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aflatoxin b1 and guanine

aflatoxin b1 has been researched along with guanine in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199019 (30.65)18.7374
1990's21 (33.87)18.2507
2000's12 (19.35)29.6817
2010's8 (12.90)24.3611
2020's2 (3.23)2.80

Authors

AuthorsStudies
Taylor, ER1
Donahue, PR; Groopman, JD; Hasler, JA; Pikul, A; Trudel, LJ; Wogan, GN1
DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A1
Garner, RC; Harrison, JC1
Said, B; Shank, RC1
Johnson, RL; Shaulsky, G; Shockcor, JP; Stark, AA; Taylor, LC1
Bonnett, M; Taylor, ER1
Benasutti, M; Ejadi, S; Loechler, EL; Whitlow, MD1
Davidson, NE; Egner, PA; Groopman, JD; Kensler, TW; Pikul, A; Roebuck, BD1
Autrup, H; Seremet, T; Wakhisi, J; Wasunna, A1
Hsieh, DP1
Conley, MP; Humayun, MZ; Jacobsen, JS; Refolo, LM; Sambamurti, K1
Garner, RC; Smith, JR; Wood, ML1
Loechler, EL; Teeter, MM; Whitlow, MD1
Autrup, H; Harris, CC; Vahakangas, K; Wakhisi, J; Wasunna, A1
Kuwahara, J; Sugiura, Y; Suzuki, T1
Chetsanga, CJ; Frenette, GP1
Autrup, H; Bradley, KA; Shamsuddin, AK; Wakhisi, J; Wasunna, A1
Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA1
Den Engelse, L; Kriek, E; Scherer, E; Westra, JG1
Bennett, RA; Essigmann, JM; Wogan, GN1
Chu, YH; Craig, AW; O'Connor, PJ1
Croy, RG; Groopman, JD; Wogan, GN1
Chu, FS; Li, YK; Pestka, JJ1
Chu, YH; Margison, GP; Maru, GB; O'Connor, PJ1
Johnston, DS; Stone, MP2
Groopman, JD; Weaver, VM1
Groopman, JD; Hasler, J; Junshi, C; Kensler, TW; Wild, CP; Wogan, GN1
Judah, DJ; Neal, GE; Olubuyide, IO; Riley, J; Seawright, AA; Snowden, RT1
Groopman, JD; Grossman, L; Lim, SE; Mayernik, JA; Oleykowski, CA; Wogan, GN; Yeung, AT1
Bailey, EA; Essigmann, JM; Harris, TM; Iyer, RS; Stone, MP1
Chen, CJ; Liaw, YF; Lien, JP; Yu, MW1
Groopman, JD; Kensler, TW1
Groopman, JD; Kamataki, T; Katsuki, M; Li, Y; Wang, JS; Yokoi, T1
Chen, CJ; Chiang, YC; Lien, JP; Yu, MW1
Sashidhar, RB; Sujatha, N; Vidyasagar, T2
Campbell, TC; Lange, T; Root, M1
Essigmann, JM; Kobertz, WR; Marzilli, LA; Vouros, P; Wang, D1
Mathison, BH; Ross, MK; Said, B; Shank, RC1
Ross, MK; Said, B; Shank, RC1
Bhat, RV; Nayak, S; Sashidhar, RB1
Bailey, GS; Egner, PA; Gange, SJ; Groopman, JD; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Qian, GS; Wang, JB; Wu, Y; Zhang, BC; Zhang, QN; Zhu, YR1
Essigmann, JM; Hamm, ML; Harris, CM; Harris, TM; Henderson, PT; Smela, ME1
Giri, I; Stone, MP1
Egner, PA; Groopman, JD; Johnson, JK; Kensler, TW; Nathasingh, CK; Roebuck, BD; Yu, X1
El-Nezami, H; Juvonen, RO; Kemiläinen, H; Ling, W; Ma, J; Mykkänen, H; Mykkänen, O; Polychronaki, N; Salminen, E; Salminen, S; Zhu, H1
Alessi, M; Bedard, LL; Davey, S; Massey, TE1
El-Nezami, HS; Juvonen, RO; Ling, W; Ma, J; Mykkänen, HM; Polychronaki, NN; Poussa, T; Salminen, EK; Salminen, SJ; Zhu, H1
Egner, PA; Friesen, MD; Groopman, JD; Kensler, TW; Wang, JS1
Bren, U; Guengerich, FP; Mavri, J1
Nayak, S; Sashidhar, RB1
Banitaba, MH; Davarani, SS; Mehdinia, A1
Croy, RG; Egner, PA; Essigmann, JM; Fiala, JL; Groopman, JD; Kensler, KH; Ruchirawat, M; Wiriyachan, N; Wogan, GN1
Belanger, CL; Bouhenguel, JT; Croy, RG; Egner, PA; Essigmann, JM; Groopman, JD; Trudel, LJ; Wattanawaraporn, R; Wogan, GN; Woo, LL1
Asim, M; Kar, P; Sarma, MP; Thayumanavan, L1
Baptista, GZ; Jager, AV; Oliveira, CA; Souto, PC; Tonin, FG1
Chawanthayatham, S; Croy, RG; Egner, PA; Essigmann, JM; Fedeles, BI; Groopman, JD; Satayavivad, J; Slocum, SL; Sriwattanapong, K1
He, L; Li, D; Liu, L; Liu, W; Shu, W; Tan, Y; Wang, J; Wang, L; Zhao, X; Zheng, C1
Kellum, AH; Lloyd, RS; McCullough, AK; Minko, IG; Stone, MP; Tomar, R; Voehler, MW1
Apolinário, LA; Augusto, MJ; Jager, AV; Khaneghah, AM; Moosavi, MH; Oliveira, CAF; Petta, T; Ramalho, FS; Ramalho, LNZ; Trotta, MR1

