Page last updated: 2024-08-21

aflatoxin b1 and benzo(a)pyrene

aflatoxin b1 has been researched along with benzo(a)pyrene in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-199039 (33.05)18.7374
1990's48 (40.68)18.2507
2000's12 (10.17)29.6817
2010's16 (13.56)24.3611
2020's3 (2.54)2.80

Authors

AuthorsStudies
Butterworth, BE; Eldridge, SR; Gould, MN1
Linko, P; Liu, YH; Lucier, GW; Taylor, J; Thompson, CL1
Nath, J; Ong, TM; Warner, JR1
Abraham, SK1
Lee, MS; Wang, CY; Zukowski, K1
Said, B; Shank, RC1
Bauchinger, M; Kulka, U; Paul, D; Salassidis, K; Schmid, E1
Paumgartten, FJ; Röscheisen, C; Speit, G; Zamith, H1
Groopman, J; Lim, S; Ozturk, M; Puisieux, A1
Ersing, N; Faletto, MB; Gurtoo, HL; Kouli, F; Maccubbin, AE; Vangalio, JA1
Rubano, DC; Strother, A; Teel, RW1
Friederich, U; Grüter, A; Würgler, FE1
Busbee, DL; Norman, JO; Ziprin, RL1
Arlotto, MP; Crespi, CL; Davies, RL; Leakey, JA; Parkinson, A; Penman, BW; Rudo, K; Stark, A; Steimel, DT; Turner, T1
Cassand, P; Colin, C; Daubeze, M; Leveque, F; Narbonne, JF1
Cassand, P; Decoudu, S; Leveque, F; Narbonne, JF1
Dutcher, JS; Henderson, TR; Howard, AJ; McClellan, RO; Mitchell, CE1
Athar, M; Bickers, DR; Cheng, SJ; Khan, WA; Mukhtar, H; Wang, ZY; Zhou, ZC1
Faletto, MB; Gurtoo, HL; Koser, PL; Maccubbin, AE; Vangalio, JA1
Dvorackova, I; Garner, RC; Tursi, F1
Gurtoo, HL; Raina, V1
Al-Sabti, K1
Carluccio, MA; Gemperlein, I; Glatt, HR; Oesch, F; Turchi, G1
Armel, P; Williams, GM1
Würgler, FE1
Huang, CC; Qin, S1
Bjeldanes, LF; Hendrich, S1
Harris, CC; Hsu, IC; Lipsky, MM; Snyder, S; Trump, BF1
Chen, XR; Sun, L; Yu, YN1
Combes, RD; Walters, JM1
Bakke, JP; Green, CE; Mirsalis, JC; Spak, DK; Steinmetz, KL1
Felton, JS; Fuscoe, JC; Healy, SK; Shen, NH; Wu, R1
Fukuhara, M; Ohno, Y; Sunouchi, M; Takanaka, A1
Black, JJ; Maccubbin, AE; Schiffert, M1
Gurtoo, HL; Koser, P; Raina, V1
Jones, PA; Wilson, VL1
Autrup, H; Essigmann, JM; Harris, CC; Schwartz, RD; Smith, L; Trump, BF1
Cortesi, E; Donovan, PJ; Kakunaga, T; Rice, JM; Saffiotti, U1
Collins, MA; Cottrell, RC; Gangolli, SD; Harris, RA; Lake, BG; Phillips, JC; Rowland, IR1
Curtis, G; Garland, H; Nesnow, S1
Huh, N; Nemoto, N; Utakoji, T1
Gould, MN1
Akintonwa, DA1
Loquet, C; Wiebel, FJ1
Goldstein, JA; Robertson, IG; Zeiger, E1
Hsia, MT1
Heidelberger, C; Landolph, JR; Link, KH1
Friesen, E; Israels, ED; Israels, LG; Ollmann, DJ; Walls, GA1
Baker, RS; Meher-Homji, KM; Mitchell, GA; Podobna, E1
Choe, SY; Kim, DH; Shin, CG; Yang, KH1
Autrup, H; Bao, LY; Harris, CC; Hsia, CC; Lu, S; Pei, XF; Sun, TT; Wu, SM1
Avadhani, NG; Jefcoate, CR; Niranjan, BG; Wilson, NM1
Hall, SD; Lee, AM; Murison, GL1
Den Engelse, L; Kriek, E; Scherer, E; Westra, JG1
Hopkin, JM1
Bagnasco, M; Bennicelli, C; Bojnemirski, A; Camoirano, A; De Flora, S; Kurelec, B1
Chou, MW; Chung, KT; Hart, RW; Kong, J1
Borgerding, MF; Chang, KM; Doolittle, DJ; Fulp, C; Lee, CK; Munoz, JA; Rogers, JC1
Itahashi, K; Kamataki, T; Kato, T; Kitada, M; Nakasa, H; Ohmori, S; Rikihisa, T; Shimada, T1
al-Maskati, HA; Dairi, MG; el-Din, AY; Mohamed, AY1
Casciano, DA; Chou, MW; Hart, RW; Kong, J; Shaddock, JG1
Abdelali, H; Bouley, C; Cassand, P; Denariaz, G; Narbonne, JF1
Ball, RW; Coulombe, RA; Huie, JM1
Aleixandre, V; Blanco, M; Herrera, G; Sommer, S; Urios, A1
Montague, W; Raza, H1
Itoh, S; Kamataki, T; Sawada, M; Tagawa, S1
Crutzen-Fayt, MC; Gerber, GB; Hilali, A; Léonard, A1
Bauchinger, M; Doehmer, J; Glatt, HR; Kulka, U1
Kelly, MD; Park, BK; Tingle, MD; Wilson, AS1
al-Dakan, AA; al-Tuffail, M; Hannan, MA1
Bruijntjes-Rozier, GC; Evertz, SJ; Rompelberg, CJ; van den Heuvel, PD; Verhagen, H1
Dauterman, WC; DeMarini, DM; Woodall, GM2
Galloway, SM; Johnson, TE; Umbenhauer, DR1
Nash, RA1
Choi, MJ; Lee, BM; Lee, JW1
Horský, J; Pitha, J1
Duh, PD; Yen, GC1
Crespi, CL; Penman, BW; Smith, T; Steimel, DT; Sutter, TR; Yang, CS1
Chen, W; Chou, MW; Chung, KT; Hart, RW; Jackson, CD; Mikhailova, MV; Nichols, J; Weis, C1
Kranendonk, M; Laires, A; Mesquita, P; Rueff, J; Vermeulen, NP1
Kusamran, WR; Ratanavila, A; Tepsuwan, A1
Adav, SS; Govindwar, SP1
Harris, CC; Hussain, SP1
Hengstler, JG; Oesch, F; Steinberg, P; Van der Burg, B1
Monti, R; Tavares, DC; Varanda, EA1
Athar, M; Raisuddin, S; Sharma, N; Trikha, P1
Fujita, K; Kamataki, T; Muto, S; Yamazaki, Y1
de Boer, JG1
Chen, CF; Liao, JF; Lin, YL; Liu, TY; Oda, Y; Shyu, CC; Ueng, YF1
Cavin, C; Constable, A; Holzhaeuser, D; Huber, WW; Scharf, G; Schilter, B1
Ajith, TA; Joseph, S; Kuttan, R; Raphael, KR1
Fu, J; Jiang, X; Li, H; Qi, J1
Arimoto-Kobayashi, S; Fujita, K; Kamataki, T; Negishi, T; Okamoto, K; Takahashi, E1
Dávila, VM; Ito, A; Montero, R; Plancarte, A; Serrano, L1
Jin, Y; Xu, Z1
Biso, FI; Cardoso, CR; Longo, Mdo C; Nogueira, ME; Passoni, MH; Santos, LC; Varanda, EA1
Byun, SH; Kim, HS; Lee, BM1
Chen, L; Chen, W; Ji, W; Lai, Y; Li, D; Li, W; Lin, Y; Ma, R; Pang, Y; Tang, S; Wang, Q; Wei, Q; Xiao, Y; Yang, P; Zheng, Y; Zhuang, Z1
Angeli, JP; Barbosa, F; Barcelos, GR; Mantovani, MS; Nersesyan, A; Serpeloni, JM1
Boyd, WA; Freedman, JH; Goldstone, JV; Leung, MC; Meyer, JN1
Callegari, E; Elamin, BK; Gramantieri, L; Negrini, M; Sabbioni, S1
André, V; Billet, S; Garçon, G; Goff, JL; Lechevrel, M; Paget, V; Pottier, D; Shirali, P; Sichel, F1
Fessard, V; Huet, S; Le Hégarat, L1
Chesné, C; Claessen, SM; Jetten, MJ; Kleinjans, JC; van Delft, JH1
Castell, JV; Claessen, SM; Dejong, CH; Jetten, MJ; Kleinjans, JC; Lahoz, A; van Delft, JH1
Aubrecht, J; Buick, JK; Fornace, AJ; Hyduke, DR; Li, HH; Moffat, I; Recio, L; Swartz, CD; Williams, A; Yauk, CL1
Audebert, M; Glaise, D; Loyer, P; Martinais, S; Morel, F; Quesnot, N; Robin, MA; Rondel, K1
Beland, FA; Marrone, AK; Pogribny, IP; Tryndyak, V1
Jennen, DGJ; Kleinjans, JCS; Smit, E; Souza, T; van den Beucken, T1
Ferk, F; Filipič, M; Haas, O; Haslinger, E; Huber, WW; Knasmüller, S; Mai, S; Mikulits, W; Mišík, M; Tomc, J; Waldherr, M; Žegura, B1
Breznik, B; Filipič, M; Kamenšek, U; Kološa, K; Tomc, J; Turnšek, TL; Žegura, B1
Beland, FA; Churchwell, MI; Dreval, K; Kindrat, I; Pogribny, IP; Tryndyak, V1
Cao, Y; Chen, R; Han, L; Liu, W; Luan, Y; Pan, G; Xi, J; You, X; Zhang, X1
Auerbach, SS; Bushel, PR; DeVito, MJ; Dunlap, PE; Ferguson, SS; Merrick, BA; Paules, RS; Ramaiahgari, SC; Rice, JR; Saddler, TO; Shah, RR; Sipes, NS1
Chen, Y; Hu, K; Li, Z; Liu, Y; Zhu, N1
Carpi, D; Lloyd, GR; Malinowska, JM; Palosaari, T; Sund, J; Viant, MR; Weber, RJM; Whelan, M1
Guan, X; Li, W; Lv, Y; Sun, Y; Wang, Y; Wu, Y; Yu, M1

