agathisflavone and 4-hydroxybenzoic-acid

agathisflavone has been researched along with 4-hydroxybenzoic-acid* in 1 studies

Other Studies

1 other study(ies) available for agathisflavone and 4-hydroxybenzoic-acid

Article	Year
(6R,9S)-6"-(4"-hydroxybenzoyl)-roseoside, a new megastigmane derivative from Ouratea polyantha and its effect on hepatic glucose-6-phosphatase. Natural product communications, 2012, Volume: 7, Issue:8 A new megastigmane derivative, (6R,9S)-6'-(4"-hydroxybenzoyl)-roseoside (1) and two known compounds, the biflavoneagathisflavone (2) and 4-hydroxybenzoic acid (3) were isolated and purified from leaves and stems of Ouratea polyantha Engl. Agathisflavone was isolated in a single high-speed countercurrent chromatography run, while the megastigmane was purified in two steps, by using a combination of high-speed countercurrent chromatography and analytical column chromatography. All structures were elucidated on the basis of spectral evidence and comparison with literature data. Compound 1 was characterized by [alpha]D20, UV-Vis, IR, MS, 1H NMR, 13C NMR, HMQC, HMBC, COSY and NOESY. Compounds 1 and 2 showed an inhibitory effect of 63.6 and 13.7% on the G-6-Pase intact microsomes, respectively. Topics: Animals; Biflavonoids; Glucose-6-Phosphatase; Male; Microsomes, Liver; Molecular Structure; Norisoprenoids; Ochnaceae; Parabens; Plant Leaves; Plant Stems; Rats; Rats, Sprague-Dawley	2012

Article

Year

(6R,9S)-6"-(4"-hydroxybenzoyl)-roseoside, a new megastigmane derivative from Ouratea polyantha and its effect on hepatic glucose-6-phosphatase.

Natural product communications, 2012, Volume: 7, Issue:8

A new megastigmane derivative, (6R,9S)-6'-(4"-hydroxybenzoyl)-roseoside (1) and two known compounds, the biflavoneagathisflavone (2) and 4-hydroxybenzoic acid (3) were isolated and purified from leaves and stems of Ouratea polyantha Engl. Agathisflavone was isolated in a single high-speed countercurrent chromatography run, while the megastigmane was purified in two steps, by using a combination of high-speed countercurrent chromatography and analytical column chromatography. All structures were elucidated on the basis of spectral evidence and comparison with literature data. Compound 1 was characterized by [alpha]D20, UV-Vis, IR, MS, 1H NMR, 13C NMR, HMQC, HMBC, COSY and NOESY. Compounds 1 and 2 showed an inhibitory effect of 63.6 and 13.7% on the G-6-Pase intact microsomes, respectively.

Topics: Animals; Biflavonoids; Glucose-6-Phosphatase; Male; Microsomes, Liver; Molecular Structure; Norisoprenoids; Ochnaceae; Parabens; Plant Leaves; Plant Stems; Rats; Rats, Sprague-Dawley

2012