alanine has been researched along with camptothecin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bjornsti, MA; Fertala, J; Knab, AM | 1 |
| Beavis, RC; Berman, Y; Devi, LA; Newcomb, EW; Reed, JC; Thomas, A; Wood, DE | 1 |
| Amatruda, JF; Benedetti, P; Bjornsti, MA; Butler, RH; Fiorani, P; Silvestri, A | 1 |
| Benedetti, P; Bruselles, A; Chillemi, G; Desideri, A; Falconi, M; Fiorani, P | 1 |
| Chao, P; Deshmukh, M; Gao, D; Kutscher, HL; Sinko, PJ | 1 |
| Jensen, BV; Larsen, FO; Nielsen, DL; Palshof, JA; Pfeiffer, P | 1 |
1 review(s) available for alanine and camptothecin
| Article | Year |
|---|---|
A systematic review of salvage therapy to patients with metastatic colorectal cancer previously treated with fluorouracil, oxaliplatin and irinotecan +/- targeted therapy.
Topics: Alanine; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Databases, Factual; ErbB Receptors; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Molecular Targeted Therapy; Organoplatinum Compounds; Oxaliplatin; Phenylurea Compounds; PubMed; Pyridines; Retreatment; Salvage Therapy; Treatment Failure; Triazines | 2014 |
5 other study(ies) available for alanine and camptothecin
| Article | Year |
|---|---|
A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.
Topics: Alanine; Arginine; Base Sequence; Binding Sites; Camptothecin; Cloning, Molecular; DNA; DNA Topoisomerases, Type I; Drug Resistance; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Tyrosine | 1995 |
Bax cleavage is mediated by calpain during drug-induced apoptosis.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Binding Sites; Calpain; Camptothecin; Cell Death; Cell Extracts; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; HL-60 Cells; Humans; Hydrolysis; Leucine; Molecular Sequence Data; Mutation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Substrate Specificity | 1998 |
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.
Topics: Alanine; Amino Acid Substitution; Camptothecin; Catalysis; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Enzyme Stability; Glycine; Humans; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Threonine; Topoisomerase I Inhibitors; Transfection | 1999 |
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
Topics: Alanine; Binding Sites; Camptothecin; Catalysis; Cell Survival; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Humans; Ions; Kinetics; Models, Molecular; Mutation; Oligonucleotides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Time Factors; Tyrosine | 2003 |
A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.
Topics: Alanine; Aminobutyrates; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cell Survival; Esters; Glycine; Humans; Hydrolysis; Lung Neoplasms; Prodrugs; Tumor Cells, Cultured; Valine | 2010 |