Reviews

8 review(s) available for aflatoxin b1 and benzo(a)pyrene

ArticleYear
Toxicological significance of dihydrodiol metabolites.
    Journal of toxicology. Clinical toxicology, 1982, Volume: 19, Issue:6-7

    Topics: Aflatoxin B1; Aflatoxins; Alcohols; Aldrin; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Chemical Phenomena; Chemistry; Cricetinae; Environmental Pollutants; Insecticides; Mutagenicity Tests; Pesticide Residues; Rats; Structure-Activity Relationship

1982
Formation of DNA modifications by chemical carcinogens. Identification, localization and quantification.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies; Antibodies, Monoclonal; Benzo(a)pyrene; Blood-Brain Barrier; Blood-Testis Barrier; Carcinogens; Cyclophosphamide; DNA; DNA, Single-Stranded; Ethylnitrosourea; Female; Guanine; Histocytochemistry; Humans; Liver; Male; Nucleic Acid Conformation; Respiratory System; Spectrometry, Fluorescence; Tissue Distribution

1984
p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer.
    Mutation research, 1999, Jul-16, Volume: 428, Issue:1-2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Carcinogens, Environmental; Codon; Genes, p53; Humans; Models, Biological; Mutation; Neoplasms; Nitric Oxide; Sunlight

1999
Interspecies differences in cancer susceptibility and toxicity.
    Drug metabolism reviews, 1999, Volume: 31, Issue:4

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents, Hormonal; Benzo(a)pyrene; Cardiotonic Agents; Cricetinae; Digitoxin; Disease Susceptibility; Endocrine System; Estrogens; Female; Heterocyclic Compounds; Humans; Male; Mice; Microsomes, Liver; Neoplasms; Polychlorinated Dibenzodioxins; Rabbits; Rats; Species Specificity; Tamoxifen

1999
Protection by dietary compounds against mutation in a transgenic rodent.
    The Journal of nutrition, 2001, Volume: 131, Issue:11 Suppl

    Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Bacterial Proteins; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Escherichia coli Proteins; Humans; Imidazoles; Lac Repressors; Mice; Mutagenesis; Mutagens; Mutation; Neoplasms; Rats; Repressor Proteins; Sex Characteristics; Species Specificity

