Compounds > ahn 086
Page last updated: 2024-09-03

ahn 086 and ro 5-4864

ahn 086 has been researched along with ro 5-4864 in 5 studies

Compound Research Comparison

Studies
(ahn 086)		Trials
(ahn 086)		Recent Studies (post-2010)
(ahn 086)		Studies
(ro 5-4864)		Trials
(ro 5-4864)		Recent Studies (post-2010) (ro 5-4864)
1000593054

Protein Interaction Comparison

ProteinTaxonomyahn 086 (IC50)ro 5-4864 (IC50)
Translocator proteinRattus norvegicus (Norway rat)0.034
Translocator proteinMus musculus (house mouse)0.01

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bravo, C; Chiang, PK; Gutiérrez, J; Moreno-Sánchez, R; Newman, AH1
Basile, AS; Bravo, C; Chiang, PK; Hogue, BA; Moreno-Sánchez, R; Newman, AH1
Basile, AS; Bolger, GT; Lueddens, HW; Newman, AH; Rice, KC; Skolnick, P1
Lueddens, HW; Newman, AH; Rice, KC; Skolnick, P2

Other Studies

5 other study(ies) available for ahn 086 and ro 5-4864

ArticleYear
Release of Ca2+ from heart and kidney mitochondria by peripheral-type benzodiazepine receptor ligands.
    The International journal of biochemistry, 1991, Volume: 23, Issue:2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Calcium; Clonazepam; Kidney; Magnesium; Mitochondria; Mitochondria, Heart; Rats; Rats, Inbred Strains; Receptors, GABA-A; Strontium

1991
Inhibition of substrate oxidation in mitochondria by the peripheral-type benzodiazepine receptor ligand AHN 086.
    Biochemical pharmacology, 1991, May-15, Volume: 41, Issue:10

    Topics: Adenosine Triphosphate; Animals; Benzodiazepinones; Binding Sites; Dose-Response Relationship, Drug; Isoquinolines; Kidney; Male; Mitochondria, Heart; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Rats; Rats, Inbred Strains; Receptors, GABA-A

1991
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzodiazepinones; Brain; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Nitrendipine; Receptors, GABA-A

1989
Novel irreversible ligands specific for "peripheral" type benzodiazepine receptors: (+/-)-, (+)-, and (-)-1-(2-chlorophenyl)-N-(1-methylpropyl)-N- (2-isothiocyanatoethyl)-3-isoquinolinecarboxamide and 1-(2-isothiocyanatoethyl)-7-chloro-1,3-dihydro-5-(4-ch
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Animals; Benzodiazepinones; Brain; Hydrogen-Ion Concentration; Isoquinolines; Kidney; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereoisomerism

1987
Synthesis and biochemical characterization of two novel irreversible ligands specific for "peripheral" benzodiazepine receptors.
    NIDA research monograph, 1987, Volume: 76

    Topics: Animals; Benzodiazepinones; Brain; Chemical Phenomena; Chemistry; Isoquinolines; Kidney; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A

1987