Compounds > ag 112
Page last updated: 2024-09-05

ag 112 and indirubin-3'-monoxime

ag 112 has been researched along with indirubin-3'-monoxime in 3 studies

Compound Research Comparison

Studies
(ag 112)		Trials
(ag 112)		Recent Studies (post-2010)
(ag 112)		Studies
(indirubin-3'-monoxime)		Trials
(indirubin-3'-monoxime)		Recent Studies (post-2010) (indirubin-3'-monoxime)
19010139082

Protein Interaction Comparison

ProteinTaxonomyag 112 (IC50)indirubin-3'-monoxime (IC50)
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Glycogen synthase kinase-3 beta Sus scrofa (pig)0.022
[Tau protein] kinase Sus scrofa (pig)0.022
Serine/threonine-protein kinase Sgk1Homo sapiens (human)0.38
Aurora kinase AHomo sapiens (human)4
Cyclin-T1Homo sapiens (human)2.4
Serine/threonine-protein kinase 17BHomo sapiens (human)0.71
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.099
Tyrosine-protein kinase LckHomo sapiens (human)0.3
Cyclin-dependent kinase 1Homo sapiens (human)0.126
Insulin-like growth factor 1 receptorHomo sapiens (human)5.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)8.2
Fibroblast growth factor receptor 1Homo sapiens (human)2.5
Cyclin-dependent kinase 4Homo sapiens (human)3.33
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.099
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)0.1
Cyclin-A2Homo sapiens (human)0.515
G1/S-specific cyclin-D1Homo sapiens (human)3.33
G1/S-specific cyclin-E1Homo sapiens (human)0.7
Cyclin-dependent kinase 2Homo sapiens (human)0.5767
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0785
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.022
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0599
Cyclin-dependent kinase 9Homo sapiens (human)2.4
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.1
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.1
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.099
Aurora kinase BHomo sapiens (human)2.3
Aurora kinase CHomo sapiens (human)0.3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1

Other Studies

3 other study(ies) available for ag 112 and indirubin-3'-monoxime

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013