2001
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Cells, Cultured; Coffee; Colorectal Neoplasms; Disease Models, Animal; Diterpenes; Enzyme Induction; Humans; Imidazoles

2002
[Environmental carcinogens and p53 gene mutation].
    Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:2

    Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Carcinogens, Environmental; Genes, p53; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53

2004
MicroRNA response to environmental mutagens in liver.
    Mutation research, 2011, Dec-01, Volume: 717, Issue:1-2

    Topics: Aflatoxin B1; Animals; Arsenic; Benzo(a)pyrene; Carcinoma, Hepatocellular; Environmental Pollutants; Ethanol; Gene Expression Regulation; Hepacivirus; Hepatitis B virus; Humans; Liver; Liver Neoplasms; MicroRNAs; Mutagens; Nicotiana; Poisons; Risk Factors; Rodenticides; Triazines

2011

Other Studies

110 other study(ies) available for aflatoxin b1 and benzo(a)pyrene

ArticleYear
Genotoxicity of environmental agents in human mammary epithelial cells.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Benzo(a)pyrene; Breast; DNA Repair; DNA, Neoplasm; Environmental Pollutants; Epithelial Cells; Epithelium; Female; Humans; Mutagenicity Tests; Pyrenes

1992
Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts.
    Carcinogenesis, 1991, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Aged, 80 and over; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, High Pressure Liquid; Cytosol; Dinitrochlorobenzene; DNA; Female; Glutathione Transferase; Humans; Liver; Liver Neoplasms; Lymphocytes; Male; Middle Aged; Polymorphism, Genetic; Pyrimidines; Stilbenes

1991
Antimutagenicity studies of chlorophyllin using the Salmonella arabinose-resistant assay system.
    Mutation research, 1991, Volume: 262, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Air Pollutants; Anthracenes; Benzo(a)pyrene; Carcinogens; Chlorophyllides; Coal; DNA; Dose-Response Relationship, Drug; Fossil Fuels; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutation; Plants, Toxic; Salmonella typhimurium; Tobacco, Smokeless; Wine

1991
Inhibitory effects of coffee on the genotoxicity of carcinogens in mice.
    Mutation research, 1991, Volume: 262, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Bone Marrow; Carcinogens; Coffee; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Mutation; Urethane

1991
Inhibition by diacylmethane derivatives of mutagenicity in Salmonella typhimurium and tRNA-binding of chemical carcinogens.
    Mutation research, 1991, Volume: 262, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Benzo(a)pyrene; Benzoates; Butanones; Carcinogens; Chalcones; Dose-Response Relationship, Drug; Hydroxylamines; Indans; Methane; Methylnitrosourea; Mutagens; Pentanones

1991
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
    Nucleic acids research, 1991, Mar-25, Volume: 19, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids

1991
Induction of chromosome aberrations and sister chromatid exchange by indirectly acting mutagens in immortal mouse and rat hepatocyte lines.
    Mutagenesis, 1991, Volume: 6, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromosome Aberrations; Cyclophosphamide; Liver; Mice; Mutagenicity Tests; Mutagens; Rats; Sister Chromatid Exchange

1991
Influence of beta-myrcene on sister-chromatid exchanges induced by mutagens in V79 and HTC cells.
    Mutation research, 1991, Volume: 264, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyclic Monoterpenes; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Monoterpenes; Mutagens; Sister Chromatid Exchange; Terpenes

1991
Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens.
    Cancer research, 1991, Nov-15, Volume: 51, Issue:22

    Topics: Aflatoxin B1; Base Sequence; Benzo(a)pyrene; DNA; DNA Fingerprinting; Genes, p53; Humans; Molecular Sequence Data; Mutation; Neoplasms

1991
Altered benzo[a]pyrene metabolism in C3H/10T1/2 cells transformed by aflatoxin B1 or 3-methylcholanthrene.
    Toxicology and applied pharmacology, 1990, Jun-15, Volume: 104, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Adducts; gamma-Glutamyltransferase; Glucuronosyltransferase; Glutathione Transferase; Inactivation, Metabolic; Methylcholanthrene

1990
Effect of glucose administration on hamster liver S9-mediated mutagenesis, metabolism and DNA-binding of benzo[a]pyrene and aflatoxin B1.
    Cancer letters, 1990, Jul-16, Volume: 52, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Cricetinae; DNA; DNA Damage; Glucose; Glucuronates; Glutathione; Liver; Male; Microsomes, Liver; Mutagenicity Tests; Mutation; Sulfates

1990
Antimutagenic effects of mushrooms.
    Mutation research, 1990, Volume: 231, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxin B1; Aflatoxins; Aminacrine; Basidiomycota; Benzo(a)pyrene; DNA Repair; Ethanol; Fluorenes; Hot Temperature; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutation; Nitrogen Mustard Compounds

1990
Comparative uptake, vascular transport, and cellular internalization of aflatoxin-B1 and benzo(a)pyrene.
    Archives of toxicology, 1990, Volume: 64, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biological Transport; Body Fluids; Carcinogens; Digestive System; Fibroblasts; Intracellular Fluid; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Lymph; Molecular Weight; Palmitates; Sheep; Thoracic Duct

1990
Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Base Sequence; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; DNA; Humans; Molecular Sequence Data; Mutagens

1990
Chemical mutagenicity and cellular status in vitamins A, E and C.
    Food additives and contaminants, 1990, Volume: 7 Suppl 1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Ascorbic Acid; Benzo(a)pyrene; Injections, Intraperitoneal; Male; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Vitamin A; Vitamin E

1990
Relationship between vitamin A dietary intake and mutagenic activity of some chemical carcinogens.
    Food additives and contaminants, 1990, Volume: 7 Suppl 1

    Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Vitamin A

1990
Binding of nitropyrenes and benzo[a]pyrene to mouse lung deoxyribonucleic acid after pretreatment with inducing agents.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Chromatography, High Pressure Liquid; DNA; Lung; Male; Methylene Chloride; Mice; Pyrenes; Vehicle Emissions

1986
Antimutagenic activity of green tea polyphenols.
    Mutation research, 1989, Volume: 223, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Chromosome Aberrations; Cricetinae; DNA Damage; Flavonoids; Free Radicals; Microsomes; Mutagenicity Tests; Mutagens; Nitroso Compounds; Phenols; Polymers; Polyphenols; Sister Chromatid Exchange; Tea

