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aflatoxin b1 and 2,3-dihydro-2-(n(7)-guanyl)-3-hydroxyaflatoxin b1

aflatoxin b1 has been researched along with 2,3-dihydro-2-(n(7)-guanyl)-3-hydroxyaflatoxin b1 in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's11 (40.74)18.2507
2000's8 (29.63)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Donahue, PR; Groopman, JD; Hasler, JA; Pikul, A; Trudel, LJ; Wogan, GN1
DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A1
Johnson, RL; Shaulsky, G; Shockcor, JP; Stark, AA; Taylor, LC1
Davidson, NE; Egner, PA; Groopman, JD; Kensler, TW; Pikul, A; Roebuck, BD1
Autrup, H; Seremet, T; Wakhisi, J; Wasunna, A1
Garner, RC; Smith, JR; Wood, ML1
Autrup, H; Harris, CC; Vahakangas, K; Wakhisi, J; Wasunna, A1
Autrup, H; Bradley, KA; Shamsuddin, AK; Wakhisi, J; Wasunna, A1
Bennett, RA; Essigmann, JM; Wogan, GN1
Chu, FS; Li, YK; Pestka, JJ1
Johnston, DS; Stone, MP2
Groopman, JD; Weaver, VM1
Bailey, EA; Essigmann, JM; Harris, TM; Iyer, RS; Stone, MP1
Chen, CJ; Liaw, YF; Lien, JP; Yu, MW1
Groopman, JD; Kensler, TW1
Chen, CJ; Chiang, YC; Lien, JP; Yu, MW1
Sashidhar, RB; Sujatha, N; Vidyasagar, T1
Campbell, TC; Lange, T; Root, M1
Bhat, RV; Nayak, S; Sashidhar, RB1
Bailey, GS; Egner, PA; Gange, SJ; Groopman, JD; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Qian, GS; Wang, JB; Wu, Y; Zhang, BC; Zhang, QN; Zhu, YR1
Essigmann, JM; Hamm, ML; Harris, CM; Harris, TM; Henderson, PT; Smela, ME1
Giri, I; Stone, MP1
El-Nezami, H; Juvonen, RO; Kemiläinen, H; Ling, W; Ma, J; Mykkänen, H; Mykkänen, O; Polychronaki, N; Salminen, E; Salminen, S; Zhu, H1
Alessi, M; Bedard, LL; Davey, S; Massey, TE1
El-Nezami, HS; Juvonen, RO; Ling, W; Ma, J; Mykkänen, HM; Polychronaki, NN; Poussa, T; Salminen, EK; Salminen, SJ; Zhu, H1
Baptista, GZ; Jager, AV; Oliveira, CA; Souto, PC; Tonin, FG1

Reviews

1 review(s) available for aflatoxin b1 and 2,3-dihydro-2-(n(7)-guanyl)-3-hydroxyaflatoxin b1

ArticleYear
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 25

    Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes

1996

Trials

2 trial(s) available for aflatoxin b1 and 2,3-dihydro-2-(n(7)-guanyl)-3-hydroxyaflatoxin b1

ArticleYear
Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Animals; Biomarkers; Carcinoma, Hepatocellular; China; Chlorophyllides; DNA Adducts; Female; Food Contamination; Guanine; Humans; Liver Neoplasms; Male; Middle Aged; Risk Factors

2001
Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:5

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; China; DNA Adducts; Double-Blind Method; Guanine; Humans; Lacticaseibacillus rhamnosus; Liver Neoplasms; Placebos; Probiotics; Propionibacterium; Risk Factors

2006

Other Studies

24 other study(ies) available for aflatoxin b1 and 2,3-dihydro-2-(n(7)-guanyl)-3-hydroxyaflatoxin b1

ArticleYear
Molecular dosimetry in rat urine of aflatoxin-N7-guanine and other aflatoxin metabolites by multiple monoclonal antibody affinity chromatography and immunoaffinity/high performance liquid chromatography.
    Cancer research, 1992, Jan-15, Volume: 52, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antibody Affinity; Chromatography, Affinity; Chromatography, High Pressure Liquid; Guanine; Rats; Regression Analysis

1992
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
    Carcinogenesis, 1992, Volume: 13, Issue:1

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes

1992
Properties of aflatoxin-DNA adducts formed by photoactivation and characterization of the major photoadduct as aflatoxin-N7-guanine.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes; Photochemistry; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Ultraviolet Rays

1990
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Enzyme Induction; Ethoxyquin; gamma-Glutamyltransferase; Glutathione Transferase; Guanine; Liver; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344

1986
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
    Cancer research, 1987, Jul-01, Volume: 47, Issue:13

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; DNA Damage; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Kenya; Liver Neoplasms; Male; Sex Factors

1987
Structural characterization of the major adducts obtained after reaction of an ultimate carcinogen aflatoxin B1-dichloride with calf thymus DNA in vitro.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Thymus Gland

1988
Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Age Factors; Child; Environmental Exposure; Female; Geography; Guanine; Humans; Kenya; Male; Middle Aged; Sex Factors

