation-Reduction; Peptides; Peroxiredoxin VI; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfenic Acids; Sulfinic Acids | 2011 |
Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein.
Topics: Alanine; Animals; Electrophoresis, Polyacrylamide Gel; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hydrogen Peroxide; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Selenocysteine; Superoxide Dismutase; Superoxide Dismutase-1; tert-Butylhydroperoxide | 2011 |
Artificial lantipeptides from in vitro translations.
Topics: Alanine; Amino Acid Sequence; Aminobutyrates; Cross-Linking Reagents; Lysine; Molecular Sequence Data; Organoselenium Compounds; Peptide Biosynthesis; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides | 2011 |
A "tag-and-modify" approach to site-selective protein modification.
Topics: Alanine; Alkynes; Azides; Catalysis; Copper; Cysteine; Disulfides; Free Radicals; Glycosylation; Palladium; Protein Prenylation; Proteins; Ruthenium | 2011 |
Cross-linking of wheat gluten proteins during production of hard pretzels.
Topics: Alanine; Chromatography, Ion Exchange; Cross-Linking Reagents; Cysteine; Cystine; Food Handling; Food Technology; Glutens; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Maillard Reaction; Reducing Agents; Sodium Dodecyl Sulfate; Sodium Hydroxide; Sulfides; Triticum | 2012 |
Reversible hydrogen transfer reactions of cysteine thiyl radicals in peptides: the conversion of cysteine into dehydroalanine and alanine, and of alanine into dehydroalanine.
Topics: Alanine; Amino Acid Sequence; Cysteine; Deuterium Exchange Measurement; Deuterium Oxide; Free Radicals; Hydrogen; Hydrogen-Ion Concentration; Peptides; Photolysis; Thermodynamics | 2011 |
Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics.
Topics: Alanine; Artifacts; Cells, Cultured; Cysteine; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Metabolomics; Mimosine; Skin | 2011 |
Using the same organocatalyst for asymmetric synthesis of both enantiomers of glutamic acid-derived Ni(II) complexes via 1,4-additions of achiral glycine and dehydroalanine Schiff base Ni(II) complexes.
Topics: 1-Carboxyglutamic Acid; Alanine; Catalysis; Glutamic Acid; Glycine; Naphthols; Nickel; Schiff Bases; Stereoisomerism | 2012 |
Conversion of cysteine into dehydroalanine enables access to synthetic histones bearing diverse post-translational modifications.
Topics: Alanine; Alkylation; Cysteine; Histones; Humans; Models, Molecular; Protein Conformation; Protein Processing, Post-Translational | 2012 |
High yielding synthesis of N-ethyl dehydroamino acids.
Topics: Alanine; Alkylation; Amino Acids; Borates; Butanols; Dipeptides; Esters; Water | 2012 |
Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite.
Topics: Alanine; Antioxidants; Biocatalysis; Busulfan; Chromatography, Liquid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Glutathione Transferase; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Pyridines; Tandem Mass Spectrometry | 2012 |
Catalytic asymmetric construction of quaternary α-amino acid containing pyrrolidines through 1,3-dipolar cycloaddition of azomethine ylides to α-aminoacrylates.
Topics: Alanine; Amino Acids; Azo Compounds; Catalysis; Cycloaddition Reaction; Dicarboxylic Acids; Molecular Structure; Pyrrolidines; Stereoisomerism; Thiosemicarbazones | 2013 |
Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway.
Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Dipeptides; Genes, Bacterial; Peptidyl Transferases; RNA, Bacterial; RNA, Transfer; Streptomyces | 2013 |
Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition.
Topics: Alanine; Endopeptidase Clp; Models, Molecular; Molecular Structure; Protease Inhibitors; Structure-Activity Relationship | 2014 |
Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.
Topics: Adult; Aged, 80 and over; Alanine; Amino Acid Sequence; Aminobutyrates; Cell Nucleus; Cross-Linking Reagents; Crystallins; Glutathione; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry; Threonine; Time Factors | 2014 |
Dehydroalanine-based diubiquitin activity probes.
Topics: Alanine; Amino Acid Sequence; Humans; Lysine; Models, Molecular; Molecular Structure; Protein Conformation; Ubiquitin-Specific Proteases; Ubiquitins | 2014 |
S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-Tn antigen mimic.
Topics: Alanine; Antigens, Tumor-Associated, Carbohydrate; Carbohydrates; Cysteine; Diamide; Glycosylation; Models, Molecular; Molecular Conformation | 2014 |
Conformational properties of oxazole-amino acids: effect of the intramolecular N-H···N hydrogen bond.
