aflatoxin b1 has been researched along with guanine in 62 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (30.65) | 18.7374 |
1990's | 21 (33.87) | 18.2507 |
2000's | 12 (19.35) | 29.6817 |
2010's | 8 (12.90) | 24.3611 |
2020's | 2 (3.23) | 2.80 |
Authors | Studies |
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Taylor, ER | 1 |
Donahue, PR; Groopman, JD; Hasler, JA; Pikul, A; Trudel, LJ; Wogan, GN | 1 |
DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A | 1 |
Garner, RC; Harrison, JC | 1 |
Said, B; Shank, RC | 1 |
Johnson, RL; Shaulsky, G; Shockcor, JP; Stark, AA; Taylor, LC | 1 |
Bonnett, M; Taylor, ER | 1 |
Benasutti, M; Ejadi, S; Loechler, EL; Whitlow, MD | 1 |
Davidson, NE; Egner, PA; Groopman, JD; Kensler, TW; Pikul, A; Roebuck, BD | 1 |
Autrup, H; Seremet, T; Wakhisi, J; Wasunna, A | 1 |
Hsieh, DP | 1 |
Conley, MP; Humayun, MZ; Jacobsen, JS; Refolo, LM; Sambamurti, K | 1 |
Garner, RC; Smith, JR; Wood, ML | 1 |
Loechler, EL; Teeter, MM; Whitlow, MD | 1 |
Autrup, H; Harris, CC; Vahakangas, K; Wakhisi, J; Wasunna, A | 1 |
Kuwahara, J; Sugiura, Y; Suzuki, T | 1 |
Chetsanga, CJ; Frenette, GP | 1 |
Autrup, H; Bradley, KA; Shamsuddin, AK; Wakhisi, J; Wasunna, A | 1 |
Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA | 1 |
Den Engelse, L; Kriek, E; Scherer, E; Westra, JG | 1 |
Bennett, RA; Essigmann, JM; Wogan, GN | 1 |
Chu, YH; Craig, AW; O'Connor, PJ | 1 |
Croy, RG; Groopman, JD; Wogan, GN | 1 |
Chu, FS; Li, YK; Pestka, JJ | 1 |
Chu, YH; Margison, GP; Maru, GB; O'Connor, PJ | 1 |
Johnston, DS; Stone, MP | 2 |
Groopman, JD; Weaver, VM | 1 |
Groopman, JD; Hasler, J; Junshi, C; Kensler, TW; Wild, CP; Wogan, GN | 1 |
Judah, DJ; Neal, GE; Olubuyide, IO; Riley, J; Seawright, AA; Snowden, RT | 1 |
Groopman, JD; Grossman, L; Lim, SE; Mayernik, JA; Oleykowski, CA; Wogan, GN; Yeung, AT | 1 |
Bailey, EA; Essigmann, JM; Harris, TM; Iyer, RS; Stone, MP | 1 |
Chen, CJ; Liaw, YF; Lien, JP; Yu, MW | 1 |
Groopman, JD; Kensler, TW | 1 |
Groopman, JD; Kamataki, T; Katsuki, M; Li, Y; Wang, JS; Yokoi, T | 1 |
Chen, CJ; Chiang, YC; Lien, JP; Yu, MW | 1 |
Sashidhar, RB; Sujatha, N; Vidyasagar, T | 2 |
Campbell, TC; Lange, T; Root, M | 1 |
Essigmann, JM; Kobertz, WR; Marzilli, LA; Vouros, P; Wang, D | 1 |
Mathison, BH; Ross, MK; Said, B; Shank, RC | 1 |
Ross, MK; Said, B; Shank, RC | 1 |
Bhat, RV; Nayak, S; Sashidhar, RB | 1 |
Bailey, GS; Egner, PA; Gange, SJ; Groopman, JD; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Qian, GS; Wang, JB; Wu, Y; Zhang, BC; Zhang, QN; Zhu, YR | 1 |
Essigmann, JM; Hamm, ML; Harris, CM; Harris, TM; Henderson, PT; Smela, ME | 1 |
Giri, I; Stone, MP | 1 |
Egner, PA; Groopman, JD; Johnson, JK; Kensler, TW; Nathasingh, CK; Roebuck, BD; Yu, X | 1 |
El-Nezami, H; Juvonen, RO; Kemiläinen, H; Ling, W; Ma, J; Mykkänen, H; Mykkänen, O; Polychronaki, N; Salminen, E; Salminen, S; Zhu, H | 1 |
Alessi, M; Bedard, LL; Davey, S; Massey, TE | 1 |
El-Nezami, HS; Juvonen, RO; Ling, W; Ma, J; Mykkänen, HM; Polychronaki, NN; Poussa, T; Salminen, EK; Salminen, SJ; Zhu, H | 1 |
Egner, PA; Friesen, MD; Groopman, JD; Kensler, TW; Wang, JS | 1 |
Bren, U; Guengerich, FP; Mavri, J | 1 |
Nayak, S; Sashidhar, RB | 1 |
Banitaba, MH; Davarani, SS; Mehdinia, A | 1 |
Croy, RG; Egner, PA; Essigmann, JM; Fiala, JL; Groopman, JD; Kensler, KH; Ruchirawat, M; Wiriyachan, N; Wogan, GN | 1 |
Belanger, CL; Bouhenguel, JT; Croy, RG; Egner, PA; Essigmann, JM; Groopman, JD; Trudel, LJ; Wattanawaraporn, R; Wogan, GN; Woo, LL | 1 |
