alanine has been researched along with 6-cyano-7-nitroquinoxaline-2,3-dione in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (54.55) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, MV; McDonald, JW | 1 |
| Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S | 1 |
| Clifford, DB; Thio, LL; Zorumski, CF | 1 |
| Bockaert, J; Do, E; Manzoni, OJ; Poulat, F; Sahuquet, A; Sassetti, I; Sladeczek, FA | 1 |
| Ito, I; Sugiyama, H | 1 |
| Bernardi, G; Bonci, A; Calabresi, P; Mercuri, NB; Stratta, F | 1 |
| Ebert, B; Krogsgaard-Larsen, P; Lenz, SM; Lund, TM; Madsen, U | 1 |
| Beaver, KM; Hawkins, LM; Jane, DE; Roberts, PJ; Sunter, DC; Taylor, PM | 1 |
| Allen, CN; Lambein, F; Ludolph, AC; Riepe, M; Spencer, PS | 1 |
| Fernández-Sánchez, MT; Novelli, A; Torreblanca, A | 1 |
| Fukunaga, K; Miyamoto, E; Ushio, Y; Yano, S | 1 |
| Hider, RC; Smart, TG; Xie, X | 1 |
| Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Burke, JP; Hablitz, JJ | 1 |
| Kayton, RJ; Roy, DN; Sabri, MI; Spencer, PS | 1 |
| Kagawa, Y; Mikoshiba, K; Yuzaki, M | 1 |
| Magistretti, PJ; Martin, JL; Pellegri, G | 1 |
| Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M | 1 |
| Ahlemeyer, B; Hoffmann, GF; Kölker, S; Krieglstein, J | 1 |
| Darmani, NA; Pandya, DK | 1 |
| Foley, P; Matias, C; Quinta-Ferreira, ME | 1 |
| Che, W; Contractor, A; Green, T; Heinemann, SF; Kamiya, H; Sakai, R; Swanson, GT | 1 |
| Acerbo, MJ; Delius, JD; Gargiulo, PA; Krug, I | 1 |
| Arai, AC; Kessler, M | 1 |
| Dolman, NP; Ghosal, A; Jane, DE; Mayer, ML | 1 |
| Bai, ZT; Chai, ZF; Ji, YH; Jiang, F; Liu, T; Pang, XY | 1 |
| Apland, JP; Aroniadou-Anderjaska, V; Braga, MF | 1 |
| Burdakov, D; Fugger, L; Jensen, LT; Karnani, MM; Venner, A | 1 |
| Landa, M; Peppi, M; Sewell, WF | 1 |
| Ahmed, AH; Holley, SM; Murthy, SE; Nowak, LM; Oswald, RE; Srinivasan, J; Weiland, GA | 1 |
| Ishikura, T; Maruyama, T; Matsuura, T; Ohbuchi, T; Ohkubo, J; Suzuki, H; Ueta, Y; Yoshimura, M | 1 |
| Ceangă, M; Spataru, A; Zăgrean, AM; Zăgrean, L | 1 |
| Andreou, AP; Goadsby, PJ; Holland, PR; Lasalandra, MP | 1 |
33 other study(ies) available for alanine and 6-cyano-7-nitroquinoxaline-2,3-dione
| Article | Year |
|---|---|
Neuroprotective synergism of 2-amino-3-phosphonoproprionate (D,L-AP3) and MK-801 against ibotenate induced brain injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Female; Ibotenic Acid; Injections; Male; Organ Size; Quinoxalines; Rats; Rats, Sprague-Dawley | 1992 |
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus | 1992 |
Effects of bromowillardiine and willardiine on non-N-methyl-D-aspartate receptors in postnatal rat hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Membrane Potentials; Neurons; Pyrimidinones; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Uracil | 1991 |
Pharmacological characterization of the quisqualate receptor coupled to phospholipase C (Qp) in striatal neurons.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Cells, Cultured; Corpus Striatum; Dizocilpine Maleate; Fura-2; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Phorbol 12,13-Dibutyrate; Phosphoserine; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Type C Phospholipases | 1991 |
Roles of glutamate receptors in long-term potentiation at hippocampal mossy fiber synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Perfusion; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1991 |
Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dopamine; Electrophysiology; Female; Glycine; Male; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Tetrodotoxin | 1993 |
Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Membrane; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Isoxazoles; Male; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Structure-Activity Relationship | 1994 |
Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardiine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Male; Pyrimidinones; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Synaptic Membranes; Tritium; Uracil | 1995 |
In vitro toxicological investigations of isoxazolinone amino acids of Lathyrus sativus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Electrophysiology; Hippocampus; Isoxazoles; Lathyrism; Mice; Motor Cortex; Nerve Degeneration; Plants, Toxic | 1995 |
Two components in neurotoxicity by L-2-amino-3-phosphonopropionate in cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Neurons; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Activation of Ca2+/calmodulin-dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Animals, Newborn; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Immunoblotting; Ionomycin; Molecular Weight; Phosphoproteins; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Vimentin | 1994 |
Modulation of GABA-mediated synaptic transmission by endogenous zinc in the immature rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Alanine; Animals; Animals, Newborn; Bicuculline; Cations, Divalent; Chelating Agents; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Histidine; In Vitro Techniques; Iron Chelating Agents; Pyramidal Tracts; Pyridones; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Zinc | 1994 |
Release of [3H]GABA evoked by glutamate agonists from hippocampal slices: effects of dithiothreitol and glutathione.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dithiothreitol; Dizocilpine Maleate; GABA Agonists; gamma-Aminobutyric Acid; Glutathione; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Magnesium; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tritium | 1994 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
