alanine has been researched along with c(alpha)-formylglycine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 19 (57.58) | 29.6817 |
| 2010's | 5 (15.15) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Dierks, T; Schmidt, B; von Figura, K | 1 |
| Dierks, T; Miech, C; Schmidt, B; Selmer, T; von Figura, K | 1 |
| Dierks, T; Recksiek, M; Schmidt, B; Selmer, T; von Figura, K | 1 |
| Dierks, T; Lecca, MR; Schmidt, B; von Figura, K | 1 |
| Dierks, T; Hummerjohann, J; Kertesz, MA; Miech, C; Schmidt, B; von Figura, K | 1 |
| Dierks, T; Knaust, A; Schmidt, B; von Bülow, R; von Figura, K | 1 |
| Dierks, T; Lecca, MR; Schlotterhose, P; Schmidt, B; von Figura, K | 1 |
| Balleininger, M; Dierks, T; Miech, C; Schmidt, B; Szameit, C; von Figura, K | 1 |
| Malini, B; Potter, BV; Purohit, A; Reed, MJ; Woo, LL | 1 |
| Dierks, T; Schmidt, B; Usón, I; von Bülow, R; von Figura, K | 1 |
| Balleininger, M; Borissenko, LV; Dierks, T; Fey, J; Schmidt, B; von Figura, K | 1 |
| Dierks, T; Fang, Q; Marquordt, C; Peng, J; von Figura, K; Will, E | 1 |
| Myette, JR; Pojasek, K; Raman, R; Sasisekharan, R; Shriver, Z; Venkataraman, G | 1 |
| Dierks, T; Peng, J; Schmidt, B; von Figura, K | 1 |
| Baenziger, JU | 1 |
| Borissenko, LV; Dierks, T; Mariappan, M; Peng, J; Preusser, A; Schmidt, B; von Figura, K | 1 |
| Dierks, T; Landgrebe, J; Schmidt, B; von Figura, K | 1 |
| Balleininger, M; Dierks, T; Eiselt, N; Gande, SL; Mariappan, M; Preusser-Kunze, A; Schmidt, B; von Figura, K; Wenzel, D | 1 |
| Dickmanns, A; Dierks, T; Ficner, R; Mariappan, M; Preusser-Kunze, A; Rudolph, MG; Schmidt, B; von Figura, K | 1 |
| Kashman, Y; Lang, S; Pappo, D; Vartanian, M | 1 |
| Hirai, Y; Hisayasu, S; Shimada, T; Takakusaki, Y | 1 |
| Dierks, T; Gasow, K; Preusser-Kunze, A; Roeser, D; Rudolph, MG; Schmidt, B; von Figura, K; Wittmann, JG | 1 |
| Bertozzi, CR; Rush, J | 1 |
| Bertozzi, CR; Carlson, BL; Carrico, IS | 1 |
| Preusser-Kunze, A; Roeser, D; Rudolph, MG; Schmidt, B | 1 |
| Benjdia, A; Berteau, O; Leprince, J; Sandström, C; Vaudry, H | 1 |
| Bond, T; Goslan, EH; Henriet, O; Jefferson, B; Parsons, SA | 1 |
| Benjdia, A; Berteau, O; Johnson, MK; Leprince, J; Subramanian, S; Vaudry, H | 1 |
| Bertozzi, CR; deHart, GW; Rabuka, D; Rush, JS; Wu, P | 1 |
| Chang, MS; Chung, YK; Jin, DK; Kim, CH; Ko, AR; Kwun, Y; Lee, J; Lee, JY; Sohn, JM; Sohn, YB; Yook, YJ | 1 |
| Appel, MJ; Bertozzi, CR | 1 |
| Alam, S; Dierks, T; Mariappan, M; May, C; Peng, J; Radhakrishnan, K; Rudolph, MG; Schmidt, B; von Figura, K | 1 |
| Breetveld, R; Fascione, M; Signoret, N; Spicer, CD; Warnes, ME; Yates, NDJ | 1 |
2 review(s) available for alanine and c(alpha)-formylglycine
| Article | Year |
|---|---|
A major step on the road to understanding a unique posttranslational modification and its role in a genetic disease.
Topics: Alanine; Animals; Catalytic Domain; Gene Expression Regulation, Enzymologic; Glycine; Humans; Mutation; Protein Processing, Post-Translational; Sphingolipidoses; Sulfatases | 2003 |
Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
Topics: Alanine; Animals; Binding Sites; Biotechnology; Catalysis; Catalytic Domain; Cysteine; Glycine; Humans; Models, Molecular; Protein Processing, Post-Translational; Serine; Sulfotransferases | 2015 |
31 other study(ies) available for alanine and c(alpha)-formylglycine
| Article | Year |
|---|---|
Conversion of cysteine to formylglycine: a protein modification in the endoplasmic reticulum.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Biological Transport; Cerebroside-Sulfatase; Cysteine; Endoplasmic Reticulum; Glycine; Humans; Lysosomal Storage Diseases; Molecular Sequence Data; Protein Biosynthesis; Protein Processing, Post-Translational | 1997 |
Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine.