1989
Induction of aryl hydrocarbon hydroxylase and DNA adduct formation in parental and carcinogen transformed C3H/10T1/2 clone 8 cells by benzo[a]pyrene.
    Cancer biochemistry biophysics, 1989, Volume: 10, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; Enzyme Induction; Fibroblasts; Male; Mice; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains

1989
Immunoassay procedures to detect exposure to aflatoxin B1 and benzo(a)pyrene in animals and man at the DNA level.
    International archives of occupational and environmental health, 1988, Volume: 60, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellular; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Liver; Liver Neoplasms; Lung; Male; Rats; Rats, Inbred Strains

1988
Effects of vitamins A, C, and E on aflatoxin B1-induced mutagenesis in Salmonella typhimurium TA-98 and TA-100.
    Teratogenesis, carcinogenesis, and mutagenesis, 1985, Volume: 5, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Ascorbic Acid; Benzo(a)pyrene; Biotransformation; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Tretinoin; Vitamin A; Vitamin E; Vitamin K

1985
Carcinogenic-mutagenic chemicals induced chromosomal aberrations in the kidney cells of three cyprinids.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 82, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aroclors; Benzidines; Benzo(a)pyrene; Carcinogens; Chlorodiphenyl (54% Chlorine); Chromosome Aberrations; Cyprinidae; Kidney; Methylcholanthrene; Mutagens; Species Specificity

1985
Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens.
    Mutagenesis, 1987, Volume: 2, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Division; Cells, Cultured; Clone Cells; Cricetinae; Cricetulus; Epithelial Cells; Epithelium; Karyotyping; Liver; Mutagens; Pyruvate Kinase; Tyrosine Transaminase

1987
The molecular nature of spontaneous and chemically induced mutations in the hypoxanthine-guanine phosphoribosyl transferase gene in rat liver epithelial cells.
    Mutation research, 1988, Volume: 202, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Blotting, Southern; Cell Line; DNA Probes; Epithelium; Hypoxanthine Phosphoribosyltransferase; Liver; Mutation; Polymorphism, Restriction Fragment Length; Rats

1988
Polysubstrate monooxygenases in Drosophila, mammals and man.
    Basic life sciences, 1985, Volume: 34

    Topics: Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Drosophila; Drug Resistance; Enzyme Induction; Humans; Insecticides; Mice; Mutagens; Nitrosamines; Oxygenases; Receptors, Aryl Hydrocarbon; Receptors, Drug; Species Specificity

1985
Influence of mouse liver stored vitamin A on the induction of mutations (Ames tests) and SCE of bone marrow cells by aflatoxin B1, benzo(a)pyrene, or cyclophosphamide.
    Environmental mutagenesis, 1986, Volume: 8, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cyclophosphamide; Liver; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutation; Sister Chromatid Exchange; Vitamin A; Vitamin A Deficiency

1986
Effects of dietary Schizandra chinensis, brussels sprouts and Illicium verum extracts on carcinogen metabolism systems in mouse liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:9

    Topics: 7-Alkoxycoumarin O-Dealkylase; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Cytosol; Drug Interactions; Epoxide Hydrolases; Female; Glutathione; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mutagens; Oxygenases; Plant Extracts; Salmonella typhimurium; Sex Factors; Vegetables

1986
Cell and species differences in metabolic activation of chemical carcinogens.
    Mutation research, 1987, Volume: 177, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cells, Cultured; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA Damage; Fibroblasts; Humans; Liver; Lung; Macrophages; Male; Mice; Mutation; Rats; Species Specificity

1987
A test using cultured cells with induced mixed-function oxygenase in the unscheduled DNA synthesis assay for detecting promutagens/procarcinogens.
    Mutation research, 1987, Volume: 191, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Cells, Cultured; DNA Damage; DNA Repair; Enzyme Induction; Humans; Methylcholanthrene; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens

1987
Activation of benzo[a]pyrene and aflatoxin B1 to mutagenic chemical species by microsomal preparations from rat liver and small intestine in relation to microsomal epoxide hydrolase.
    Mutagenesis, 1986, Volume: 1, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Epoxide Hydrolases; Hydrocarbons, Chlorinated; Intestine, Small; Microsomes; Microsomes, Liver; Mutagens; Rats; Trichloroepoxypropane

1986
Induction of unscheduled DNA synthesis in primary cultures of rat, mouse, hamster, monkey, and human hepatocytes.
    Mutation research, 1988, Volume: 206, Issue:1

    Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Aflatoxins; Aminobiphenyl Compounds; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cricetinae; Dimethyl Sulfoxide; DNA; DNA Repair; Female; Haplorhini; Humans; Liver; Male; Mice; Rats; Species Specificity

1988
Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Base Composition; Base Sequence; Benzo(a)pyrene; Carcinogens; Cloning, Molecular; DNA, Bacterial; Food; Histidine; Imidazoles; Molecular Sequence Data; Mutagens; Operon; Quinolines; Salmonella typhimurium

1988
Effects of various inducers on the activities of cytochrome P-450-mixed function oxidases and aflatoxin B1 activation in microsomes of hamster livers.
    The Journal of toxicological sciences, 1988, Volume: 13, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cricetinae; DNA; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases

1988
A reliable, efficient, microinjection apparatus and methodology for the in vivo exposure of rainbow trout and salmon embryos to chemical carcinogens.
    Journal of the National Cancer Institute, 1985, Volume: 75, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Dimethyl Sulfoxide; Dimethylnitrosamine; Methylnitronitrosoguanidine; Microinjections; Mutagenicity Tests; Salmon; Trout

1985
Differential sensitivity of Ah-responsive mice to beta-naphthoflavone-induced metabolism and mutagenesis of benzo[a]pyrene and aflatoxin B1.
    Journal of toxicology and environmental health, 1985, Volume: 16, Issue:2

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Drug Interactions; Female; Flavonoids; Mice; Mice, Inbred C57BL; Microsomes, Liver

1985
Chemical carcinogen-mediated decreases in DNA 5-methylcytosine content of BALB/3T3 cells.
    Carcinogenesis, 1984, Volume: 5, Issue:8

    Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Fibroblasts; In Vitro Techniques; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenanthrenes

1984
Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon.
    Teratogenesis, carcinogenesis, and mutagenesis, 1980, Volume: 1, Issue:1

    Topics: 1,2-Dimethylhydrazine; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Colon; Dimethylhydrazines; DNA; Humans; Male; Methylhydrazines; Organ Culture Techniques; Rats

