alanine has been researched along with 2-amino-3-phosphonopropionic acid in 126 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (6.35) | 18.7374 |
| 1990's | 99 (78.57) | 18.2507 |
| 2000's | 13 (10.32) | 29.6817 |
| 2010's | 5 (3.97) | 24.3611 |
| 2020's | 1 (0.79) | 2.80 |
| Authors | Studies |
|---|---|
| Li, PP; Vecil, GG; Warsh, JJ | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G; Ravula, R; Wang, J | 1 |
| Hu, GY; Storm, JF | 1 |
| Flagg, SD; Littman, L; Munir, M; Robinson, MB | 1 |
| Conn, PJ; Desai, MA; Smith, TS | 1 |
| Conn, PJ; Winder, DG | 1 |
| Gallagher, JP; Zheng, F | 1 |
| Bockaert, J; Curry, K; Homburger, V; Manzoni, O; Prezeau, L; Sladeczek, F | 1 |
| Bernardi, G; Calabresi, P; Maj, R; Mercuri, NB; Pisani, A | 1 |
| Johnston, MV; McDonald, JW | 1 |
| Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S | 1 |
| Gordon, FJ; Pawloski-Dahm, C | 1 |
| Behnisch, T; Fjodorow, K; Reymann, KG | 1 |
| Crepel, F; Daniel, H; Hemart, N; Jaillard, D | 1 |
| Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| Chattarji, S; Sejnowski, TJ; Stanton, PK | 1 |
| Bockaert, J; Do, E; Manzoni, OJ; Poulat, F; Sahuquet, A; Sassetti, I; Sladeczek, FA | 1 |
| Ito, I; Sugiyama, H | 1 |
| Opitz, T; Reymann, KG | 2 |
| Ito, I; Sugiyama, H; Tanabe, S | 1 |
| Baraban, JM; Stratton, KR; Worley, PF | 1 |
| Bredt, DS; Hwang, PM; Snyder, SH | 1 |
| Johnson, BG; McQuaid, LA; Schoepp, DD; Smith, EC | 1 |
| Collingridge, GL; Irving, AJ; Schofield, JG; Sunter, DC; Watkins, JC | 1 |
| Johnson, BG; Schoepp, DD | 3 |
| Tan, LG; Tan, SA | 1 |
| Aleksandrov, VG; Lapin, IP; Mandel'shtam, IuE; Ryzhov, IV; Slepokurov, MV | 1 |
| Walker, JB; Woznicki, DT | 1 |
| Hosain, F; Lejczak, B; Spencer, RP; Spitznagle, LA; Surh, Y | 1 |
| Collins, JF; Foster, GA; Roberts, PJ; Sharif, NA | 1 |
| Horigane, A; Horiguchi, M; Matsumoto, T | 1 |
| Boccone, L; Greenberg, R; Maiese, K; Swiriduk, M | 1 |
| Caldwell, M; Kelly, JP; Leonard, BE; Maginn, M | 1 |
| Bernardi, G; Bonci, A; Calabresi, P; Mercuri, NB; Stratta, F | 1 |
| Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Akhondzadeh, S; Stone, TW | 2 |
| Saugstad, JA; Segerson, TP; Westbrook, GL | 1 |
| Haun, SE; Horrocks, LA; Lipscomb, DC; Segeleon, JE; Trapp, VL | 1 |
| Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ | 1 |
| Honoré, T; Sheardown, MJ; Suzdak, PD | 1 |
| Evrard, P; Gadisseux, JF; Gressens, P; Marret, S; Mukendi, R | 1 |
| Fernández-Sánchez, MT; Novelli, A; Torreblanca, A | 1 |
| Coderre, TJ; Fundytus, ME | 1 |
| Fukunaga, K; Miyamoto, E; Ushio, Y; Yano, S | 1 |
| Herrero, I; Miras-Portugal, MT; Sánchez-Prieto, J | 1 |
| Bigl, V; Grantyn, R; Rothe, T | 1 |
| Bennett, BM; Goh, JW; Madigan, MA; Musgrave, MA | 1 |
| Littman, L; Robinson, MB | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB; Pisani, A; Stefani, A | 1 |
| Hider, RC; Smart, TG; Xie, X | 1 |
| Berrino, L; Calderaro, V; D'Amico, M; Maione, S; Pizzirusso, A; Rossi, F; Vitagliano, S | 1 |
| Colwell, CS; Levine, MS | 1 |
| Izumi, Y; Zorumski, CF | 1 |
| Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Aronica, E; Balázs, R; Condorelli, DF; Nicoletti, F | 1 |
| Black, IB; Dreyfus, CF; Mount, HT | 1 |
| Abe, K; Saito, H | 1 |
| Ikeda, M | 1 |
| Fix, AS; Griffey, KI; Johnson, JA; Olney, JW; Schoepp, DD; Tizzano, JP; Vestre, WA | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB; Pisani, A | 1 |
| Candeo, P; Favaron, M; Gabellini, N; Manev, H; Manev, RM | 1 |
| Ballyk, BA; Goh, JW; Musgrave, MA | 1 |
| Goh, JW; Musgrave, MA | 1 |
| Bashir, ZI; Berretta, N; Bortolotto, ZA; Collingridge, GL; Davies, CH; Henley, JM; Irving, AJ; Jane, DE; Seal, AJ; Watkins, JC | 1 |
