alagebrium has been researched along with pyruvaldehyde in 5 studies
*Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [MeSH]
*Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [MeSH]
| Studies (alagebrium) | Trials (alagebrium) | Recent Studies (post-2010) (alagebrium) | Studies (pyruvaldehyde) | Trials (pyruvaldehyde) | Recent Studies (post-2010) (pyruvaldehyde) |
|---|---|---|---|---|---|
| 83 | 10 | 31 | 2,458 | 34 | 1,447 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Desai, KM; Dhar, A; Wu, L | 1 |
| Desai, KM; Dhar, A; Dhar, I; Wu, L | 1 |
| Bhat, A; Desai, KM; Dhar, A; Dhar, I | 1 |
| Babu, MS; Bhat, A; Desai, KM; Dhar, A; Dhar, I; Kalra, J; Malapati, P; Medapi, B; Sriram, D; Udumula, MP | 1 |
5 other study(ies) available for alagebrium and pyruvaldehyde
| Article | Year |
|---|---|
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Male; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrosine | 2010 |
Methylglyoxal, a reactive glucose metabolite, increases renin angiotensin aldosterone and blood pressure in male Sprague-Dawley rats.
Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholamines; Cells, Cultured; Disease Models, Animal; Hypertension; Male; NF-kappa B; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Signal Transduction; Thiazoles; Time Factors; Up-Regulation | 2014 |
Alagebrium attenuates methylglyoxal induced oxidative stress and AGE formation in H9C2 cardiac myocytes.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cells, Cultured; Free Radical Scavengers; Glucose; Glycation End Products, Advanced; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Rats; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Thiazoles | 2016 |
Pharmacological evaluation of novel alagebrium analogs as methylglyoxal scavengers in vitro in cardiac myocytes and in vivo in SD rats.
Topics: Animals; Cells, Cultured; Drug Evaluation, Preclinical; Glycation End Products, Advanced; Male; Myocytes, Cardiac; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiazoles | 2016 |