alanine has been researched along with beta-(5-hydroxy-2-pyridyl)alanine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 15 (51.72) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita-Yoshigaki, J; Nishimura, S; Shindo-Okada, N; Yokoyama, S | 1 |
| Kameyama, T; Matano, S; Nakamura, S; Nomura, T; Okada, G; Ryoyama, K | 1 |
| Baskin, L; Brandt-Rauf, PW; Chung, DL; Dykes, DC; Friedman, F; Joran, A; Murphy, RB; Robinson, R; Ronai, Z; Weinstein, IB | 1 |
| Doi, S; Izawa, M; Katsuki, M; Kimura, M; Nishimura, S; Shindo-Okada, N; Takayama, S | 1 |
| Brandt-Rauf, PW; Chung, DL; Murphy, RB; Nishimura, S; Pincus, MR; Weinstein, IB; Yamaizumi, Z | 1 |
| Krzyzosiak, WJ; Nakajima, K; Nishimura, S; Shindo-Okada, N; Teshima, H | 1 |
| Kyprianou, N; Taylor-Papadimitriou, J | 1 |
| Brandt-Rauf, P; Chung, DL; Murphy, RB; Nishimura, S; Pincus, MR; Weinstein, IB; Yamaizumi, Z | 1 |
| Nishimura, S; Okada, N | 1 |
| Makabe, O; Nagahara, H; Nishimura, S; Shindo-Okada, N | 2 |
| Makabe, O; Nagahara, H; Nishimura, S; Shindo-Okada, N; Yamaizumi, Z | 1 |
| Benoit, RM; Eiseman, J; Jacobs, SC; Kyprianou, N | 1 |
| Castle, D; Dent, P; Romero, G; Sturgill, TW; Vincent, LA; Wu, J | 1 |
| Dupressoir, T; Koering, CE; Rommelaere, J; Schlehofer, JR; Stehelin, D; Vennin-Fikry, M | 1 |
| Monden, Y; Nishimura, S; Shindo-Okada, N | 1 |
| Hamano Takaku, F; Monden, Y; Nishimura, S; Shindo Okada, N | 1 |
| Lecointe, L; Martinez, J; Pappalardo, L; Rolland, V; Roumestant, ML; Viallefont, P | 1 |
| Hamano-Takaku, F; Iwama, T; Kitabatake, M; Monden, Y; Nishimura, S; Saito-Yano, S; Soll, D; Takaku, K | 1 |
| Burke, TR; Miyoshi, K; Otaka, A; Wu, L; Yao, ZJ; Ye, B; Zhang, ZY | 1 |
| Phillips, RS; Watkins, EB | 2 |
| Adamczyk, M; Akireddy, SR; Reddy, RE | 1 |
| Arce, CA; Barra, HS; Bisig, CG; Contin, MA; Purro, SA | 1 |
| Hwang, TL; Lee, O; Lee, SJ; Shu, CY; Tseng, YJ; Wang, HP | 1 |
| Martinez, J; Meffre, P; Moussa, A; Rolland, V | 1 |
| Chang, FS; Huang, CF; Lee, O; Li, EI; Lian, JF; Liou, JP; Pan, SL; Teng, CM; Wang, CL; Wang, HP | 1 |
| Cheng, YW; Huang, SH; Huang, WK; Hung, CH; Kang, JJ; Liao, PL; Tsai, CH; Wang, HP | 1 |
| Ahmad, R; Azizan, KA; Baharum, SN; Goh, KJ; Goh, YK; Ong, CE | 1 |
2 review(s) available for alanine and beta-(5-hydroxy-2-pyridyl)alanine
| Article | Year |
|---|---|
[Mechanism of action of azatyrosine: recent process].