| Sahara, Y; Westbrook, GL | 1 |
| Averill, DB; Tsuchihashi, T | 1 |
| Behnisch, T; Reymann, KG | 1 |
| Fix, AS; Olney, JW; Price, MT; Romano, C; Tizzano, JP | 1 |
| Berrino, L; Leyva, J; Maione, S; Pallotta, M; Rossi, F | 1 |
| Cardoso, LF; Martini, LH; Souza, DO; Tasca, CI; Vendite, D | 1 |
| Fix, AS; Hall, RL; Horn, JW; Johnson, JA; Tizzano, JP | 1 |
| Maiese, K; Swiriduk, M; TenBroeke, M | 1 |
| Neuman, RS; Rahman, S | 1 |
| Nozaki-Taguchi, N; Yamamoto, T | 1 |
| Cai, Z; Rhodes, PG | 1 |
| Acosta-Burruel, M; Hawkinson, JE; Wood, PL | 1 |
| Kanfer, JN; Massarelli, R; Singh, IN; Sorrentino, G | 1 |
| Benz, AM; Izumi, Y; Kirby-Sharkey, CO; Labruyere, J; Mennerick, S; Olney, JW; Price, MT; Zorumski, CF | 1 |
| Goodnough, DB; Hawkinson, JE; Wood, PL | 1 |
| Challiss, RA; Godwin, M; Mistry, R; Prabhu, G | 1 |
| Fleischer-Lambropoulos, E; Geladopoulos, T; Kazazoglou, T; Kentroti, S; Stefanis, C; Vernadakis, A | 1 |
| Koerner, JF; Roon, RJ | 1 |
| Burke, JP; Hablitz, JJ | 1 |
| Fu, WM; Liou, HC; Yang, RS | 1 |
| Domenici, MR; Fortuna, S; Lorenzini, P; Michalek, H; Sagratella, S; Scotti de Carolis, A | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Evrard, P; Gressens, P; Marret, S | 1 |
| Gayton, RJ; Taylor, DC | 1 |
| Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y | 1 |
| Kagawa, Y; Mikoshiba, K; Yuzaki, M | 1 |
| Cossu, M; Fedele, E; Fontana, G; Munari, C; Raiteri, M | 1 |
| Kafarski, P; Krzyśko-Lupicka, T; Kubś, K; Lejczak, B; Skorupa, M; Strof, W; Wieczorek, P | 1 |
| Chase, TN; Nakai, M; Qin, ZH; Wang, Y | 1 |
| Birch, PJ; Blackburn-Munro, G; Bountra, C; Dickinson, T; Fleetwood-Walker, SM; Sparrow, H; Young, MR | 1 |
| Felipo, V; Hermenegildo, C; Llansola, M; Miñana, MD | 1 |
| Kitai, ST; Plenz, D | 1 |
| Magistretti, PJ; Martin, JL; Pellegri, G | 1 |
| Cross, AJ; Green, AR; Hewitt, KE; Misra, A; Snape, MF | 1 |
| Banno, T; Kohno, K | 1 |
| Nicoll, RA; Vogt, KE | 1 |
| Kato, BM; Rubel, EW | 1 |
| Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M | 1 |
| Ahmad, I; Gallant, J; Maiese, K; TenBroeke, M | 1 |
| Ahlemeyer, B; Hoffmann, GF; Kölker, S; Krieglstein, J | 1 |
| Darmani, NA; Pandya, DK | 1 |
| Luo, L; Qu, BQ; Sun, YL; Wang, TY; Xu, LX; Yuan, F | 1 |
| Foley, P; Matias, C; Quinta-Ferreira, ME | 1 |
| Randich, A; Turnbach, ME | 1 |
| Cho, JM; Heo, YS; Hwang, KY; Jeon, YH; Jeong, EJ; Kim, E; Kim, HY; Kim, JH; Kwon, D; Lee, TG; Moon, J; Park, MH; Park, SY; Ro, S; Shin, D; Yoon, J | 1 |
| Ding, JH; Hu, G; Li, H | 1 |
| Aránguez, I; Arce, C; Del Campo, AB; Figueroa, S; González, MP; López, E; Oset-Gasque, MJ | 1 |
| Awe, SO; Harris, LC; Kulkarni, K; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA | 1 |
| Blaabjerg, M; Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
| Bai, ZT; Chai, ZF; Ji, YH; Jiang, F; Liu, T; Pang, XY | 1 |
| Gilbert, JA; Kulakov, LA; Kulakova, AN; McGrath, JW; Quinn, JP; Villarreal-Chiu, JF | 1 |
| Chen, T; Li, X; Mercaldo, V; Shang, Y; Wang, H; Zhuo, M | 1 |
| Froeyen, M; Herdewijn, P; Lescrinier, E; Marlière, P; Yang, S | 1 |
| Feng, B; Gao, GD; Li, XQ; Liu, SB; Wu, YM; Xing, JH; Xu, ZH; Yang, Q; Zhang, N; Zhao, MG | 1 |
| Ceangă, M; Spataru, A; Zăgrean, AM; Zăgrean, L | 1 |
| Cui, D; Xu, J; Xu, Q; Zuo, G | 1 |
| Deng, Y; Li, X; Lin, X; Liu, B; Ma, J; Wang, S; Yuan, D | 1 |
| Ju, KS; Kayrouz, CM; Pham, TM; Zhang, Y | 1 |
126 other study(ies) available for alanine and 2-amino-3-phosphonopropionic acid
| Article | Year |
|---|---|
Evidence for metabotropic excitatory amino acid receptor heterogeneity: developmental and brain regional studies.
