ajugarin i has been researched along with chloroquine in 2 studies
*Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. [MeSH]
*Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. [MeSH]
| Studies (ajugarin i) | Trials (ajugarin i) | Recent Studies (post-2010) (ajugarin i) | Studies (chloroquine) | Trials (chloroquine) | Recent Studies (post-2010) (chloroquine) |
|---|---|---|---|---|---|
| 6 | 0 | 2 | 16,405 | 763 | 4,029 |
| Protein | Taxonomy | ajugarin i (IC50) | chloroquine (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 43 | |
| Spike glycoprotein | Betacoronavirus England 1 | 5.47 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 5.47 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 5.47 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0301 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 7 | |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2383 | |
| Procathepsin L | Homo sapiens (human) | 5.47 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 5.47 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | 3.58 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.375 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 1.5 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.27 | |
| Beta-secretase 1 | Homo sapiens (human) | 7 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.503 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 6.235 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.02 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Busson, R; Chepkwony, H; De Witte, P; Govaerts, C; Hoogmartens, J; Hoornaert, G; Janssens, L; Kuria, KA; Laekeman, G; Maes, L; Quirynen, L; Roets, E; Zupko, I | 1 |
| Cocquyt, K; Cos, P; Herdewijn, P; Laekeman, G; Maes, L; Van den Steen, PE | 1 |
1 review(s) available for ajugarin i and chloroquine
| Article | Year |
|---|---|
Ajuga remota Benth.: from ethnopharmacology to phytomedical perspective in the treatment of malaria.
Topics: Ajuga; Antimalarials; Artemisinins; Chloroquine; Dehydroepiandrosterone Sulfate; Diterpenes; Ergosterol; Ethnopharmacology; Lactones; Malaria; Molecular Structure; Phytosterols; Plant Preparations; Plasmodium; Species Specificity | 2011 |
1 other study(ies) available for ajugarin i and chloroquine
| Article | Year |
|---|---|
The antiplasmodial activity of isolates from Ajuga remota.
Topics: Animals; Antimalarials; Antineoplastic Agents; Chloroquine; Chromatography, Thin Layer; Diterpenes; Drug Resistance, Microbial; Drug Screening Assays, Antitumor; Ergosterol; Fluorouracil; Humans; In Vitro Techniques; Inhibitory Concentration 50; Kenya; L-Lactate Dehydrogenase; Lamiaceae; Plants, Medicinal; Plasmodium falciparum; Skin Neoplasms; Tumor Cells, Cultured | 2002 |