afdx 384 has been researched along with oxotremorine in 6 studies
| Studies (afdx 384) | Trials (afdx 384) | Recent Studies (post-2010) (afdx 384) | Studies (oxotremorine) | Trials (oxotremorine) | Recent Studies (post-2010) (oxotremorine) |
|---|---|---|---|---|---|
| 78 | 0 | 6 | 1,930 | 6 | 99 |
| 5 | 0 | 0 | 1,930 | 6 | 99 |
| Protein | Taxonomy | afdx 384 (IC50) | oxotremorine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.4 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 5 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 2.321 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 8 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.5012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Wells, JW; Wreggett, KA | 1 |
| Araujo, DM; Hefti, F; Lapchak, PA | 1 |
| Auld, DS; Day, JC; Mennicken, F; Quirion, R | 1 |
| Dean, B; Gibbons, AS; Jeon, WJ; Scarr, E | 1 |
| Casida, JE; Honda, H; Tomizawa, M | 1 |
6 other study(ies) available for afdx 384 and oxotremorine
| Article | Year |
|---|---|
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors.
Topics: Allosteric Regulation; Animals; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Molecular Weight; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Sarcolemma; Scopolamine Derivatives; Swine | 1995 |
Regulation of hippocampal muscarinic receptor function by chronic nerve growth factor treatment in adult rats with fimbrial transections.
Topics: Animals; Autoradiography; Female; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Inosine Triphosphate; Nerve Growth Factors; Oxotremorine; Parasympathetic Nervous System; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Pharmacological characterization of endogenous acetylcholine release from primary septal cultures.
Topics: Acetylcholine; Animals; Cells, Cultured; Choline; Choline O-Acetyltransferase; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Muscarinic Agonists; Neuromuscular Depolarizing Agents; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Rats; Septum of Brain; Time Factors; Veratridine | 2000 |
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Disorder, Major; Disease Models, Animal; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Muscarinic Agonists; Oxotremorine; Pirenzepine; Radiopharmaceuticals; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Tritium | 2016 |
Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists.
Topics: Animals; Brain; Drosophila; Houseflies; Insecta; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 2007 |