Page last updated: 2024-09-03

al-01567 and hydantoins

al-01567 has been researched along with hydantoins in 11 studies

Compound Research Comparison

Studies
(al-01567)
Trials
(al-01567)
Recent Studies (post-2010)
(al-01567)
Studies
(hydantoins)
Trials
(hydantoins)
Recent Studies (post-2010) (hydantoins)
13023,40480435

Protein Interaction Comparison

ProteinTaxonomyal-01567 (IC50)hydantoins (IC50)
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.062

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Griffin, BW; McNatt, LG1
Hockwin, O; Korte, I; Ohrloff, C; Wegener, A1
Chandler, ML; Griffin, BW; McNatt, LG; York, BM1
Lou, MF; Mahendroo, PP; Thomas, DM1
Dickerson, JE; Garadi, R; Lou, MF; York, BM1
Brazzell, RK; Dobbs, RE; McCue, BA; Park, YH; York, BM1
Kador, PF; Kinoshita, JH; Sharpless, NE1
Eisenhofer, G; Harvey-White, J; Kirk, K; Kopin, IJ; Lamensdorf, I; Nechustan, A1
Aitken, DA; Crossley, JA; Dunstan, FD; Nix, AB; Spencer, K; Williams, K1
Cartault, F; Cormier-Daire, V; Doray, B; Jacquemont, ML; Laville, JM; Munier, P; Munnich, A; Payet, C; Randrianaivo, H; Vellayoudom, J1
Cao, J; Chen, H; Han, F; Hao, X; Huang, Y; Jiang, X; Liu, J; Liu, W; Yang, J; Yin, L; Zhang, H1

Reviews

1 review(s) available for al-01567 and hydantoins

ArticleYear
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution

1985

Other Studies

10 other study(ies) available for al-01567 and hydantoins

ArticleYear
Characterization of the reduction of 3-acetylpyridine adenine dinucleotide phosphate by benzyl alcohol catalyzed by aldose reductase.
    Archives of biochemistry and biophysics, 1986, Volume: 246, Issue:1

    Topics: Alcohols; Aldehyde Reductase; Aldehydes; Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Catalysis; Fluorenes; Hydantoins; Kinetics; Lens, Crystalline; NADP; Oxidation-Reduction; Rats; Spectrometry, Fluorescence; Spectrophotometry; Sugar Alcohol Dehydrogenases

1986
[Aldose reductase inhibitor--a new way for preventing diabetic lens changes?].
    Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 189, Issue:5

    Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Type 1; Fluorenes; Humans; Hydantoins; Rats; Sugar Alcohol Dehydrogenases

1986
Effects of two new aldose reductase inhibitors, AL-1567 and AL-1576, in diabetic rats.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:5

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Female; Fluorenes; Humans; Hydantoins; In Vitro Techniques; Kinetics; Lens, Crystalline; Male; Placenta; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases

1987
Dynamic phosphorus-31 NMR study of sugar cataract and its prevention in rat lenses with aldose reductase inhibitors.
    Experimental eye research, 1988, Volume: 46, Issue:1

    Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Cataract; Culture Techniques; Fluorenes; Hydantoins; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphorylcholine; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Time Factors; Xylose

1988
Glutathione depletion in the lens of galactosemic and diabetic rats.
    Experimental eye research, 1988, Volume: 46, Issue:4

    Topics: Aldehyde Reductase; Aminoisobutyric Acids; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Fluorenes; Galactitol; Galactosemias; Glutathione; Glutathione Reductase; Hydantoins; Lens, Crystalline; Male; NAD; NADP; Rats; Rats, Inbred Strains; Sorbitol

1988
High-performance liquid chromatographic assay of the aldose reductase inhibitor spiro-(2-fluoro-9H-fluorene-9,4'-imidazolidine)-2',5'-dione (AL01567) in plasma and urine and its pharmacokinetics in humans.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:7

    Topics: Adult; Aldehyde Reductase; Chromatography, High Pressure Liquid; Double-Blind Method; Fluorenes; Humans; Hydantoins; Male; Spectrophotometry, Ultraviolet; Sugar Alcohol Dehydrogenases

1988
3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells.
    Brain research, 2000, Jun-23, Volume: 868, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Dopamine; Energy Metabolism; Enzyme Inhibitors; Estrogens, Non-Steroidal; Fluorenes; Hydantoins; Isoflavones; Mitochondria; Neurons; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; PC12 Cells; Phenylethyl Alcohol; Rats; Rotenone

2000
The effect of temporal variation in biochemical markers of trisomy 21 across the first and second trimesters of pregnancy on the estimation of individual patient-specific risks and detection rates for Down's syndrome.
    Annals of clinical biochemistry, 2003, Volume: 40, Issue:Pt 3

    Topics: alpha-Fetoproteins; Biomarkers; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Down Syndrome; False Positive Reactions; Female; Fluorenes; Gestational Age; Humans; Hydantoins; Odds Ratio; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy-Associated Plasma Protein-A; Prenatal Diagnosis; Risk Assessment

2003
Expanding the clinical spectrum of B4GALT7 deficiency: homozygous p.R270C mutation with founder effect causes Larsen of Reunion Island syndrome.
    European journal of human genetics : EJHG, 2015, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Child; Facies; Female; Fluorenes; Founder Effect; Galactosyltransferases; Gene Frequency; Homozygote; Humans; Hydantoins; Male; Middle Aged; Mutation; Osteochondrodysplasias; Pedigree; Phenotype; Sequence Analysis, DNA; Young Adult

2015
ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway.
    Journal of experimental & clinical cancer research : CR, 2017, Nov-28, Volume: 36, Issue:1

    Topics: beta Catenin; Breast Neoplasms; Disease Progression; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Female; Fluorenes; Humans; Hydantoins; Serine; Transcription Factors; Wnt Signaling Pathway

2017