Topics: 3T3 Cells; Alanine; Animals; Antibiotics, Antineoplastic; Cell Division; Genes, ras; Humans; Mice; Proteins; Receptor, ErbB-2; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Azatyrosine. Mechanism of action for conversion of transformed phenotype to normal.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Genes, erbB-2; Humans; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Signal Transduction; Tyrosine-tRNA Ligase | 1999 |
27 other study(ies) available for alanine and beta-(5-hydroxy-2-pyridyl)alanine
| Article | Year |
|---|---|
Azatyrosine inhibits neurite outgrowth of PC12 cells induced by oncogenic Ras.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Bucladesine; Cell Differentiation; Genes, ras; Microinjections; Nerve Growth Factors; Neurites; Oncogene Protein p21(ras); PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf | 1992 |
Non-transformed, but not ras/myc-transformed, serum-free mouse embryo cells recover from growth suppression by azatyrosine.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Blotting, Northern; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Embryo, Mammalian; Exons; Gene Expression; Genes, myc; Genes, ras; HeLa Cells; Humans; Kinetics; Mice; Mice, Inbred BALB C; RNA; Time Factors | 1992 |
Evidence that oocyte maturation induced by an oncogenic ras-p21 protein and insulin is mediated by overlapping yet distinct mechanisms.
Topics: Alanine; Alkaloids; Amino Acid Sequence; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Female; Insulin; Molecular Sequence Data; Oligopeptides; Oncogene Protein p21(ras); Oocytes; Protein Kinase C; Protein Prenylation; Signal Transduction; Staurosporine; Xenopus laevis | 1992 |
Inhibition of chemical carcinogenesis in vivo by azatyrosine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alanine; Animals; Antibiotics, Antineoplastic; Drug Screening Assays, Antitumor; Genes, ras; Methylnitrosourea; Mice; Mutation; Papilloma; Skin Neoplasms; Stomach Neoplasms | 1992 |
Evidence that the ras oncogene-encoded p21 protein induces oocyte maturation via activation of protein kinase C.
Topics: Alanine; Alkaloids; Animals; Enzyme Activation; Humans; Oncogenes; Oogenesis; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Staurosporine; Xenopus laevis | 1992 |
Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine.
Topics: 3T3 Cells; Alanine; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; Collagen; Fibronectins; Gene Expression; Genes, Intracisternal A-Particle; Genes, Tumor Suppressor; GTP-Binding Proteins; Membrane Proteins; Mice; Molecular Sequence Data; Phenotype; rhoB GTP-Binding Protein; RNA, Messenger | 1992 |
Isolation of azatyrosine-induced revertants from ras-transformed human mammary epithelial cells.
Topics: Alanine; Animals; Blotting, Northern; Breast; Cell Division; Cell Transformation, Viral; Cells, Cultured; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Mice; Mice, Nude; Oncogene Protein p21(ras); RNA, Messenger | 1992 |
A peptide from the GAP-binding domain of the ras-p21 protein as well as azatyrosine block ras-induced maturation of Xenopus oocytes.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Differentiation; Cloning, Molecular; Female; Genes, ras; Genes, Synthetic; GTPase-Activating Proteins; Humans; Insulin; Kinetics; Molecular Sequence Data; Oocytes; Peptides; Proteins; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; Time Factors; Xenopus laevis | 1991 |
[Characteristics of revertant cells induced from transformed cells by the treatment with an antibiotic, azatyrosine].
Topics: Alanine; Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans | 1990 |
Permanent conversion of NIH3T3 cells transformed by activated c-Ha-ras, c-Ki-ras, N-ras, or c-raf, and of human pancreatic adenocarcinoma containing activated c-Ki-ras to apparently normal cells by treatment with the antibiotic azatyrosine.
Topics: Adenocarcinoma; Alanine; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Oncogenes; Pancreatic Neoplasms; Tumor Cells, Cultured | 1990 |
Permanent conversion of mouse and human cells transformed by activated ras or raf genes to apparently normal cells by treatment with the antibiotic azatyrosine.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Blotting, Southern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Mice; Oncogene Protein p21(ras); Proto-Oncogenes | 1989 |
The antibiotic, L-beta-(5-hydroxy-2-pyridyl)-alanine specifically inhibits growth of the NIH3T3 cells transformed by activated human c-Ha-ras and induces formation of flat revertant cells.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; Humans; Mice | 1988 |
Reversion of human prostate tumorigenic growth by azatyrosine.
