alanine has been researched along with alpha-chymotrypsin in 109 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 80 (73.39) | 18.7374 |
| 1990's | 17 (15.60) | 18.2507 |
| 2000's | 9 (8.26) | 29.6817 |
| 2010's | 3 (2.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kupfer, S; Tschesche, H | 1 |
| Takahashi, K | 1 |
| Engel, J; Kupfer, S; Quast, U; Steffen, E; Tschesche, H | 1 |
| Adams, JG; Honig, GR; Mason, RG; Romain, PL; Schwartz, AD; Shamsuddin, M; Vida, LN | 1 |
| Grieco, C; Hansch, C; Silipo, C; Smith, RN; Vittoria, A; Yamada, K | 1 |
| Feinstein, G; Levy, H | 1 |
| Hopkins, TR; Sharma, SK | 3 |
| Manavalan, P; Ponnuswamy, PK; Srinivasan, AR | 1 |
| Ikenaka, T; Odani, S | 1 |
| Engel, J; Jering, H; Mair, G; Quast, U; Steffen, E; Tschesche, H | 1 |
| Engel, J; Jering, H; Kupfer, S; Quast, U; Steffen, E; Tschesche, H | 1 |
| FitzGerald, D; Kasturi, S; Kihara, A; Pastan, I | 1 |
| Haskell, JH; Silver, MS | 1 |
| Beckmann, J; Mehlich, A; Tschesche, H; Wenzel, HR | 1 |
| Goto, M; Nohara, D; Sakai, T; Wakamatsu, M | 1 |
| Makimoto, S; Taniguchi, Y | 1 |
| Katzenellenbogen, JA; Kinder, DH | 1 |
| Bonicel, J; Bousset-Risso, M; Rovery, M | 1 |
| Callahan, HJ; Liberti, PA; Maurer, PH | 1 |
| Maurer, PH; Odstrchel, G | 1 |
| Blondin, J; Janoff, A | 1 |
| Carrara, MC; Park, WK; Regoli, D | 1 |
| Ikenaka, T; Murao, S; Nabeshima, Y; Odani, S; Sakai, M; Sato, S | 1 |
| Biserte, G; Dautrevaux, M; Han, KK; Mizon, J | 1 |
| Konovessi-Panayotatos, A; Schultz, RM; Treadway, WJ | 1 |
| Escher, E; Schwyzer, R | 1 |
| Ichikawa, T; Kondo, M; Watabe, K | 1 |
| McClune, G; Uretsky, LS; Wedler, FC | 1 |
| Spencer, EM | 1 |
| Hermodson, M; Hornung, S; Kurachi, S; Stamatoyannopoulos, G | 1 |
| Markussen, J; Sundby, F | 1 |
| Das, BC; Gros, C; Lederer, E; Petit, JF; Wietzerbin-Falszpan, J | 1 |
| Rees, MW; Short, MN | 1 |
| Steiner, DF; Tager, HS | 1 |
| Lipkind, GM; Popov, EM | 1 |
| Blow, DM; Huber, R; Kukla, D; Rühlmann, A; Steigemann, W; Wright, CS | 1 |
| Kaplan, H | 1 |
| Fastrez, J; Fersht, AR | 1 |
| Bender, ML; Valenzuela, P | 2 |
| Harrap, BS; Heidemann, ER; Schiele, HD | 1 |
| Tulinsky, A; Vandlen, RL | 1 |
| Szabó, T; Vajda, T | 2 |
| Ako, H; Foster, RJ; Ryan, CA | 1 |
| Biserte, G; Laine, B; Mizon, J; Ruffin, P; Sautière, P; Tyrou, D | 1 |
| Fric, P; Kasafírek, E; Malis, F | 1 |
| Bump, S; Deyl, Z; Rosmus, J | 1 |
| Ramachandran, GN; Venkatachalam, CM | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Margoliash, E; Nolan, C; Peterson, JD; Steiner, DF | 1 |
| Crumm, S; Saffran, M; Wuu, TC | 1 |
| Kitchen, H; Kouba, EO | 1 |
| Madison, V; Schellman, J | 1 |
| Matta, MS; Silver, MS | 1 |
| DeLange, RJ; Huang, TS | 1 |
| Geokas, MC; Rinderknecht, H; Silverman, P | 1 |
| Gabel, D; Katchalski, E; Steinberg, IZ | 1 |
| Friedberg, F; Riesz, P | 1 |
| Gertler, A; Hofmann, T | 1 |
| DeVries, AL; Feeney, RE; Komatsu, S | 1 |
| Caillet, J; Maigret, M; Pullman, B | 1 |
| Canfield, RE; Morgan, FJ | 1 |
| Botes, DP; Strydom, AJ | 1 |
| Maigret, B; Perahia, D; Pullman, B | 1 |
| Miyatake, A; Wada, H; Watanabe, T | 1 |
| Hsu, CJ; Kelleher, G; Wagner, T | 1 |
| Prothero, JW | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Indada, Y; Matsushima, A; Nomoto, M; Sakurai, K; Shibata, K | 1 |
| Ptitsyn, OB | 1 |
| Hein, GE; Ponzi, DR | 1 |
| Carrell, RW; Gajdusek, DC; Guiart, J; Irvine, D; Kirk, RL; Kynoch, PA; Lehmann, H | 1 |
| Andersson, L; Wolfenden, R | 1 |
| Chen, Y; White, EH | 1 |
| Agard, DA; Mace, JE; Wilk, BJ | 1 |
| Li, M; Luo, W; White, EH | 1 |
| Li, M; Roswell, DF; White, EH | 1 |
| Elmasry, N; Fersht, AR; Harpaz, Y; Henrick, K | 1 |
| Naito, A; Saitô, H; Tuzi, S | 1 |
| Anderson, S; Castro, MJ | 1 |
| Fersht, AR; Itzhaki, LS; Ladurner, AG | 1 |
| Beighton, D; de Graaff, J; Homer, KA | 1 |
| Takeda-Shitaka, M; Umeyama, H | 1 |
| Frank, EG; Gonzalez, M; Levine, AS; Woodgate, R | 1 |
| Gráf, L; Hudáky, P; Kaslik, G; Venekei, I | 1 |
