alamethicin and 6-carboxyfluorescein

alamethicin has been researched along with 6-carboxyfluorescein* in 1 studies

Other Studies

1 other study(ies) available for alamethicin and 6-carboxyfluorescein

Article	Year
The lipid dependence of antimicrobial peptide activity is an unreliable experimental test for different pore models. Biochemistry, 2012, Dec-21, Volume: 51, Issue:51 Antimicrobial peptides usually kill bacteria by making their membranes permeable. Two main models (barrel-stave and Shai-Matsuzaki-Huang) have been proposed to describe the peptide-induced pores. Although several experimental tests can be exploited to discriminate between these two models, the dependence of peptide activity on lipid properties (intrinsic curvature and membrane thickness) is routinely used for this purpose. Here, we show that, contrary to what is currently accepted, this criterion is unreliable. Topics: Alamethicin; Anti-Infective Agents; Antimicrobial Cationic Peptides; Fluoresceins; Intercellular Signaling Peptides and Proteins; Lipid Bilayers; Liposomes; Membranes; Models, Theoretical; Peptides	2012

Article

Year

The lipid dependence of antimicrobial peptide activity is an unreliable experimental test for different pore models.

Biochemistry, 2012, Dec-21, Volume: 51, Issue:51

Antimicrobial peptides usually kill bacteria by making their membranes permeable. Two main models (barrel-stave and Shai-Matsuzaki-Huang) have been proposed to describe the peptide-induced pores. Although several experimental tests can be exploited to discriminate between these two models, the dependence of peptide activity on lipid properties (intrinsic curvature and membrane thickness) is routinely used for this purpose. Here, we show that, contrary to what is currently accepted, this criterion is unreliable.

Topics: Alamethicin; Anti-Infective Agents; Antimicrobial Cationic Peptides; Fluoresceins; Intercellular Signaling Peptides and Proteins; Lipid Bilayers; Liposomes; Membranes; Models, Theoretical; Peptides

2012