al-01567 has been researched along with ponalrestat in 2 studies
| Studies (al-01567) | Trials (al-01567) | Recent Studies (post-2010) (al-01567) | Studies (ponalrestat) | Trials (ponalrestat) | Recent Studies (post-2010) (ponalrestat) |
|---|---|---|---|---|---|
| 13 | 0 | 2 | 165 | 23 | 12 |
| Protein | Taxonomy | al-01567 (IC50) | ponalrestat (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.616 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.048 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 0.022 | |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | 2 | |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | 0.021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beyer, TA; Mylari, BL; Siegel, TW | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
1 review(s) available for al-01567 and ponalrestat
| Article | Year |
|---|---|
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
1 other study(ies) available for al-01567 and ponalrestat
| Article | Year |
|---|---|
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners.
Topics: Alcohol Dehydrogenase; Aldehyde Reductase; Animals; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Female; Humans; Kidney; Lens, Crystalline; Molecular Structure; Placenta; Pyrrolidonecarboxylic Acid; Sciatic Nerve; Sorbitol; Structure-Activity Relationship; Swine | 1991 |