| Kirley, TL; Lewis Carl, SA; Smith, TM | 1 |
| Anderson, S; Bateman, KS; Ding, J; Ganz, PJ; James, MN; Laskowski, M; Lu, SM; Markley, JL; Qasim, MA; Saunders, CW; Song, J | 1 |
| Iwanaga, S; Kimura, M; Kouzuma, Y; Miyamoto, A; Nagata, R; Yamasaki, N | 1 |
| Ambler, J; Baettig, U; Brown, L; Brundish, D; Cockcroft, X; Dell, C; Furzer, A; Garman, S; Janus, D; Kane, PD; Mitchelson, A; Smith, G; Talbot, MD; Tweed, M; Walker, CV; Wills, N | 1 |
| Allen, M; Ambler, J; Butler, K; Cockcroft, X; Dunnet, K; Hayler, J; Kane, PD; LeGrand, D; Lugrin, F; Menear, K; Mitchelson, A; Price, R; Talbot, M; Tweed, M; Wills, N | 1 |
| Belozersky, MA; Dunaevsky, YE; Egorov, TA; Musolyamov, AK | 1 |
| Daggett, V; Pan, Y | 1 |
| Kim, KH | 1 |
| Buczek, O; Dadlez, M; Koscielska-Kasprzak, K; Krowarsch, D; Otlewski, J | 1 |
| DESNUELLE, P; ROVERY, M | 1 |
| GERATZ, JD | 1 |
| KOSHLAND, DE; STRUMEYER, DH; WHITE, WN | 1 |
| GORDY, W; PATTEN, RA | 1 |
| GUEST, JR; YANOFSKY, C | 1 |
| FLEISHER, GA; ISHIMARU, T; RAMACHANDER, G; ZELLER, EA; ZELLER, V | 1 |
| Antal, J; Gráf, L; Jelinek, B; Venekei, I | 1 |
| Bordusa, F; Elsner, C; Günther, R; Hofmann, HJ; Schmidt, S | 1 |
| McCrudden, MT; Ryan, LA; Timson, DJ; Turkington, P | 1 |
| Martinez, J; Meffre, P; Moussa, A; Rolland, V | 1 |
| Huscroft, M; Kazlauciunas, A; Khuphe, M; Thornton, PD | 1 |
| Carpentier, SC; Delcour, JA; Lambrecht, MA; Rombouts, I | 1 |
2 review(s) available for alanine and alpha-chymotrypsin
| Article | Year |
|---|---|
Conformation of polypeptide chains.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carboxypeptidases; Chemical Phenomena; Chemistry; Chymotrypsin; Collagen; Dipeptides; Esters; Fibroins; Glutamates; Glycine; Hemoglobins; Heterocyclic Compounds; Muramidase; Myoglobin; Oxytocin; Papain; Peptides; Proline; Ribonucleases; Statistics as Topic; Stereoisomerism; Sulfides; Tyrosine; Tyrothricin; Valine; Vasopressins; X-Ray Diffraction | 1969 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
107 other study(ies) available for alanine and alpha-chymotrypsin
| Article | Year |
|---|---|
Hydrolysis-resynthesis equilibrium of the lysine-15--alanine-16 peptide bond in bovine trypsin inhibitor (Kunitz).
Topics: Alanine; Binding Sites; Carboxypeptidases; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Fibrinolysin; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Oxidation-Reduction; Trypsin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors | 1976 |
The structure and function of ribonuclease T1. XXI. Modification of histidine residues in ribonuclease T1 with iodoacetamide.
Topics: Alanine; Amino Acids; Binding Sites; Chymotrypsin; Guanine Nucleotides; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Methylation; Peptides; Ribonuclease T1; Ribonucleases | 1976 |
Kinetics of the interaction of alpha-chymotrypsin with trypsin kallikrein inhibitor (Kunitz) in which the reactive-site peptide bond Lys-15--Ala-16 is split.
Topics: Alanine; Aprotinin; Binding Sites; Chymotrypsin; Hydrogen-Ion Concentration; Kinetics; Lysine; Trypsin | 1978 |
Hemoglobin J-Chicago (beta76(E20) Ala yields Asp): a new hemoglobin variant resulting from substitution of an external residue.
Topics: 1-Propanol; Alanine; Amino Acids; Amino Alcohols; Ampicillin; Anemia, Hypochromic; Aspartic Acid; Autoanalysis; Blood Protein Electrophoresis; Chicago; Child, Preschool; Chymotrypsin; Diphosphoglyceric Acids; Globins; Glucosephosphate Dehydrogenase; Hemoglobins, Abnormal; Humans; Inclusion Bodies; Iron; Male; Oxygen Consumption; Peptides; Protein Denaturation; Spectrophotometry; Trypsin | 1975 |
Quantitative structure-activity relationships of chymotrypsin-ligand interactions: An analysis of interactions in p3 space.
Topics: Alanine; Chymotrypsin; Kinetics; Ligands; Models, Biological; Structure-Activity Relationship | 1979 |
The digestion of the oxidized B chain of insulin by human neutrophile proteases: elastase and chymotrypsin-like protease.