Reviews

5 review(s) available for aflatoxin b1 and guanine

ArticleYear
The structure of the aflatoxin B1-DNA adduct at N7 of guanine. Theoretical intercalation and covalent adduct models.
    Journal of biomolecular structure & dynamics, 1989, Volume: 7, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; DNA; Guanine; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation

1989
Genotoxicity of mycotoxins.
    Developments in toxicology and environmental science, 1986, Volume: 12

    Topics: Aflatoxin B1; Aflatoxins; Animals; Binding Sites; DNA; Guanine; Mutagenicity Tests; Mycotoxins

1986
Enhanced repair of O6-alkylguanine in mammalian tissues.
    Folia biologica, 1984, Volume: 30 Spec No

    Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity

1984
Formation of DNA modifications by chemical carcinogens. Identification, localization and quantification.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies; Antibodies, Monoclonal; Benzo(a)pyrene; Blood-Brain Barrier; Blood-Testis Barrier; Carcinogens; Cyclophosphamide; DNA; DNA, Single-Stranded; Ethylnitrosourea; Female; Guanine; Histocytochemistry; Humans; Liver; Male; Nucleic Acid Conformation; Respiratory System; Spectrometry, Fluorescence; Tissue Distribution

1984
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 25

    Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes

1996

Trials

2 trial(s) available for aflatoxin b1 and guanine

ArticleYear
Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Animals; Biomarkers; Carcinoma, Hepatocellular; China; Chlorophyllides; DNA Adducts; Female; Food Contamination; Guanine; Humans; Liver Neoplasms; Male; Middle Aged; Risk Factors

2001
Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:5

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; China; DNA Adducts; Double-Blind Method; Guanine; Humans; Lacticaseibacillus rhamnosus; Liver Neoplasms; Placebos; Probiotics; Propionibacterium; Risk Factors

2006

Other Studies

55 other study(ies) available for aflatoxin b1 and guanine

ArticleYear
Aflatoxin B1 and DNA adducts. Proposed model for surface noncovalent and covalent complexes with N(7) of guanine. II.
    Journal of biomolecular structure & dynamics, 1992, Volume: 10, Issue:3

