aflastatin-a and ketene

aflastatin-a has been researched along with ketene* in 1 studies

Other Studies

1 other study(ies) available for aflastatin-a and ketene

Article	Year
Synthesis of C3-C21 Segment of Aflastatin A Using Remote Asymmetric Induction Reactions. Organic letters, 2019, 02-01, Volume: 21, Issue:3 The C3-C21 segment of aflastatin A has been synthesized by converging three segments including the C3-C8 segment, the C9-C15 segment, and the C16-C21 segment. Each segment has been synthesized from a vinylketene silyl N,O-acetal possessing a chiral auxiliary by a wide-range stereocontrol strategy. The C3-C8 segment was constructed in seven steps including the stereoselective vinylogous Mukaiyama alkylation, while the C9-C15 segment and the C16-C21 segment were synthesized using the vinylogous Mukaiyama aldol reaction in seven and eight steps, respectively. Topics: Chemistry Techniques, Synthetic; Ethylenes; Ketones; Pyrrolidinones; Stereoisomerism	2019

Article

Year

Synthesis of C3-C21 Segment of Aflastatin A Using Remote Asymmetric Induction Reactions.

Organic letters, 2019, 02-01, Volume: 21, Issue:3

The C3-C21 segment of aflastatin A has been synthesized by converging three segments including the C3-C8 segment, the C9-C15 segment, and the C16-C21 segment. Each segment has been synthesized from a vinylketene silyl N,O-acetal possessing a chiral auxiliary by a wide-range stereocontrol strategy. The C3-C8 segment was constructed in seven steps including the stereoselective vinylogous Mukaiyama alkylation, while the C9-C15 segment and the C16-C21 segment were synthesized using the vinylogous Mukaiyama aldol reaction in seven and eight steps, respectively.

Topics: Chemistry Techniques, Synthetic; Ethylenes; Ketones; Pyrrolidinones; Stereoisomerism

2019