Topics: Alanine; Animals; Chymotrypsin; Humans; Insulin; Leucine; Neutrophils; Pancreatic Elastase; Peptide Hydrolases; Phenylalanine; Species Specificity; Substrate Specificity; Swine; Valine | 1979 |
On the activation of bovine chymotrypsinogen A. Preparation of alanine-neochymotrypsinogen and its activation to alpha-chymotrypsin.
Topics: Alanine; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Chymotrypsinogen; Drug Stability; Enzyme Activation; Kinetics; Pancreas; Protein Denaturation; Structure-Activity Relationship; Trypsin Inhibitors | 1978 |
Solvent accessibilities in glycyl, alanyl and seryl dipeptides.
Topics: Alanine; Chymotrypsin; Dipeptides; Glycine; Hydrogen Bonding; Models, Chemical; Muramidase; Protein Conformation; Serine; Solvents | 1977 |
Studies on soybean trypsin inhibitors. IV. Change of the inhibitory activity of Bowman-Birk inhibitor upon replacements of the alpha-chymotrypsin reactive site serine residue by other amino acids.
Topics: Alanine; Binding Sites; Chymotrypsin; Glycine; Leucine; Serine; Structure-Activity Relationship; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors; Valine | 1978 |
Kinetics of binding of bovine trypsin-killikrein inhibitor (K unitz) in which the reactive-site peptide bond Lys-15--Ala-16 is cleaved, to alpha-chymotrypsin and beta-trypsin.
Topics: Alanine; Animals; Binding Sites; Cattle; Chymotrypsin; Kinetics; Lysine; Protein Binding; Trypsin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors | 1975 |
The effect of cleaving the reactive-site peptide bond Lys-15--Ala-16 on the conformation of bovine trypsin-kallikrein inhibitor (K unitz) as revealed by solvent-perturbation spectra, circular dichroism and fluorescence.
Topics: Alanine; Animals; Binding Sites; Cattle; Chymotrypsin; Circular Dichroism; Lysine; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trypsin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors | 1975 |
Alanine scanning mutagenesis identifies surface amino acids on domain II of Pseudomonas exotoxin required for cytotoxicity, proper folding, and secretion into periplasm.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Alanine; Animals; Bacterial Toxins; Cell Line; Cell Survival; Chymotrypsin; Escherichia coli; Exotoxins; Humans; Mice; Mutagenesis, Site-Directed; Protein Folding; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Structure-Activity Relationship; Trypsin; Tumor Cells, Cultured; Virulence Factors | 1992 |
Chemistry in a microenvironment of low pH, generated with the aid of an immobilized proteinase.
Topics: Alanine; Buffers; Chemical Phenomena; Chemistry; Chymotrypsin; Collodion; Diffusion; Enzymes, Immobilized; Hydrazines; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Phenylalanine; Prodrugs; Solutions; Tyrosine | 1990 |
Aprotinin derivatives with chromophoric leaving groups can be used as highly selective active-site titrants for serine proteinases and permit the determination of kinetic constants of enzyme-inhibitor complexes.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Aprotinin; Binding Sites; Chromatography, High Pressure Liquid; Chymotrypsin; Coumarins; Fluorometry; Humans; Indicators and Reagents; Kallikreins; Kinetics; Leukocytes; Lysine; Molecular Sequence Data; Pancreatic Elastase; Serine Endopeptidases; Spectrophotometry; Trypsin | 1988 |
Kinetic anomalies in chymotryptic hydrolyses of p-nitrophenyl acetate and N-benzoyl-L-alanine methyl ester.
Topics: Alanine; Chymotrypsin; Hydrolysis; Nitrophenols; Thermodynamics | 1989 |
Effect of pressure on the pre-steady-state kinetics of the hydrolysis of anilide substrates catalyzed by alpha-chymotrypsin.
Topics: Alanine; Chymotrypsin; Dipeptides; Hydrolysis; Kinetics; Pressure; Protein Binding; Substrate Specificity | 1987 |
Acylamino boronic acids and difluoroborane analogues of amino acids: potent inhibitors of chymotrypsin and elastase.
Topics: Acylation; Alanine; Amino Acids; Binding, Competitive; Boranes; Boronic Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Glycine; Hydrolysis; Isoleucine; Pancreatic Elastase; Phenylalanine; Structure-Activity Relationship; Valine | 1985 |
Limited proteolysis of porcine pancreatic lipase. Lability of the Phe 335-Ala 336 bond towards chymotrypsin.
Topics: Alanine; Animals; Chromatography, Gel; Chymotrypsin; Electrophoresis, Polyacrylamide Gel; Lipase; Pancreas; Peptide Fragments; Phenylalanine; Substrate Specificity; Swine | 1985 |
Immunochemical characterization of the antigenic determinant of a synthetic polypeptide.
Topics: Alanine; Animals; Antigen-Antibody Reactions; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cross Reactions; Epitopes; Glutamates; Guinea Pigs; Immune Sera; Lysine; Mathematics; Molecular Weight; Papain; Pepsin A; Peptides; Precipitin Tests; Pronase; Protein Conformation; Rabbits; Sheep; Stereoisomerism; Ultracentrifugation; Viscosity | 1971 |
Antigenicity of polypeptides (poly amino acids): nature of the immunochemical determinants in the neutral copolymer poly ( -N-hydroxypropyl glutamide 60 alanine 30 tyrosine 10 ) (GAT amide).
Topics: Alanine; Amides; Amines; Amino Acids; Animals; Antibody Specificity; Cattle; Chymotrypsin; Cross Reactions; Epitopes; Glutamine; Immunodiffusion; Passive Cutaneous Anaphylaxis; Peptides; Precipitin Tests; Pronase; Rabbits; Sheep; Tyrosine | 1972 |
The effect of human granulocyte elastase on bacterial suspensions.