Topics: Aging; Alanine; Animals; Animals, Newborn; Brain; Cycloleucine; Drug Interactions; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tissue Distribution | 1992 |
Inhibition of the phospholipase C-linked metabotropic glutamate receptor by 2-amino-3-phosphonopropionate is dependent on extracellular calcium.
Topics: Alanine; Animals; Calcium; Chromatography, High Pressure Liquid; Cycloleucine; Extracellular Matrix; Glutamates; GTP-Binding Proteins; Hippocampus; Inositol 1,4,5-Trisphosphate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors; Type C Phospholipases | 1992 |
2-Amino-3-phosphonopropionate fails to block postsynaptic effects of metabotropic glutamate receptors in rat hippocampal neurones.
Topics: Action Potentials; Alanine; Animals; Cycloleucine; Female; Glutamates; Hippocampus; Male; Membrane Potentials; Neurons; Neurotoxins; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis.
Topics: Alanine; Allosteric Site; Animals; Asparagine; Biological Transport, Active; Drug Interactions; Hippocampus; Hydrolysis; Ibotenic Acid; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1992 |
Multiple metabotropic glutamate receptors regulate hippocampal function.
Topics: Alanine; Animals; Cycloleucine; Electric Stimulation; Electrophysiology; Hippocampus; Hydrolysis; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1992 |
Activation of metabotropic glutamate receptors in the hippocampus increases cyclic AMP accumulation.
Topics: Alanine; Animals; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Neurotoxins; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Metabotropic glutamate receptors are required for the induction of long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alanine; Aminobutyrates; Animals; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Male; Microinjections; Neurons; Organ Culture Techniques; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Time Factors | 1992 |
Characterization of a metabotropic glutamate receptor: direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alanine; Alkaloids; Animals; Cell Membrane; Cells, Cultured; Colforsin; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; In Vitro Techniques; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 1992 |
Long-term synaptic depression in the striatum: physiological and pharmacological characterization.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Bicuculline; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine Agents; Electric Stimulation; Electrophysiology; Male; Nerve Fibers; Neurons; Rats; Rats, Wistar; Scopolamine; Synapses; Time Factors | 1992 |
Neuroprotective synergism of 2-amino-3-phosphonoproprionate (D,L-AP3) and MK-801 against ibotenate induced brain injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Female; Ibotenic Acid; Injections; Male; Organ Size; Quinoxalines; Rats; Rats, Sprague-Dawley | 1992 |
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus | 1992 |
Evidence for a kynurenate-insensitive glutamate receptor in nucleus tractus solitarii.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Blood Pressure; Cycloleucine; Electric Stimulation; Female; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
L-2-amino-3-phosphonopropionate blocks late synaptic long-term potentiation.
Topics: Alanine; Animals; Hippocampus; In Vitro Techniques; Potentiometry; Rats; Synapses; Synaptic Transmission; Time Factors | 1991 |
Effects of ACPD and AP3 on parallel-fibre-mediated EPSPs of Purkinje cells in cerebellar slices in vitro.
Topics: Alanine; Animals; Calcium; Cerebellum; Cycloleucine; Evoked Potentials, Somatosensory; In Vitro Techniques; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
2-Amino-3-phosphonopropionate blocks the induction and maintenance of long-term potentiation in rat hippocampal slices.
Topics: Alanine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1991 |
2-Amino-3-phosphonopropionic acid, an inhibitor of glutamate-stimulated phosphoinositide turnover, blocks induction of homosynaptic long-term depression, but not potentiation, in rat hippocampus.
Topics: Alanine; Animals; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Synapses; Time Factors | 1991 |
Pharmacological characterization of the quisqualate receptor coupled to phospholipase C (Qp) in striatal neurons.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Cells, Cultured; Corpus Striatum; Dizocilpine Maleate; Fura-2; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Phorbol 12,13-Dibutyrate; Phosphoserine; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Type C Phospholipases | 1991 |
Roles of glutamate receptors in long-term potentiation at hippocampal mossy fiber synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Perfusion; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1991 |
Blockade of metabotropic glutamate receptors protects rat CA1 neurons from hypoxic injury.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Cell Hypoxia; Evoked Potentials; Glutamates; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Possible heterogeneity of metabotropic glutamate receptors induced in Xenopus oocytes by rat brain mRNA.
Topics: Alanine; Animals; Brain Chemistry; Cycloleucine; GTP-Binding Proteins; Ibotenic Acid; Oocytes; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1991 |
Pharmacological characterization of phosphoinositide-linked glutamate receptor excitation of hippocampal neurons.
Topics: Alanine; Animals; Cycloleucine; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Neurons; Pertussis Toxin; Phorbol Esters; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Virulence Factors, Bordetella | 1990 |
Autoradiographic imaging of phosphoinositide turnover in the brain.