Asim, M; Kar, P; Sarma, MP; Thayumanavan, L | 1 |
Baptista, GZ; Jager, AV; Oliveira, CA; Souto, PC; Tonin, FG | 1 |
Chawanthayatham, S; Croy, RG; Egner, PA; Essigmann, JM; Fedeles, BI; Groopman, JD; Satayavivad, J; Slocum, SL; Sriwattanapong, K | 1 |
He, L; Li, D; Liu, L; Liu, W; Shu, W; Tan, Y; Wang, J; Wang, L; Zhao, X; Zheng, C | 1 |
Kellum, AH; Lloyd, RS; McCullough, AK; Minko, IG; Stone, MP; Tomar, R; Voehler, MW | 1 |
Apolinário, LA; Augusto, MJ; Jager, AV; Khaneghah, AM; Moosavi, MH; Oliveira, CAF; Petta, T; Ramalho, FS; Ramalho, LNZ; Trotta, MR | 1 |
5 review(s) available for aflatoxin b1 and guanine
Article | Year |
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The structure of the aflatoxin B1-DNA adduct at N7 of guanine. Theoretical intercalation and covalent adduct models.
Topics: Aflatoxin B1; Aflatoxins; DNA; Guanine; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation | 1989 |
Genotoxicity of mycotoxins.
Topics: Aflatoxin B1; Aflatoxins; Animals; Binding Sites; DNA; Guanine; Mutagenicity Tests; Mycotoxins | 1986 |
Enhanced repair of O6-alkylguanine in mammalian tissues.
Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity | 1984 |
Formation of DNA modifications by chemical carcinogens. Identification, localization and quantification.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies; Antibodies, Monoclonal; Benzo(a)pyrene; Blood-Brain Barrier; Blood-Testis Barrier; Carcinogens; Cyclophosphamide; DNA; DNA, Single-Stranded; Ethylnitrosourea; Female; Guanine; Histocytochemistry; Humans; Liver; Male; Nucleic Acid Conformation; Respiratory System; Spectrometry, Fluorescence; Tissue Distribution | 1984 |
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials.
Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes | 1996 |
2 trial(s) available for aflatoxin b1 and guanine
Article | Year |
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Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer.
Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Animals; Biomarkers; Carcinoma, Hepatocellular; China; Chlorophyllides; DNA Adducts; Female; Food Contamination; Guanine; Humans; Liver Neoplasms; Male; Middle Aged; Risk Factors | 2001 |
Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China.
Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; China; DNA Adducts; Double-Blind Method; Guanine; Humans; Lacticaseibacillus rhamnosus; Liver Neoplasms; Placebos; Probiotics; Propionibacterium; Risk Factors | 2006 |
55 other study(ies) available for aflatoxin b1 and guanine
Article | Year |
---|---|
Aflatoxin B1 and DNA adducts. Proposed model for surface noncovalent and covalent complexes with N(7) of guanine. II.
Topics: Aflatoxin B1; Base Sequence; Binding Sites; DNA; DNA Adducts; Guanine; Molecular Conformation; X-Ray Diffraction | 1992 |
Molecular dosimetry in rat urine of aflatoxin-N7-guanine and other aflatoxin metabolites by multiple monoclonal antibody affinity chromatography and immunoaffinity/high performance liquid chromatography.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antibody Affinity; Chromatography, Affinity; Chromatography, High Pressure Liquid; Guanine; Rats; Regression Analysis | 1992 |
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes | 1992 |
Immunological and HPLC detection of aflatoxin adducts in human tissues after an acute poisoning incident in S.E. Asia.
Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Asia, Southeastern; Carcinogens; Child; Chromatography, High Pressure Liquid; DNA; Enzyme-Linked Immunosorbent Assay; Female; Guanine; Humans; Kidney; Liver; Lung; Male; Middle Aged; Poisoning | 1991 |
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids | 1991 |
Properties of aflatoxin-DNA adducts formed by photoactivation and characterization of the major photoadduct as aflatoxin-N7-guanine.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes; Photochemistry; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 1990 |
Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences.
Topics: Aflatoxin B1; Aflatoxins; Base Sequence; DNA; DNA Restriction Enzymes; Guanine; Polydeoxyribonucleotides; Protein Binding; Structure-Activity Relationship | 1988 |
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Enzyme Induction; Ethoxyquin; gamma-Glutamyltransferase; Glutathione Transferase; Guanine; Liver; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344 | 1986 |
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; DNA Damage; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Kenya; Liver Neoplasms; Male; Sex Factors | 1987 |
DNA replication-blocking properties of adducts formed by aflatoxin B1-2,3-dichloride and aflatoxin B1-2,3-oxide.
Topics: Aflatoxin B1; Aflatoxins; Base Composition; DNA; DNA Damage; DNA Replication; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Guanine; Magnesium; Manganese; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid | 1987 |
Structural characterization of the major adducts obtained after reaction of an ultimate carcinogen aflatoxin B1-dichloride with calf thymus DNA in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Thymus Gland | 1988 |
Mapping the binding site of aflatoxin B1 in DNA: molecular modeling of the binding sites for the N(7)-guanine adduct of aflatoxin B1 in different DNA sequences.
Topics: Aflatoxin B1; Aflatoxins; Base Sequence; Binding Sites; DNA; Guanine; Intercalating Agents; Models, Molecular | 1988 |
Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.
Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Age Factors; Child; Environmental Exposure; Female; Geography; Guanine; Humans; Kenya; Male; Middle Aged; Sex Factors | 1985 |
Nucleotide sequence cleavage of guanine-modified DNA with aflatoxin B1, dimethyl sulfate, and mitomycin C by bleomycin and deoxyribonuclease I.
Topics: Aflatoxin B1; Aflatoxins; Base Sequence; Bleomycin; Chemical Phenomena; Chemistry; Deoxyribonuclease I; DNA; Endodeoxyribonucleases; Guanine; Mitomycin; Mitomycins; Sulfuric Acid Esters; Sulfuric Acids | 1983 |
Excision of aflatoxin B1-imidazole ring opened guanine adducts from DNA by formamidopyrimidine-DNA glycosylase.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; DNA; DNA-Formamidopyrimidine Glycosylase; Escherichia coli Proteins; Guanine; Imidazoles; Kinetics; Liver; N-Glycosyl Hydrolases; Rats; Rats, Inbred F344 | 1983 |
Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya.
Topics: Aflatoxin B1; Aflatoxins; Biotransformation; Guanine; Humans; Kenya; Spectrometry, Fluorescence | 1983 |
Excretion of an aflatoxin-guanine adduct in the urine of aflatoxin B1-treated rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guanine; Rats | 1981 |
Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.
Topics: Adenine; Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Rats; Stimulation, Chemical | 1981 |
In vitro reactions of aflatoxin B1-adducted DNA.
Topics: Aflatoxin B1; Aflatoxins; Apurinic Acid; Chemical Phenomena; Chemistry; DNA; Guanine; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation | 1981 |
Reactivity of aflatoxin B2a antibody with aflatoxin B1-modified DNA and related metabolites.
Topics: Aflatoxin B1; Aflatoxins; Antibodies; Antibody Specificity; Cross Reactions; DNA; Enzyme-Linked Immunosorbent Assay; Guanine | 1982 |
Effects of carcinogens and partial hepatectomy upon the hepatic O6-methylguanine repair system in mice.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell-Free System; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Hepatectomy; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rats; Rats, Inbred Strains | 1982 |
Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR.
Topics: Aflatoxin B1; Base Sequence; Dinucleoside Phosphates; DNA; DNA Adducts; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons; Solutions | 1995 |
Fluorescence quantification of aflatoxin N7-guanine adducts.
Topics: Aflatoxin B1; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Hydrolysis; Male; Rats; Rats, Inbred F344; Spectrometry, X-Ray Emission | 1994 |
Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.
Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Animals; Biomarkers; China; DNA; DNA Adducts; DNA Damage; Female; Gambia; Guanine; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Rats, Inbred F344 | 1993 |
A comparison of the effects of aflatoxin B1 on the livers of rats and duck hepatitis B virus-infected and noninfected ducks.