1980
Dose-response studies on neoplastic transformation of BALB/3T3 clone A31-1-1 cells by aflatoxin B1, benzidine, benzo[a]pyrene, 3-methylcholanthrene, and N-methyl-N'-nitro-N-nitrosoguanidine.
    Teratogenesis, carcinogenesis, and mutagenesis, 1983, Volume: 3, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzidines; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C

1983
The effect of substrates and inhibitors of monoamine oxidase on hepatic dimethylnitrosamine metabolism and mutagenicity.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt B

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Dimethylnitrosamine; Microsomes, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mutagenicity Tests; Mutation; Rats; Salmonella typhimurium

1981
Improved transformation of C3H10T1/2CL8 cells by direct- and indirect-acting carcinogens.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Methylnitronitrosoguanidine; Mice; Probability

1982
Metabolic activation of benzo[a]pyrene, aflatoxin B1, and dimethylnitrosamine by a human hepatoma cell line.
    Mutation research, 1982, Volume: 94, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Dimethylnitrosamine; Humans; Liver Neoplasms; Middle Aged; Sister Chromatid Exchange

1982
Chemical carcinogen activation in the rat mammary gland: intra-organ cell specificity.
    Carcinogenesis, 1982, Volume: 3, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Specificity; Rats; Rats, Inbred Strains

1982
Some aspects of the human carcinogenicity of aflatoxin B1 and 3, 4 benz [a] pyrene.
    International journal of epidemiology, 1982, Volume: 11, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Humans; Liver Neoplasms; Mice; Rats

1982
Geno- and cytotoxicity of nitrosamines, aflatoxin B1, and benzo[a]-pyrene in continuous cultures of rat hepatoma cells.
    Carcinogenesis, 1982, Volume: 3, Issue:10

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Survival; Clone Cells; Dexamethasone; Diethylnitrosamine; Dimethylnitrosamine; Ethylnitrosourea; Kinetics; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Mutation; Nitrosamines; Rats

1982
Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1.
    Carcinogenesis, 1983, Volume: 4, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Amines; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoenzymes; Mixed Function Oxygenases; Mutagens; NADP; Rats; Salmonella typhimurium

1983
Induction of ouabain-resistant mutants by chemical carcinogens in rat prostate epithelial cells.
    Environmental mutagenesis, 1983, Volume: 5, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cells, Cultured; Drug Resistance; Epithelium; Male; Methylazoxymethanol Acetate; Methylnitronitrosoguanidine; Mutation; Ouabain; Prostate; Rats; Rats, Inbred F344

1983
Vitamin K as a regulator of benzo(a)pyrene metabolism, mutagenesis, and carcinogenesis. Studies with rat microsomes and tumorigenesis in mice.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Female; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Mutagenicity Tests; Mutation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vitamin K; Vitamin K 1; Vitamin K 3; Vitamin K Deficiency

1983
Sensitivity of two Chinese hamster cell lines to SCE induction by a variety of chemical mutagens.
    Mutation research, 1983, Volume: 118, Issue:1-2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Female; Lung; Microsomes, Liver; Mutagenicity Tests; Mutagens; Ovary; Sister Chromatid Exchange; Time Factors

1983
Detection of DNA single-strand breaks induced by procarcinogens in Chinese hamster ovary cells cocultured with rat hepatocytes.
    Journal of toxicology and environmental health, 1984, Volume: 13, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; DNA, Single-Stranded; Female; Liver; Male; Ovary; Rats; Rats, Inbred Strains; Tritium

1984
Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach.
    Chemico-biological interactions, 1984, Volume: 50, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Culture Techniques; DNA; Esophagus; Female; Gestational Age; Humans; Liver; Male; Nitrosamines; Pregnancy; Stomach

1984
Hepatic mitochondrial cytochrome P-450 system. Distinctive features of cytochrome P-450 involved in the activation of aflatoxin B1 and benzo(a)pyrene.
    The Journal of biological chemistry, 1984, Oct-25, Volume: 259, Issue:20

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains; Tritium

1984
Metabolic activation of procarcinogens to genotoxic products in cultured rat liver cells.
    Experimental cell biology, 1984, Volume: 52, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Survival; Cyclophosphamide; Liver; Liver Neoplasms, Experimental; Rats; Sister Chromatid Exchange

1984
Sister chromatid exchange induction by cigarette smoke.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: Adult; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Cells, Cultured; Cricetinae; Female; Humans; Lung Neoplasms; Lymphocytes; Male; Mutagenicity Tests; Nicotiana; Plants, Toxic; Sister Chromatid Exchange; Smoke; Smoking

1984
Biotransformation of genotoxic agents in marine sponges. Mechanisms and modulation.
    Mutagenesis, 1995, Volume: 10, Issue:4

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Carbolines; Glutathione; Glutathione Disulfide; Glutathione Transferase; Inactivation, Metabolic; Microsomes, Liver; Mutagens; Porifera; Quinolines; Rats; Salmonella typhimurium; Species Specificity; Vincristine

1995
Effect of caloric restriction on the metabolic activation of xenobiotics.
    Mutation research, 1993, Volume: 295, Issue:4-6

    Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cells, Cultured; DNA Damage; Energy Intake; Liver; Male; Rats; Rats, Inbred F344; Xenobiotics

1993
Inhibitory activity of cigarette-smoke condensate on the mutagenicity of heterocyclic amines.
    Mutation research, 1994, Volume: 322, Issue:1

    Topics: Aflatoxin B1; Amines; Antimutagenic Agents; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Heterocyclic Compounds; Mutagenicity Tests; Nicotiana; Plants, Toxic; Smoke

1994
Possible occurrence of P450 related to P450 HFLb in extrahepatic tissues of human fetuses and its contribution to metabolic activation of promutagens.
    Mutation research, 1994, Oct-01, Volume: 310, Issue:1

    Topics: Adrenal Glands; Aflatoxin B1; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 Enzyme System; Fetus; Humans; Kidney; Liver; Lung; Mutagens; Quinolines

1994
Acrylamide as an inducer of metabolic activation system (S9) in rats.
    Mutation research, 1993, Volume: 300, Issue:2

    Topics: 2-Acetylaminofluorene; Acrylamide; Acrylamides; Aflatoxin B1; Animals; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide

1993
Effect of dietary restriction on partial hepatectomy-induced liver regeneration of aged F344 rats.
    Cancer letters, 1995, May-08, Volume: 91, Issue:2