Topics: Alanine; Amino Acid Sequence; Arylsulfatases; Glycine; Klebsiella pneumoniae; Molecular Sequence Data; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Serine | 1998 |
Sulfatases, trapping of the sulfated enzyme intermediate by substituting the active site formylglycine.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Catechols; Cerebroside-Sulfatase; Chondro-4-Sulfatase; Galactose; Glycine; Humans; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Serine; Sulfuric Acid Esters | 1998 |
Conversion of cysteine to formylglycine in eukaryotic sulfatases occurs by a common mechanism in the endoplasmic reticulum.
Topics: Alanine; Animals; Cell Line; Cerebroside-Sulfatase; Chondro-4-Sulfatase; Cricetinae; Cysteine; Endoplasmic Reticulum; Eukaryotic Cells; Glycine; Humans; Protein Processing, Post-Translational; Time Factors | 1998 |
Posttranslational formation of formylglycine in prokaryotic sulfatases by modification of either cysteine or serine.
Topics: Alanine; Arylsulfatases; Bacterial Proteins; Binding Sites; Borohydrides; Cysteine; Glycine; Klebsiella pneumoniae; Mutagenesis, Site-Directed; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Recombinant Proteins; Sequence Analysis; Serine; Sulfates; Trypsin | 1998 |
Residues critical for formylglycine formation and/or catalytic activity of arylsulfatase A.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Catalysis; Cell Line; Cerebroside-Sulfatase; Cricetinae; Gene Expression; Genetic Vectors; Glycine; Humans; Kidney; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed | 1998 |
Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalytic Domain; Cerebroside-Sulfatase; Cysteine; DNA Primers; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid | 1999 |
The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase.
Topics: Alanine; Bacterial Proteins; Borohydrides; Cloning, Molecular; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Molecular Sequence Data; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfatases; Transfection | 1999 |
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates.
Topics: Alanine; Antineoplastic Agents; Arylsulfatases; Binding Sites; Breast Neoplasms; Coumarins; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estrone; Female; Glycine; Heterocyclic Compounds, 3-Ring; Humans; Hydrogen Bonding; Kinetics; Microsomes; Models, Molecular; Placenta; Postmenopause; Steryl-Sulfatase; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids | 2000 |
Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
Topics: Alanine; Binding Sites; Catalysis; Catechols; Cations, Divalent; Cerebroside-Sulfatase; Crystallography, X-Ray; Glycine; Humans; Hydrogen Bonding; Models, Molecular; Mutation; Protein Conformation | 2001 |
Characterization of posttranslational formylglycine formation by luminal components of the endoplasmic reticulum.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Calcium; Catalysis; Cattle; Detergents; Dogs; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Glycine; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Microsomes; Microsomes, Liver; Molecular Sequence Data; Pancreas; Peptides; Protein Biosynthesis; Protein O-Methyltransferase; Protein Processing, Post-Translational; Protein Transport; Ribosomes; Salts; Temperature; Time Factors | 2001 |
Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Arylsulfatases; beta-Galactosidase; Blotting, Western; Cysteine; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Processing, Post-Translational; Protein Sorting Signals; Serine; Subcellular Fractions; Sulfatases; Two-Hybrid System Techniques | 2003 |
The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. A structural and biochemical study of the enzyme active site and saccharide substrate specificity.
Topics: Alanine; Binding Sites; Disaccharides; Flavobacterium; Glycine; Heparin; Heparitin Sulfate; Metals; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Sulfatases | 2003 |
Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Alanine; Amino Acid Sequence; Glycine; Klebsiella; Molecular Sequence Data; Pseudomonas; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfatases; Trypsin | 2003 |
Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Biological Assay; Cattle; CHO Cells; Chromosomes, Human, Pair 3; Cricetinae; DNA, Complementary; Endoplasmic Reticulum; Enzymes; Gene Expression Regulation, Enzymologic; Genetic Vectors; Glycine; Humans; Mice; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Sphingolipidoses; Sulfatases; Transduction, Genetic | 2003 |
The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Conserved Sequence; Eukaryotic Cells; Glycine; Humans; Molecular Sequence Data; Multigene Family; Oxidoreductases Acting on Sulfur Group Donors; Phylogeny; Prokaryotic Cells; Protein Processing, Post-Translational; Sequence Alignment; Sequence Homology, Amino Acid; Sulfatases | 2003 |
Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.