Topics: Aflatoxin B1; Animals; Blotting, Southern; Chromatography, High Pressure Liquid; DNA; Ducks; Guanine; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Weight Gain | 1993 |
Repair of aflatoxin B1 DNA adducts by the UvrABC endonuclease of Escherichia coli.
Topics: Aflatoxin B1; Base Sequence; DNA Damage; DNA Repair; DNA, Superhelical; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Guanine; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Substrate Specificity | 1993 |
Mutational properties of the primary aflatoxin B1-DNA adduct.
Topics: Aflatoxin B1; Bacteriophage M13; Base Sequence; Carcinoma, Hepatocellular; DNA Adducts; DNA, Viral; Escherichia coli; Guanine; Humans; Liver Neoplasms; Models, Molecular; Molecular Sequence Data; Mutagenesis; SOS Response, Genetics; Structure-Activity Relationship | 1996 |
Effects of multiple risk factors for hepatocellular carcinoma on formation of aflatoxin B1-DNA adducts.
Topics: Aflatoxin B1; Age Factors; Alcohol Drinking; Biomarkers; Carcinogens; Carcinoma, Hepatocellular; Carrier State; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Logistic Models; Male; Multivariate Analysis; Prospective Studies; Risk Factors; Smoking; Taiwan | 1996 |
In vivo activation of aflatoxin B1 in C57BL/6N mice carrying a human fetus-specific CYP3A7 gene.
Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; DNA; DNA Damage; Fetus; Guanine; Humans; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic | 1997 |
Plasma antioxidant vitamins, chronic hepatitis B virus infection and urinary aflatoxin B1-DNA adducts in healthy males.
Topics: Adult; Aflatoxin B1; Aged; Antioxidants; beta Carotene; Carotenoids; Chronic Disease; DNA; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Testosterone; Vitamin E; Vitamins | 1997 |
Determination of aflatoxin B1-DNA adduct in rat liver by enzyme immunoassay.
Topics: Aflatoxin B1; Animals; Antigens; Carcinogens; Cattle; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Guanine; Liver; Male; Rabbits; Rats; Rats, Inbred F344; Serum Albumin, Bovine | 1997 |
Direct synthesis of aflatoxin B1-N7 guanine adduct: a reference standard for biological monitoring of dietary aflatoxin exposure in molecular epidemiological studies.
Topics: Aflatoxin B1; Chlorobenzoates; Chromatography, High Pressure Liquid; Food Analysis; Guanine; Reference Standards | 1997 |
Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver.
Topics: Administration, Oral; Aflatoxin B1; Animals; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Mass spectral identification and positional mapping of aflatoxin B1-guanine adducts in oligonucleotides.
Topics: Aflatoxin B1; Carcinogens; DNA Adducts; Guanine; Indicators and Reagents; Mass Spectrometry; Oligonucleotides | 1998 |
5-Methylcytosine in CpG sites and the reactivity of nearest neighboring guanines toward the carcinogen aflatoxin B1-8,9-epoxide.
Topics: 5-Methylcytosine; Aflatoxin B1; Carcinogens; Cytosine; Gene Expression Regulation, Neoplastic; Genes, p53; Guanine; Humans; Oligonucleotides | 1999 |
DNA-damaging effects of genotoxins in mixture: modulation of covalent binding to DNA.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Binding, Competitive; Cattle; DNA; DNA Adducts; DNA Damage; Guanine; Mutagens; Sulfuric Acid Esters | 2000 |
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I.
Topics: Aflatoxin B1; DNA; DNA Adducts; DNA Polymerase I; DNA Replication; Exonucleases; Guanine; Oligonucleotides; Templates, Genetic | 2000 |
Quantification and validation of enzyme immunoassay for urinary aflatoxin B1-N7-guanine adduct for biological monitoring of aflatoxins.
Topics: Aflatoxin B1; Aflatoxins; Animals; DNA Adducts; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Female; Food Contamination; Guanine; Humans; Male; Rabbits; Rats; Rats, Inbred F344 | 2001 |
The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.
Topics: Aflatoxin B1; Bacteriophage M13; Carcinoma, Hepatocellular; DNA Adducts; DNA, Neoplasm; DNA, Viral; Guanine; Humans; Liver Neoplasms; Molecular Structure; Mutagenesis; Mutagens; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
Wobble dC.dA pairing 5' to the cationic guanine N7 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 adduct: implications for nontargeted AFB1 mutagenesis.
Topics: Aflatoxin B1; Base Composition; Base Pair Mismatch; Base Sequence; Cations; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Protons; Structure-Activity Relationship | 2003 |
Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B1.
