ag 1879 and tyrosine

Topics: Antigens, CD; Antineoplastic Agents; Cadherins; Capillary Permeability; Cells, Cultured; Dextrans; Endothelium, Vascular; Fluorescein-5-isothiocyanate; Humans; Phosphorylation; Pyrimidines; src-Family Kinases; Tumor Necrosis Factor-alpha; Tyrosine; Umbilical Veins

Topics: Acetophenones; Angiogenesis Inducing Agents; Animals; Becaplermin; Benzopyrans; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Isoenzymes; Ligands; Muscle, Smooth, Vascular; Oxidants; Oxidation-Reduction; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-delta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Platelet-Derived Growth Factor beta; src-Family Kinases; Transcriptional Activation; Tyrosine; Tyrphostins

Topics: Animals; Cells, Cultured; Clathrin Heavy Chains; Endocytosis; Hydrogen Peroxide; Islets of Langerhans; Mice; Oxidants; Oxidative Stress; Phosphorylation; Protein Transport; Pyrimidines; src-Family Kinases; Transferrin; Tyrosine

Topics: Animals; Cell Communication; Cells, Cultured; Connexin 43; Epidermal Growth Factor; Eukaryotic Cells; Gap Junctions; Isoquinolines; Membrane Potentials; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Oncogene Protein pp60(v-src); Phosphorylation; Pyrimidines; Quaternary Ammonium Compounds; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, Differentiation; COS Cells; Cytoskeletal Proteins; Drosophila Proteins; Focal Adhesion Kinase 2; Interleukin-1 Receptor-Associated Kinases; Lipopeptides; Macrophages; Membrane Glycoproteins; Myeloid Differentiation Factor 88; Oligopeptides; Paxillin; Phosphoproteins; Protein Kinases; Protein-Tyrosine Kinases; Pyrimidines; Rats; Receptors, Cell Surface; Receptors, Immunologic; src-Family Kinases; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Tyrosine

Topics: Amino Acid Motifs; Animals; Casein Kinase II; Catalysis; Catalytic Domain; Enzyme Inhibitors; Humans; Jurkat Cells; Mutation; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrimidines; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src-Family Kinases; Trypsin; Tyrosine

Topics: Amino Acid Sequence; Amino Acid Substitution; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans; I-kappa B Kinase; Isoenzymes; Membrane Proteins; Molecular Sequence Data; NF-kappa B; Phenylalanine; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine

Topics: Cell Line; Cell Membrane; Down-Regulation; Enzyme Activation; Ephrin-A1; Humans; Jurkat Cells; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Pyrimidines; Receptor, EphA3; Receptor, EphA4; Receptors, Eph Family; Signal Transduction; src-Family Kinases; T-Lymphocyte Subsets; Transfection; Tyrosine; Ubiquitin-Protein Ligases

Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; GTPase-Activating Proteins; Humans; Lysophospholipids; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Sphingosine; Thrombin; Tyrosine

Topics: Animals; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Immunoblotting; Neutrophils; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C beta; Protein Transport; Protein Tyrosine Phosphatases; Pyrimidines; src-Family Kinases; Swine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates

Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens; Carrier Proteins; Cell Degranulation; Cell Line; Enzyme Activation; Enzyme Inhibitors; Humans; Mast Cells; Membrane Proteins; Mice; Phosphoproteins; Phosphorylation; Proteins; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptors, IgE; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Stem Cell Factor; Stilbenes; Tyrosine

Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Nucleus; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Gemcitabine; Genes, Dominant; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Pyrimidines; Ribonucleoside Diphosphate Reductase; src-Family Kinases; Transcription Factors; Tyrosine

Topics: Cell Line; Cell Survival; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Lymphedema; Mutation, Missense; Oncogene Protein v-akt; Oxidative Stress; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Pyrimidines; Recombinant Proteins; Retroviridae Proteins, Oncogenic; Signal Transduction; src Homology Domains; src-Family Kinases; Tyrosine; Vanadates; Vascular Endothelial Growth Factor Receptor-3

Topics: Antigens, CD; beta-Cyclodextrins; Cell Membrane; Cross-Linking Reagents; Cytoplasm; Cytoplasmic Granules; Detergents; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Models, Biological; Neutrophils; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Pyrimidines; Receptors, IgG; Receptors, Immunologic; Solubility; src-Family Kinases; Syk Kinase; Tyrosine

Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Humans; Mast Cells; Phospholipase D; Phosphorylation; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Pyrimidines; Rats; Receptors, IgE; RNA, Small Interfering; src-Family Kinases; Tyrosine; Vanadates