1985
Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya.
    Carcinogenesis, 1983, Volume: 4, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Biotransformation; Guanine; Humans; Kenya; Spectrometry, Fluorescence

1983
Excretion of an aflatoxin-guanine adduct in the urine of aflatoxin B1-treated rats.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guanine; Rats

1981
Reactivity of aflatoxin B2a antibody with aflatoxin B1-modified DNA and related metabolites.
    Applied and environmental microbiology, 1982, Volume: 44, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Antibodies; Antibody Specificity; Cross Reactions; DNA; Enzyme-Linked Immunosorbent Assay; Guanine

1982
Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR.
    Biochemistry, 1995, Oct-31, Volume: 34, Issue:43

    Topics: Aflatoxin B1; Base Sequence; Dinucleoside Phosphates; DNA; DNA Adducts; Guanine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons; Solutions

1995
Fluorescence quantification of aflatoxin N7-guanine adducts.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:8

    Topics: Aflatoxin B1; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Hydrolysis; Male; Rats; Rats, Inbred F344; Spectrometry, X-Ray Emission

1994
Mutational properties of the primary aflatoxin B1-DNA adduct.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-20, Volume: 93, Issue:4

    Topics: Aflatoxin B1; Bacteriophage M13; Base Sequence; Carcinoma, Hepatocellular; DNA Adducts; DNA, Viral; Escherichia coli; Guanine; Humans; Liver Neoplasms; Models, Molecular; Molecular Sequence Data; Mutagenesis; SOS Response, Genetics; Structure-Activity Relationship

1996
Effects of multiple risk factors for hepatocellular carcinoma on formation of aflatoxin B1-DNA adducts.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:8

    Topics: Aflatoxin B1; Age Factors; Alcohol Drinking; Biomarkers; Carcinogens; Carcinoma, Hepatocellular; Carrier State; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Logistic Models; Male; Multivariate Analysis; Prospective Studies; Risk Factors; Smoking; Taiwan

1996
Plasma antioxidant vitamins, chronic hepatitis B virus infection and urinary aflatoxin B1-DNA adducts in healthy males.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Adult; Aflatoxin B1; Aged; Antioxidants; beta Carotene; Carotenoids; Chronic Disease; DNA; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Testosterone; Vitamin E; Vitamins

1997
Direct synthesis of aflatoxin B1-N7 guanine adduct: a reference standard for biological monitoring of dietary aflatoxin exposure in molecular epidemiological studies.
    Food additives and contaminants, 1997, Volume: 14, Issue:5

    Topics: Aflatoxin B1; Chlorobenzoates; Chromatography, High Pressure Liquid; Food Analysis; Guanine; Reference Standards

1997
Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver.
    Chemico-biological interactions, 1997, Oct-24, Volume: 106, Issue:3

    Topics: Administration, Oral; Aflatoxin B1; Animals; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344

1997
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I.
    Chemical research in toxicology, 2000, Volume: 13, Issue:11

    Topics: Aflatoxin B1; DNA; DNA Adducts; DNA Polymerase I; DNA Replication; Exonucleases; Guanine; Oligonucleotides; Templates, Genetic

2000
Quantification and validation of enzyme immunoassay for urinary aflatoxin B1-N7-guanine adduct for biological monitoring of aflatoxins.
    The Analyst, 2001, Volume: 126, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA Adducts; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Female; Food Contamination; Guanine; Humans; Male; Rabbits; Rats; Rats, Inbred F344

2001
The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, May-14, Volume: 99, Issue:10

    Topics: Aflatoxin B1; Bacteriophage M13; Carcinoma, Hepatocellular; DNA Adducts; DNA, Neoplasm; DNA, Viral; Guanine; Humans; Liver Neoplasms; Molecular Structure; Mutagenesis; Mutagens; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Wobble dC.dA pairing 5' to the cationic guanine N7 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 adduct: implications for nontargeted AFB1 mutagenesis.
    Biochemistry, 2003, Jun-17, Volume: 42, Issue:23

    Topics: Aflatoxin B1; Base Composition; Base Pair Mismatch; Base Sequence; Cations; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Protons; Structure-Activity Relationship

2003
Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males.
    International journal of cancer, 2005, Jul-20, Volume: 115, Issue:6

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; China; Feces; Guanine; Hepatitis B; Humans; Male

2005
Susceptibility to aflatoxin B1-induced carcinogenesis correlates with tissue-specific differences in DNA repair activity in mouse and in rat.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; DNA; DNA Repair; Female; Genetic Predisposition to Disease; Guanine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Mice; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity

2005
Assessment of aflatoxin exposure using serum and urinary biomarkers in São Paulo, Brazil: A pilot study.
    International journal of hygiene and environmental health, 2016, Volume: 219, Issue:3

    Topics: Adult; Aflatoxin B1; Aflatoxin M1; Arachis; Biomarkers; Brazil; Dairy Products; Diet; Environmental Monitoring; Food Contamination; Guanine; Humans; Lysine; Middle Aged; Pilot Projects; Zea mays

2016