al 4114 has been researched along with hydantoins in 4 studies
| Studies (al 4114) | Trials (al 4114) | Recent Studies (post-2010) (al 4114) | Studies (hydantoins) | Trials (hydantoins) | Recent Studies (post-2010) (hydantoins) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 3,404 | 80 | 435 |
| Protein | Taxonomy | al 4114 (IC50) | hydantoins (IC50) |
|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.062 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burgan, JH; Nyengaard, JR; Ostrow, E; Van den Enden, MK; Williamson, JR | 1 |
| Sanders, RA; Sastry, SG; Veltman, JC; Watkins, JB | 1 |
| Lou, MF; Xu, GT; York, B; Zigler, S | 1 |
| Rauscher, F; Sanders, R; Thomas, T; Veltman, J; Watkins, JB | 1 |
4 other study(ies) available for al 4114 and hydantoins
| Article | Year |
|---|---|
Elevated glucose levels increase retinal glycolysis and sorbitol pathway metabolism. Implications for diabetic retinopathy.
Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Fluorenes; Fructose; Glucose; Glycolysis; Hydantoins; Inositol; Lactates; Male; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Spiro Compounds | 1995 |
Minimal effects of two aldose reductase inhibitors, AL-1576 and AL-4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits.
Topics: Administration, Topical; Aldehyde Reductase; Animals; Biotransformation; Enzyme Inhibitors; Eye; Fluorenes; Hydantoins; Kidney; Liver; Rabbits; Spiro Compounds; Xenobiotics | 1995 |
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds | 1996 |
Effects of aldose reductase inhibitors on antioxidant defense in rat and rabbit liver.
Topics: Aldehyde Reductase; Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorenes; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hydantoins; Lipid Peroxidation; Liver; Male; Oxidative Stress; Oxidoreductases; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Spiro Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2000 |