Topics: Alanine; Bacillus subtilis; Bacteriolysis; Cell Wall; Chymotrypsin; Humans; Ketones; Leukocytes; Micrococcus; Muramidase; Pancreas; Pancreatic Elastase; Peptides; Peptidoglycan; Spectrophotometry; Staphylococcus; Trypsin | 1973 |
The enzymatic degradation of angiotensin II analogues by proteolytic enzyme in vitro.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Angiotensin II; Biodegradation, Environmental; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyclohexanecarboxylic Acids; Cyclopentanes; Drug Antagonism; Leucyl Aminopeptidase; Peptide Hydrolases; Peptides; Phenylalanine; Structure-Activity Relationship | 1972 |
Amino acid sequence of an alkaline proteinase inhibitor (Streptomyces subtilisin inhibitor) from Streptomyces albogriseolus S-3253.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin; Cyanogen Bromide; Leucine; Methylation; Microbial Collagenase; Proline; Streptomyces; Subtilisins; Thermolysin; Threonine; Trypsin; Trypsin Inhibitors | 1974 |
[Isolation of peptides containing "reactive" lysine residues from D-amino acid oxidase].
Topics: Alanine; Amino Acids; Ammonium Sulfate; Animals; Binding Sites; Borohydrides; Carbon Isotopes; Catalysis; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; D-Amino-Acid Oxidase; Electrophoresis, Paper; Ethanol; Guanidines; Kidney; Lysine; Oxidation-Reduction; Peptides; Protein Binding; Protein Denaturation; Swine; Trypsin | 1972 |
The existence of multiple conformational forms in anhydrochymotrypsin.
Topics: Acetophenones; Alanine; Alkylation; Binding Sites; Chymotrypsin; Circular Dichroism; Dialysis; Drug Stability; Freeze Drying; Kinetics; Methionine; Nitro Compounds; Plants; Protein Binding; Protein Conformation; Serine; Spectrophotometry, Ultraviolet; Time Factors; Trypsin Inhibitors | 1974 |
p-Nitrophenylalanine, p-azidophenylalanine, m-azidophenylalanine, and o-nitro-p-azido-phenylalanine as photoaffinity labels.
Topics: Alanine; Azides; Binding Sites; Chymotrypsin; Hydrogen-Ion Concentration; Kinetics; Nitro Compounds; Nitrophenols; Phenols; Phenylalanine; Photochemistry; Protein Binding; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tritium | 1974 |
Biochemical studies on germination of bacterial spores. I. Incorporation of 14C-L-alanine into spores of Bacillus thiaminolyticus during germination.
Topics: Alanine; Bacillus; Carbon Radioisotopes; Cell Fractionation; Cell Wall; Chromatography; Chymotrypsin; Muramidase; Pronase; Spores, Bacterial; Stereoisomerism; Time Factors; Trichloroacetic Acid; Trypsin | 1974 |
Conformational states of chymotrypsin at high pH: substrate activation and sidechain interactions.
Topics: Alanine; Benzyl Compounds; Chymotrypsin; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Leucine; Mathematics; Protein Binding; Protein Conformation | 1974 |
Amino acid sequence of the alanyl peptide from cyanogen bromide cleavage of bovine plasma albumin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminopeptidases; Animals; Carboxypeptidases; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanogen Bromide; Electrophoresis, Paper; Hydrogen-Ion Concentration; Peptide Fragments; Serum Albumin, Bovine; Spectrophotometry; Subtilisins; Thermolysin; Trypsin | 1974 |
Structure of haemoglobin Seattle.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Chromatography, Gel; Chymotrypsin; Hemoglobins, Abnormal; Humans; Peptides | 1973 |
Rat-proinsulin C-peptides. Amino-acid sequences.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Glutamine; Glycine; Papain; Pepsin A; Peptides; Proinsulin; Proline; Rats; Threonine; Trypsin | 1972 |
The amino acids of the cell wall of Mycobacterium tuberculosis var. bovis, strain BCG. Presence of a poly(L-glutamic acid).
Topics: Acetylation; Alanine; Amino Acids; Bacterial Proteins; Cell Wall; Chromatography, Gel; Chymotrypsin; Glutamates; Hydrolysis; Mass Spectrometry; Methylation; Muramidase; Mycobacterium tuberculosis; Peptidoglycan; Pimelic Acids; Species Specificity; Trypsin | 1973 |
The tryptic peptides and terminal sequences of the protein from the cowpea strain of tobacco mosaic virus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Hydrolysis; Peptides; Plant Diseases; Plants, Edible; Protein Denaturation; Threonine; Tobacco Mosaic Virus; Trypsin; Tyrosine; Viral Proteins | 1972 |
Primary structures of the proinsulin connecting peptides of the rat and the horse.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Ethanol; Glutamates; Glycine; Horses; Hydrogen-Ion Concentration; Pancreas; Peptides; Proinsulin; Proline; Rats; Solubility; Species Specificity; Thiocyanates | 1972 |
Conformational states of aminoacyl residues of proteins. Main polypeptide chain.
Topics: Acetamides; Alanine; Amides; Chymotrypsin; Dipeptides; Drug Stability; Glycine; Methylamines; Muramidase; Myoglobin; Protein Conformation; Proteins; X-Ray Diffraction | 1972 |
A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin.
Topics: Acylation; Alanine; Animals; Binding Sites; Catalysis; Cattle; Chymotrypsin; Hydrogen; Lysine; Models, Chemical; Pancreas; Protein Conformation; Trypsin; Trypsin Inhibitors; Water; X-Ray Diffraction | 1972 |
Determination of the ionization constants and reactivities of the amino-termini of -chymotrypsin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Autoradiography; Carbon Isotopes; Cattle; Chymotrypsin; Cystine; Electric Conductivity; Electrophoresis; Hydrogen-Ion Concentration; Isoleucine; Peptide Chain Termination, Translational; Protein Conformation; Tritium | 1972 |
Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.