    Topics: Aflatoxin B1; Base Sequence; Binding Sites; DNA; DNA Adducts; Guanine; Molecular Conformation; X-Ray Diffraction

1992
Molecular dosimetry in rat urine of aflatoxin-N7-guanine and other aflatoxin metabolites by multiple monoclonal antibody affinity chromatography and immunoaffinity/high performance liquid chromatography.
    Cancer research, 1992, Jan-15, Volume: 52, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antibody Affinity; Chromatography, Affinity; Chromatography, High Pressure Liquid; Guanine; Rats; Regression Analysis

1992
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
    Carcinogenesis, 1992, Volume: 13, Issue:1

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes

1992
Immunological and HPLC detection of aflatoxin adducts in human tissues after an acute poisoning incident in S.E. Asia.
    Carcinogenesis, 1991, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Asia, Southeastern; Carcinogens; Child; Chromatography, High Pressure Liquid; DNA; Enzyme-Linked Immunosorbent Assay; Female; Guanine; Humans; Kidney; Liver; Lung; Male; Middle Aged; Poisoning

1991
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
    Nucleic acids research, 1991, Mar-25, Volume: 19, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids

1991
Properties of aflatoxin-DNA adducts formed by photoactivation and characterization of the major photoadduct as aflatoxin-N7-guanine.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes; Photochemistry; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Ultraviolet Rays

1990
Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences.
    Biochemistry, 1988, Jan-12, Volume: 27, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Base Sequence; DNA; DNA Restriction Enzymes; Guanine; Polydeoxyribonucleotides; Protein Binding; Structure-Activity Relationship

1988
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Enzyme Induction; Ethoxyquin; gamma-Glutamyltransferase; Glutathione Transferase; Guanine; Liver; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344

1986
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
    Cancer research, 1987, Jul-01, Volume: 47, Issue:13

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; DNA Damage; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Kenya; Liver Neoplasms; Male; Sex Factors

1987
DNA replication-blocking properties of adducts formed by aflatoxin B1-2,3-dichloride and aflatoxin B1-2,3-oxide.
    Mutation research, 1987, Volume: 179, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Base Composition; DNA; DNA Damage; DNA Replication; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Guanine; Magnesium; Manganese; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid

1987
Structural characterization of the major adducts obtained after reaction of an ultimate carcinogen aflatoxin B1-dichloride with calf thymus DNA in vitro.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Thymus Gland

1988
Mapping the binding site of aflatoxin B1 in DNA: molecular modeling of the binding sites for the N(7)-guanine adduct of aflatoxin B1 in different DNA sequences.
    Journal of biomolecular structure & dynamics, 1988, Volume: 5, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Base Sequence; Binding Sites; DNA; Guanine; Intercalating Agents; Models, Molecular

1988
Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Age Factors; Child; Environmental Exposure; Female; Geography; Guanine; Humans; Kenya; Male; Middle Aged; Sex Factors

1985
Nucleotide sequence cleavage of guanine-modified DNA with aflatoxin B1, dimethyl sulfate, and mitomycin C by bleomycin and deoxyribonuclease I.
    Biochemical and biophysical research communications, 1983, Dec-28, Volume: 117, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Base Sequence; Bleomycin; Chemical Phenomena; Chemistry; Deoxyribonuclease I; DNA; Endodeoxyribonucleases; Guanine; Mitomycin; Mitomycins; Sulfuric Acid Esters; Sulfuric Acids

1983
Excision of aflatoxin B1-imidazole ring opened guanine adducts from DNA by formamidopyrimidine-DNA glycosylase.
    Carcinogenesis, 1983, Volume: 4, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; DNA; DNA-Formamidopyrimidine Glycosylase; Escherichia coli Proteins; Guanine; Imidazoles; Kinetics; Liver; N-Glycosyl Hydrolases; Rats; Rats, Inbred F344

1983
Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya.
    Carcinogenesis, 1983, Volume: 4, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Biotransformation; Guanine; Humans; Kenya; Spectrometry, Fluorescence

1983
Excretion of an aflatoxin-guanine adduct in the urine of aflatoxin B1-treated rats.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guanine; Rats