Topics: Alanine; Animals; Autoradiography; Brain; Carbachol; Cerebellum; Cycloleucine; Cytidine; Cytidine Diphosphate Diglycerides; Glutamates; Glutamic Acid; Hippocampus; Neomycin; Phosphatidylinositols; Pirenzepine; Purkinje Cells; Rats; Receptors, Muscarinic; Tissue Distribution | 1990 |
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Brain; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Male; N-Methylaspartate; Pipecolic Acids; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism | 1990 |
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons.
Topics: Alanine; Animals; Calcium; Cerebellum; Cycloleucine; In Vitro Techniques; Neurons; Rats | 1990 |
Comparison of excitatory amino acid-stimulated phosphoinositide hydrolysis and N-[3H]acetylaspartylglutamate binding in rat brain: selective inhibition of phosphoinositide hydrolysis by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Carbachol; Dipeptides; Hippocampus; Hydrolysis; Ibotenic Acid; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Tritium | 1989 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the neonatal rat hippocampus by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Carbachol; Chlorides; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol; Kainic Acid; Kinetics; Lithium; Lithium Chloride; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Distribution of ciliatine (2-aminoethylphosphonic acid) and phosphonoalanine (2-amino-3-phosphonopropionic acid) in human tissues.
Topics: Adrenal Glands; Adult; Aged; Alanine; Aminoethylphosphonic Acid; Aorta; Brain Chemistry; Chromatography; Female; Humans; Intestines; Kidney; Liver; Male; Myocardium; Organophosphorus Compounds; Spleen; Tissue Distribution | 1989 |
[Effect of excitant amino acid antagonists on glutamate receptors in the locust and on convulsions induced by glutamate, aspartate, kynurenine and quinolinic acid in mice].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Glutamic Acid; Grasshoppers; Kynurenine; Male; Membrane Potentials; Mice; Muscles; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures | 1986 |
Utilization of the synthetic phosphagen cyclocreatine phosphate by a simple brain model during stimulation by neuroexcitatory amino acids.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chick Embryo; Glutamates; Glutamic Acid; Homocysteine; Imidazolidines; Kainic Acid; Magnesium; N-Methylaspartate; Phosphocreatine | 1988 |
Technetium-99m-labeled phosphonic acid analog of serine: bone uptake.
Topics: Alanine; Animals; Bone and Bones; Male; Mice; Organophosphorus Compounds; Propionates; Radionuclide Imaging; Technetium Tc 99m Medronate; Time Factors; Tissue Distribution | 1986 |
Phosphonate analogues of acidic amino acids: inhibition of excitatory amino acid transmitter binding to cerebellar membranes and of the stimulation of cerebellar cyclic GMP levels.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Aminobutyrates; Animals; Cerebellum; Cyclic GMP; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Neurotransmitter; Stereoisomerism; Valine | 1982 |
Metabolism of 2-amino-3-phosphono[3-14C]propionic acid in cell-free preparations of Tetrahymena.
Topics: Acetaldehyde; Alanine; Aminoethylphosphonic Acid; Animals; Cell-Free System; Organophosphorus Compounds; Pyruvates; Tetrahymena pyriformis | 1980 |
Activation of the metabotropic glutamate receptor is neuroprotective during nitric oxide toxicity in primary hippocampal neurons of rats.
Topics: Alanine; Animals; Animals, Newborn; Cell Survival; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
The effect of 2-amino-3-phosphonopropionic acid (AP-3) in the gerbil model of cerebral ischaemia.
Topics: Alanine; Animals; Brain Ischemia; Gerbillinae; Male; Motor Activity; Nerve Degeneration; Neurons; Receptors, Metabotropic Glutamate | 1995 |
Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dopamine; Electrophysiology; Female; Glycine; Male; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Tetrodotoxin | 1993 |
Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.
Topics: Acute Disease; Afferent Pathways; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Cycloleucine; Inflammation; Knee Joint; Male; N-Methylaspartate; Neurons; Pain; Pressure; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors.
Topics: Action Potentials; Adenosine; Alanine; Anesthetics; Animals; Anti-Anxiety Agents; Bicuculline; Corpus Striatum; Culture Techniques; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; GABA Antagonists; Hippocampus; Male; Muscimol; Neuronal Plasticity; Pregnanediones; Pregnanolone; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA; Receptors, Metabotropic Glutamate; Valine | 1995 |
L-2-amino-3-phosphonopropionic acid competitively antagonizes metabotropic glutamate receptors 1 alpha and 5 in Xenopus oocytes.
Topics: Alanine; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Evoked Potentials; Glutamic Acid; Oocytes; Receptors, Metabotropic Glutamate; Xenopus laevis | 1995 |
Astroglial phosphoinositide hydrolysis during combined glucose-oxygen deprivation: role of the metabotropic glutamate receptor.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Benzoates; Cells, Cultured; Glucose; Glutamic Acid; Glycine; Hydrolysis; Inositol Phosphates; L-Lactate Dehydrogenase; Lithium Chloride; Oxygen; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tritium | 1995 |
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo(F)-quinoxaline (NBQX).
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Pertussis Toxin; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Virulence Factors, Bordetella | 1993 |
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Two components in neurotoxicity by L-2-amino-3-phosphonopropionate in cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Neurons; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Effect of activity at metabotropic, as well as ionotropic (NMDA), glutamate receptors on morphine dependence.