Topics: Acylation; Alanine; Anilides; Benzoates; Binding, Competitive; Chemical Phenomena; Chemistry; Chymotrypsin; Dimethylformamide; Electrophoresis, Paper; Esters; Glycine; Hydrazines; Hydrolysis; Kinetics; Mathematics; Methyl Ethers; Nitrobenzenes; Osmolar Concentration; Peptides; Phenylalanine; Quaternary Ammonium Compounds; Structure-Activity Relationship; Thermodynamics; Tritium | 1973 |
Preparation and kinetic properties of a new form of chymotrypsin which is active at alkaline pH: 1 -chymotrypsin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Binding, Competitive; Buffers; Cattle; Chemical Phenomena; Chemistry; Chromatography, Affinity; Chymotrypsin; Chymotrypsinogen; Drug Stability; Enzyme Activation; Esters; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Structure-Activity Relationship; Threonine | 1973 |
Hybrid formation between collagen and synthetic polypeptides.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Glycine; Hybridization, Genetic; Molecular Conformation; Molecular Weight; Optical Rotation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Rabbits; Serine; Skin; Temperature; Tropomyosin | 1973 |
Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Structural; Phenylalanine; Protein Binding; Protein Conformation; Serine; Tyrosine; Uranium; X-Ray Diffraction | 1973 |
Comparison of trypsin activated by alkylammonium ions and alpha-chymotrypsin.
Topics: Acetates; Alanine; Chromatography, Thin Layer; Chymotrypsin; Enzyme Activation; Ethylamines; Glycine; Hydrogen-Ion Concentration; Kinetics; Mathematics; Methylamines; Potassium Chloride; Propylamines; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Trypsin; Trypsin Inhibitors; Valine | 1973 |
Mechanism of action of naturally occurring proteinase inhibitors. Studies with anhydrotrypsin and anhydrochymotrypsin purified by affinity chromatography.
Topics: Alanine; Binding Sites; Binding, Competitive; Borohydrides; Carbon Radioisotopes; Chromatography, Affinity; Chymotrypsin; Circular Dichroism; Egg Proteins; Glycine max; Hydrogen-Ion Concentration; Hydrolysis; Mucoproteins; Oxidation-Reduction; Pancreas; Plants; Protein Denaturation; Serine; Spectrophotometry, Ultraviolet; Tritium; Trypsin; Trypsin Inhibitors | 1974 |
Covalent structure of calf-thymus ALK-histone.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Electrophoresis, Disc; Electrophoresis, Paper; Histones; Leucine; Lysine; Molecular Weight; Peptide Fragments; Protein Conformation; Thermolysin; Thymus Gland; Trypsin | 1974 |
The significance of the N-acyl residue of L-alanyl-L-alanyl-L-alanine p-nitroanilide for cleavage by pancreatic elastase.
Topics: Acylation; Alanine; Anilides; Animals; Binding Sites; Chromatography, Thin Layer; Chymotrypsin; Kinetics; Nitro Compounds; Pancreas; Pancreatic Elastase; Protein Binding; Structure-Activity Relationship; Swine; Trypsin | 1974 |
Studies on the structure of collagen. II. The nature of the N- and C-terminals in enzyme-treated and untreated collagen.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cattle; Chymotrypsin; Collagen; Glycine; Hydrazines; Indicators and Reagents; Leucine; Lysine; Naphthalenes; Nitrobenzenes; Pepsin A; Peptide Hydrolases; Phenylalanine; Skin | 1967 |
The structure of bovine proinsulin.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis; Insulin; Islets of Langerhans; Pepsin A; Peptides; Polymers; Species Specificity; Sulfides; Swine; Trypsin | 1971 |
Amino acid sequence of porcine neurophysin-I.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Disulfides; Electrophoresis, Paper; Formates; Hydrochloric Acid; Hydrolysis; Kinetics; Leucine; Oxidation-Reduction; Papain; Pepsin A; Peptides; Phenylalanine; Pituitary Gland, Posterior; Swine; Trypsin | 1971 |
A comparative structural study on the hemoglobins in Macaca speciosa.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Protein Electrophoresis; Chromatography; Chymotrypsin; Female; Globins; Glycine; Haplorhini; Hemoglobins; Humans; Isoelectric Focusing; Male; Peptides; Time Factors; Trypsin | 1970 |
Optical activity of polypeptides and proteins.
Topics: Alanine; Chymotrypsin; Collagen; Models, Chemical; Muramidase; Myoglobin; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Ribonucleases; Spectrum Analysis | 1972 |
A comparison of the utilization of methyl and p-nitrophenyl esters in determining the specificity of -chymotrypsin.
Topics: Acetates; Alanine; Catalysis; Chymotrypsin; Glycine; Hydrolysis; Kinetics; Leucine; Methanol; Nitrophenols; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Valine | 1972 |
The difference between alpha-and delta-chymotrypsins. Preparation and alkaline pH dependence of alpha1-chymotrypsin-catalyzed hydrolysis of N-acetyl-L-tryptophan methyl ester (ATME). The involement of alanine-149 in alpha-chymotrypsin catalysis.
Topics: Acetates; Alanine; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Esters; Hydrogen-Ion Concentration; Hydrolysis; Tryptophan | 1971 |
Egg white avidin. 3. Sequence of the 78-residue middle cyanogen bromide peptide. Complete amino acid sequence of the protein subunit.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chickens; Chymotrypsin; Cyanides | 1971 |
Investigations on the standardization, assay and action of elastase.