Topics: Alanine; Amino Acids; Aminobutyrates; Hydrogen; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Theoretical; Molecular Conformation; Nitrogen; Oxazoles; Solvents; Spectroscopy, Fourier Transform Infrared; Surface Properties; Thermodynamics | 2014 |
A comparison of reversible versus irreversible protein glutathionylation.
Topics: Alanine; Aminobutyrates; Enzymes; Gene Expression Regulation, Neoplastic; Glutaredoxins; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Lens, Crystalline; Neoplasms; Peptides; Proteins; Reactive Oxygen Species; Signal Transduction | 2014 |
Diverse functionalization of Aurora-A kinase at specified surface and buried sites by native chemical modification.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aurora Kinase A; Binding Sites; Catalytic Domain; Cysteine; Escherichia coli; Models, Molecular; Molecular Sequence Data; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Structure, Secondary; Sulfhydryl Compounds | 2014 |
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans.
Topics: Alanine; Kinetics; Models, Chemical; Molecular Structure; Oligopeptides; Oxazolidinones; Receptors, Opioid, mu; Stereoisomerism; Tryptophan | 2014 |
Synthesis of nisin AB dicarba analogs using ring-closing metathesis: influence of sp(3) versus sp(2) hybridization of the α-carbon atom of residues dehydrobutyrine-2 and dehydroalanine-5 on the lipid II binding affinity.
Topics: Alanine; Amino Acid Sequence; Aminobutyrates; Anti-Bacterial Agents; Molecular Docking Simulation; Molecular Sequence Data; Nisin; Unilamellar Liposomes; Uridine Diphosphate N-Acetylmuramic Acid | 2015 |
Ugi-derived dehydroalanines as a pivotal template in the diversity oriented synthesis of aza-polyheterocycles.
Topics: Alanine; Benzylamines; Catalysis; Indoles; Isoquinolines; Palladium; Pyrroles | 2015 |
Phosphoserine Lyase Deoxyribozymes: DNA-Catalyzed Formation of Dehydroalanine Residues in Peptides.
Topics: Alanine; ATP Citrate (pro-S)-Lyase; Biocatalysis; Cyclization; DNA, Catalytic; Peptides | 2015 |
Chemical generation and modification of peptides containing multiple dehydroalanines.
Topics: Alanine; Amino Acid Sequence; Chromatography, Liquid; Humans; Kallikreins; Molecular Structure; Peptides; Stereoisomerism; Valerates | 2015 |
Post-translational Introduction of D-Alanine into Ribosomally Synthesized Peptides by the Dehydroalanine Reductase NpnJ.
Topics: Alanine; Oxidoreductases; Peptides; Protein Processing, Post-Translational; Ribosomes | 2015 |
Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers.
Topics: Alanine; Cell Line, Tumor; Circular Dichroism; Drug Carriers; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Microscopy, Electron, Transmission; Models, Theoretical; Naphthalenes; Naproxen; Phenylalanine; Rheology; Tryptophan | 2015 |
Derivatisable Cyanobactin Analogues: A Semisynthetic Approach.
Topics: Alanine; Amino Acid Sequence; Carbocyanines; Click Chemistry; Copper; Cycloaddition Reaction; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Microscopy, Fluorescence; Peptides, Cyclic | 2015 |
Michael addition of dehydroalanine-containing MAPK peptides to catalytic lysine inhibits the activity of phosphothreonine lyase.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Biocatalysis; Enzyme Inhibitors; Lyases; Lysine; Mitogen-Activated Protein Kinases; Peptidomimetics; Phosphorylation; Phosphothreonine | 2015 |
Insights into the Biosynthesis of Dehydroalanines in Goadsporin.
Topics: Actinobacteria; Alanine; Bacterial Proteins; Chromatography, High Pressure Liquid; Hydro-Lyases; Intercellular Signaling Peptides and Proteins; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Streptomyces | 2016 |
Identification of lanthionine and lysinoalanine in heat-treated wheat gliadin and bovine serum albumin using tandem mass spectrometry with higher-energy collisional dissociation.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Cysteine; Cystine; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Proteolysis; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Triticum; Trypsin | 2016 |
1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides.
Topics: Alanine; Azides; Azo Compounds; Cycloaddition Reaction; Molecular Structure | 2016 |
Asymmetric Synthesis of N-Boc-(R)-Silaproline via Rh-Catalyzed Intramolecular Hydrosilylation of Dehydroalanine and Continuous Flow N-Alkylation.
