afdx 116 has been researched along with himbacine in 12 studies
| Studies (afdx 116) | Trials (afdx 116) | Recent Studies (post-2010) (afdx 116) | Studies (himbacine) | Trials (himbacine) | Recent Studies (post-2010) (himbacine) |
|---|---|---|---|---|---|
| 367 | 1 | 24 | 73 | 0 | 9 |
| Protein | Taxonomy | afdx 116 (IC50) | himbacine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0175 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.1144 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 1.016 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.5482 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.3336 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (83.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovacs, I; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Harada, M; Koike, K; Takayanagi, I | 1 |
| Baron, E; Boer, R; Eltze, M; Kromer, W | 1 |
| Bloom, JW; Lai, J; Roeske, WR; Yamamura, HI | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Imaizumi, Y; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Gillman, TA; Mitchelson, F; Pennefather, JN | 1 |
| Andrioli, GC; Cavazzani, P; Marchi, M; Raiteri, M; Russo, C | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Hirose, K; Kaeriyama, S; Muramatsu, A; Nouchi, H; Sato, M; Shigenobu, K; Shimizu, N; Tanaka, H | 1 |
| Barathi, VA; Beuerman, RW; Goh, LK; Kwan, JL; Seet, LF; Tan, QS; Vithana, EN; Weon, SR | 1 |
12 other study(ies) available for afdx 116 and himbacine
| Article | Year |
|---|---|
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line.
Topics: Amino Acid Sequence; Animals; Carbachol; Cloning, Molecular; Cyclic AMP; Humans; Mice; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Muscarinic; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity | 1998 |
Characterization of subtype of propylbenzilylcholine mustard (PrBCM)-sensitive and -resistant muscarinic cholinoceptors in guinea pig ileal muscle.
Topics: 4-Aminopyridine; Alkaloids; Animals; Drug Resistance; Furans; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; Muscle, Smooth; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Sensitivity and Specificity | 1992 |
Telenzepine inhibits electrically-stimulated, acetylcholine plus histamine-mediated acid secretion in the mouse isolated stomach by blockade of M1 muscarine receptors.
Topics: Acetylcholine; Alkaloids; Animals; Anti-Ulcer Agents; Electric Stimulation; Furans; Gastric Acid; Gastric Mucosa; Histamine; Mice; Muscarinic Antagonists; Naphthalenes; p-Methoxy-N-methylphenethylamine; Parasympatholytics; Piperidines; Pirenzepine; Stomach; Thiazepines; Vagus Nerve | 1991 |
Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor.
Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Fibroblasts; Furans; Gene Amplification; Gene Expression; Molecular Sequence Data; Muscarinic Antagonists; Naphthalenes; Phosphatidylinositols; Piperidines; Pirenzepine; Plasmids; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Transfection | 1990 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP-Binding Proteins; In Vitro Techniques; Iris; Male; Microinjections; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Virulence Factors, Bordetella | 1995 |
Muscarinic receptors in rat uterus.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Computer Simulation; Female; Furans; In Vitro Techniques; Ligands; Muscarinic Antagonists; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Uterus | 1994 |
Enhancement of glycine release from human brain cortex synaptosomes by acetylcholine acting at M4 muscarinic receptors.
Topics: Acetylcholine; Alkaloids; Cerebral Cortex; Cholinergic Fibers; Drug Synergism; Female; Furans; Glycine; Humans; Kinetics; Male; Muscarinic Antagonists; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Potassium Chloride; Receptors, Muscarinic; Stimulation, Chemical; Synaptic Transmission; Synaptosomes; Tritium | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle.
Topics: Action Potentials; Alkaloids; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Furans; Heart Ventricles; Myocardial Contraction; Naphthalenes; Piperidines; Pirenzepine; Receptors, Muscarinic | 2007 |
Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.
Topics: Adult; Aged; Alkaloids; Animals; Cell Proliferation; Collagen; Disease Progression; Extracellular Matrix; Fibroblasts; Furans; Gene Knockdown Techniques; Humans; Mice; Mice, Knockout; Middle Aged; Myopia; Naphthalenes; Piperidines; Pirenzepine; Receptor, Muscarinic M2; RNA, Small Interfering; Sclera; Up-Regulation | 2013 |