Topics: Alanine; Animals; Benzoates; Blood; Chymotrypsin; Drug Synergism; Elastin; Fluorometry; Hydrogen-Ion Concentration; Kinetics; Macroglobulins; Methods; Pancreas; Pancreatic Elastase; Spectrophotometry; Swine; Trypsin; Trypsin Inhibitors; Ultraviolet Rays | 1971 |
Changes in conformation of insolubilized trypsin and chymotrypsin, followed by fluorescence.
Topics: Alanine; Binding Sites; Carboxylic Acids; Chymotrypsin; Cyanogen Bromide; Hot Temperature; Hydrogen-Ion Concentration; Mathematics; Naphthalenes; Peptides; Polysaccharides; Protein Binding; Protein Conformation; Protein Denaturation; Solubility; Spectrometry, Fluorescence; Sulfonic Acids; Temperature; Toluidines; Trypsin; Trypsin Inhibitors; Tryptophan; Urea | 1971 |
The similarity of trypsin activated by alkylammonium ions, to -chymotrypsin.
Topics: Acetates; Alanine; Chymotrypsin; Enzyme Activation; Ethanol; Glycine; Kinetics; Protein Binding; Protein Conformation; Quaternary Ammonium Compounds; Trypsin; Valine | 1971 |
Acetic and propionic acid production from gamma-irradiated dry proteins.
Topics: Acetates; Alanine; Chromatography, Gas; Chymotrypsin; Cobalt Isotopes; Fibroins; Glycine; Propionates; Proteins; Radiation Effects | 1970 |
Acetyl-L-alanyl-L-alanyl-L-alanine methyl ester: a new highly specific elastase substrate.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Enzyme Precursors; Esters; Hydrogen-Ion Concentration; Kinetics; Pancreatic Elastase; Peptides; Swine; Trypsin | 1970 |
Studies of the structure of freezing point-depressing glycoproteins from an Antarctic fish.
Topics: Alanine; Amino Acids; Aminobutyrates; Anhydrides; Animals; Carboxypeptidases; Chemical Phenomena; Chemistry; Chymotrypsin; Cold Temperature; Disaccharides; Fishes; Freezing; Galactosidases; Glycoproteins; Leucyl Aminopeptidase; Oligosaccharides; Oxidation-Reduction; Peptide Hydrolases; Sodium Hydroxide; Threonine; Trypsin | 1970 |
The conformational energy map of an alanyl residue preceding proline: a quantum-mechanical approach.
Topics: Alanine; Albumins; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry, Physical; Chymotrypsin; Hemoglobins; Muramidase; Muscle Proteins; Peptides; Proline; Pyrrolidines; Quantum Theory; Ribonucleases; X-Ray Diffraction | 1970 |
Nature of the subunits of human chorionic gonadotropin.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin | 1971 |
Snake venom toxins. Purification, properties, and complete amino acid sequence of two toxins from Ringhals (Hemachatus haemachatus) venom.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Chromatography; Chromatography, DEAE-Cellulose; Chymotrypsin | 1971 |
Molecular orbital calculations on the conformation of polypeptides and proteins. VII. Refined calculations on the alanyl residue.
Topics: Alanine; Albumins; Carboxypeptidases; Chymotrypsin; Dipeptides; Hydrogen; Isoleucine; Leucine; Models, Structural; Muramidase; Myoglobin; Probability; Proteins; Quantum Theory; Ribonucleases; Rotation; Valine | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
A new method for the attachment and support of active enzymes.
Topics: Alanine; Anhydrides; Centrifugation; Chemical Phenomena; Chemistry; Chymotrypsin; Enzymes; Glutamates; Methods; Polymers; Solubility; Trypsin | 1968 |
A model of alpha-helical distribution in proteins.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin; Glutamates; Hemoglobins; Leucine; Models, Chemical; Muramidase; Myoglobin; Proteins; Ribonucleases; Valine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Statistical analysis of the distribution of amino acid residues among helical and non-helical regions in globular proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chymotrypsin; Hemoglobins; Leucine; Muramidase; Myoglobin; Papain; Proline; Proteins; Ribonucleases; Statistics as Topic | 1969 |
Stereospecific activation of chymotrypsin catalyzed hydrolyses.
Topics: Alanine; Arginine; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Hippurates; Quaternary Ammonium Compounds | 1966 |
Haemoglobin J Tongariki (alpha-115 alanine--aspartic acid): the first new haemoglobin variant found in a Pacific (Melanesian) population.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Chromatography; Chymotrypsin; Electrophoresis; Female; Genetics, Medical; Hemoglobins; Humans; Male; Pacific Islands; Peptides | 1967 |
Transition state affinity jump chromatography. A double selection method for isolating catalytically active enzymes and other molecules.
Topics: Alanine; Chromatography, Affinity; Chymotrypsin; Enzymes, Immobilized; Serine; Tritium | 1980 |
Acylation of the alanine149 N-terminal of alpha-chymotrypsin and its effect on catalytic function.
Topics: Acylation; Alanine; Chemical Phenomena; Chemistry; Chymotrypsin; Chymotrypsinogen; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Structure-Activity Relationship; Trypsin | 1982 |
The role of amino-terminal alanine in the control of conformation and activity of alpha-chymotrypsin.
Topics: Alanine; Amino Acid Sequence; Chymotrypsin; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Protein Denaturation | 1982 |
Inhibition of trypsin with active-site-directed enzyme-activated nitrosoamide substrates.