Topics: Adenocarcinoma; Alanine; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, SCID; Oncogenes; Point Mutation; Prostatic Neoplasms; Protein-Lysine 6-Oxidase; Proto-Oncogene Mas; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Up-Regulation | 1995 |
Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells.
Topics: 3T3 Cells; Alanine; Animals; Cell Line, Transformed; Cell Membrane; Cell-Free System; Enzyme Activation; Guanosine Triphosphate; Insulin; Mice; Microscopy, Electron; Mitogen-Activated Protein Kinase 1; Octoxynol; Platelet-Derived Growth Factor; Polyethylene Glycols; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Signal Transduction | 1993 |
Sensitivity to the parvovirus minute virus of mice as a probe for azatyrosine-mediated phenotypic reversion of spontaneously transformed cells.
Topics: 3T3 Cells; Alanine; Animals; Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Minute Virus of Mice; Phenotype | 1996 |
Diastereoselective synthesis of non-proteinogenic alpha-amino acids.
Topics: Alanine; Chromatography; Chromatography, High Pressure Liquid; Mass Spectrometry; Phenylalanine; Stereoisomerism | 2000 |
A mutant Escherichia coli tyrosyl-tRNA synthetase utilizes the unnatural amino acid azatyrosine more efficiently than tyrosine.
Topics: Alanine; Base Sequence; DNA Primers; Escherichia coli; Genes, Bacterial; Models, Molecular; Mutagenesis; Plasmids; Protein Conformation; Tyrosine; Tyrosine-tRNA Ligase | 2000 |
Phospho-Azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosine.
Topics: Alanine; Animals; Anticarcinogenic Agents; Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Kinetics; Molecular Mimicry; Peptides; Phosphotyrosine; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Substrate Specificity | 2001 |
Enzymatic synthesis of aza-l-tyrosines.
Topics: Alanine; Antibiotics, Antineoplastic; Citrobacter freundii; Pyridines; Pyridones; Tyrosine Phenol-Lyase | 2001 |
Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine.
Topics: Alanine; Antibiotics, Antineoplastic; Catalysis; Hydrogen; Pyridines; Stereoisomerism | 2001 |
Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine.
Topics: Alanine; Citrobacter freundii; Enzyme Inhibitors; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Tyrosine Phenol-Lyase | 2001 |
Post-translational incorporation of the antiproliferative agent azatyrosine into the C-terminus of alpha-tubulin.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Brain Chemistry; Carboxypeptidases; Cell Division; Cell Extracts; Cell Line; Microtubules; Neoplasms, Experimental; Protein Processing, Post-Translational; Rats; Rats, Wistar; Tubulin; Tumor Cells, Cultured | 2003 |
Selective cytotoxicity of azatyrosinamides against ras-transformed NIH 3T3 cells.
Topics: Alanine; Amides; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Transformed; Inhibitory Concentration 50; Mice; NIH 3T3 Cells; ras Proteins; Structure-Activity Relationship | 2005 |
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives.
Topics: Alanine; Chymotrypsin; Enzyme Inhibitors; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2012 |
Azatyrosinamides: novel RAS-related anticancer agents.
Topics: Alanine; Animals; Antineoplastic Agents; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasms, Experimental; NIH 3T3 Cells; Xenograft Model Antitumor Assays | 2013 |
Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Disease Models, Animal; Gene Expression Regulation; Histone Deacetylase Inhibitors; Hydroxamic Acids; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Mucositis; Rats | 2019 |
Growth modulation and metabolic responses of Ganoderma boninense to salicylic acid stress.
Topics: Alanine; Arecaceae; Carbohydrates; Carbon; Chromatography, Liquid; Cluster Analysis; Coumarins; Culture Media; Ganoderma; In Vitro Techniques; Ions; Lipids; Mass Spectrometry; Melanins; Phenols; Phenylalanine; Plant Diseases; Plant Roots; Salicylic Acid; Tryptophan | 2021 |