alanine and alafosfalin

alanine has been researched along with alafosfalin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199021 (77.78)18.7374
1990's0 (0.00)18.2507
2000's2 (7.41)29.6817
2010's3 (11.11)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Allen, JG; Atherton, FR; Hall, MJ; Hassall, CH; Holmes, SW; Lambert, RW; Nisbet, LJ; Ringrose, PS1
Allen, JG; Havas, L; Leicht, E; Lenox-Smith, I; Nisbet, LJ1
Arisawa, M; Maruyama, HB; Sawada, T1
Atherton, FR; Hall, MJ; Hassall, CH; Lambert, RW; Lloyd, WJ; Ringrose, PS1
Atherton, FR; Hassall, CH; Lambert, RW1
Poliak, MS1
Kafarski, P; Lejczak, B; Mastalerz, P; Sztajer, H1
Giovenella, AJ; Grappel, SF; Nisbet, LJ1
Gibson, MM; Higgins, CF; Price, M1
Angehrn, P; Hall, MJ; Lloyd, WJ; Westmacott, D1
Neuman, M1
Hall, MJ; Middleton, RF; Westmacott, D1
Andrews, JM; Dean, S; Kendall, MJ; Welling, PG; Wise, R1
Mhalu, FS; O'Grady, F; Pearson, NJ; Towner, KJ1
Traub, WH1
Atherton, FR; Hall, MJ; Hassall, CH; Holmes, SW; Lambert, RW; Lloyd, WJ; Ringrose, PS1
Atherton, FR; Hall, MJ; Hassall, CH; Holmes, SW; Lambert, RW; Lloyd, WJ; Nisbet, LJ; Ringrose, PS; Westmacott, D1
Cars, O; Henning, C1
Arisawa, M; Maruyama, HB; Ohsawa, E; Ohshima, J1
Hahn, FE1
Allen, JG; Lees, LJ1
Boissier, E; Freydière, AM; Gould, FK; Ouedraogo, RT; Perez, JM; Perry, JD; Riley, G1
Brandsch, M; Bruch, M; Gebauer, S; Neumann, J1
Doki, S; Hattori, M; Ishitani, R; Iwaki, M; Iwase, N; Kandori, H; Kato, HE; Koyama, M; Newstead, S; Nureki, O; Solcan, N; Sugita, Y; Tsukazaki, T1
Guettou, F; Jegerschöld, C; Jong, AJ; Löw, C; Moberg, P; Nordlund, P; Quistgaard, EM; Trésaugues, L; Zhu, L1
Bougioukou, DJ; Mukherjee, S; Peck, SC; Ting, CP; van der Donk, WA1
Howe, Z; Huesgen, E; Moore, SE1

Reviews

1 review(s) available for alanine and alafosfalin

ArticleYear
[Antibiotics of the phosphonic acid group].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:1

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacterial Infections; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fosfomycin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests

1987

Trials

1 trial(s) available for alanine and alafosfalin

ArticleYear
Pharmacokinetics of alafosfalin, alone and in combination with cephalexin, in humans.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:6

    Topics: Alanine; Cell Wall; Cephalexin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Female; Food; Humans; Hydrolysis; Kinetics; Male; Peptides; Phosphopeptides; Time Factors; Urinary Tract Infections

1980

Other Studies

25 other study(ies) available for alanine and alafosfalin

ArticleYear
Phosphonopeptides as antibacterial agents: alaphosphin and related phosphonopeptides.
    Antimicrobial agents and chemotherapy, 1979, Volume: 15, Issue:5

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Culture Media; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Microbial Sensitivity Tests; Organophosphorus Compounds; Peptide Hydrolases; Phosphopeptides; Rats; Sepsis

1979
Phosphonopeptides as antibacterial agents: metabolism and pharmacokinetics of alafosfalin in animals and humans.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:3

    Topics: Alanine; Animals; Anti-Infective Agents; Biotransformation; Female; Haplorhini; Humans; Kinetics; Male; Papio; Phosphopeptides; Protein Binding; Rats; Time Factors; Tissue Distribution

1979
Alafosfalin, a new inhibitor of cell wall biosynthesis: in vitro activity against urinary isolates in Japan and potentiation with beta-lactams.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Bacteria; Bacteriuria; beta-Lactams; Cell Wall; Drug Resistance, Microbial; Drug Synergism; Humans; Japan; Microbial Sensitivity Tests; Phosphopeptides

1979
Phosphonopeptides as antibacterial agents: mechanism of action of alaphosphin.
    Antimicrobial agents and chemotherapy, 1979, Volume: 15, Issue:5

    Topics: Alanine; Alanine Racemase; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Cell Wall; DNA, Bacterial; Organophosphorus Compounds; Phosphopeptides; RNA, Bacterial; Uridine Diphosphate

1979
Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:1

    Topics: Alanine; Aminoethylphosphonic Acid; Animals; Anti-Bacterial Agents; Bacteria; Biological Transport, Active; Chemical Phenomena; Chemistry; Escherichia coli; Escherichia coli Infections; Haemophilus influenzae; Mice; Organophosphonates; Organophosphorus Compounds; Peptides; Streptococcus; Structure-Activity Relationship

1986
Antibacterial activity of phosphono dipeptides related to alafosfalin.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:11

    Topics: Alanine; Anti-Bacterial Agents; Bacteria; Dipeptides; Structure-Activity Relationship

1986
Activity of a peptidyl prodrug, alafosfalin, against anaerobic bacteria.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:6

    Topics: Alanine; Anti-Bacterial Agents; Bacteria, Anaerobic; Culture Media; Cycloserine; Microbial Sensitivity Tests; Penicillin G

