agn 193109 has been researched along with tretinoin in 18 studies
| Studies (agn 193109) | Trials (agn 193109) | Recent Studies (post-2010) (agn 193109) | Studies (tretinoin) | Trials (tretinoin) | Recent Studies (post-2010) (tretinoin) |
|---|---|---|---|---|---|
| 33 | 0 | 1 | 23,654 | 1,083 | 6,085 |
| Protein | Taxonomy | agn 193109 (IC50) | tretinoin (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.18 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.275 | |
| Retinoic acid receptor alpha | Homo sapiens (human) | 2.2542 | |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Retinoic acid receptor beta | Homo sapiens (human) | 0.7537 | |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.0057 | |
| Retinoic acid receptor gamma | Homo sapiens (human) | 0.0064 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | 0.004 | |
| Retinoic acid receptor beta | Mus musculus (house mouse) | 0.005 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.576 | |
| Nuclear receptor ROR-alpha | Homo sapiens (human) | 0.1995 | |
| Alpha-synuclein | Homo sapiens (human) | 3 | |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.5233 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.358 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.35 | |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | 0.1995 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | 0.82 | |
| 60 kDa chaperonin | Escherichia coli | 6.7 | |
| 10 kDa chaperonin | Escherichia coli | 6.7 | |
| Nuclear receptor ROR-beta | Homo sapiens (human) | 0.1259 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chandraratna, RA; Gillett, SJ; Johnson, AT; Klein, ES; Pino, ME; Song, TK; Wang, L | 1 |
| Chandraratna, RA; Gillett, SJ; Johnson, AT; Wang, L | 1 |
| Chandraratna, RA; Thacher, SM; Vasudevan, J | 1 |
| Beard, RL; Chandraratna, RA; Escobar, M; Klein, ES; Standeven, AM | 1 |
| Chandraratna, RA; Duong, TT; Johnson, AT; Khalifa, B; Klein, ES; Teng, M; Wang, L | 1 |
| Angulo, A; Chandraratna, RA; Ghazal, P; LeBlanc, JF | 1 |
| Gañan, Y; Hurle, JM; Macias, D; Merino, R; Rodriguez-Leon, J; Santesteban, E | 1 |
| Barnes, KM; Baron, J; De Luca, F; Mancilla, EE; Mericq, V; Uyeda, JA; Yanovski, JA; Zile, MH | 1 |
| Bernstein, ID; Collins, SJ; Purton, LE | 1 |
| Furusu, A; Kitamura, M; Konta, T; Nakayama, K; Xu, Q | 1 |
| Chandraratna, RA; Gabriel, JL; Gambone, CJ; Kochhar, DM; Sheikh, SN; Soprano, DR; Soprano, KJ | 1 |
| Kintner, C; Moreno, TA | 1 |
| Bunce, CM; Hayden, RE; Mountford, JC; Vanin, EF | 1 |
| Bowles, J; Chawengsaksophak, K; Hamada, H; Knight, D; Koopman, P; Mamiya, S; Richman, J; Rossant, J; Smith, C; Wilhelm, D; Wilson, MJ; Yashiro, K | 1 |
| Cong, Z; Gilliland, KL; Nelson, AM; Thiboutot, DM | 1 |
| Manikam, SD; Manikam, ST; Stanslas, J | 1 |
| Cheng, Y; Lotan, R; Tao, Q; Wang, Y; Ye, X | 1 |
| Engberg, N; Hansson, M; Kahn, M; Petersen, DR; Serup, P | 1 |
1 review(s) available for agn 193109 and tretinoin
| Article | Year |
|---|---|
Therapeutic applications for ligands of retinoid receptors.
Topics: Animals; Drug Design; Humans; Ligands; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship | 2000 |
17 other study(ies) available for agn 193109 and tretinoin
| Article | Year |
|---|---|
Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors.
Topics: Animals; Dose-Response Relationship, Drug; Naphthalenes; Receptors, Retinoic Acid; Structure-Activity Relationship | 1995 |
High affinity retinoic acid receptor antagonists: analogs of AGN 193109.
Topics: Naphthalenes; Receptors, Retinoic Acid; Structure-Activity Relationship | 1999 |
Phenylcyclohexene and phenylcyclohexadiene substituted compounds having retinoid antagonist activity.
Topics: Animals; Benzoates; Cyclohexanes; Dermatitis, Irritant; Disease Models, Animal; Mice; Receptors, Retinoic Acid; Retinoids | 2001 |
Identification of highly potent retinoic acid receptor alpha-selective antagonists.
Topics: Animals; Benzoates; Cell Line; Chromans; Haplorhini; Kinetics; Naphthalenes; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; Transcriptional Activation; Tretinoin | 1997 |
Ligand induction of retinoic acid receptors alters an acute infection by murine cytomegalovirus.
Topics: 3T3 Cells; Administration, Oral; Animals; Benzoates; Female; Herpesviridae Infections; Ligands; Mice; Mice, Inbred BALB C; Muromegalovirus; Naphthalenes; Receptors, Retinoic Acid; Retinoids; Tretinoin; Virus Replication | 1998 |
Retinoic acid regulates programmed cell death through BMP signalling.
