afdx 116 has been researched along with oxotremorine in 43 studies
| Studies (afdx 116) | Trials (afdx 116) | Recent Studies (post-2010) (afdx 116) | Studies (oxotremorine) | Trials (oxotremorine) | Recent Studies (post-2010) (oxotremorine) |
|---|---|---|---|---|---|
| 367 | 1 | 24 | 1,930 | 6 | 99 |
| Protein | Taxonomy | afdx 116 (IC50) | oxotremorine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.4 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 5 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 2.321 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 8 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.7261 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.5012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.60) | 18.7374 |
| 1990's | 28 (65.12) | 18.2507 |
| 2000's | 7 (16.28) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovacs, I; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Casida, JE; Honda, H; Tomizawa, M | 1 |
| Crino, PB; Jensen, EL; Vogt, BA | 1 |
| Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK | 1 |
| Gies, JP; Haddad, EB; Landry, Y | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Inoue, M; Kuriyama, H | 1 |
| Boddeke, HW | 1 |
| Richards, MH | 1 |
| Bird, ED; Crino, PB; Plager, MD; Vogt, BA | 1 |
| Borkowski, JA; Buck, MA; Mallon, RG; McQuade, RD; Pai, JK; Pepitoni, S | 1 |
| Danilo, P; Rosen, MR; Steinberg, SF | 1 |
| Costi, A; Marchi, M; Raiteri, M; Volpe, G | 1 |
| Delen, FM; Ehlert, FJ; Liem, HA; Yun, SH | 1 |
| Bagetta, G; Constanti, A | 1 |
| De Boer, P; Horn, AS; Rollema, H; Westerink, BH; Zaagsma, J | 1 |
| Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC | 1 |
| Marchi, M; Raiteri, M | 1 |
| Kato, T; Mizobe, F; Xu, M; Yamamoto, T | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Quirion, R | 1 |
| Delen, FM; Ehlert, FJ; Friedman, DJ; Self, DW; Yun, SH | 1 |
| Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N | 1 |
| Camus, J; Christophe, J; De Neef, P; Fourmy, D; Pradayrol, L; Robberecht, P; Scemama, JL; Tastenoy, M; Vaysse, N; Waelbroeck, M | 1 |
| Bai, D; Sattelle, DB | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Haass, M; Haunstetter, A; Krüger, C; Kübler, W; Yi, X | 1 |
| Cynader, MS; Drance, SM; Gupta, N; McAllister, R; Rootman, J | 1 |
| Aslan, AN; Oktay, S; Onat, F; Ozkutlu, U | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Ehlert, FJ; Thomas, EA | 1 |
| Matthews, MR; Zaidi, ZF | 1 |
| Ehlert, FJ; Sawyer, GW | 2 |
| Islam, MA; Kimura, I; Nojima, H | 1 |
| Ehlert, FJ; Ostrom, RS | 1 |
| DeLapp, NW; Falcone, J; Felder, CC; McClure, D; McKinzie, JH; Sawyer, BD; Vandergriff, A | 1 |
| Höhle, KD; Möhlig, T; Reinheimer, T; Wessler, I; Zimmermann, S | 1 |
| Hosoi, T; Nomura, J; Nomura, Y; Okuma, Y | 1 |
| Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Mohler, EG; Palencia, CA; Prior, M; Ragozzino, ME; Rozman, S | 1 |
| Blackstone, K; Pratt, WE | 1 |
2 review(s) available for afdx 116 and oxotremorine
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
Cardioselective muscarinic antagonists.
Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
41 other study(ies) available for afdx 116 and oxotremorine
| Article | Year |
|---|---|
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line.
Topics: Amino Acid Sequence; Animals; Carbachol; Cloning, Molecular; Cyclic AMP; Humans; Mice; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Muscarinic; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity | 1998 |
Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists.
Topics: Animals; Brain; Drosophila; Houseflies; Insecta; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 2007 |
Multiple heteroreceptors on limbic thalamic axons: M2 acetylcholine, serotonin1B, beta 2-adrenoceptors, mu-opioid, and neurotensin.
Topics: Atenolol; Autoradiography; Axons; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethanolamines; Limbic System; Neurotensin; Oxotremorine; Pindolol; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Neurotensin; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Receptors, Serotonin; Thalamus; Tritium | 1992 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallamine Triethiodide; Inflammation; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1991 |
Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Sialic Acids | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Muscarinic receptor is coupled with a cation channel through a GTP-binding protein in guinea-pig chromaffin cells.
Topics: Adrenal Medulla; Animals; Barium; Calcium; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Guinea Pigs; Ion Channels; Male; Membrane Potentials; Muscarine; Oxotremorine; Pirenzepine; Receptors, Muscarinic; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Different effects of muscarinic agonists in rat superior cervical ganglion and hippocampal slices.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Ganglia, Sympathetic; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Parasympathomimetics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains | 1991 |
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Autoradiography; Cerebral Cortex; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Humans; Iodocyanopindolol; Ketanserin; Male; Middle Aged; Oxotremorine; Paroxetine; Pindolol; Piperidines; Pirenzepine; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
Phospholipase D activity and phosphatidylethanol formation in stimulated HeLa cells expressing the human m1 muscarinic acetylcholine receptor gene.
Topics: Cloning, Molecular; Enzyme Activation; Genetic Vectors; Glycerophospholipids; HeLa Cells; Humans; Kinetics; Myristic Acid; Myristic Acids; Oxotremorine; Parasympatholytics; Phosphatidic Acids; Phospholipase D; Pirenzepine; Plasmids; Quinuclidinyl Benzilate; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Developmental changes in the muscarinic stimulation of canine Purkinje fibers.