    Topics: Aflatoxin B1; Aging; Animals; Benzo(a)pyrene; Biotransformation; Body Weight; Cell Division; DNA; DNA Damage; Energy Intake; Hepatectomy; Liver; Liver Regeneration; Male; Organ Size; Rats; Rats, Inbred F344

1995
Inhibitory effect of dairy products on the mutagenicities of chemicals and dietary mutagens.
    The Journal of dairy research, 1994, Volume: 61, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Bifidobacterium; Cattle; Female; Fluorenes; In Vitro Techniques; Lactobacillus; Male; Milk; Mutagenicity Tests; Quercetin; Rats; Rats, Sprague-Dawley; Salmonella typhimurium

1994
Comparative activation of aflatoxin B1 by mammalian pulmonary tissues.
    Toxicology letters, 1995, Volume: 75, Issue:1-3

    Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Cricetinae; Cytochrome P-450 Enzyme System; In Vitro Techniques; Liver; Lung; Mesocricetus; Organ Specificity; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Subcellular Fractions; Trachea

1995
Mutability of Salmonella tester strains TA1538 (hisD3052) and TA1535 (hisG46) containing the UmuD' and UmuC proteins of Escherichia coli.
    Environmental and molecular mutagenesis, 1994, Volume: 23, Issue:4

    Topics: Aflatoxin B1; Bacterial Proteins; Benzo(a)pyrene; Biotransformation; DNA-Directed DNA Polymerase; Escherichia coli; Escherichia coli Proteins; Frameshift Mutation; Genes, Bacterial; Microsomes, Liver; Mutagenesis, Insertional; Mutagenicity Tests; Mutagens; Operon; Plasmids; Pyrenes; Salmonella typhimurium; SOS Response, Genetics; Species Specificity; Suppression, Genetic

1994
Metabolism of benzo(a)pyrene, dimethylbenzanthracene and aflatoxin B1 by camel liver microsomes.
    Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology, 1994, Volume: 107, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Benzo(a)pyrene; Camelus; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Male; Microsomes, Liver; Rats

1994
High susceptibility to aflatoxin B1 and benzo[a]pyrene of BALB3T3 A31-1-1 cells expressing monkey CYP1A1.
    The Journal of toxicological sciences, 1993, Volume: 18, Issue:3

    Topics: 3T3 Cells; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 Enzyme System; Macaca fascicularis; Mice; Transfection

1993
Effect of age on the ability of rat liver tissues to transform chemical promutagens to mutagens.
    Gerontology, 1993, Volume: 39, Issue:3

    Topics: Aflatoxin B1; Aging; Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; In Vitro Techniques; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats

1993
Cytogenetic effects of promutagens in genetically engineered V79 Chinese hamster cells expressing cytochromes P450.
    European journal of pharmacology, 1993, Apr-01, Volume: 228, Issue:5-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Genetic Engineering; Mutagens; Rats; Sister Chromatid Exchange

1993
Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes.
    Human & experimental toxicology, 1995, Volume: 14, Issue:6

    Topics: 1-Propanol; Adult; Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Cell Division; Environmental Pollutants; Epoxy Compounds; Estrogen Antagonists; Humans; Male; Microsomes, Liver; Mutagens; NADP; Naphthalenes; Propanols; Sister Chromatid Exchange; Spermatogenesis; Stilbenes; T-Lymphocytes; Tamoxifen; Trichloroepoxypropane

1995
Cassia senna inhibits mutagenic activities of benzo[a]-pyrene, aflatoxin B1, shamma and methyl methanesulfonate.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:4

    Topics: Aflatoxin B1; Benzo(a)pyrene; Biotransformation; Cathartics; Dose-Response Relationship, Drug; Histidine; Methyl Methanesulfonate; Mutagenicity Tests; Mutation; Salmonella typhimurium; Senna Extract

1995
Effect of eugenol on the genotoxicity of established mutagens in the liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; DNA; Electrophoresis, Agar Gel; Eugenol; Glutathione Transferase; Humans; Liver; Liver Neoplasms; Male; Micronucleus Tests; Mutagenicity Tests; Mutagens; Rats; Rats, Wistar; Salmonella typhimurium; Tumor Cells, Cultured

1996
Effect of dietary casein levels on activation of promutagens in the spiral Salmonella mutagenicity assay. I. Studies with noninduced rat liver S9.
    Mutation research, 1996, Jun-10, Volume: 360, Issue:2

    Topics: Aflatoxin B1; Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; Body Weight; Caseins; Dietary Proteins; Enzymes; Liver; Male; Mutagenicity Tests; Mutagens; Organ Size; Rats; Rats, Inbred F344; Salmonella

1996
Effect of dietary casein levels on activation of promutagens in the spiral Salmonella mutagenicity assay. II. Studies with induced rat liver S9.
    Mutation research, 1996, Jun-10, Volume: 360, Issue:2

    Topics: Aflatoxin B1; Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; Body Weight; Caseins; Dietary Proteins; Enzymes; Liver; Male; Mutagenicity Tests; Mutagens; Organ Size; Rats; Rats, Inbred F344; Salmonella

1996
Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
    Environmental and molecular mutagenesis, 1996, Volume: 28, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Humans; Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Rats

1996
Commentary on "hydroxypropyl cyclodextrins: potential synergism with carcinogens".
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:7

    Topics: Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Cyclodextrins; Drug Carriers; Drug Synergism; Naphthalenes

1996
Comparative assessment of DNA adduct formation, Salmonella mutagenicity, and chromosome aberration assays as short-term tests for DNA damage.
    Journal of toxicology and environmental health, 1996, Oct-25, Volume: 49, Issue:3

    Topics: Aflatoxin B1; Analysis of Variance; Animals; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Chromosome Aberrations; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Male; Mice; Mutagenesis; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Spleen

1996
Hydroxypropyl cyclodextrins: potential synergism with carcinogens.
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aflatoxin B1; Benzo(a)pyrene; beta-Cyclodextrins; Bile; Carcinogens; Chemical Phenomena; Chemistry, Physical; Cyclodextrins; Drug Synergism; Kinetics; Lipid Metabolism; Lipids; Mathematical Computing; Naphthalenes; Solubility; Water

1996
Antimutagenic effect of methanolic extracts from peanut hulls.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxin B1; Animals; Antimutagenic Agents; Arachis; Benzo(a)pyrene; Carbolines; Imidazoles; Male; Methanol; Mutagenicity Tests; Mutagens; Plant Extracts; Quinolines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium

1996
Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens.
    Mutagenesis, 1997, Volume: 12, Issue:2

