alanine has been researched along with 11-cis-retinal in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franke, RR; Khorana, HG; Lin, SW; Mathies, RA; Sakmar, TP | 1 |
| Greenhalgh, DA; Khorana, HG; Rath, P; Rothschild, KJ; Subramaniam, S | 1 |
| Mandel, P; Trayhurn, P; Virmaux, N | 1 |
| Hennessey, JC; Macke, JP; Nathans, J | 1 |
| Dickerson, CD; Osawa, S; Shi, W; Weiss, ER | 1 |
| Davidson, FF; Khorana, HG; Loewen, PC | 1 |
| Cerione, RA; Erickson, JW; Mittal, R | 1 |
| Han, M; Lin, SW; Minkova, M; Sakmar, TP; Smith, SO | 1 |
| Osawa, S; Sports, CD; Weiss, ER; Zhang, L | 1 |
| Beck, M; Sakmar, TP; Siebert, F | 1 |
| Farrens, DL; Janz, JM | 1 |
| Krishna, AG; Marin, EP; Sakmar, TP | 1 |
| Adolfsen, W; Caldwell, CG; Castonguay, LA; Daugherty, BL; DeMartino, JA; Di Salvo, J; Finke, PE; Hale, JJ; Kilburn, R; Lynch, CL; MacCoss, M; Mills, SG; Springer, MS; Weng, Y | 1 |
| Gross, AK; Oprian, DD; Xie, G | 1 |
| Claeysen, S; Costagliola, S; Deupí, X; Govaerts, C; Pardo, L; Urizar, E; Vassart, G | 1 |
| Downs, MA; Kisselev, OG | 1 |
| Crozier, PS; Stevens, MJ; Woolf, TB | 1 |
| Kandori, H; Kawanabe, A; Yamada, K | 1 |
| Gonzalez, J; Jaeschke, H; Kleinau, G; Krause, G; Mueller, S; Paschke, R; Worth, CL | 1 |
| Ahuja, S; Eilers, M; Goncalves, JA; Opefi, CA; Reeves, PJ; Smith, SO; South, K; Vogel, R; Zaitseva, E | 1 |
| Cordomi, A; Garriga, P; Martinez-Archundia, M; Perez, JJ | 1 |
| Bertranpetit, J; Fernández-Sampedro, MA; Garriga, P; Invergo, BM; Ramon, E | 1 |
| Baksheeva, VE; Denessiouk, K; Denesyuk, AI; Kazakov, AS; Nemashkalova, EL; Permyakov, EA; Permyakov, SE; Uversky, VN; Vologzhannikova, AS; Zamyatnin, AA; Zernii, EY | 1 |
23 other study(ies) available for alanine and 11-cis-retinal
| Article | Year |
|---|---|
Resonance Raman microprobe spectroscopy of rhodopsin mutants: effect of substitutions in the third transmembrane helix.
Topics: Alanine; Animals; Binding Sites; Cattle; Glutamates; Glutamic Acid; Glutamine; Isomerism; Models, Molecular; Molecular Conformation; Mutation; Rhodopsin; Spectrum Analysis, Raman | 1992 |
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization.
Topics: Alanine; Amino Acid Sequence; Bacteriorhodopsins; Cloning, Molecular; Darkness; Escherichia coli; Isomerism; Kinetics; Leucine; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protons; Recombinant Proteins; Retinaldehyde; Rhodopsin; Spectrophotometry; Threonine | 1991 |
Composition of the rhodopsin-core obtained by proteolysis of retinal rod outer segments with papain, and its regenerability after photobleaching.
Topics: Alanine; Animals; Arginine; Carbohydrates; Cattle; Chromatography, Thin Layer; Electrophoresis; Glutamates; Glycine; Histidine; Leucine; Light; Lysine; Papain; Photoreceptor Cells; Retinal Pigments; Retinaldehyde; Rhodopsin; Threonine; Tryptophan; Tyrosine | 1974 |
Rhodopsin mutation proline347-to-alanine in a family with autosomal dominant retinitis pigmentosa indicates an important role for proline at position 347.