Topics: Alanine; Alkylation; Catalysis; Cyclization; Organosilicon Compounds; Proline | 2016 |
Protein ubiquitination via dehydroalanine: development and insights into the diastereoselective 1,4-addition step.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Models, Molecular; Protein Conformation; Stereoisomerism; Substrate Specificity; Ubiquitin; Ubiquitination | 2016 |
Selective Gas-Phase Oxidation and Localization of Alkylated Cysteine Residues in Polypeptide Ions via Ion/Ion Chemistry.
Topics: Alanine; Alkylation; Cysteine; Gases; Ions; Mass Spectrometry; Oxidation-Reduction; Peptides; Periodic Acid; Protein Processing, Post-Translational; Safrole | 2016 |
The dehydroalanine effect in the fragmentation of ions derived from polypeptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Disulfides; Ions; Oxidation-Reduction; Peptide Fragments; Peptides; Protons; Spectrometry, Mass, Electrospray Ionization | 2016 |
The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins.
Topics: Alanine; Busulfan; Cysteine; Humans; Myeloablative Agonists; Sulfides; Tandem Mass Spectrometry | 2016 |
A chemical biology route to site-specific authentic protein modifications.
Topics: Acetylation; Alanine; Animals; Copper; Green Fluorescent Proteins; Histones; Iodides; Methylation; Phosphoserine; Protein Biosynthesis; Protein Engineering; Protein Processing, Post-Translational; Recombinant Proteins; Ubiquitin; Xenopus laevis; Xenopus Proteins; Zinc | 2016 |
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.
Topics: Alanine; Bromus; Carbon; Free Radicals; Genetic Code; Glycosylation; Iodine; Mutagenesis; Peptides; Protein Engineering; Protein Processing, Post-Translational; Proteins | 2016 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Glucagon-Like Peptide 1; Hydro-Lyases; Lactococcus lactis; Lysinoalanine; Membrane Proteins; Membrane Transport Proteins; Protein Processing, Post-Translational; SEC Translocation Channels; Serine; Substrate Specificity; Threonine | 2017 |
Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells.
Topics: Alanine; Aminobutyrates; Animals; Antibodies; Bacterial Proteins; Caco-2 Cells; Carbon-Oxygen Lyases; Cell Line; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Protein Binding; Proteomics; Shigella; Substrate Specificity; Threonine; Type III Secretion Systems | 2017 |
Addition of thiols to the double bond of dipeptide C-terminal dehydroalanine as a source of new inhibitors of cathepsin C.
Topics: Alanine; Animals; Binding Sites; Cathepsin C; Cattle; Cysteine Proteinase Inhibitors; Dipeptides; Kinetics; Models, Molecular; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Compounds | 2017 |
P450-Mediated Non-natural Cyclopropanation of Dehydroalanine-Containing Thiopeptides.
Topics: Alanine; Cytochrome P-450 Enzyme System; Peptides; Propane; Protein Processing, Post-Translational; Ribosomes; Sulfhydryl Compounds | 2017 |
Hotspots of age-related protein degradation: the importance of neighboring residues for the formation of non-disulfide crosslinks derived from cysteine.
Topics: Age Factors; Alanine; beta-Crystallin A Chain; Cysteine; Databases, Protein; Disulfides; Eye Proteins; Humans; Lens, Crystalline; Models, Molecular; Oligopeptides; Proteolysis; Tandem Mass Spectrometry | 2017 |
Substrate-Induced Facilitated Dissociation of the Competitive Inhibitor from the Active Site of O-Acetyl Serine Sulfhydrylase Reveals a Competitive-Allostery Mechanism.
Topics: Acetyl Coenzyme A; Alanine; Allosteric Regulation; Bacterial Proteins; Binding Sites; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Cysteine Synthase; Enzyme Inhibitors; Haemophilus influenzae; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Protein Interaction Domains and Motifs; Recombinant Proteins; Salmonella enterica; Serine; Serine O-Acetyltransferase | 2017 |
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation.
Topics: Alanine; Albumins; Amines; Animals; Annexin A5; Antibodies; Cell Death; Cell Line, Tumor; Cell Survival; Crizotinib; Disulfides; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Kinetics; Mice; Models, Molecular; Molecular Structure; Pyrazoles; Pyridines; Quantum Theory; Synaptotagmin I | 2017 |
DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione.