1981
Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.
    British journal of cancer, 1981, Volume: 43, Issue:6

    Topics: Adenine; Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Rats; Stimulation, Chemical

1981
In vitro reactions of aflatoxin B1-adducted DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Apurinic Acid; Chemical Phenomena; Chemistry; DNA; Guanine; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation

1981
Reactivity of aflatoxin B2a antibody with aflatoxin B1-modified DNA and related metabolites.
    Applied and environmental microbiology, 1982, Volume: 44, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Antibodies; Antibody Specificity; Cross Reactions; DNA; Enzyme-Linked Immunosorbent Assay; Guanine

1982
Effects of carcinogens and partial hepatectomy upon the hepatic O6-methylguanine repair system in mice.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell-Free System; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Hepatectomy; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rats; Rats, Inbred Strains

1982
Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR.
    Biochemistry, 1995, Oct-31, Volume: 34, Issue:43

    Topics: Aflatoxin B1; Base Sequence; Dinucleoside Phosphates; DNA; DNA Adducts; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons; Solutions

1995
Fluorescence quantification of aflatoxin N7-guanine adducts.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:8

    Topics: Aflatoxin B1; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Hydrolysis; Male; Rats; Rats, Inbred F344; Spectrometry, X-Ray Emission

1994
Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Animals; Biomarkers; China; DNA; DNA Adducts; DNA Damage; Female; Gambia; Guanine; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Rats, Inbred F344

1993
A comparison of the effects of aflatoxin B1 on the livers of rats and duck hepatitis B virus-infected and noninfected ducks.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Aflatoxin B1; Animals; Blotting, Southern; Chromatography, High Pressure Liquid; DNA; Ducks; Guanine; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Weight Gain

1993
Repair of aflatoxin B1 DNA adducts by the UvrABC endonuclease of Escherichia coli.
    The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

    Topics: Aflatoxin B1; Base Sequence; DNA Damage; DNA Repair; DNA, Superhelical; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Guanine; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Substrate Specificity

1993
Mutational properties of the primary aflatoxin B1-DNA adduct.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-20, Volume: 93, Issue:4

    Topics: Aflatoxin B1; Bacteriophage M13; Base Sequence; Carcinoma, Hepatocellular; DNA Adducts; DNA, Viral; Escherichia coli; Guanine; Humans; Liver Neoplasms; Models, Molecular; Molecular Sequence Data; Mutagenesis; SOS Response, Genetics; Structure-Activity Relationship

1996
Effects of multiple risk factors for hepatocellular carcinoma on formation of aflatoxin B1-DNA adducts.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:8

    Topics: Aflatoxin B1; Age Factors; Alcohol Drinking; Biomarkers; Carcinogens; Carcinoma, Hepatocellular; Carrier State; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Logistic Models; Male; Multivariate Analysis; Prospective Studies; Risk Factors; Smoking; Taiwan

1996
In vivo activation of aflatoxin B1 in C57BL/6N mice carrying a human fetus-specific CYP3A7 gene.
    Cancer research, 1997, Feb-15, Volume: 57, Issue:4

    Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; DNA; DNA Damage; Fetus; Guanine; Humans; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic

1997
Plasma antioxidant vitamins, chronic hepatitis B virus infection and urinary aflatoxin B1-DNA adducts in healthy males.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Adult; Aflatoxin B1; Aged; Antioxidants; beta Carotene; Carotenoids; Chronic Disease; DNA; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Testosterone; Vitamin E; Vitamins

1997
Determination of aflatoxin B1-DNA adduct in rat liver by enzyme immunoassay.
    The Analyst, 1997, Volume: 122, Issue:6

    Topics: Aflatoxin B1; Animals; Antigens; Carcinogens; Cattle; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Guanine; Liver; Male; Rabbits; Rats; Rats, Inbred F344; Serum Albumin, Bovine

1997
Direct synthesis of aflatoxin B1-N7 guanine adduct: a reference standard for biological monitoring of dietary aflatoxin exposure in molecular epidemiological studies.
    Food additives and contaminants, 1997, Volume: 14, Issue:5

