Compounds > afdx 384

Page last updated: 2024-09-03

afdx 384 and hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide)

afdx 384 has been researched along with hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide) in 3 studies

Compound Research Comparison

Studies (afdx 384)	Trials (afdx 384)	Recent Studies (post-2010) (afdx 384)	Studies (hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide))	Trials (hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide))	Recent Studies (post-2010) (hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide))
78	0	6	24	0	3

Protein Interaction Comparison

Protein	Taxonomy	afdx 384 (IC50)	hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide) (IC50)
Muscarinic acetylcholine receptor M2	Homo sapiens (human)		0.4786

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andresen, I; Lambrecht, G; Mohr, K; Tränkle, C	1
Ataie, A; Heller, E; Holzgrabe, U; Mohr, K; Mohr, M	1
De Amici, M; Holzgrabe, U; Mohr, K	1

Other Studies

3 other study(ies) available for afdx 384 and hexamethylenebis(dimethyl-(3-phthalimidopropyl)ammonium bromide)

Article	Year
M2 receptor binding of the selective antagonist AF-DX 384: possible involvement of the common allosteric site. Molecular pharmacology, 1998, Volume: 53, Issue:2 Topics: Allosteric Regulation; Animals; Binding Sites; Cell Membrane; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoindoles; Male; Myocardial Contraction; Myocardium; Parasympatholytics; Phthalimides; Pirenzepine; Rabbits; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic; Vas Deferens	1998
Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84. Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12 Topics: Allosteric Regulation; Animals; Guinea Pigs; In Vitro Techniques; Isoindoles; Muscarinic Antagonists; Myocardium; Phthalimides; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Swine	2004
Allosteric modulators and selective agonists of muscarinic receptors. Journal of molecular neuroscience : MN, 2006, Volume: 30, Issue:1-2 Topics: Allosteric Regulation; Animals; Cholinergic Agents; Isoindoles; Muscarinic Agonists; Parasympatholytics; Phthalimides; Pirenzepine; Receptors, Muscarinic	2006