Page last updated: 2024-09-04

aguerin b and fluorouracil

aguerin b has been researched along with fluorouracil in 1 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies
(aguerin b)
Trials
(aguerin b)
Recent Studies (post-2010)
(aguerin b)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
70645,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomyaguerin b (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adinolfi, B; Chicca, A; Ertugrul, K; Flamini, G; Nieri, P; Tebano, M1

Other Studies

1 other study(ies) available for aguerin b and fluorouracil

ArticleYear
Anti-proliferative activity of aguerin B and a new rare nor-guaianolide lactone isolated from the aerial parts of Centaurea deflexa.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Centaurea; DNA Fragmentation; Humans; Lactones; Plant Components, Aerial; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Guaiane; Structure-Activity Relationship

2011