Compounds > aflatoxin b1
Page last updated: 2024-08-21

aflatoxin b1 and ketoconazole

aflatoxin b1 has been researched along with ketoconazole in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fink-Gremmels, J; Kuilman, ME; Maas, RF1
Jeong, S; Kang, BK; Kim, BR; Kim, DH; Kim, KS; Kim, NY; Kim, YC; Kwon, KB; Park, R; Ryu, DG1
Stewart, JK; Tombes, RM; Zhang, L; Zhou, Q; Zuniga, MA1
Darnell, M; Edebert, I; Ek, M; Ingelman-Sundberg, M; Neve, EP; Sivertsson, L1

Other Studies

6 other study(ies) available for aflatoxin b1 and ketoconazole

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Cytochrome P450-mediated metabolism and cytotoxicity of aflatoxin B(1) in bovine hepatocytes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2000, Volume: 14, Issue:4

    Topics: Aflatoxin B1; Aflatoxin M1; Animals; Benzoflavones; Biotransformation; Cattle; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ketoconazole; Liver; Steroid Hydroxylases

2000
Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes.
    Planta medica, 2001, Volume: 67, Issue:5

    Topics: Aflatoxin B1; Animals; Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flavonoids; Humans; Hydroxytestosterones; Ketoconazole; Lamiaceae; Microsomes, Liver; Plant Extracts; Plant Roots; Rats

2001
Mixed inhibition of P450 3A4 as a chemoprotective mechanism against aflatoxin B1-induced cytotoxicity with cis-terpenones.
    Chemical research in toxicology, 2008, Volume: 21, Issue:3

    Topics: Aflatoxin B1; Algorithms; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Glutathione; Humans; Hydrolysis; In Vitro Techniques; Indicators and Reagents; Ketoconazole; Kinetics; Microsomes, Liver; Phenanthrenes

2008
CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:6

    Topics: Aflatoxin B1; Catalysis; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Gene Expression; Humans; Ketoconazole; Microsomes, Liver; Midazolam; Rifampin; Testosterone; Transcription Factors

2010