Topics: Acylation; Alanine; Benzamides; Binding Sites; Binding, Competitive; Chymotrypsin; Drug Stability; Hydrolysis; Lysine; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrosamines; Nitroso Compounds; Structure-Activity Relationship; Trypsin; Trypsin Inhibitors | 1995 |
Functional linkage between the active site of alpha-lytic protease and distant regions of structure: scanning alanine mutagenesis of a surface loop affects activity and substrate specificity.
Topics: Alanine; Aspartic Acid Endopeptidases; Binding Sites; Chymotrypsin; Endopeptidases; Kinetics; Molecular Structure; Mutagenesis; Mutation; Pancreatic Elastase; Protein Conformation; Protein Engineering; Serine Endopeptidases; Streptomyces griseus; Structure-Activity Relationship; Substrate Specificity; Trypsin | 1995 |
Inhibition of alpha-chymotrypsin with an enzyme-activated n-nitrosoamide: active-site labeling by the naphthylmethyl cation.
Topics: Alanine; Alkylation; Amino Acid Sequence; Binding Sites; Cations; Chymotrypsin; In Vitro Techniques; Indicators and Reagents; Models, Chemical; Molecular Sequence Data; Molecular Structure; Nitroso Compounds; Spectrometry, Mass, Fast Atom Bombardment | 1995 |
Labeling of the active site of alpha-chymotrypsin with N-nitroso-N-benzylacetamide and related compounds.
Topics: Acetamides; Alanine; Benzeneacetamides; Benzyl Compounds; Binding Sites; Chymotrypsin; Magnetic Resonance Spectroscopy; Nitroso Compounds; Phenylalanine; Structure-Activity Relationship | 1993 |
Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue.
Topics: Alanine; Chymotrypsin; Crystallography, X-Ray; Glycine; Hordeum; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Structure, Secondary; Proteins; Recombinant Proteins; Structure-Activity Relationship; Surface Properties; Water | 1994 |
Temperature-dependent conformational change of bacteriorhodopsin as studied by solid-state 13C NMR.
Topics: Alanine; Amino Acid Sequence; Bacteriorhodopsins; Carbon Isotopes; Chymotrypsin; Freezing; Halobacterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Microscopy, Electron; Models, Structural; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Protein Structure, Secondary; Temperature; Thermodynamics | 1996 |
Alanine point-mutations in the reactive region of bovine pancreatic trypsin inhibitor: effects on the kinetics and thermodynamics of binding to beta-trypsin and alpha-chymotrypsin.
Topics: Alanine; Animals; Aprotinin; Binding Sites; Calorimetry; Cattle; Chymotrypsin; Circular Dichroism; Enzyme Stability; Escherichia coli; Kinetics; Point Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Thermodynamics; Trypsin | 1996 |
Strain in the folding nucleus of chymotrypsin inhibitor 2.
Topics: Alanine; Chymotrypsin; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Folding; Serine Proteinase Inhibitors; Thermodynamics | 1997 |
Endopeptidase activities of selected Porphyromonas spp., Prevotella spp. and Fusobacterium spp. of oral and non-oral origin.
Topics: Alanine; Aminopeptidases; Bacteroides; Chymotrypsin; Coumarins; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Fluorescent Dyes; Fusobacterium; Fusobacterium necrophorum; Humans; Indicators and Reagents; Lysine; Mouth; Oligopeptides; Pancreatic Elastase; Phenylalanine; Porphyromonas; Porphyromonas gingivalis; Prevotella; Proline; Tyrosine; Virulence | 1997 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; ATP-Dependent Proteases; Bacterial Proteins; Chymotrypsin; DNA-Directed DNA Polymerase; Escherichia coli; Escherichia coli Proteins; Half-Life; Heat-Shock Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protease La; Protein Conformation; Protein Processing, Post-Translational; Rec A Recombinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; SOS Response, Genetics; Substrate Specificity | 1998 |
The differential specificity of chymotrypsin A and B is determined by amino acid 226.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cattle; Chymotrypsin; Glycine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phenylalanine; Protein Isoforms; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; Substrate Specificity; Tryptophan; Tyrosine | 1999 |
Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase.
Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Chymotrypsin; Conserved Sequence; COS Cells; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Humans; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Triphosphatase; Protein Folding; Sodium Azide; Transfection; Triazines; Tryptophan | 1999 |
Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.
Topics: Alanine; Amino Acids; Animals; Aprotinin; Binding Sites; Cattle; Chymotrypsin; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Serpins; Substrate Specificity; Thermodynamics; Trypsin Inhibitor, Kazal Pancreatic; Turkeys | 1999 |
Conformation of the primary binding loop folded through an intramolecular interaction contributes to the strong chymotrypsin inhibitory activity of the chymotrypsin inhibitor from Erythrina variegata seeds.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Caseins; Chymotrypsin; Erythrina; Kinetics; Mutation; Plant Proteins; Plants, Medicinal; Protein Conformation; Protein Folding; Recombinant Proteins; Seeds; Serine Proteinase Inhibitors; Surface Plasmon Resonance | 1999 |
The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position.
Topics: Alanine; Antithrombins; Arginine; Chymotrypsin; Drug Design; Factor Xa Inhibitors; Fibrinolysin; Kallikreins; Models, Molecular; Molecular Structure; Pipecolic Acids; Serine Proteinase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiazoles; Thrombin; Trypsin | 2000 |
The design and synthesis of thrombin inhibitors: the introduction of in vivo efficacy and oral bioavailability into benzthiazolylalanine inhibitors.