Topics: Alanine; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzoates; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Morphine Dependence; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1994 |
Activation of Ca2+/calmodulin-dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Animals, Newborn; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Immunoblotting; Ionomycin; Molecular Weight; Phosphoproteins; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Vimentin | 1994 |
Rapid desensitization of the metabotropic glutamate receptor that facilitates glutamate release in rat cerebrocortical nerve terminals.
Topics: Alanine; Aminobutyrates; Animals; Cerebral Cortex; Diglycerides; Exocytosis; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Nerve Endings; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission; Synaptosomes; Virulence Factors, Bordetella | 1994 |
Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice.
Topics: Alanine; Aminobutyrates; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Fluid; Mice; omega-Conotoxin GVIA; Organophosphorus Compounds; Peptides; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells | 1994 |
Stimulation of postsynaptic and inhibition of presynaptic adenylyl cyclase activity by metabotropic glutamate receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Enzyme Activation; Glutamates; Glutamic Acid; Male; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses; Synaptosomes | 1994 |
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated.
Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
Activation of metabotropic glutamate receptors inhibits calcium currents and GABA-mediated synaptic potentials in striatal neurons.
Topics: Alanine; Animals; Calcium; Corpus Striatum; Cycloleucine; Electrophysiology; gamma-Aminobutyric Acid; Male; Neurons; Neurotoxins; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1994 |
Modulation of GABA-mediated synaptic transmission by endogenous zinc in the immature rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Alanine; Animals; Animals, Newborn; Bicuculline; Cations, Divalent; Chelating Agents; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Histidine; In Vitro Techniques; Iron Chelating Agents; Pyramidal Tracts; Pyridones; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Zinc | 1994 |
Metabotropic glutamate receptors are involved in the control of breathing at the medulla oblongata level of anaesthetized rats.
Topics: Alanine; Anesthesia; Animals; Blood Pressure; Cycloleucine; Glutamic Acid; Injections; Male; Medulla Oblongata; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Respiratory Mechanics; Solitary Nucleus | 1994 |
Metabotropic glutamate receptors modulate N-methyl-D-aspartate receptor function in neostriatal neurons.
Topics: Action Potentials; Alanine; Animals; Cycloleucine; Iontophoresis; Male; Microelectrodes; N-Methylaspartate; Neostriatum; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Developmental changes in the effects of metabotropic glutamate receptor antagonists on CA1 long-term potentiation in rat hippocampal slices.
Topics: Aging; Alanine; Aminobutyrates; Animals; Benzoates; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Pyramidal Cells; Rats; Receptors, Metabotropic Glutamate | 1994 |
Release of [3H]GABA evoked by glutamate agonists from hippocampal slices: effects of dithiothreitol and glutathione.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dithiothreitol; Dizocilpine Maleate; GABA Agonists; gamma-Aminobutyric Acid; Glutathione; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Magnesium; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tritium | 1994 |
Pharmacology of metabotropic glutamate receptor inhibition of cyclic AMP formation in the adult rat hippocampus.
Topics: Alanine; Animals; Colforsin; Cyclic AMP; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Pharmacological characterization of metabotropic glutamate receptors in cultured cerebellar granule cells.
Topics: Alanine; Amino Acids, Diamino; Animals; Cells, Cultured; Cerebellum; Cyanobacteria Toxins; Cycloleucine; Drug Interactions; Enzyme Activation; Glutamates; Glutamic Acid; Ibotenic Acid; Magnesium; N-Methylaspartate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Quisqualic Acid; Rats; Receptors, Glutamate | 1993 |
Purkinje cell survival is differentially regulated by metabotropic and ionotropic excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Cell Survival; Cells, Cultured; Cyclopentanes; Dizocilpine Maleate; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Modulation by metabotropic glutamate receptor of long-term potentiation of population spikes in the dentate gyrus in vivo.
Topics: Action Potentials; Alanine; Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Male; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Time Factors | 1994 |
Reduction of phosphoinositide hydrolysis by L-amino-3-phosphonopropionate may be caused by the inhibition of synthesis of phosphatidylinositols.
Topics: Alanine; Animals; Atropine; Carbachol; Cycloleucine; Depression, Chemical; Hippocampus; Hydrolysis; In Vitro Techniques; Inositol; Lithium Chloride; Male; Phosphatidylinositols; Rats; Rats, Wistar | 1993 |
Neonatal exposure to D,L-2-amino-3-phosphonopropionate (D,L-AP3) produces lesions in the eye and optic nerve of adult rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Eye; Eye Diseases; Male; Optic Nerve; Optic Nerve Diseases; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Retinal Diseases | 1993 |
Heterogeneity of metabotropic glutamate receptors in the striatum: electrophysiological evidence.
Topics: Alanine; Aminobutyrates; Animals; Cerebral Cortex; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Lithium Chloride; Neuronal Plasticity; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synapses | 1993 |
Functional evidence for a L-AP3-sensitive metabotropic receptor different from glutamate metabotropic receptor mGluR1.
Topics: Alanine; Animals; Cells, Cultured; Cerebellum; Culture Media; Cycloleucine; Granulocytes; Inositol Phosphates; Neurons; Osmolar Concentration; Potassium Chloride; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; RNA, Messenger | 1993 |
(1S, 3R)-ACPD protects synaptic transmission from hypoxia in hippocampal slices.