Topics: Acetylcholine; Age Factors; Animals; Dogs; Female; GTP-Binding Proteins; Heart Conduction System; In Vitro Techniques; Male; Membrane Potentials; Oxotremorine; Pertussis Toxin; Pirenzepine; Purkinje Fibers; Receptors, Muscarinic; Virulence Factors, Bordetella | 1990 |
Endogenous aspartate release in the rat hippocampus is inhibited by M2 'cardiac' muscarinic receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Calcium; Carbachol; Chromatography, High Pressure Liquid; Heart; Hippocampus; In Vitro Techniques; Male; Myocardium; Neuromuscular Depolarizing Agents; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart.
Topics: Adenylyl Cyclase Inhibitors; Amitriptyline; Animals; Brain; Doxepin; Heart; Imipramine; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Muscarinic suppression of the evoked N-wave by oxotremorine-M recorded in the guinea-pig olfactory cortex slice.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Diamines; Electric Stimulation; Electroencephalography; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic | 1990 |
An M3-like muscarinic autoreceptor regulates the in vivo release of acetylcholine in rat striatum.
Topics: Acetylcholine; Animals; Atropine; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dose-Response Relationship, Drug; Male; Neostigmine; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors | 1990 |
Regulation of histamine release and synthesis in the brain by muscarinic receptors.
Topics: Animals; Brain; Carbachol; Histamine Release; Male; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Interaction acetylcholine-glutamate in rat hippocampus: involvement of two subtypes of M-2 muscarinic receptors.
Topics: Acetylcholine; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1989 |
Differential effects of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism in freely moving rats.
Topics: Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thiophenes | 1989 |
Binding sites for [3H]AF-DX 116 and effect of AF-DX 116 on endogenous acetylcholine release from rat brain slices.
Topics: Acetylcholine; Animals; Brain; In Vitro Techniques; Male; Oxotremorine; Parasympathomimetics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1989 |
Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives | 1989 |
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Characterization of muscarinic receptors in human pancreatic membranes.
Topics: Carbachol; Cell Membrane; Humans; Oxotremorine; Pancreas; Pilocarpine; Pirenzepine; Receptors, Muscarinic | 1988 |
Muscarinic acetylcholine receptors on an identified motor neurone in the cockroach, Periplaneta americana.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Atropine; Dose-Response Relationship, Drug; Evoked Potentials; Ganglia, Invertebrate; In Vitro Techniques; Male; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Periplaneta; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Vertebrates | 1994 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischemia and reperfusion.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Neuropeptide Y; Norepinephrine; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1994 |
Muscarinic receptor M1 and M2 subtypes in the human eye: QNB, pirenzipine, oxotremorine, and AFDX-116 in vitro autoradiography.
Topics: Adult; Aged; Aged, 80 and over; Anterior Eye Segment; Autoradiography; Ciliary Body; Eye; Female; Humans; Iris; Male; Middle Aged; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Retina | 1994 |
Central muscarinic M2 cholinoceptors involved in cholinergic hypertension.
Topics: Animals; Blood Pressure; Diamines; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Muscarinic Antagonists; Oxotremorine; Physostigmine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Involvement of the M2 muscarinic receptor in contractions of the guinea pig trachea, guinea pig esophagus, and rat fundus.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Esophagus; Gastric Fundus; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Trachea; Virulence Factors, Bordetella | 1996 |
Exocytotic release from neuronal cell bodies, dendrites and nerve terminals in sympathetic ganglia of the rat, and its differential regulation.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Dendrites; Exocytosis; Ganglia, Sympathetic; Male; Membrane Potentials; Nerve Endings; Neurons; Nicotine; Oxotremorine; Parasympatholytics; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Regression Analysis; Synapses | 1997 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1998 |
Muscarinic M1 receptor activation reduces maximum upstroke velocity of action potential in mouse right atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Action Potentials; Animals; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Mice; Microelectrodes; Muscarinic Agonists; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1998 |
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.
Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 1999 |
Muscarinic M3 receptor inactivation reveals a pertussis toxin-sensitive contractile response in the guinea pig colon: evidence for M2/M3 receptor interactions.
Topics: Animals; Colon; Diphenylacetic Acids; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Models, Biological; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1999 |
Determination of [35S]guanosine-5'-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using an anti-G protein scintillation proximity assay.
Topics: Algorithms; Animals; Antibodies; Cell Membrane; CHO Cells; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Oxotremorine; Pirenzepine; Precipitin Tests; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic | 1999 |
Muscarinic control of histamine release from airways. Inhibitory M1-receptors in human bronchi but absence in rat trachea.
Topics: Acetylcholine; Animals; Bronchi; Calcimycin; Clozapine; Female; Histamine Release; Humans; Ionophores; Male; Mast Cells; Muscarinic Antagonists; Organ Culture Techniques; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Species Specificity; Trachea | 2000 |
The presence and functions of muscarinic receptors in human T cells: the involvement in IL-2 and IL-2 receptor system.
Topics: Acetylcholine; Blotting, Northern; DNA; DNA Probes; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-2; Jurkat Cells; Muscarinic Agonists; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Interleukin-2; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes | 2003 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Acetylcholine activity in selective striatal regions supports behavioral flexibility.
Topics: Acetylcholine; Analysis of Variance; Animals; Cognition; Corpus Striatum; Male; Maze Learning; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Pirenzepine; Random Allocation; Rats; Rats, Long-Evans; Receptor, Muscarinic M2; Reversal Learning | 2009 |
Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Nucleus Accumbens; Oxotremorine; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 2009 |