agn 2979 has been researched along with 2-piperidone in 9 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (11.11) | 18.7374 |
1990's | 5 (55.56) | 18.2507 |
2000's | 3 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kawasaki, H; Takasaki, K | 1 |
Boadle-Biber, MC; Phan, TH | 1 |
Gittos, MW | 2 |
Benes, CO; Cutler, NR; Doss, MG; Howard, SF; Macpherson, AE; Sramek, JJ | 1 |
Hara, C; Ogawa, N; Takaki, S | 1 |
Gittos, MW; Papp, M | 1 |
Diksic, M; Gittos, M; Hasegawa, S; Kanemaru, K | 1 |
Diksic, M; Kanemaru, K; Nishi, K | 1 |
1 trial(s) available for agn 2979 and 2-piperidone
Article | Year |
---|---|
An evaluation of the anxiolytic SC 48,274 in generalized anxiety disorder (GAD)
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Double-Blind Method; Female; Humans; Male; Piperidones; Psychiatric Status Rating Scales | 1994 |
8 other study(ies) available for agn 2979 and 2-piperidone
Article | Year |
---|---|
[Electroencephalographic study with SC-48274, a novel nonbenzodiazepine anxiolytic in conscious rabbits].
Topics: Animals; Anti-Anxiety Agents; Buspirone; Diazepam; Electroencephalography; Male; Piperidones; Rabbits | 1991 |
AGN 2979 [3(3-methoxyphenyl)-3-(3-dimethylaminopropyl)-4, 4-dimethylpiperidine-2,6-dione]. An inhibitor of the activation of tryptophan hydroxylase.
Topics: Animals; Brain Stem; Calmodulin; Enzyme Activation; Gallic Acid; Haloperidol; Male; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Xanthines | 1986 |
The anxiolytic SC 48274 (AGN 2979; BTG 1501) in generalized anxiety disorder.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperidones; Psychiatric Status Rating Scales; Treatment Outcome | 1994 |
The anxiolytic SC 48274 (AGN 2979; BTG 1501) in generalized anxiety disorder.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Humans; Piperidones | 1994 |
Anxiolytic activity of SC-48274 compared with those of buspirone and diazepam in experimental anxiety models.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Buspirone; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Mice, Inbred ICR; Piperidones; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological | 1993 |
Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Depression; Enzyme Inhibitors; Imipramine; Male; Piperidones; Rats; Rats, Wistar; Stress, Psychological; Tryptophan Hydroxylase | 2001 |
The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with alpha-[14C]methyl-L-tryptophan: an autoradiographic study.
Topics: Analysis of Variance; Animals; Autoradiography; Brain; Carbon Isotopes; Enzyme Inhibitors; Male; Piperidones; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2005 |
AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats.
Topics: Animals; Autoradiography; Brain Chemistry; Depression; Enzyme Activation; Linear Models; Piperidones; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2009 |