Topics: Alanine; Amino Acid Sequence; Crystallins; Dipeptides; Glutathione; Glutathione Disulfide; Humans; Lens, Crystalline; Lysine; Middle Aged; Molecular Structure; Peptides; Protein Conformation; Protein Processing, Post-Translational; Proteins; Tandem Mass Spectrometry; Young Adult | 2018 |
Activity-Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α-Globin-Modulating Deubiquitinase.
Topics: Alanine; alpha-Globins; Deubiquitinating Enzymes; Humans; Molecular Probes; Molecular Structure | 2018 |
Post-translational mutagenesis for installation of natural and unnatural amino acid side chains into recombinant proteins.
Topics: Alanine; Amino Acids; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Processing, Post-Translational; Recombinant Proteins | 2017 |
Quantification of thioether-linked glutathione modifications in human lens proteins.
Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult | 2018 |
Catalytic Modification of Dehydroalanine in Peptides and Proteins by Palladium-Mediated Cross-Coupling.
Topics: Alanine; Catalysis; Organometallic Compounds; Palladium; Peptides; Proteins; Water | 2018 |
Chemical Modification of Dehydrated Amino Acids in Natural Antimicrobial Peptides by Photoredox Catalysis.
Topics: Alanine; Aminobutyrates; Borates; Catalysis; Coordination Complexes; Iridium; Light; Nisin; Oxidation-Reduction; Photochemical Processes; Ruthenium; Thiostrepton | 2018 |
Catalytic Arylhydroxylation of Dehydroalanine in Continuous Flow for Simple Access to Unnatural Amino Acids.
Topics: Alanine; Amino Acids; Azo Compounds; Catalysis; Drug Design; Hydroxylation; Oxidation-Reduction; Stereoisomerism | 2018 |
Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Topics: Alanine; Anti-Bacterial Agents; Bacillus subtilis; Bacteriocins; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; DNA Mutational Analysis; Escherichia coli; Hydrolysis; Lysinoalanine; Molecular Dynamics Simulation; Mutation; Peptides; Protein Multimerization; Protein Processing, Post-Translational; Protein Structure, Secondary; Stereoisomerism; Streptomyces; Substrate Specificity | 2018 |
Different Routes to Ampholytic Polydehydroalanine: Orthogonal versus Simultaneous Deprotection.
Topics: Alanine; Buffers; Free Radicals; Molecular Structure; Polymerization; Polymers | 2019 |
Possible Mechanisms of Nonenzymatic Formation of Dehydroalanine Residue Catalyzed by Dihydrogen Phosphate Ion.
Topics: Alanine; Catalysis; Models, Molecular; Molecular Conformation; Phosphates; Stereoisomerism | 2019 |
Late-Stage Diversification of Phosphinic Dehydroalanine Pseudopeptides Based on a Giese-Type Radical C-Alkylation Strategy.
Topics: Alanine; Alkylation; Free Radicals; Molecular Structure; Peptides; Phosphinic Acids | 2019 |
Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins.
Topics: Alanine; Aminobutyrates; Models, Molecular; Protein Engineering; Protein Structure, Secondary | 2019 |
An activity-based probe developed by a sequential dehydroalanine formation strategy targets HECT E3 ubiquitin ligases.
Topics: Alanine; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Ubiquitin-Protein Ligases | 2019 |
Selective Modification of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) through Diels-Alder Cycloadditions on Dehydroalanine Residues.
Topics: Alanine; Cycloaddition Reaction; Peptides; Protein Processing, Post-Translational; Ribosomes | 2019 |
Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Topics: Alanine; Crystallography, X-Ray; Glutamic Acid; Hydro-Lyases; Nisin; Protein Domains; Recombinant Proteins; RNA, Transfer, Amino Acyl | 2019 |
Cobalt(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversification of Thiostrepton.
Topics: Alanine; Anti-Bacterial Agents; Catalysis; Cobalt; Humans; Thiostrepton | 2020 |
Gas-Phase Sequencing of Cyclotides: Introduction of Selective Ring Opening at Dehydroalanine via Ion/Ion Reaction.
Topics: Alanine; Amino Acids; Cyclotides; Gas Chromatography-Mass Spectrometry; Humans; Viola | 2019 |
Access to Unnatural α-Amino Acids via Visible-Light-Mediated Decarboxylative Conjugate Addition to Dehydroalanine.
Topics: Alanine; Amino Acids; Decarboxylation; Photochemical Processes | 2020 |
A Chemical Probe for Dehydrobutyrine.