beta-Cyano-L-alanine toxicity: evidence for the involvement of an excitotoxic mechanism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Male; Mice; Mitochondria; Neurotoxins; Receptors, Glutamate | 1996 |
Characterization of metabotropic glutamate receptors in cultured Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Ibotenic Acid; Kinetics; Membrane Potentials; Purkinje Cells; Receptors, Metabotropic Glutamate; Time Factors; Virulence Factors, Bordetella | 1993 |
VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Mice; Neuronal Plasticity; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Vasoactive Intestinal Peptide | 1998 |
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; Catheters, Indwelling; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Locomotion; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Synaptic Transmission; Valine | 1999 |
Methylmalonic acid induces excitotoxic neuronal damage in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Survival; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Methylmalonic Acid; Neurons; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Piperidines | 2000 |
Involvement of other neurotransmitters in behaviors induced by the cannabinoid CB1 receptor antagonist SR 141716A in naive mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Head Movements; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Phenols; Piperidines; Psychotropic Drugs; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Serotonin Antagonists; Tachykinins | 2000 |
L-AP3 blocks rises in intracellular calcium associated with hippocampal CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Calcium; Calcium Signaling; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; Hippocampus; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Long-Term Potentiation; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 2002 |
Differential activation of individual subunits in heteromeric kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Humans; Macromolecular Substances; Models, Neurological; Mutagenesis, Site-Directed; Mutation; Neurons; Receptors, Kainic Acid; Synapses; Synaptic Transmission | 2002 |
Cognitive effects of dopaminergic and glutamatergic blockade in nucleus accumbens in pigeons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Benzazepines; Cognition; Columbidae; Cycloleucine; Discrimination Learning; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Glycine; Nucleus Accumbens; Pipecolic Acids; Random Allocation; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT2 Receptor Antagonists; Spiperone | 2005 |
Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Allosteric Site; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membranes; Peptides, Cyclic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tritium | 2006 |
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis | 2006 |
Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Pain; Proline; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scorpion Venoms | 2007 |
Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Amygdala; Animals; Calcium; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures; Soman; Thymine | 2009 |
Direct and indirect control of orexin/hypocretin neurons by glycine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Alanine; Animals; Animals, Newborn; Benzothiadiazines; Chloride Channels; Electrophysiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hypothalamus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, Glutamate; Receptors, Glycine; Strychnine; Synaptic Potentials | 2011 |
Cochlear kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cochlea; Female; Immunohistochemistry; Male; Mice; Mice, Inbred CBA; Receptors, Kainic Acid; RNA, Messenger; Synaptic Transmission | 2012 |
The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Amino Acid Substitution; Binding Sites; Cell Line; Crystallography, X-Ray; Glutamic Acid; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kainic Acid; Protein Binding; Protein Conformation; Protein Stability; Protein Structure, Tertiary; Quisqualic Acid; Receptors, AMPA; Static Electricity | 2012 |
Electrophysiological effects of kainic acid on vasopressin-enhanced green fluorescent protein and oxytocin-monomeric red fluorescent protein 1 neurones isolated from the supraoptic nucleus in transgenic rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; Animals; Arginine Vasopressin; Cell Separation; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; Isoxazoles; Kainic Acid; Luminescent Proteins; Neurons; Oxytocin; Patch-Clamp Techniques; Primary Cell Culture; Propionates; Rats; Rats, Transgenic; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Red Fluorescent Protein; Supraoptic Nucleus; Thymine | 2014 |
The single versus combinatorial effects of MK-801, CNQX, Nifedipine and AP-3 on primary cultures of cerebellar granule cells in an oxygen-glucose deprivation model.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Death; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Drug Therapy, Combination; Fluorescence; Glucose; Nifedipine; Oxygen; Propidium; Rats | 2014 |
Modulation of nociceptive dural input to the trigeminocervical complex through GluK1 kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Alanine; Animals; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Isoquinolines; Male; Meningeal Arteries; Neurons; Nociception; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Thymine; Trigeminal Nuclei | 2015 |