    Topics: Aflatoxin B1; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrene Hydroxylase; Cells, Cultured; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Microsomes; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens; Oxazines; Recombinant Proteins; Steroid Hydroxylases; Substrate Specificity; Transfection

1997
Dietary restriction modulated carcinogen-DNA adduct formation and the carcinogen-induced DNA strand breaks.
    Toxicology letters, 1997, Jun-16, Volume: 92, Issue:1

    Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Chrysenes; DNA Adducts; DNA Damage; Food Deprivation; Kidney; Liver; Male; Mice; Microsomes, Liver; Mutagens; Nitroreductases; Rats

1997
Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.
    Mutagenesis, 1998, Volume: 13, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxin B1; Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A2; Escherichia coli; Gene Expression Regulation, Bacterial; Humans; Mutagenicity Tests; Quinolines; Rats; Recombinant Fusion Proteins

1998
Effects of neem flowers, Thai and Chinese bitter gourd fruits and sweet basil leaves on hepatic monooxygenases and glutathione S-transferase activities, and in vitro metabolic activation of chemical carcinogens in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:6

    Topics: Aflatoxin B1; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animal Feed; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Biotransformation; Carcinogens; China; Cytochrome P-450 Enzyme System; Enzyme Induction; Fruit; Glutathione Transferase; Liver; Male; Microsomes, Liver; Ocimum basilicum; Rats; Rats, Wistar; Thailand; Toxicity Tests; Vegetables

1998
Effects of aflatoxin B1 on the hepatic microsomal mixed function oxidase system during phenobarbital and benzo(a)pyrene treatment in chickens.
    Veterinary and human toxicology, 1999, Volume: 41, Issue:4

    Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Chickens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Induction; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Steroid Hydroxylases

1999
Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens.
    Teratogenesis, carcinogenesis, and mutagenesis, 1999, Volume: 19, Issue:6

    Topics: Aflatoxin B1; Antimutagenic Agents; Bee Venoms; Benzo(a)pyrene; Brazil; Daunorubicin; Mutagenicity Tests; Mutagens; Phenylenediamines; Propolis; Salmonella typhimurium

1999
In vitro inhibition of carcinogen-induced mutagenicity by Cassia occidentalis and Emblica officinalis.
    Drug and chemical toxicology, 2000, Volume: 23, Issue:3

    Topics: Aflatoxin B1; Antimutagenic Agents; Benzo(a)pyrene; Carcinogens; Cassia; Euphorbiaceae; Microsomes, Liver; Mutagenicity Tests; Mutagens; Plant Extracts; Plants, Medicinal; Salmonella typhimurium

2000
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450.
    Mutation research, 2001, Aug-08, Volume: 479, Issue:1-2

    Topics: Aflatoxin B1; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Beverages; Carcinogens; Catechin; Cell Membrane; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Kinetics; Mixed Function Oxygenases; Mutagenesis; NADPH-Ferrihemoprotein Reductase; Protein Binding; Salmonella typhimurium

2001
Protective effects of baicalein and wogonin against benzo[a]pyrene- and aflatoxin B(1)-induced genotoxicities.
    Biochemical pharmacology, 2001, Dec-15, Volume: 62, Issue:12

    Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Diet; Drug Interactions; Flavanones; Flavonoids; Hydroxylation; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mutagenicity Tests; NADPH-Ferrihemoprotein Reductase; Protective Agents

2001
Anti-mutagenic activity of Phyllanthus amarus Schum & Thonn in vitro as well as in vivo.
    Teratogenesis, carcinogenesis, and mutagenesis, 2002, Volume: 22, Issue:4

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Biotransformation; Drug Evaluation, Preclinical; In Vitro Techniques; Male; Methanol; Methylnitronitrosoguanidine; Phenylenediamines; Phyllanthus; Plant Extracts; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Salmonella typhimurium; Sodium Azide; Solvents; Urine

2002
[Study of mutagenesis of two procarcinogens in human amnion cells using a shuttle vector pWB1].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1999, Volume: 30, Issue:2

    Topics: Aflatoxin B1; Amnion; Benzo(a)pyrene; Genes, Suppressor; Genetic Vectors; Humans; Mutagenesis; Mutagens; Plasmids; RNA, Transfer

1999
Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.
    Mutation research, 2002, Oct-31, Volume: 508, Issue:1-2

    Topics: Aflatoxin B1; Anthraquinones; Antimutagenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carmine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Escherichia coli; Humans; Mutagens; Quinoxalines; Recombinant Proteins; Salmonella typhimurium

2002
Infection of rats with Taenia taeniformis metacestodes increases hepatic CYP450, induces the activity of CYP1A1, CYP2B1 and COH isoforms and increases the genotoxicity of the procarcinogens benzo[a]pyrene, cyclophosphamide and aflatoxin B(1).
    Mutagenesis, 2003, Volume: 18, Issue:2

    Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Cats; Cyclophosphamide; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B1; Female; Immunoblotting; Liver; Microsomes, Liver; Mixed Function Oxygenases; Mutagens; Nitrophenols; Protein Isoforms; Rats; Rats, Sprague-Dawley; Reticulocytes; Taenia; Time Factors

2003
Investigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimurium.
    Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:3

    Topics: Aflatoxin B1; Animals; Anti-Bacterial Agents; Antimutagenic Agents; Asteraceae; Benzo(a)pyrene; Chlorophyll; Chromatography, Thin Layer; Daunorubicin; DNA Damage; Dose-Response Relationship, Drug; Flowers; Mutagenicity Tests; Mutagens; Mutation; Plant Extracts; Rats; Salmonella typhimurium; Triterpenes

2006
Effects of chemical carcinogens and physicochemical factors on the UV spectrophotometric determination of DNA.
    Journal of toxicology and environmental health. Part A, 2005, Dec-10, Volume: 68, Issue:23-24

    Topics: Aflatoxin B1; Base Composition; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chloroform; DNA; Ethanol; Hydrogen-Ion Concentration; Nucleosides; Nucleotides; Pentanols; Phenol; Proteins; RNA; Spectrophotometry, Ultraviolet; Temperature

2005
Development of human cell models for assessing the carcinogenic potential of chemicals.
    Toxicology and applied pharmacology, 2008, Nov-01, Volume: 232, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Benzo(a)pyrene; Bronchi; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytochrome P-450 CYP1A1; Genes, myc; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Nickel

2008
Evaluation of the genotoxic and anti-genotoxic activities of silybin in human hepatoma cells (HepG2).
    Mutagenesis, 2010, Volume: 25, Issue:3