Topics: Animals; Lipopolysaccharides; Male; Neutrophils; NF-kappa B; Oxidative Stress; Phosphorylation; Protein Transport; Pyrimidines; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Shock, Hemorrhagic; src-Family Kinases; Tyrosine

Topics: Animals; Animals, Newborn; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Mice; Muscle, Skeletal; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrimidines; Receptor, Insulin; Signal Transduction; src-Family Kinases; Tyrosine

Topics: Actins; Adenoviridae; Binding Sites; Cell Movement; Cell Proliferation; CSK Tyrosine-Protein Kinase; Cytoskeleton; DNA, Complementary; Genes, Dominant; HeLa Cells; Humans; Microfilament Proteins; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; src-Family Kinases; Time Factors; Transfection; Tyrosine

Topics: Animals; Binding Sites; Cell Line, Transformed; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Epitopes; Genes, Dominant; Hydrogen Peroxide; Immunoblotting; Immunoprecipitation; Mice; Models, Biological; NIH 3T3 Cells; Phenylalanine; Phosphorylation; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; Pyrimidines; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tyrosine

Topics: Biotinylation; Blotting, Western; Calreticulin; CD8 Antigens; Cell Proliferation; Collodion; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Genes, MHC Class I; Glycosylation; Humans; Immunoprecipitation; Kinetics; Lymphocyte Activation; Major Histocompatibility Complex; Peptides; Phosphorylation; Protein Folding; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; T-Lymphocytes; Time Factors; Tyrosine

Topics: Animals; Blotting, Western; Brain; Cell Adhesion Molecules; Cell Line; Chickens; DCC Receptor; Drug Interactions; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Cones; Humans; Immunoprecipitation; Larva; Microinjections; Mutagenesis; Nerve Growth Factors; Netrin-1; Neurons; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Receptors, Cell Surface; Signal Transduction; Spinal Cord; src-Family Kinases; Time Factors; Transfection; Tumor Suppressor Proteins; Tyrosine; Xenopus

Topics: Alanine; Amino Acid Sequence; Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cell Movement; CHO Cells; Cricetinae; Cytoskeletal Proteins; DNA; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Humans; Lysine; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; NIH 3T3 Cells; Paxillin; Phosphoproteins; Phosphorylation; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Sequence Homology, Amino Acid; src-Family Kinases; Time Factors; Transfection; Tyrosine

Topics: Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; MAP Kinase Signaling System; Marine Toxins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neocortex; Neurons; Oxocins; Phosphorylation; Pregnancy; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Channels; src-Family Kinases; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Aorta; Blotting, Western; Cattle; Cells, Cultured; Cinnamates; DNA, Complementary; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoprecipitation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; RNA, Small Interfering; Shear Strength; Signal Transduction; Stress, Mechanical; Time Factors; Transfection; Tyrosine; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2

Topics: Animals; Brain; Capillaries; Cells, Cultured; Collagen; DNA-Binding Proteins; DNA, Complementary; Down-Regulation; Drug Combinations; Endothelium, Vascular; Eye Proteins; Fibroblast Growth Factor 2; Fluorescent Antibody Technique, Indirect; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Immunoblotting; Immunoprecipitation; Laminin; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Nerve Growth Factors; Nuclear Proteins; Phosphorylation; Protein Structure, Tertiary; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Pyrimidines; Recombinant Proteins; Repressor Proteins; Serpins; Signal Transduction; src-Family Kinases; Transfection; Tyrosine; Umbilical Veins

Topics: Blotting, Western; Cell Line; CSK Tyrosine-Protein Kinase; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Green Fluorescent Proteins; NADPH Oxidases; Oxygen; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pulmonary Artery; Pyrimidines; Reactive Oxygen Species; Recombinant Fusion Proteins; RNA, Small Interfering; src-Family Kinases; Superoxides; Transfection; Tyrosine

Topics: Animals; Blotting, Western; Cell Proliferation; Enzyme Inhibitors; Epithelium; Lens, Crystalline; Organ Culture Techniques; Phosphorylation; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Swine; Tyrosine; Tyrphostins

Topics: Animals; CD3 Complex; Clone Cells; Enzyme Activation; Humans; Immune Sera; Immunosuppressive Agents; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Protein-Tyrosine Kinases; Pyrimidines; Receptor-CD3 Complex, Antigen, T-Cell; src-Family Kinases; T-Lymphocytes; Tyrosine; ZAP-70 Protein-Tyrosine Kinase