Topics: Administration, Oral; Aflatoxin B1; Aflatoxin M1; Animals; Chromatography, Liquid; DNA Adducts; DNA Damage; Guanine; Hydroxylation; Liver; Male; Mass Spectrometry; Microsomes, Liver; Models, Animal; Rats; Rats, Inbred F344; Tupaiidae | 2003 |
Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; China; Feces; Guanine; Hepatitis B; Humans; Male | 2005 |
Susceptibility to aflatoxin B1-induced carcinogenesis correlates with tissue-specific differences in DNA repair activity in mouse and in rat.
Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; DNA; DNA Repair; Female; Genetic Predisposition to Disease; Guanine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Mice; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity | 2005 |
Quantification of aflatoxin-B1-N7-Guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry.
Topics: Aflatoxin B1; Chromatography, High Pressure Liquid; Guanine; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Guanine alkylation by the potent carcinogen aflatoxin B1: quantum chemical calculations.
Topics: Aflatoxin B1; Algorithms; Alkylation; Carcinogens; DNA; Energy Transfer; Epoxy Compounds; Guanine; Kinetics; Models, Molecular; Quantum Theory | 2007 |
Metabolic intervention of aflatoxin B1 toxicity by curcumin.
Topics: Aflatoxin B1; Albumins; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcuma; Curcumin; Dietary Supplements; DNA Adducts; Enzymes; Guanine; Inactivation, Metabolic; Liver; Male; Phytotherapy; Plant Extracts; Rats | 2010 |
Study of interactions between DNA and aflatoxin B1 using electrochemical and fluorescence methods.
Topics: Aflatoxin B1; Biosensing Techniques; Carbon; DNA; Electrochemical Techniques; Electrodes; Guanine; Ionic Liquids; Pyridinium Compounds; Spectrometry, Fluorescence | 2011 |
Sulforaphane-mediated reduction of aflatoxin B₁-N⁷-guanine in rat liver DNA: impacts of strain and sex.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; Dose-Response Relationship, Drug; Female; Guanine; Isothiocyanates; Liver; Male; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Sulfoxides; Thiocyanates | 2011 |
Aflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice.
Topics: Aflatoxin B1; Age Factors; Animals; Animals, Newborn; Base Sequence; Carcinogenicity Tests; Carcinoma, Hepatocellular; DNA Adducts; Female; Guanine; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutagens; Mutation Rate; Sequence Analysis, DNA; Sex Factors | 2011 |
Role of aflatoxin B1 as a risk for primary liver cancer in north Indian population.
Topics: Adult; Aflatoxin B1; Alcohol Drinking; Carcinoma, Hepatocellular; Case-Control Studies; Chronic Disease; Female; Food Analysis; Food Microbiology; Guanine; Hepatitis B; Hepatitis C; Humans; India; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Risk Factors | 2011 |
Assessment of aflatoxin exposure using serum and urinary biomarkers in São Paulo, Brazil: A pilot study.
Topics: Adult; Aflatoxin B1; Aflatoxin M1; Arachis; Biomarkers; Brazil; Dairy Products; Diet; Environmental Monitoring; Food Contamination; Guanine; Humans; Lysine; Middle Aged; Pilot Projects; Zea mays | 2016 |
Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.
Topics: Activation, Metabolic; Aflatoxin B1; Animals; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; DNA Adducts; DNA Damage; Female; Gestational Age; Glutathione Transferase; Guanine; Hepatocytes; Isoenzymes; Liver; Maternal Exposure; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy | 2017 |
Microcystin-LR increases genotoxicity induced by aflatoxin B1 through oxidative stress and DNA base excision repair genes in human hepatic cell lines.
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Catalase; Comet Assay; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glutathione; Guanine; Hepatocytes; Humans; Liver Neoplasms; Marine Toxins; Microcystins; Oxidative Stress; Superoxide Dismutase; Toxicity Tests | 2018 |
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B
Topics: Aflatoxin B1; Base Sequence; Biocatalysis; DNA; DNA Adducts; DNA Glycosylases; Guanine; Humans; Molecular Structure; Pyrimidines | 2021 |
Oncogenic and tumor suppressor pathways in subchronic aflatoxicosis in rats: Association with serum and urinary aflatoxin exposure biomarkers.
Topics: Aflatoxin B1; Aflatoxin M1; Alanine Transaminase; Animals; Aspartate Aminotransferases; beta Catenin; Biomarkers; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Gene Expression; Guanine; Hepatocytes; Liver; Lysine; Male; Precancerous Conditions; Rats, Wistar; Retinoblastoma Protein | 2021 |