    Topics: Aflatoxin B1; Benzo(a)pyrene; Bleomycin; Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell Line, Tumor; DNA; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endonucleases; Escherichia coli Proteins; Humans; Intracellular Space; Liver Neoplasms; Micronuclei, Chromosome-Defective; Mutagens; Reactive Oxygen Species; Silybin; Silymarin

2010
Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Aflatoxin B1; Animal Testing Alternatives; Animals; Benzo(a)pyrene; Biotransformation; Caenorhabditis elegans; Cytochrome P-450 Enzyme System; DNA; DNA Damage; DNA Repair; Mutagens; Phylogeny; Species Specificity

2010
Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Acetaldehyde; Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Fibroblasts; Humans; Mutagens; Mutation; Neoplasms; Tumor Suppressor Protein p53

2012
A co-culture system of human intestinal Caco-2 cells and lymphoblastoid TK6 cells for investigating the genotoxicity of oral compounds.
    Mutagenesis, 2012, Volume: 27, Issue:6

    Topics: Aflatoxin B1; Benzo(a)pyrene; Biotransformation; Caco-2 Cells; Cell Line; Coculture Techniques; Comet Assay; DNA Damage; Humans; Methyl Methanesulfonate; Micronucleus Tests; Mutagens

2012
Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:7

    Topics: Adult; Aflatoxin B1; Animal Use Alternatives; Benzo(a)pyrene; Biliary Tract; Biotransformation; Cell Line, Tumor; Cells, Cultured; Child; Epithelium; Female; Gene Expression Profiling; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Infant; Male; Mutagens; Principal Component Analysis; Reproducibility of Results; Toxicogenetics

2013
Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices.
    Toxicology, 2014, Sep-02, Volume: 323

    Topics: Acetaminophen; Aflatoxin B1; Benzo(a)pyrene; Cell Survival; Comet Assay; Cytochrome P-450 Enzyme System; DNA Damage; Fluorenes; Gene Expression; Glutathione Transferase; Humans; L-Lactate Dehydrogenase; Liver; NAD(P)H Dehydrogenase (Quinone); Xenobiotics

2014
Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:6

    Topics: Activation, Metabolic; Aflatoxin B1; Animals; Apoptosis; Benzo(a)pyrene; Cell Line; Cell Survival; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Profiling; Genetic Markers; Humans; Micronucleus Tests; Mutagens; Phenobarbital; Rats; Reproducibility of Results; Toxicogenetics

2015
Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells.
    Mutagenesis, 2016, Volume: 31, Issue:1

    Topics: Aflatoxin B1; Benzo(a)pyrene; Cell Line, Tumor; Comet Assay; DNA; DNA Damage; Endosulfan; Hep G2 Cells; Histones; Humans; Micronucleus Tests; Mutagenicity Tests; Mutagens; Phosphorylation; Pyrazoles

2016
MicroRNA Responses to the Genotoxic Carcinogens Aflatoxin B1 and Benzo[a]pyrene in Human HepaRG Cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 149, Issue:2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Hepatocyte Nuclear Factor 4; Humans; Liver Neoplasms; MicroRNAs

2016
Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics.
    Toxicology, 2017, 09-01, Volume: 390

    Topics: Aflatoxin B1; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Comet Assay; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 CYP1A1; DNA Damage; DNA Repair; DNA-Binding Proteins; Gene Expression Profiling; Hep G2 Cells; Hepatocytes; Histones; Humans; Phosphorylation; Proteomics; Receptors, Aryl Hydrocarbon; RNA Interference; Time Factors; Transcription Factors; Transcriptome; Transfection; Tumor Suppressor Protein p53

2017
Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?
    Archives of toxicology, 2018, Volume: 92, Issue:2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Cell Line, Tumor; Dimethylnitrosamine; Humans; Hydrogen Peroxide; Imidazoles; Inactivation, Metabolic; Liver; Mutagenicity Tests; Mutagens; Quinolines; Reactive Oxygen Species; Tumor Suppressor Protein p53

2018
Adipose tissue stem cell-derived hepatic progenies as an in vitro model for genotoxicity testing.
    Archives of toxicology, 2018, Volume: 92, Issue:5

    Topics: Adipose Tissue; Aflatoxin B1; Benzo(a)pyrene; Cell Differentiation; Cell Line; Comet Assay; Enzymes; Female; Hep G2 Cells; Humans; Imidazoles; Liver; Mesenchymal Stem Cells; Mutagenicity Tests

2018
Effect of aflatoxin B
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 121

    Topics: Aflatoxin B1; Benzo(a)pyrene; Cell Line; DNA Adducts; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Hepatocytes; Humans; Methapyrilene; Nucleic Acid Amplification Techniques; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Transcription, Genetic; Transcriptome

2018
An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests.
    Mutagenesis, 2019, 05-29, Volume: 34, Issue:2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Cells, Cultured; Comet Assay; Cyclophosphamide; Cytochrome P-450 Enzyme System; Diethylnitrosamine; DNA Damage; Fluorenes; Hepatocytes; Humans; Karyotype; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens

2019
The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, Jun-01, Volume: 169, Issue:2

    Topics: Activation, Metabolic; Aflatoxin B1; Benchmarking; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Hepatocytes; High-Throughput Nucleotide Sequencing; Humans; Transcriptome

2019
Micronuclei Formation by Promutagens in Metabolism-Incompetent V79 Cells Interacting With Activation-Proficient Cells in Various Experimental Settings.
    Environmental and molecular mutagenesis, 2020, Volume: 61, Issue:2

    Topics: Aflatoxin B1; Animals; Arylsulfotransferase; Benzo(a)pyrene; Cell Line; Cricetinae; Cytochrome P-450 Enzyme System; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pyrenes

2020
Derivation of metabolic point of departure using high-throughput in vitro metabolomics: investigating the importance of sampling time points on benchmark concentration values in the HepaRG cell line.
    Archives of toxicology, 2023, Volume: 97, Issue:3

    Topics: Aflatoxin B1; Benchmarking; Benzo(a)pyrene; Cell Line; Cyclosporine; Lipids; Metabolomics; Rotenone

2023
Cuproptosis-related gene identification and immune infiltration analysis in systemic lupus erythematosus.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Aflatoxin B1; Apoptosis; Autoimmune Diseases; Benzo(a)pyrene; Copper; Humans; Lupus Erythematosus, Systemic; MicroRNAs; Molecular Docking Simulation

2023