Topics: Animals; Calcium; Cattle; Cells, Cultured; Chlorocebus aethiops; COS Cells; Immunoblotting; Immunoprecipitation; Inflammation; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Structure, Tertiary; Pyrimidines; src-Family Kinases; Time Factors; Transfection; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Antibodies, Monoclonal; Blotting, Western; Collagen; Crotalid Venoms; Cytosol; Enzyme Precursors; Flow Cytometry; Guanine Nucleotide Exchange Factors; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Membrane Proteins; Mice; Mice, Knockout; Peptide Fragments; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-vav; Pyrimidines; Receptors, Gastrointestinal Hormone; Receptors, Immunologic; Receptors, Neuropeptide Y; Receptors, Thrombin; Signal Transduction; Syk Kinase; Tyrosine; Viper Venoms

Topics: Animals; Chorionic Gonadotropin; Enzyme Inhibitors; Focal Adhesion Kinase 1; GTP-Binding Proteins; Humans; Leydig Cell Tumor; Male; Mice; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Pyrimidines; Receptors, LH; Recombinant Proteins; Signal Transduction; src-Family Kinases; Testicular Neoplasms; Tumor Cells, Cultured; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Cells, Cultured; Cytokines; DNA-Binding Proteins; Mast Cells; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Pyrimidines; RNA-Binding Proteins; Tyrosine

Topics: Androstadienes; Apyrase; Blood Platelets; Collagen; Humans; Integrin alpha2beta1; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Pyrimidines; rap1 GTP-Binding Proteins; Tyrosine; Wortmannin

Topics: Androstadienes; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanosine Triphosphate; Humans; Immunoblotting; Immunoprecipitation; Infrared Rays; Intracellular Signaling Peptides and Proteins; Kinetics; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; Radiation, Ionizing; Signal Transduction; src-Family Kinases; Temperature; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Wortmannin; X-Rays

Topics: Actins; Animals; Benzamides; Biological Transport, Active; Cell Line; Humans; Imatinib Mesylate; Phosphorylation; Piperazines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Pyrimidines; Signal Transduction; src-Family Kinases; Tyrosine; Vaccinia virus; Viral Structural Proteins

Topics: Animals; Cell Line; Cell Line, Transformed; Cell Transformation, Viral; Coatomer Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Glyceraldehyde-3-Phosphate Dehydrogenases; Golgi Apparatus; Histidine; Humans; Isoenzymes; Kidney; Luminescent Measurements; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Pyrimidines; rab2 GTP-Binding Protein; Rats; Recombinant Proteins; src-Family Kinases; Tyrosine

Topics: Actin Cytoskeleton; Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antigens, CD; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Chloroquine; CpG Islands; Cytokines; Cytoskeleton; Dendritic Cells; Humans; I-kappa B Proteins; Interferon-alpha; Interleukin-6; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Knockout; Models, Biological; Monocytes; Myeloid Differentiation Factor 88; NF-KappaB Inhibitor alpha; Oligodeoxyribonucleotides; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-hck; Pyrazoles; Pyrimidines; Quinacrine; RNA, Small Interfering; src-Family Kinases; Syk Kinase; Toll-Like Receptor 9; Tyrosine; Wortmannin

Topics: Animals; Antibodies; Base Sequence; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression; GTP-Binding Protein beta Subunits; Heparin-binding EGF-like Growth Factor; Insulin-Secreting Cells; Intercellular Signaling Peptides and Proteins; Models, Biological; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Pyrimidines; Receptors, Thyrotropin-Releasing Hormone; Signal Transduction; src-Family Kinases; Thyrotropin-Releasing Hormone; Tyrosine

Topics: Animals; Apoptosis; Cell Line; Cycloheximide; Eflornithine; Enzyme Activation; Fibronectins; Integrin beta3; Intestinal Mucosa; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; src-Family Kinases; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Tyrosine

Topics: Adherens Junctions; Animals; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Culture Media, Conditioned; Down-Regulation; ErbB Receptors; Humans; Interleukins; Liver Neoplasms; Macrophage Activation; Macrophages, Peritoneal; Mice; Neoplasm Invasiveness; Phosphorylation; Pyrimidines; src-Family Kinases; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Antibodies, Monoclonal; Antigens, Ly; Cell Line; Cells, Cultured; Cross-Linking Reagents; Cytotoxicity Tests, Immunologic; Down-Regulation; Humans; Intracellular Signaling Peptides and Proteins; Killer Cells, Natural; Lectins, C-Type; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred C57BL; Mice, Knockout; NK Cell Lectin-Like Receptor Subfamily A; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Pyrimidines; Receptors, NK Cell Lectin-Like; Signal Transduction; src-Family Kinases; Syk Kinase; Tyrosine

