afdx 384 has been researched along with methoctramine in 6 studies
| Studies (afdx 384) | Trials (afdx 384) | Recent Studies (post-2010) (afdx 384) | Studies (methoctramine) | Trials (methoctramine) | Recent Studies (post-2010) (methoctramine) |
|---|---|---|---|---|---|
| 78 | 0 | 6 | 332 | 1 | 32 |
| 5 | 0 | 0 | 40 | 0 | 15 |
| 5 | 0 | 0 | 332 | 1 | 32 |
| Protein | Taxonomy | afdx 384 (IC50) | methoctramine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 0.9772 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0407 | |
| Acetylcholinesterase | Homo sapiens (human) | 5.3703 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.138 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.138 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 0.9772 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lau, WM; Szilagyi, M | 2 |
| Pepeu, G; Vannucchi, MG | 1 |
| Avignone, E; Cattaneo, A; Cherubini, E; Guarnieri, E; Rosati, AM; Traversa, U | 1 |
| Brann, MR; Dörje, F; Lambrecht, G; Mutschler, E; Tacke, R; Wess, J | 1 |
| Casida, JE; Honda, H; Tomizawa, M | 1 |
6 other study(ies) available for afdx 384 and methoctramine
| Article | Year |
|---|---|
A pharmacological profile of glycopyrrolate: interactions at the muscarinic acetylcholine receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Binding, Competitive; Carbachol; Diamines; Female; Gallamine Triethiodide; Glycopyrrolate; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Myocardial Contraction; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate | 1992 |
Muscarinic receptor modulation of acetylcholine release from rat cerebral cortex and hippocampus.
Topics: Acetylcholine; Animals; Cerebral Cortex; Diamines; Hippocampus; Male; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine | 1995 |
Interaction of tacrine at M1 and M2 cholinoceptors in guinea pig brain.
Topics: Animals; Binding Sites; Brain; Diamines; Drug Interactions; Female; Guinea Pigs; Parasympatholytics; Pirenzepine; Receptors, Cholinergic; Tacrine | 1993 |
Increased density of M1 receptors in the hippocampus of juvenile rats chronically deprived of NGF.
Topics: Animals; Animals, Newborn; Binding, Competitive; Diamines; Hippocampus; Neoplasm Transplantation; Nerve Growth Factors; Pirenzepine; Protein Binding; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Tumor Cells, Cultured | 1999 |
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
Topics: Animals; Cells, Cultured; Cricetinae; Humans; N-Methylscopolamine; Parasympatholytics; Receptors, Muscarinic; Scopolamine Derivatives; Transfection | 1991 |
Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists.
Topics: Animals; Brain; Drosophila; Houseflies; Insecta; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 2007 |