Compounds > afdx 116
Page last updated: 2024-09-02

afdx 116 and neostigmine

afdx 116 has been researched along with neostigmine in 6 studies

Compound Research Comparison

Studies
(afdx 116)		Trials
(afdx 116)		Recent Studies (post-2010)
(afdx 116)		Studies
(neostigmine)		Trials
(neostigmine)		Recent Studies (post-2010) (neostigmine)
3671245,020454637

Protein Interaction Comparison

ProteinTaxonomyafdx 116 (IC50)neostigmine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)2.54
CholinesteraseHomo sapiens (human)0.45
AcetylcholinesteraseHomo sapiens (human)1.1
CholinesteraseEquus caballus (horse)2.93

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Boer, P; Horn, AS; Rollema, H; Westerink, BH; Zaagsma, J1
Bouaziz, H; Eisenach, JC; Tong, C1
Bouaziz, H; Detweiler, DJ; Eisenach, JC; Li, P; Lothe, A; Tong, C; Yoon, Y1
Baratti, CM; Kopf, SR; Opezzo, JW1
Backman, SB; Collier, B; Polosa, C; Stein, RD1
Cohen, ML; Stengel, PW1

Other Studies

6 other study(ies) available for afdx 116 and neostigmine

ArticleYear
An M3-like muscarinic autoreceptor regulates the in vivo release of acetylcholine in rat striatum.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dose-Response Relationship, Drug; Male; Neostigmine; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors

1990
Postoperative analgesia from intrathecal neostigmine in sheep.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:6

    Topics: Analgesia, Epidural; Animals; Female; Neostigmine; Pain Measurement; Pain, Postoperative; Pirenzepine; Receptors, Muscarinic; Sheep

1995
Spinal cholinergic alpha-2 adrenergic interactions in analgesia and hemodynamic control: role of muscarinic receptor subtypes and nitric oxide.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Analgesia; Animals; Clonidine; Female; Hemodynamics; Neostigmine; Nitric Oxide; Pirenzepine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sheep; Spinal Cord

1994
Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116.
    Behavioral and neural biology, 1993, Volume: 60, Issue:1

    Topics: Animals; Atropine; Avoidance Learning; Behavior, Animal; Brain; Drug Synergism; Male; Memory; Mice; Neostigmine; Parasympatholytics; Physostigmine; Pirenzepine; Receptors, Muscarinic

1993
Synaptic inhibitory effects of edrophonium on sympathetic ganglionic transmission.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10

    Topics: Acetylcholinesterase; Action Potentials; Animals; Axons; Cholinesterase Inhibitors; Edrophonium; Evoked Potentials; Muscarinic Antagonists; Neostigmine; Nerve Fibers; Parasympatholytics; Parasympathomimetics; Pirenzepine; Potassium; Presynaptic Terminals; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Synapses; Synaptic Transmission; Tritium

1998
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibitors; Drug Interactions; Gallbladder; Indomethacin; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Neostigmine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic

2002