    Topics: Aflatoxin B1; Chlorobenzoates; Chromatography, High Pressure Liquid; Food Analysis; Guanine; Reference Standards

1997
Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver.
    Chemico-biological interactions, 1997, Oct-24, Volume: 106, Issue:3

    Topics: Administration, Oral; Aflatoxin B1; Animals; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344

1997
Mass spectral identification and positional mapping of aflatoxin B1-guanine adducts in oligonucleotides.
    Journal of the American Society for Mass Spectrometry, 1998, Volume: 9, Issue:7

    Topics: Aflatoxin B1; Carcinogens; DNA Adducts; Guanine; Indicators and Reagents; Mass Spectrometry; Oligonucleotides

1998
5-Methylcytosine in CpG sites and the reactivity of nearest neighboring guanines toward the carcinogen aflatoxin B1-8,9-epoxide.
    Biochemical and biophysical research communications, 1999, Jan-08, Volume: 254, Issue:1

    Topics: 5-Methylcytosine; Aflatoxin B1; Carcinogens; Cytosine; Gene Expression Regulation, Neoplastic; Genes, p53; Guanine; Humans; Oligonucleotides

1999
DNA-damaging effects of genotoxins in mixture: modulation of covalent binding to DNA.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:2

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Binding, Competitive; Cattle; DNA; DNA Adducts; DNA Damage; Guanine; Mutagens; Sulfuric Acid Esters

2000
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I.
    Chemical research in toxicology, 2000, Volume: 13, Issue:11

    Topics: Aflatoxin B1; DNA; DNA Adducts; DNA Polymerase I; DNA Replication; Exonucleases; Guanine; Oligonucleotides; Templates, Genetic

2000
Quantification and validation of enzyme immunoassay for urinary aflatoxin B1-N7-guanine adduct for biological monitoring of aflatoxins.
    The Analyst, 2001, Volume: 126, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA Adducts; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Female; Food Contamination; Guanine; Humans; Male; Rabbits; Rats; Rats, Inbred F344

2001
The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, May-14, Volume: 99, Issue:10

    Topics: Aflatoxin B1; Bacteriophage M13; Carcinoma, Hepatocellular; DNA Adducts; DNA, Neoplasm; DNA, Viral; Guanine; Humans; Liver Neoplasms; Molecular Structure; Mutagenesis; Mutagens; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Wobble dC.dA pairing 5' to the cationic guanine N7 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 adduct: implications for nontargeted AFB1 mutagenesis.
    Biochemistry, 2003, Jun-17, Volume: 42, Issue:23

    Topics: Aflatoxin B1; Base Composition; Base Pair Mismatch; Base Sequence; Cations; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Protons; Structure-Activity Relationship

2003
Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B1.
    Chemical research in toxicology, 2003, Volume: 16, Issue:9

    Topics: Administration, Oral; Aflatoxin B1; Aflatoxin M1; Animals; Chromatography, Liquid; DNA Adducts; DNA Damage; Guanine; Hydroxylation; Liver; Male; Mass Spectrometry; Microsomes, Liver; Models, Animal; Rats; Rats, Inbred F344; Tupaiidae

2003
Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males.
    International journal of cancer, 2005, Jul-20, Volume: 115, Issue:6

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; China; Feces; Guanine; Hepatitis B; Humans; Male

2005
Susceptibility to aflatoxin B1-induced carcinogenesis correlates with tissue-specific differences in DNA repair activity in mouse and in rat.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; DNA; DNA Repair; Female; Genetic Predisposition to Disease; Guanine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Mice; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity

2005
Quantification of aflatoxin-B1-N7-Guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry.
    Chemical research in toxicology, 2006, Volume: 19, Issue:9

    Topics: Aflatoxin B1; Chromatography, High Pressure Liquid; Guanine; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity

2006
Guanine alkylation by the potent carcinogen aflatoxin B1: quantum chemical calculations.
    Chemical research in toxicology, 2007, Volume: 20, Issue:8