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Amides; Apyrase; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Humans; Integrin alpha2; Intracellular Signaling Peptides and Proteins; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Purinergic P2; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Signal Transduction; Tyrosine

Topics: Animals; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Focal Adhesion Kinase 2; Hydrogen Peroxide; Immunoblotting; Insulin-Like Growth Factor I; Models, Biological; Muscle, Smooth, Vascular; Oxidants; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Receptor, IGF Type 1; src-Family Kinases; Tyrosine; Tyrphostins

Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Mice; Mice, Knockout; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Pyrimidines; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, trkB; Receptors, Cell Surface; RNA, Small Interfering; Signal Transduction; Time Factors; Transfection; Tyrosine

Topics: Androgens; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Dihydrotestosterone; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Indoles; Interleukin-6; Kinetics; Male; Mice; Mice, SCID; Neuregulin-1; Phosphorylation; Prostatic Neoplasms; Pyrimidines; Receptors, Androgen; src-Family Kinases; Sulfonamides; Tyrosine; Xenograft Model Antitumor Assays

Topics: Actin Cytoskeleton; Actins; Cell Adhesion; Cell Movement; Cells, Cultured; Cortactin; Cytoskeleton; Endothelial Cells; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Neutrophils; Phosphorylation; Pyrimidines; RNA, Small Interfering; src-Family Kinases; Tyrosine

Topics: Animals; C-Reactive Protein; Cell Adhesion Molecules; Cell Membrane; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pseudopodia; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Proteinase-Activated; Signal Transduction; src-Family Kinases; Syk Kinase; Thrombin; Tyrosine

Topics: Animals; Breast Neoplasms; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Female; Fibroblasts; Humans; Mice; Multiprotein Complexes; Neuregulin-1; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; src-Family Kinases; Tyrosine

Topics: Cell Line; Cell Proliferation; Epithelial Cells; Flavonoids; Focal Adhesion Kinase 1; Humans; Lung; Mechanotransduction, Cellular; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; RNA Interference; RNA, Small Interfering; src-Family Kinases; Stress, Mechanical; Time Factors; Transfection; Tyrosine

Topics: Actins; Animals; Caco-2 Cells; Cell Membrane; Cell Movement; Dogs; Epidermal Growth Factor; Epithelial Cells; Estrenes; Fluorescence Resonance Energy Transfer; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Mice; Microfilament Proteins; Mutation; Phospholipase C gamma; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Pyrrolidinones; RNA, Small Interfering; Signal Transduction; src Homology Domains; src-Family Kinases; Transfection; Tyrosine; Wound Healing

Topics: Amino Acid Motifs; Amino Acid Sequence; Anaplasma phagocytophilum; Animals; Bacterial Proteins; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Genistein; HL-60 Cells; Humans; Immunoblotting; Immunoprecipitation; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyrimidines; Time Factors; Tyrosine

Topics: Apoptosis; Calcium Signaling; Cell Survival; Genistein; Humans; Hydrogen Peroxide; Immunoprecipitation; Necrosis; Oxidative Stress; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Pyrimidines; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; TRPM Cation Channels; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells

Topics: Actins; Amino Acid Substitution; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caco-2 Cells; Cell Survival; Cytochalasins; Cytoplasm; Fibroblasts; Focal Adhesion Kinase 1; Humans; Indoles; Mutation, Missense; Osmotic Pressure; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrimidines; Signal Transduction; src-Family Kinases; Sulfonamides; Thiazolidines; Tyrosine

Topics: Animals; Blotting, Western; Brain Ischemia; Cell Death; Cell Survival; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Hippocampus; Immunoprecipitation; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Neuroprotective Agents; Phosphorylation; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; src-Family Kinases; Tyrosine

Topics: Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Gefitinib; Humans; Immunoprecipitation; Lung Neoplasms; Phosphorylation; Point Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Quinazolines; Sequence Deletion; Tyrosine

Topics: Animals; Apoptosis; Cell Survival; Cycloheximide; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibronectins; Integrin beta3; Intestinal Mucosa; MAP Kinase Kinase Kinases; Mice; Mutation; Oligopeptides; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Protein Kinase Inhibitors; Putrescine; Pyrimidines; Quinazolines; Rats; Signal Transduction; src-Family Kinases; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