Topics: Animals; Apoptosis; Bone Morphogenetic Proteins; Carrier Proteins; Chick Embryo; Gene Expression Regulation, Developmental; In Situ Nick-End Labeling; Limb Buds; Naphthalenes; Proteins; Receptors, Retinoic Acid; Signal Transduction; Toes; Tretinoin | 1999 |
Retinoic acid is a potent regulator of growth plate chondrogenesis.
Topics: Alkaline Phosphatase; Animals; Bone and Bones; Bone Development; Chondrogenesis; Growth Plate; Histocytochemistry; Male; Metatarsal Bones; Naphthalenes; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Sulfates; Thymidine; Tretinoin | 2000 |
All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells.
Topics: Animals; Antigens, Ly; Bone Marrow Transplantation; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Naphthalenes; Proto-Oncogene Proteins c-kit; Receptors, Retinoic Acid; Tretinoin | 2000 |
Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid.
Topics: Animals; Apoptosis; Cells, Cultured; Gene Expression Regulation; Genes, fos; Genes, jun; Glomerular Mesangium; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Recombinant Proteins; Retinoid X Receptors; Transcription Factor AP-1; Transcription Factors; Transfection; Tretinoin | 2001 |
The synthetic retinoid AGN 193109 but not retinoic acid elevates CYP1A1 levels in mouse embryos and Hepa-1c1c7 cells.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Cells, Cultured; Cytochrome P-450 CYP1A1; DNA-Binding Proteins; Embryo, Mammalian; Female; Male; Mice; Naphthalenes; Receptors, Aryl Hydrocarbon; Receptors, Retinoic Acid; RNA, Messenger; Transcription Factors; Tretinoin | 2001 |
Regulation of segmental patterning by retinoic acid signaling during Xenopus somitogenesis.
Topics: Animals; Animals, Genetically Modified; Antibodies; Body Patterning; Cells, Cultured; Cycloheximide; Drug Interactions; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Immunohistochemistry; Membrane Proteins; Models, Biological; Muscles; Naphthalenes; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Receptors, Notch; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Signal Transduction; Somites; Thy-1 Antigens; Time Factors; Transfection; Tretinoin; Xenopus; Xenopus laevis; Xenopus Proteins | 2004 |
All-trans retinoic acid increases transgene expression in MSCV-transduced cells, via a mechanism that is retinoid receptor dependent but independent of cellular differentiation.
Topics: Animals; Antineoplastic Agents; Base Sequence; Cell Differentiation; Green Fluorescent Proteins; HL-60 Cells; Humans; K562 Cells; Leukemia Virus, Murine; Membrane Glycoproteins; Mice; Molecular Sequence Data; Naphthalenes; Receptors, Retinoic Acid; Stem Cells; Transcription Factors; Transduction, Genetic; Transgenes; Tretinoin; Viral Envelope Proteins | 2005 |
Retinoid signaling determines germ cell fate in mice.
Topics: Animals; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation, Developmental; Genes, Reporter; Germ Cells; In Situ Hybridization; Lac Operon; Male; Meiosis; Mesonephros; Mice; Mice, Knockout; Naphthalenes; Oogenesis; Ovary; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Sertoli Cells; Sex Characteristics; Signal Transduction; Spermatogenesis; Testis; Tissue Culture Techniques; Tretinoin | 2006 |
13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes.
Topics: Alitretinoin; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cell Line; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; DNA; Humans; In Situ Nick-End Labeling; Isotretinoin; Naphthalenes; Sebaceous Glands; Tretinoin | 2006 |
Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis.
Topics: Andrographis; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Promyelocytic, Acute; Microscopy, Fluorescence; Molecular Structure; Naphthalenes; Plant Extracts; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tretinoin | 2009 |
Mechanisms underlying the induction of the putative human tumor suppressor GPRC5A by retinoic acid.
Topics: Base Sequence; Binding Sites; Cell Line, Tumor; Conserved Sequence; DNA; Exons; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Introns; Luciferases; Molecular Sequence Data; Naphthalenes; Neoplasm Proteins; Plasmids; Promoter Regions, Genetic; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; RNA, Messenger; Sequence Homology, Nucleic Acid; TATA Box; Transcription Factors; Transcription Initiation Site; Transcription, Genetic; Transfection; Tretinoin | 2009 |
Retinoic acid synthesis promotes development of neural progenitors from mouse embryonic stem cells by suppressing endogenous, Wnt-dependent nodal signaling.
Topics: Acyclic Monoterpenes; Animals; Cell Differentiation; Cells, Cultured; Disulfiram; Embryonic Stem Cells; Enzyme Inhibitors; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Genes, Reporter; Mesoderm; Mice; Monoterpenes; Naphthalenes; Neural Plate; Neurons; Nodal Protein; Receptors, Retinoic Acid; Signal Transduction; Time Factors; Transfection; Tretinoin; Vitamin A; Wnt Proteins | 2010 |