    Topics: Aflatoxin B1; Algorithms; Alkylation; Carcinogens; DNA; Energy Transfer; Epoxy Compounds; Guanine; Kinetics; Models, Molecular; Quantum Theory

2007
Metabolic intervention of aflatoxin B1 toxicity by curcumin.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Aflatoxin B1; Albumins; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcuma; Curcumin; Dietary Supplements; DNA Adducts; Enzymes; Guanine; Inactivation, Metabolic; Liver; Male; Phytotherapy; Plant Extracts; Rats

2010
Study of interactions between DNA and aflatoxin B1 using electrochemical and fluorescence methods.
    Analytical biochemistry, 2011, Apr-15, Volume: 411, Issue:2

    Topics: Aflatoxin B1; Biosensing Techniques; Carbon; DNA; Electrochemical Techniques; Electrodes; Guanine; Ionic Liquids; Pyridinium Compounds; Spectrometry, Fluorescence

2011
Sulforaphane-mediated reduction of aflatoxin B₁-N⁷-guanine in rat liver DNA: impacts of strain and sex.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 121, Issue:1

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; Dose-Response Relationship, Drug; Female; Guanine; Isothiocyanates; Liver; Male; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Sulfoxides; Thiocyanates

2011
Aflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:1

    Topics: Aflatoxin B1; Age Factors; Animals; Animals, Newborn; Base Sequence; Carcinogenicity Tests; Carcinoma, Hepatocellular; DNA Adducts; Female; Guanine; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutagens; Mutation Rate; Sequence Analysis, DNA; Sex Factors

2011
Role of aflatoxin B1 as a risk for primary liver cancer in north Indian population.
    Clinical biochemistry, 2011, Volume: 44, Issue:14-15

    Topics: Adult; Aflatoxin B1; Alcohol Drinking; Carcinoma, Hepatocellular; Case-Control Studies; Chronic Disease; Female; Food Analysis; Food Microbiology; Guanine; Hepatitis B; Hepatitis C; Humans; India; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Risk Factors

2011
Assessment of aflatoxin exposure using serum and urinary biomarkers in São Paulo, Brazil: A pilot study.
    International journal of hygiene and environmental health, 2016, Volume: 219, Issue:3

    Topics: Adult; Aflatoxin B1; Aflatoxin M1; Arachis; Biomarkers; Brazil; Dairy Products; Diet; Environmental Monitoring; Food Contamination; Guanine; Humans; Lysine; Middle Aged; Pilot Projects; Zea mays

2016
Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, Nov-01, Volume: 160, Issue:1

    Topics: Activation, Metabolic; Aflatoxin B1; Animals; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; DNA Adducts; DNA Damage; Female; Gestational Age; Glutathione Transferase; Guanine; Hepatocytes; Isoenzymes; Liver; Maternal Exposure; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy

2017
Microcystin-LR increases genotoxicity induced by aflatoxin B1 through oxidative stress and DNA base excision repair genes in human hepatic cell lines.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 233

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Catalase; Comet Assay; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glutathione; Guanine; Hepatocytes; Humans; Liver Neoplasms; Marine Toxins; Microcystins; Oxidative Stress; Superoxide Dismutase; Toxicity Tests

2018
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B
    Chemical research in toxicology, 2021, 03-15, Volume: 34, Issue:3

    Topics: Aflatoxin B1; Base Sequence; Biocatalysis; DNA; DNA Adducts; DNA Glycosylases; Guanine; Humans; Molecular Structure; Pyrimidines

2021
Oncogenic and tumor suppressor pathways in subchronic aflatoxicosis in rats: Association with serum and urinary aflatoxin exposure biomarkers.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 153

    Topics: Aflatoxin B1; Aflatoxin M1; Alanine Transaminase; Animals; Aspartate Aminotransferases; beta Catenin; Biomarkers; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Gene Expression; Guanine; Hepatocytes; Liver; Lysine; Male; Precancerous Conditions; Rats, Wistar; Retinoblastoma Protein

2021