Topics: Alanine; Animals; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 1993 |
Coactivation of metabotropic and NMDA receptors is required for LTP induction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Animals; Carbachol; Cyclic AMP; Cycloleucine; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Thionucleotides | 1993 |
L-AP3 does not antagonize hippocampal synaptic depression induced by 1S,3R-ACPD.
Topics: Alanine; Animals; Cycloleucine; Dendrites; Evoked Potentials; Extracellular Space; Hippocampus; In Vitro Techniques; Phosphatidylinositols; Rats; Rats, Wistar; Synapses | 1993 |
Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors.
Topics: Action Potentials; Alanine; Animals; Benzoates; CHO Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons.
Topics: Alanine; Animals; Animals, Newborn; Barium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Kinetics; Membrane Potentials; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tetrodotoxin; Time Factors; Virulence Factors, Bordetella | 1993 |
Metabotropic glutamate receptors in the ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Blood Pressure; Cycloleucine; Dose-Response Relationship, Drug; Drug Combinations; Male; Medulla Oblongata; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical | 1993 |
Co-activation of metabotropic glutamate and N-methyl-D-aspartate receptors is involved in mechanisms of long-term potentiation maintenance in rat hippocampal CA1 neurons.
Topics: Alanine; Animals; Cycloleucine; Electrophysiology; Hippocampus; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents.
Topics: Alanine; Animals; Animals, Newborn; Asparagine; Brain Diseases; Excitatory Amino Acid Antagonists; Isomerism; Mice; Mice, Inbred ICR; Nerve Degeneration; Optic Nerve; Phosphoserine; Rats; Receptors, Metabotropic Glutamate; Retinal Degeneration; Second Messenger Systems | 1995 |
Metabotropic and ionotropic glutamate receptors mediate opposite effects on periaqueductal gray matter.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Blood Pressure; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Neurons; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Modulation of adenosine-induced cAMP accumulation via metabotropic glutamate receptors in chick optic tectum.
Topics: Adenosine; Alanine; Animals; Benzoates; Chickens; Cyclic AMP; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Male; Quinoxalines; Receptors, Metabotropic Glutamate; Superior Colliculi | 1995 |
Progressive retinal toxicity in neonatal rats treated with D,L-2-amino-3-phosphonopropionate (D,L-AP3).
Topics: Alanine; Animals; Animals, Newborn; Cytoplasm; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Microscopy, Electron; Necrosis; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Retina; Stereoisomerism; Synaptic Transmission | 1995 |
Glutamate-independent long term depression in rat hippocampus by activation GABAA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Alanine; Animals; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Kynurenic Acid; Male; Muscimol; Neuronal Plasticity; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A | 1996 |
Cellular mechanisms of protection by metabotropic glutamate receptors during anoxia and nitric oxide toxicity.
Topics: Alanine; Aminobutyrates; Animals; Brain Ischemia; Cell Death; Cell Hypoxia; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction | 1996 |
Characterization of metabotropic glutamate receptor-mediated facilitation of N-methyl-D-aspartate depolarization of neocortical neurones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Alkaloids; Aminobutyrates; Animals; Cerebral Cortex; Cyclic GMP; Cycloleucine; Male; Neurons; Phorbol Esters; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Staurosporine | 1996 |
Zinc protoporphyrin IX, an inhibitor of the enzyme that produces carbon monoxide, blocks spinal nociceptive transmission evoked by formalin injection in the rat.
Topics: Alanine; Animals; Behavior, Animal; Benzoates; Carbon Monoxide; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Heme Oxygenase (Decyclizing); Hot Temperature; Injections, Spinal; Male; Nociceptors; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptic Transmission | 1995 |
Intrauterine hypoxia-ischemia reduces phosphoinositide hydrolysis stimulated by metabotropic glutamate receptor agonists in cultured rat cerebellar granule cells.
Topics: Alanine; Animals; Brain Ischemia; Cell Count; Cells, Cultured; Cerebellum; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fetal Hypoxia; Hydrolysis; Hypoxia, Brain; Neurons; Neurotoxins; omega-N-Methylarginine; Phosphatidylinositols; Pregnancy; Proteins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1996 |
The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase.
Topics: Alanine; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Phosphoric Monoester Hydrolases; Rats; Receptors, Metabotropic Glutamate; Serine; Stereoisomerism | 1996 |
Stimulation of phospholipase C activity by norepinephrine, t-ACPD and bombesin in LA-N-2 cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alanine; Bombesin; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Humans; Inositol Phosphates; Isoproterenol; Isotope Labeling; Neuroblastoma; Neurokinin B; Neurotoxins; Norepinephrine; Propranolol; Receptors, Bombesin; Receptors, Metabotropic Glutamate; Tritium; Tumor Cells, Cultured; Type C Phospholipases | 1996 |
Swelling of Müller cells induced by AP3 and glutamate transport substrates in rat retina.
Topics: Alanine; Animals; Biological Transport; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Ligands; Neuroglia; Rats; Receptors, Metabotropic Glutamate; Retina; Sodium; Substrate Specificity | 1996 |
Formation of D-serine from L-phosphoserine in brain synaptosomes.
Topics: Alanine; Animals; Biological Transport; Cerebral Cortex; Excitatory Amino Acid Antagonists; Hydrolysis; Kinetics; Male; Phosphoric Monoester Hydrolases; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine; Stereoisomerism; Synaptosomes | 1996 |
Stimulatory effects of the putative metabotropic glutamate receptor antagonist L-AP3 on phosphoinositide turnover in neonatal rat cerebral cortex.