Topics: Alanine; Amines; Aminobutyrates; Bacteria; Bacterial Infections; Biomarkers; Histones; Humans; Lyases; Phosphines; Phosphothreonine; Protein Processing, Post-Translational; Sulfhydryl Compounds | 2020 |
Cu(II)-Catalysed β-silylation of dehydroalanine residues in peptides and proteins.
Topics: Alanine; Catalysis; Copper; Molecular Conformation; Peptides; Proteins; Silanes | 2020 |
A Water-Soluble Iridium Photocatalyst for Chemical Modification of Dehydroalanines in Peptides and Proteins.
Topics: Alanine; Iridium; Proteins; Solubility; Water | 2021 |
Discovery and Biosynthetic Investigation of a New Antibacterial Dehydrated Non-Ribosomal Tripeptide.
Topics: Alanine; Aminobutyrates; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacterial Proteins; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Enterococcus faecium; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Peptide Biosynthesis, Nucleic Acid-Independent; Peptide Synthases; Stereoisomerism; Streptomyces | 2021 |
Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water.
Topics: Alanine; Catalysis; Cysteine; Kinetics; Nitriles; Origin of Life; Peptides; Serine | 2020 |
Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) via Cu
Topics: Alanine; Anti-Bacterial Agents; Boronic Acids; Catalysis; Copper; Enterococcus faecalis; Microbial Sensitivity Tests; Nisin; Protein Processing, Post-Translational; Ribosomes; Solubility; Staphylococcus aureus; Thiazoles; Thiostrepton | 2021 |
Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective
Topics: Alanine; Amino Acids; Catalysis; Stereoisomerism | 2021 |
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study.
Topics: Alanine; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2021 |
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome.
Topics: Alanine; Aminobutyrates; Animals; Antimicrobial Cationic Peptides; Female; Glutathione; HEK293 Cells; Humans; Male; MAP Kinase Kinase 1; Membrane Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Phosphate-Binding Proteins; Phosphorylation; Protein Domains; Proteome; Receptors, G-Protein-Coupled; Sulfides | 2021 |
Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid.
Topics: Alanine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cysteine; Models, Molecular; Protein Conformation; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Thiocyanates | 2021 |
Biocompatible Photoinduced Alkylation of Dehydroalanine for the Synthesis of Unnatural α-Amino Acids.
Topics: Alanine; Alkylation; Amino Acids; Peptides | 2021 |
Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate.
Topics: Alanine; Catalysis; Catalytic Domain; Crystallography, X-Ray; Indoles; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Pyridoxal Phosphate; Tryptophan Synthase | 2022 |
Efficient Enzymatic Incorporation of Dehydroalanine Based on SAMDI-Assisted Identification of Optimized Tags for OspF/SpvC.
Topics: Alanine; Lyases; Phosphothreonine; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2022 |
Poly(dehydroalanine): Synthesis, Properties, and Functional Diversification of a Fluorescent Polypeptide.
Topics: Alanine; Cysteine; Peptides; Sulfhydryl Compounds | 2022 |
Phosphine addition to dehydroalanine for peptide modification.
Topics: Alanine; Amino Acid Sequence; Phosphines; Sulfhydryl Compounds | 2022 |
Nonenzymatic Asparagine Motif Synthesis by Photoredox-Catalyzed Carbamoylation of Dehydroalanine.
Topics: Alanine; Amides; Asparagine; Catalysis; Peptides; Protein Carbamylation | 2022 |
Synthesis of Tetrapeptides Containing Dehydroalanine, Dehydrophenylalanine and Oxazole as Building Blocks for Construction of Foldamers and Bioinspired Catalysts.
Topics: Alanine; Oxazoles; Peptides; Phenylalanine | 2022 |
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids.
Topics: Alanine; Alkylation; Amines; Amino Acids; Catalysis; Ketones; Peptides; Stereoisomerism; Thiourea | 2022 |
Sequential Heck Cross-Coupling and Hydrothiolation Reactions Taking Place in the Ligand Sphere of a Chiral Dehydroalanine Ni(II) Complex: Asymmetric Route to β-Aryl Substituted Cysteines.
Topics: Alanine; Catalysis; Cysteine; Iodides; Ligands | 2022 |
Modulable Photocatalyzed Strategies for the Synthesis of α-
Topics: Alanine | 2023 |
Visible-Light Mediated Deoxygenation of Carboxylic Acid for Late-Stage Peptide Modification Targeting Dehydroalanine.
Topics: Alanine; Carboxylic Acids; Peptides; Photochemistry | 2023 |