agmatidine has been researched along with 2-4-diaminopyrimidine* in 1 studies
1 other study(ies) available for agmatidine and 2-4-diaminopyrimidine
Article | Year |
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Efficient preparation of 2,4-diaminopyrimidine nucleosides: total synthesis of lysidine and agmatidine.
An efficient route for the synthesis of 2,4-diaminopyrimidine ribosides from cytidine is described consisting of six steps with overall yields >50% and only one chromatographic step. The key amine addition step utilizes LiCl and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) to ensure clean conversion to a single tautomeric product. This route has been used to prepare the modified tRNA nucleosides lysidine and agmatidine in quantities suitable for structural characterization. Topics: Cytidine; Lysine; Molecular Structure; Pyrimidine Nucleosides; Pyrimidines; RNA | 2012 |