Topics: Alanine; Animals; Animals, Newborn; Cerebral Cortex; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Inositol Phosphates; Male; Mice; Neurotoxins; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereoisomerism | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
Persistent depression of synaptic responses occurs in quisqualate sensitized hippocampal slices after exposure to L-aspartate-beta-hydroxamate.
Topics: 2-Aminoadipic Acid; Action Potentials; Alanine; Animals; Asparagine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hippocampus; Hydroxamic Acids; In Vitro Techniques; Male; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Potentiation of spontaneous acetylcholine release from motor nerve terminals by glutamate in Xenopus tadpoles.
Topics: Acetylcholine; Alanine; Animals; Calcium; Calcium Channel Blockers; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Larva; Motor Endplate; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Second Messenger Systems; Verapamil; Xenopus laevis | 1996 |
Glutamate-dependent mechanisms in the induction of a calcium long-term potentiation-like phenomenon.
Topics: Alanine; Animals; Brain Chemistry; Calcium; Cyclazocine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Narcotic Antagonists; Pipecolic Acids; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Arrest of neuronal migration by excitatory amino acids in hamster developing brain.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Animals, Newborn; Brain; Cell Differentiation; Cell Division; Cell Movement; Cricetinae; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Matrix; Female; Humans; Ibotenic Acid; Male; Mesocricetus; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate | 1996 |
The effect of metabotropic excitatory amino-acid receptor agonists and antagonists on hypothalamic neurons which respond to changes in scrotal skin temperature in the anesthetized male rat.
Topics: Action Potentials; Alanine; Animals; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hot Temperature; Hypothalamus, Anterior; Male; Neurons; Preoptic Area; Rats; Scrotum; Thermoreceptors | 1997 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Characterization of metabotropic glutamate receptors in cultured Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Ibotenic Acid; Kinetics; Membrane Potentials; Purkinje Cells; Receptors, Metabotropic Glutamate; Time Factors; Virulence Factors, Bordetella | 1993 |
Activation of brain nitric oxide synthase in depolarized human temporal cortex slices: differential role of voltage-sensitive calcium channels.
Topics: Alanine; Arginine; Calcium Channel Blockers; Calcium Channels; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mecamylamine; Nicotinic Antagonists; Nitric Oxide Synthase; Nitroarginine; Potassium; Potassium Chloride; Quinoxalines; Temporal Lobe | 1997 |
The ability of soil-borne fungi to degrade organophosphonate carbon-to-phosphorus bonds.
Topics: Alanine; Aminoethylphosphonic Acid; Aspergillus niger; Bacteria, Aerobic; Bacteria, Anaerobic; Biodegradation, Environmental; Carbon; Environmental Pollutants; Fungi; Glycine; Glyphosate; Organophosphorus Compounds; Phosphonoacetic Acid; Phosphorus; Soil Microbiology; Species Specificity; Trichoderma | 1997 |
Glutamate metabotropic receptor agonist 1S,3R-ACPD induces internucleosomal DNA fragmentation and cell death in rat striatum.
Topics: Alanine; Animals; Autoradiography; Cell Death; Cycloleucine; DNA Fragmentation; Electrophoresis, Agar Gel; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Neurotoxins; Nucleosomes; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1997 |
Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord.
Topics: Alanine; Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glycine; Male; Mustard Plant; Neuroprotective Agents; Nociceptors; Pain; Phenylacetates; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Carbachol-induced hydrolysis of phospholipids in hippocampal slices may be mediated in part by subsequent activation of metabotropic glutamate receptors.
Topics: Alanine; Animals; Aspartic Acid; Carbachol; Cerebellum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Hydrolysis; In Vitro Techniques; Male; Muscarinic Agonists; Neurons; Phospholipids; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Type C Phospholipases | 1998 |
Regulation of the nigrostriatal pathway by metabotropic glutamate receptors during development.
Topics: Alanine; Animals; Cerebral Cortex; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Microscopy, Confocal; Nerve Fibers; Neural Pathways; Neurons; Neuroprotective Agents; Organ Culture Techniques; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Second Messenger Systems; Substantia Nigra; Tyrosine 3-Monooxygenase | 1998 |
VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Mice; Neuronal Plasticity; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Vasoactive Intestinal Peptide | 1998 |
An investigation of the possible interaction of clomethiazole with glutamate and ion channel sites as an explanation of its neuroprotective activity.
Topics: Alanine; Animals; Chlormethiazole; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Ion Channels; Male; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Rats; Receptors, Glutamate | 1998 |
Conformational changes of the smooth endoplasmic reticulum are facilitated by L-glutamate and its receptors in rat Purkinje cells.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apnea; Bradycardia; Calcium Signaling; Cycloleucine; Dendrites; Endoplasmic Reticulum, Smooth; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia, Brain; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration | 1998 |
Glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Morpholines; Nerve Fibers; Organophosphorus Compounds; Pyramidal Cells; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synapses | 1999 |
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides | 1999 |
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; Catheters, Indwelling; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Locomotion; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Synaptic Transmission; Valine | 1999 |
Metabotropic glutamate receptor subtypes independently modulate neuronal intracellular calcium.
