Page last updated: 2024-08-23

agn 2979 and 2-piperidone

agn 2979 has been researched along with 2-piperidone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's5 (55.56)18.2507
2000's3 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawasaki, H; Takasaki, K1
Boadle-Biber, MC; Phan, TH1
Gittos, MW2
Benes, CO; Cutler, NR; Doss, MG; Howard, SF; Macpherson, AE; Sramek, JJ1
Hara, C; Ogawa, N; Takaki, S1
Gittos, MW; Papp, M1
Diksic, M; Gittos, M; Hasegawa, S; Kanemaru, K1
Diksic, M; Kanemaru, K; Nishi, K1

Trials

1 trial(s) available for agn 2979 and 2-piperidone

ArticleYear
An evaluation of the anxiolytic SC 48,274 in generalized anxiety disorder (GAD)
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Double-Blind Method; Female; Humans; Male; Piperidones; Psychiatric Status Rating Scales

1994

Other Studies

8 other study(ies) available for agn 2979 and 2-piperidone

ArticleYear
[Electroencephalographic study with SC-48274, a novel nonbenzodiazepine anxiolytic in conscious rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Diazepam; Electroencephalography; Male; Piperidones; Rabbits

1991
AGN 2979 [3(3-methoxyphenyl)-3-(3-dimethylaminopropyl)-4, 4-dimethylpiperidine-2,6-dione]. An inhibitor of the activation of tryptophan hydroxylase.
    Biochemical pharmacology, 1986, May-01, Volume: 35, Issue:9

    Topics: Animals; Brain Stem; Calmodulin; Enzyme Activation; Gallic Acid; Haloperidol; Male; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Xanthines

1986
The anxiolytic SC 48274 (AGN 2979; BTG 1501) in generalized anxiety disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:8

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperidones; Psychiatric Status Rating Scales; Treatment Outcome

1994
The anxiolytic SC 48274 (AGN 2979; BTG 1501) in generalized anxiety disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Humans; Piperidones

1994
Anxiolytic activity of SC-48274 compared with those of buspirone and diazepam in experimental anxiety models.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Buspirone; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Mice, Inbred ICR; Piperidones; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

1993
Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:5

    Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Depression; Enzyme Inhibitors; Imipramine; Male; Piperidones; Rats; Rats, Wistar; Stress, Psychological; Tryptophan Hydroxylase

2001
The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with alpha-[14C]methyl-L-tryptophan: an autoradiographic study.
    Brain research bulletin, 2005, Oct-15, Volume: 67, Issue:3

    Topics: Analysis of Variance; Animals; Autoradiography; Brain; Carbon Isotopes; Enzyme Inhibitors; Male; Piperidones; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan

2005
AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats.
    Neurochemistry international, 2009, Volume: 55, Issue:7

    Topics: Animals; Autoradiography; Brain Chemistry; Depression; Enzyme Activation; Linear Models; Piperidones; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase

2009