Topics: Administration, Oral; Alanine; Animals; Antithrombins; Biological Availability; Chymotrypsin; Drug Design; Fibrinolysin; Kinetics; Molecular Conformation; Molecular Structure; Partial Thromboplastin Time; Structure-Activity Relationship; Sulfonamides; Thiazoles; Thrombosis; Trypsin | 2000 |
Amino acid sequence of the protease inhibitor BWI-4a from buckwheat seeds.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Chymotrypsin; Disulfides; Fagopyrum; Glycine; Leucine; Mass Spectrometry; Molecular Sequence Data; Peptides; Plant Proteins; Protein Isoforms; Pyrrolidonecarboxylic Acid; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Trypsin Inhibitors | 2000 |
Direct comparison of experimental and calculated folding free energies for hydrophobic deletion mutants of chymotrypsin inhibitor 2: free energy perturbation calculations using transition and denatured states from molecular dynamics simulations of unfoldi
Topics: Alanine; Amino Acid Substitution; Chymotrypsin; Computer Simulation; Glycine; Hordeum; Isoleucine; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Denaturation; Protein Folding; Reproducibility of Results; Serine Proteinase Inhibitors; Thermodynamics; Valine | 2001 |
Thermodynamic quantitative structure-activity relationship analysis for enzyme-ligand interactions in aqueous phosphate buffer and organic solvent.
Topics: Alanine; Chymotrypsin; Esters; Pentanols; Phosphates; Quantitative Structure-Activity Relationship; Solvents; Thermodynamics | 2001 |
Analysis of serine proteinase-inhibitor interaction by alanine shaving.
Topics: Alanine; Animals; Aprotinin; Binding Sites; Calorimetry; Cattle; Chymotrypsin; Circular Dichroism; Enzyme Stability; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine Proteinase Inhibitors; Thermodynamics; Trypsin | 2002 |
[The probable existence of a chymotrypsin lacking an N-terminal alanine molecule].
Topics: Alanine; Chymotrypsin; Endopeptidases; Enzyme Precursors; Hydrolases; Peptide Hydrolases; Probability | 1954 |
THE INHIBITORY EFFECT OF OMEGA-AMINO ACIDS AND GUANIDINO ACIDS ON THE ACTIVATION OF ALPHA-CHYMOTRYPSINOGEN AND TRYPSINOGEN.
Topics: Alanine; Amidines; Amino Acids; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Caseins; Chymotrypsin; Chymotrypsinogen; Enzyme Inhibitors; Enzyme Precursors; Guanidine; Guanidines; Levulinic Acids; Pharmacology; Research; Trypsin; Trypsinogen | 1963 |
ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE.
Topics: Alanine; Chymotrypsin; Proteins; Research; Serine | 1963 |
FURTHER STUDIES OF RADIATION EFFECTS ON THE PROTEINS AND THEIR CONSTITUENTS.
Topics: Alanine; Amino Acids; Animals; Caseins; Cattle; Chemistry Techniques, Analytical; Chymotrypsin; Collagen; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Gelatin; Glycine; Histones; Muramidase; Ovalbumin; Pepsin A; Proteins; Radiation Effects; Ribonucleases; Serum Albumin; Serum Albumin, Bovine; Temperature; Zein | 1964 |
MUTATIONALLY INDUCED AMINO ACID SUBSTITUTIONS IN A TRYPTIC PEPTIDE OF THE TRYPTOPHAN SYNTHETASE A PROTEIN.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Biochemical Phenomena; Biochemistry; Carboxypeptidases; Chromatography; Chromosome Mapping; Chymotrypsin; Escherichia coli; Genetic Code; Glycine; Hydro-Lyases; Isoleucine; Leucyl Aminopeptidase; Molecular Biology; Mutation; Papain; Peptides; Protein Hydrolysates; Research; Serine; Trypsin; Tryptophan Synthase | 1965 |
OPHIDIAN L-AMINO ACID OXIDASE. THE NATURE OF THE ENZYME-SUBSTRATE COMPLEXES.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Biochemical Phenomena; Biochemistry; Catalysis; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Glycine; Hydroquinones; Kinetics; L-Amino Acid Oxidase; Phenylalanine; Research; Snakes; Tryptophan; Venoms | 1965 |
Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Benzamidines; Chymotrypsin; Chymotrypsinogen; Glycine; Kinetics; Molecular Sequence Data; Mutation; Peptide Hydrolases; Protein Conformation; Rats; Serine; Substrate Specificity; Trypsin; Trypsin Inhibitors | 2004 |
On the rational design of substrate mimetics: The function of docking approaches for the prediction of protease specificities.
Topics: Alanine; Amino Acids, Aromatic; Binding Sites; Catalysis; Chymotrypsin; Computer Simulation; Endopeptidases; Esters; Hydrogen Bonding; Hydrolysis; Kinetics; Models, Molecular; Molecular Conformation; Molecular Structure; Static Electricity; Substrate Specificity; Subtilisin; Thermodynamics | 2004 |
The contribution of key hydrophobic residues in ecotin to enzyme-inhibitor complex stability.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Chymotrypsin; Enzyme Stability; Escherichia coli Proteins; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Sequence Data; Mutation; Pancreatic Elastase; Periplasmic Proteins; Serine Proteinase Inhibitors; Trypsin Inhibitors | 2009 |
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives.
Topics: Alanine; Chymotrypsin; Enzyme Inhibitors; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2012 |
The formation of biodegradable micelles from a therapeutic initiator for enzyme-mediated drug delivery.
Topics: Alanine; Chymotrypsin; Dopamine; Drug Delivery Systems; Hydrolysis; Micelles; Pancreatic Elastase; Peptides; Phenylalanine; Polymerization; Sarcosine; Thermolysin | 2015 |
Identification of lanthionine and lysinoalanine in heat-treated wheat gliadin and bovine serum albumin using tandem mass spectrometry with higher-energy collisional dissociation.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Cysteine; Cystine; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Proteolysis; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Triticum; Trypsin | 2016 |