Topics: Animals; Cell Line; Cyclic Nucleotide-Gated Cation Channels; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channel Gating; Kinetics; Membrane Potentials; Mice; Muscle Proteins; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Point Mutation; Potassium Channels; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Transfection; Tyrosine

Topics: Active Transport, Cell Nucleus; Animals; Cell Line; Cell Nucleus; Chlorocebus aethiops; DNA-Binding Proteins; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; Phosphorylation; Protein Binding; Pyrimidines; Signal Transduction; Transcriptional Activation; Tyrosine

Topics: Animals; Cells, Cultured; Cerebellum; Chromones; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Purkinje Cells; Pyrimidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; src-Family Kinases; Transfection; Tyrosine

Topics: Animals; Brain Ischemia; Cytoprotection; Dizocilpine Maleate; Hippocampus; Male; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neuroprotective Agents; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; src-Family Kinases; Tyrosine

Topics: Cell Cycle Proteins; Cell Line, Tumor; Humans; Nijmegen Breakage Syndrome; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Movement; CSK Tyrosine-Protein Kinase; Dogs; Focal Adhesions; Humans; Mice; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-crk; Pyrimidines; src Homology Domains; src-Family Kinases; Tyrosine

Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Computer Simulation; HeLa Cells; Humans; Hydrogen Peroxide; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myocardium; Nucleotide Transport Proteins; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Stability; Protein Structure, Tertiary; Pyrimidines; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; src-Family Kinases; Structure-Activity Relationship; Transfection; Tyrosine; Vanadates

Topics: Animals; Ephrin-B2; Female; Hyperalgesia; Pelvis; Phosphorylation; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; src-Family Kinases; Tyrosine; Urethra

Topics: Animals; Apoptosis; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunoprecipitation; Indoles; Isoflavones; Neurons; Nimodipine; Phosphorylation; Potassium Chloride; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Time Factors; Tyrosine

Topics: Adolescent; Adult; Amino Acid Motifs; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium Signaling; CD4-Positive T-Lymphocytes; CD40 Ligand; Humans; Hydrogen Peroxide; Jurkat Cells; Lectins, C-Type; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Middle Aged; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Receptors, Antigen, T-Cell; Tyrosine; Young Adult

Topics: Animals; Brain; Cell Line, Tumor; Humans; Mice; Mice, Transgenic; Neurons; Phosphorylation; Protein Phosphatase 2; Pyrimidines; Rats; Rats, Sprague-Dawley; src-Family Kinases; tau Proteins; Tauopathies; Trace Elements; Tyrosine; Zinc

Topics: Animals; Benzoquinones; Cattle; Cells, Cultured; Endothelial Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; RNA, Small Interfering; Signal Transduction; Tyrosine

Topics: Actins; Adherens Junctions; Anthracenes; Caco-2 Cells; Enzyme Activation; Genes, src; Humans; Mechanics; Mitogen-Activated Protein Kinase 9; Myosin-Light-Chain Kinase; Periodicity; Phosphorylation; Pyrimidines; Tight Junctions; Tyrosine

Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Caveolin 1; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydrogen Peroxide; Insulin-Secreting Cells; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microscopy, Confocal; Oxidants; Palmitates; Phosphorylation; Pyrimidines; Reactive Oxygen Species; Sphingosine; src-Family Kinases; Tyrosine

Topics: Actin Depolymerizing Factors; Animals; Annexin A2; Antibodies; Blood-Brain Barrier; Brain; Chelating Agents; Cryptococcus neoformans; Egtazic Acid; Endothelial Cells; Gene Expression Regulation, Fungal; Mice; Mutation; Phosphorylation; Pyrimidines; RNA, Small Interfering; S100 Proteins; Time Factors; Transcytosis; Tyrosine

Topics: Animals; Caco-2 Cells; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Intestinal Mucosa; Leupeptins; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Stability; Protein Tyrosine Phosphatases; Proteolysis; Pyrimidines; src-Family Kinases; Symporters; Tyrosine; Vanadates

Topics: Animals; Biological Transport; Cold Temperature; Ganglia, Spinal; HEK293 Cells; Humans; Inflammation; Neoplasms; Neurons, Afferent; Pain; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Rats; src-Family Kinases; TRPM Cation Channels; Tyrosine

Topics: Animals; Caveolin 1; Cell Line, Tumor; Cell Movement; Cell Survival; Dasatinib; Female; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neuropeptides; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; rac1 GTP-Binding Protein; Skin Neoplasms; src-Family Kinases; Transfection; Tyrosine