1985
Genetic characterization and molecular cloning of the tripeptide permease (tpp) genes of Salmonella typhimurium.
    Journal of bacteriology, 1984, Volume: 160, Issue:1

    Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; DNA Restriction Enzymes; DNA Transposable Elements; Drug Resistance, Microbial; Genes; Genes, Bacterial; Genotype; Membrane Transport Proteins; Mutation; Phenotype; Salmonella typhimurium

1984
Synergistic antibacterial activity between L-norvalyl-L-1-aminoethylphosphonic acid and nocardicin A.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:5

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacteriolysis; Drug Synergism; Gram-Negative Bacteria; Lactams; Mice; Microbial Sensitivity Tests; Proteus mirabilis; Pseudomonas aeruginosa; Sepsis

1984
Recent developments in the field of phosphonic acid antibiotics.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14, Issue:4

    Topics: Alanine; Animals; Anti-Bacterial Agents; Fosfomycin; Humans

1984
The fractional inhibitory concentration (FIC) index as a measure of synergy.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 11, Issue:5

    Topics: Alanine; Anti-Bacterial Agents; Bacteria; Cephalexin; Drug Synergism; Microbial Sensitivity Tests

1983
Effect of food on the bioavailability of alafosfalin, a new antibacterial agent.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:3

    Topics: Administration, Oral; Adult; Alanine; Animals; Anti-Infective Agents; Biological Availability; Dietary Proteins; Female; Food; Humans; Intestinal Absorption; Kinetics; Male; Milk; Models, Biological; Phosphopeptides; Water

1980
Resistance to antimicrobial agents of Vibrio cholerae E1 Tor strains isolated during the fourth cholera epidemic in the United Republic of Tanzania.
    Bulletin of the World Health Organization, 1980, Volume: 58, Issue:5

    Topics: Alanine; Anti-Bacterial Agents; Cholera; Drug Resistance, Microbial; Extrachromosomal Inheritance; Humans; Tanzania; Vibrio cholerae

1980
In vitro evaluation of alaphosphin (Ro 03-7008) against Serratia marcescens.
    Chemotherapy, 1980, Volume: 26, Issue:2

    Topics: Alanine; Anti-Bacterial Agents; Carbenicillin; Cefamandole; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Penicillin Resistance; Phosphopeptides; Serratia marcescens

1980
Phosphonopeptide antibacterial agents related to alafosfalin: design, synthesis, and structure-activity relationships.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:6

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacteria; Dipeptides; Escherichia coli Infections; Mice; Microbial Sensitivity Tests; Phosphopeptides; Structure-Activity Relationship

1980
Antibacterial properties of alafosfalin combined with cephalexin.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:4

    Topics: Alanine; Amdinocillin; Ampicillin; Anti-Bacterial Agents; Bacteria; Bacteriolysis; Cephalexin; Drug Synergism; Escherichia coli; Salmonella typhimurium; Staphylococcus; Streptococcus

1981
Penetration of alafosfalin and ampicillin into tissue cage fluid in rabbits.
    Chemotherapy, 1982, Volume: 28, Issue:3

    Topics: Alanine; Ampicillin; Animals; Anti-Infective Agents; Body Fluids; Kinetics; Models, Biological; Rabbits; Time Factors

1982
In vitro potentiation of cephalosporins by alafosfalin against urinary tract bacteria.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:5

    Topics: Alanine; Ampicillin; Anti-Bacterial Agents; Cephalosporins; Drug Combinations; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillin G; Species Specificity; Urinary Tract Infections

1982
Alafosfalin, a new synthetic antibacterial compound.
    Die Naturwissenschaften, 1981, Volume: 68, Issue:2

    Topics: Alanine; Anti-Bacterial Agents; Bacteria; Drug Evaluation, Preclinical; Phosphopeptides; Species Specificity

1981
Alafosfalin as a selective agent for isolation of salmonella from clinical samples.
    Journal of clinical microbiology, 2002, Volume: 40, Issue:11

    Topics: Alanine; Bacteriological Techniques; Chromogenic Compounds; Culture Media; Drug Resistance, Bacterial; Feces; Gram-Negative Bacteria; Humans; Salmonella; Sensitivity and Specificity

2002
Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells.
    European journal of biochemistry, 2004, Volume: 271, Issue:10

    Topics: Alanine; Animals; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Carrier Proteins; Cell Line; Dipeptides; Electrophysiology; Epithelial Cells; Humans; Intestinal Mucosa; Intestines; Intracellular Space; Kidney; Peptide Transporter 1; Rats; Symporters

2004
Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-09, Volume: 110, Issue:28

    Topics: Alanine; Carrier Proteins; Ion Transport; Models, Molecular; Molecular Dynamics Simulation; Peptides; Protein Conformation; Protons

2013
Structural insights into substrate recognition in proton-dependent oligopeptide transporters.
    EMBO reports, 2013, Volume: 14, Issue:9

    Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Molecular Docking Simulation; Molecular Sequence Data; Protein Binding; Shewanella; Symporters

2013
Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin.
    Organic & biomolecular chemistry, 2019, 01-23, Volume: 17, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Biocatalysis; Leucine-tRNA Ligase; Molecular Conformation; Streptomyces

2019
Sustained virologic suppression with abacavir, emtricitabine, and crushed dolutegravir and tenofovir alafenamide in a patient with HIV and eosinophilic esophagitis.
    International journal of STD & AIDS, 2020, Volume: 31, Issue:3

    Topics: Adult; Alanine; Anti-HIV Agents; Deglutition Disorders; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Eosinophilic Esophagitis; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Male; Oxazines; Piperazines; Pyridones; Tenofovir; Treatment Outcome; Viral Load

2020