Topics: Alanine; Amino Acid Sequence; Base Sequence; DNA; Female; Genes, Dominant; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Proline; Retinitis Pigmentosa; Rhodopsin | 1995 |
Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Enzyme Activation; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Rhodopsin; Structure-Activity Relationship; Transducin | 1995 |
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Cysteine; Disulfides; Guanine Nucleotides; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Recombinant Proteins; Rhodopsin; Rod Opsins; Structure-Activity Relationship; Temperature; Transducin | 1994 |
Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Alanine; Animals; Base Sequence; Cattle; Enzyme Activation; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Rhodopsin; Transducin | 1996 |
Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Phenylalanine; Rhodopsin; Rod Opsins; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Transducin | 1996 |
Rhodopsin phosphorylation sites and their role in arrestin binding.
Topics: Alanine; Amino Acid Sequence; Animals; Arrestin; Binding Sites; Cattle; Cell Line; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Humans; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Secondary; Recombinant Proteins; Rhodopsin; Serine; Threonine; Transfection | 1997 |
Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Cattle; Glutamic Acid; Glutamine; Histidine; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Protein Structure, Secondary; Rhodopsin; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transducin | 1998 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Gene Deletion; Molecular Sequence Data; Mutagenesis; Mutagenesis, Insertional; Nucleotides; Proline; Protein Structure, Secondary; Rhodopsin; Transducin | 2002 |
Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: a molecular modeling-guided mutagenesis study of the binding pocket.
Topics: Alanine; Amides; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Butanes; Cattle; CCR5 Receptor Antagonists; CHO Cells; Cricetinae; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperidines; Protein Structure, Secondary; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, CCR5; Rhodopsin; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2003 |
Slow binding of retinal to rhodopsin mutants G90D and T94D.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; Glutamine; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Insertional; Night Blindness; Protein Binding; Protein Denaturation; Retinaldehyde; Rhodopsin; Schiff Bases; Spectrophotometry, Ultraviolet; Threonine | 2003 |
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
Topics: Alanine; Amino Acid Motifs; Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Cell Membrane; Cell Separation; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Flow Cytometry; Hydrogen Bonding; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Thyrotropin; Rhodopsin; Software; Static Electricity; Threonine; Transfection | 2005 |
Rhodopsin-interacting surface of the transducin gamma subunit.
Topics: Alanine; Amino Acid Sequence; Animals; Cattle; Conserved Sequence; DNA Mutational Analysis; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Interaction Mapping; Protein Structure, Tertiary; Rhodopsin; Transducin | 2006 |
How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.
Topics: Alanine; Animals; Binding Sites; Cattle; Computer Simulation; GTP-Binding Proteins; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Retinaldehyde; Rhodopsin; X-Ray Diffraction | 2007 |
Importance of alanine at position 178 in proteorhodopsin for absorption of prevalent ambient light in the marine environment.
Topics: Absorption; Alanine; Hydrogen-Ion Concentration; Light; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oceans and Seas; Protein Conformation; Rhodopsin; Rhodopsins, Microbial; Seawater; Spectrophotometry, Ultraviolet | 2010 |
Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.
Topics: Alanine; Animals; Catalytic Domain; Cell Separation; Chlorocebus aethiops; Computational Biology; COS Cells; Cyclic AMP; Humans; Inositol Phosphates; Models, Molecular; Mutation; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Rhodopsin; Thyrotropin | 2010 |
Highly conserved tyrosine stabilizes the active state of rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Conserved Sequence; Crystallography, X-Ray; HEK293 Cells; Humans; Ion Channel Gating; Magnetic Resonance Spectroscopy; Mutant Proteins; Mutation; Protein Conformation; Protein Stability; Protein Structure, Secondary; Rhodopsin; Signal Transduction; Structure-Activity Relationship; Tyrosine | 2010 |
Molecular modeling of the M3 acetylcholine muscarinic receptor and its binding site.
Topics: Alanine; Animals; Binding Sites; Cattle; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Protein Binding; Receptor, Muscarinic M3; Rhodopsin | 2012 |
Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution.
Topics: Adaptation, Physiological; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Biological Evolution; Chlorocebus aethiops; COS Cells; G-Protein-Coupled Receptor Kinase 1; Gene Expression; Glutamine; Glycosylation; Humans; Mammals; Methionine; Models, Molecular; Mutation; Phenylalanine; Phosphorylation; Phylogeny; Protein Folding; Recombinant Proteins; Rhodopsin; Selection, Genetic; Serine | 2016 |
Experimental Insight into the Structural and Functional Roles of the 'Black' and 'Gray' Clusters in Recoverin, a Calcium Binding Protein with Four EF-Hand Motifs.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Calcium; G-Protein-Coupled Receptor Kinase 1; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Mutation; Phosphorylation; Protein Binding; Recoverin; Rhodopsin | 2019 |