aflastatin-a and ketene
aflastatin-a has been researched along with ketene* in 1 studies
Other Studies
1 other study(ies) available for aflastatin-a and ketene
| Article | Year |
|---|---|
Synthesis of C3-C21 Segment of Aflastatin A Using Remote Asymmetric Induction Reactions.
The C3-C21 segment of aflastatin A has been synthesized by converging three segments including the C3-C8 segment, the C9-C15 segment, and the C16-C21 segment. Each segment has been synthesized from a vinylketene silyl N,O-acetal possessing a chiral auxiliary by a wide-range stereocontrol strategy. The C3-C8 segment was constructed in seven steps including the stereoselective vinylogous Mukaiyama alkylation, while the C9-C15 segment and the C16-C21 segment were synthesized using the vinylogous Mukaiyama aldol reaction in seven and eight steps, respectively. Topics: Chemistry Techniques, Synthetic; Ethylenes; Ketones; Pyrrolidinones; Stereoisomerism | 2019 |