Topics: Alanine; Analysis of Variance; Animals; Calcium; Cells, Cultured; Cyclopropanes; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indans; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction | 1999 |
Methylmalonic acid induces excitotoxic neuronal damage in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Survival; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Methylmalonic Acid; Neurons; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Piperidines | 2000 |
Involvement of other neurotransmitters in behaviors induced by the cannabinoid CB1 receptor antagonist SR 141716A in naive mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Head Movements; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Phenols; Piperidines; Psychotropic Drugs; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Serotonin Antagonists; Tachykinins | 2000 |
Neurotoxic effect of high dose of L-(+)-2-amino-3-phosphonopropionic acid in rats after intracaudatal injection.
Topics: Alanine; Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Calcium; Caudate Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Rats; Rats, Wistar | 2001 |
L-AP3 blocks rises in intracellular calcium associated with hippocampal CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Calcium; Calcium Signaling; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; Hippocampus; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Long-Term Potentiation; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 2002 |
The role of spinal neurokinin-1 and glutamate receptors in hyperalgesia and allodynia induced by prostaglandin E(2) or zymosan in the rat.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Dinoprostone; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Zymosan | 2002 |
Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
Topics: Alanine; Binding Sites; Enzyme Inhibitors; Humans; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Protein Conformation; Serine; Substrate Specificity | 2002 |
Group I mGluR ligands fail to affect 6-hydroxydopamine- induced death and glutamate release of PC12 cells.
Topics: Adrenergic Agents; Alanine; Animals; Apoptosis; Cell Survival; DNA Fragmentation; Drug Interactions; Glutamic Acid; Ligands; Methoxyhydroxyphenylglycol; Oxidopamine; PC12 Cells; Rats; Receptors, Metabotropic Glutamate | 2003 |
Expression and functional properties of group I metabotropic glutamate receptors in bovine chromaffin cells.
Topics: Adrenal Medulla; Alanine; Animals; Calcium; Calcium Channels; Calcium Signaling; Cattle; Cells, Cultured; Chromaffin Cells; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Methoxyhydroxyphenylglycol; Nicotine; Norepinephrine; Reaction Time; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Nicotinic | 2004 |
Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
Topics: Alanine; Animals; Biguanides; Calcium Channel Blockers; Cattle; D-Aspartic Acid; Diltiazem; Dizocilpine Maleate; Drug Synergism; Glucose; Glutamic Acid; Glycine; Humans; Kainic Acid; N-Methylaspartate; Nitrendipine; omega-Conotoxins; Perfusion; Piperidines; Polyamines; Receptors, Glutamate; Retina; Tritium; Verapamil | 2003 |
Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation.
Topics: Alanine; Animal Testing Alternatives; Animals; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; L-Lactate Dehydrogenase; Propidium; Quinoxalines; Rats; Staining and Labeling; Tissue Culture Techniques | 2007 |
Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Pain; Proline; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scorpion Venoms | 2007 |
Expression of the phosphonoalanine-degradative gene cluster from Variovorax sp. Pal2 is induced by growth on phosphonoalanine and phosphonopyruvate.
Topics: Alanine; Artificial Gene Fusion; Comamonadaceae; DNA, Bacterial; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Order; Genes, Reporter; Green Fluorescent Proteins; Molecular Sequence Data; Multigene Family; Pyruvates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology | 2009 |
Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Analysis of Variance; Animals; Biophysics; Bromodeoxyuridine; Butadienes; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; GABA Antagonists; Gene Expression Regulation; Glycine; Glycine Agents; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Nitriles; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells | 2009 |
3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.
Topics: Alanine; Biomimetic Materials; DNA; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Molecular Structure; Organophosphonates; Phosphoric Acids | 2011 |
Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome.
Topics: Alanine; Animals; Cells, Cultured; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Knockout; Neurons; Receptors, AMPA; Receptors, Metabotropic Glutamate | 2012 |
The single versus combinatorial effects of MK-801, CNQX, Nifedipine and AP-3 on primary cultures of cerebellar granule cells in an oxygen-glucose deprivation model.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cell Death; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Drug Therapy, Combination; Fluorescence; Glucose; Nifedipine; Oxygen; Propidium; Rats | 2014 |
DL-2-amino-3-phosphonopropionic acid protects primary neurons from oxygen-glucose deprivation induced injury.
Topics: Alanine; Animals; Apoptosis; Brain Infarction; Cell Survival; Cells, Cultured; Cytochromes c; Down-Regulation; Female; Flow Cytometry; Glucose; Neurons; Neuroprotective Agents; Oxygen; Primary Cell Culture; Rats; Rats, Sprague-Dawley | 2017 |
High-performance liquid chromatographic determination of 2-aminoethylphosphonic acid and 2-amino-3-phosphonopropionic acid in seawater matrix using precolumn fluorescence derivatization with o-phthalaldehyde-ethanethiol.
Topics: Alanine; Aminoethylphosphonic Acid; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Seawater; Spectrometry, Fluorescence; Sulfhydryl Compounds | 2018 |
Genome Mining Reveals the Phosphonoalamide Natural Products and a New Route in Phosphonic Acid Biosynthesis.
Topics: Alanine; Anti-Bacterial Agents; Bacteria; Genome, Bacterial; Genomics; Microbial Sensitivity Tests; Multigene Family; Organophosphonates; Peptides; Pyruvates | 2020 |