Topics: Alanine; Binding Sites; Binding, Competitive; Blotting, Northern; Blotting, Western; Catalysis; Cell Line; Codon; Cross-Linking Reagents; DNA, Complementary; Endoplasmic Reticulum; Fibroblasts; Fluorescent Antibody Technique, Indirect; Glycine; Glycosylation; Humans; Immunoprecipitation; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mass Spectrometry; Microscopy, Immunoelectron; Molecular Sequence Data; Oxidoreductases Acting on Sulfur Group Donors; Peptides; Protein Processing, Post-Translational; Recombinant Proteins; Skin; Sulfatases; Time Factors; Tissue Distribution; Transfection; Trypsin; Two-Hybrid System Techniques | 2005 |
Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Calcium; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glycine; Humans; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation, Missense; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Oxygen; Protein Structure, Secondary; Sequence Homology, Amino Acid; Sphingolipidoses; Sulfatases; Tumor Cells, Cultured | 2005 |
Synthesis of cyclic endiamino peptides.
Topics: Alanine; Amino Acids, Diamino; Glycine; Peptides, Cyclic; Pyrazines | 2005 |
Coexpression of formylglycine-generating enzyme is essential for synthesis and secretion of functional arylsulfatase A in a mouse model of metachromatic leukodystrophy.
Topics: Alanine; Animals; Blood-Brain Barrier; Cerebroside-Sulfatase; Chlorocebus aethiops; COS Cells; Gene Transfer Techniques; Genetic Therapy; Glycine; Injections, Intravenous; Leukodystrophy, Metachromatic; Mice; Mice, Knockout; Oxidoreductases Acting on Sulfur Group Donors; Plasmids; Sulfatases; Transduction, Genetic; Transfection | 2005 |
A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme.
Topics: Alanine; Amino Acid Sequence; Cell Line, Tumor; Crystallization; Enzyme Activation; Glycine; Humans; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on Sulfur Group Donors; Protein Binding; Protein Conformation; Substrate Specificity; Sulfatases | 2006 |
An alpha-formylglycine building block for fmoc-based solid-phase peptide synthesis.
Topics: Alanine; Binding Sites; Glycine; Mycobacterium tuberculosis; Peptides; Sulfatases | 2006 |
Introducing genetically encoded aldehydes into proteins.
Topics: Alanine; Aldehydes; Amino Acid Sequence; Animals; Consensus Sequence; Conserved Sequence; Glycine; Humans; Molecular Sequence Data; Peptide Fragments; Protein Processing, Post-Translational; Proteins; Sequence Tagged Sites; Sulfatases | 2007 |
Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.
Topics: Alanine; Binding Sites; Crystallization; Enzymes; Glycine; Halogens; Humans; Models, Molecular; Molecular Probes; Oxygen | 2007 |
Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme.
Topics: Alanine; Anaerobiosis; Catalysis; Clostridium perfringens; Deoxyadenosines; Glycine; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfatases | 2009 |
Disinfection byproduct formation and fractionation behavior of natural organic matter surrogates.
Topics: Acetone; Alanine; Bromides; Chloral Hydrate; Chlorine; Disinfection; Glycine; Halogens; Kinetics; Organic Chemicals; Oxidation-Reduction; Water; Water Pollutants, Chemical; Water Purification | 2009 |
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?
Topics: Alanine; Anaerobiosis; Binding Sites; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Eukaryota; Glycine; Iron-Sulfur Proteins; Oxidation-Reduction; S-Adenosylmethionine; Serine; Substrate Specificity; Sulfatases | 2010 |
Site-specific chemical protein conjugation using genetically encoded aldehyde tags.
Topics: Alanine; Aldehydes; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Escherichia coli; Glycine; Mass Spectrometry; Oxidoreductases Acting on Sulfur Group Donors; Proteins; Recombinant Proteins; Sulfatases | 2012 |
A biochemical and physicochemical comparison of two recombinant enzymes used for enzyme replacement therapies of hunter syndrome.
Topics: Alanine; Animals; CHO Cells; Cricetinae; Cricetulus; Enzyme Replacement Therapy; Fibroblasts; Glycine; Humans; Iduronate Sulfatase; Mannosephosphates; Mucopolysaccharidosis II; N-Acetylneuraminic Acid; Recombinant Fusion Proteins | 2014 |
Eukaryotic formylglycine-generating enzyme catalyses a monooxygenase type of reaction.
Topics: Alanine; Animals; Baculoviridae; Biocatalysis; Catalytic Domain; Cysteine; Disulfides; Dithiothreitol; Enzyme Assays; Gene Expression; Glycine; Humans; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Oxygen; Recombinant Proteins; Sf9 Cells; Spodoptera; Sulfatases | 2015 |
Preparation and Application of an Inexpensive α-Formylglycine Building Block Compatible with Fmoc Solid-Phase Peptide Synthesis.
Topics: Alanine; Glycine; Peptides; Solid-Phase Synthesis Techniques; Sulfatases | 2023 |