afdx 116 has been researched along with hexahydrosiladifenidol in 31 studies
| Studies (afdx 116) | Trials (afdx 116) | Recent Studies (post-2010) (afdx 116) | Studies (hexahydrosiladifenidol) | Trials (hexahydrosiladifenidol) | Recent Studies (post-2010) (hexahydrosiladifenidol) |
|---|---|---|---|---|---|
| 367 | 1 | 24 | 65 | 0 | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (22.58) | 18.7374 |
| 1990's | 24 (77.42) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kashihara, K; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Bonner, TI; Brann, MR; Buckley, CM; Buckley, NJ | 1 |
| Ehlert, FJ; Esqueda, EE; Gerstin, EH; Griffin, MT | 1 |
| Kovacs, I; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Aguilar, JS; Ballesta, JJ; Criado, M; Palmero, M; Reig, JA; Viniegra, S | 1 |
| Bloom, JW; Halonen, M; Mahesh, VK; Nunan, LM; Palmer, JD; Yamamura, HI | 1 |
| Fernandes, LB; Fryer, AD; Hirshman, CA | 1 |
| Anderson, DJ; Connolly, T; McKinney, M; Miller, JH; Vella-Rountree, L | 1 |
| Bindslev, N; Winding, B | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E; Tacke, R | 1 |
| Birdsall, NJ; Eveleigh, P; Hulme, EC; Pedder, EK; Poyner, D | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Richards, MH | 1 |
| Baron, E; Boer, R; Eltze, M; Kromer, W | 1 |
| Elzinga, CR; Roffel, AF; Zaagsma, J | 1 |
| Hanack, C; Herawi, M; Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| Jackson, KN; Kachur, JF; Lowe, VC; Noronha-Blob, L; Sturm, BL | 1 |
| Anderson, D; el-Fakahany, EE; Forray, C; McKinney, M | 1 |
| Camus, J; Christophe, J; Waelbroeck, M; Winand, J | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E | 1 |
| Giraldo, E; Hammer, R; Ladinsky, H; Viganò, MA | 1 |
| Akiba, I; Bujo, H; Kubo, T; Maeda, A; Mishina, M; Nakai, J; Numa, S | 1 |
| Nilvebrant, L; Sparf, B | 1 |
| Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Dietrich, C; Kilbinger, H | 1 |
| Boselli, C; Grana, E | 1 |
| Robinson, NE; Wang, ZW; Yu, MF | 1 |
| Gillman, TA; Mitchelson, F; Pennefather, JN | 1 |
| Davenport, TA; Fukumoto, Y; Gousse, A; Kamai, T; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
1 review(s) available for afdx 116 and hexahydrosiladifenidol
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
30 other study(ies) available for afdx 116 and hexahydrosiladifenidol
| Article | Year |
|---|---|
Cloning of the rat M3, M4 and M5 muscarinic acetylcholine receptor genes by the polymerase chain reaction (PCR) and the pharmacological characterization of the expressed genes.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Fibroblasts; Gene Expression; Inositol Phosphates; Molecular Sequence Data; Parasympatholytics; Polymerase Chain Reaction; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Transfection | 1992 |
Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.
Topics: Animals; Cell Line; Cloning, Molecular; Cricetinae; Humans; Kinetics; N-Methylscopolamine; Parasympatholytics; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Stimulation of cyclic AMP accumulation and phosphoinositide hydrolysis by M3 muscarinic receptors in the rat peripheral lung.
Topics: Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Hydrolysis; Lung; Male; Oxotremorine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1996 |
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line.
Topics: Amino Acid Sequence; Animals; Carbachol; Cloning, Molecular; Cyclic AMP; Humans; Mice; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Muscarinic; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity | 1998 |
Muscarinic receptor subtypes in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Binding Sites; Binding, Competitive; Cattle; Cell Membrane; Dicyclomine; Muscarine; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1992 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Trachea | 1992 |
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle.
Topics: Animals; Dogs; Drug Interactions; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1992 |
Pharmacological profiles for rat cortical M1 and M2 muscarinic receptors using selective antagonists: comparison with N1E-115 muscarinic receptors.
Topics: Animals; Cerebral Cortex; Cyclic AMP; Diamines; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Phenethylamines; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bumetanide; Calcium Channels; Chickens; Chlorides; Dicyclomine; Female; In Vitro Techniques; Ion Channels; Kinetics; Mucous Membrane; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihypertensive Agents; Aorta, Abdominal; Arecoline; Atropine; Diamines; Endothelium, Vascular; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1991 |
Modulation of the structure-binding relationships of antagonists for muscarinic acetylcholine receptor subtypes.
Topics: Animals; Centrifugation; Cerebral Cortex; Cholic Acids; Digitonin; Gallamine Triethiodide; Heart; In Vitro Techniques; Lacrimal Apparatus; Membranes; Muscarinic Antagonists; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Rats; Structure-Activity Relationship | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
Telenzepine inhibits electrically-stimulated, acetylcholine plus histamine-mediated acid secretion in the mouse isolated stomach by blockade of M1 muscarine receptors.
Topics: Acetylcholine; Alkaloids; Animals; Anti-Ulcer Agents; Electric Stimulation; Furans; Gastric Acid; Gastric Mucosa; Histamine; Mice; Muscarinic Antagonists; Naphthalenes; p-Methoxy-N-methylphenethylamine; Parasympatholytics; Piperidines; Pirenzepine; Stomach; Thiazepines; Vagus Nerve | 1991 |
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle.
Topics: Bronchi; Humans; In Vitro Techniques; Ipratropium; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors.
Topics: Carbachol; Gastric Mucosa; Humans; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Piperazines; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues.
Topics: Animals; Atropine; Calcium; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Structure-Activity Relationship; Thiazepines; Tumor Cells, Cultured; Urinary Bladder; Vas Deferens | 1990 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.
Topics: Animals; Brain Stem; Corpus Striatum; Cyclic AMP; Diamines; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic | 1989 |
Different antagonist binding properties of rat pancreatic and cardiac muscarinic receptors.
Topics: Animals; Binding, Competitive; GTP-Binding Proteins; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Type C Phospholipases | 1987 |
Contribution of M2 alpha and M2 beta muscarinic receptors to the action of cholinergic stimuli on prostaglandin synthesis and mechanical function in the isolated rabbit heart.
Topics: Acetylcholine; Animals; Arecoline; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Male; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandins; Rabbits; Receptors, Muscarinic | 1988 |
Characterization of muscarinic receptors in guinea pig ileum longitudinal smooth muscle.
Topics: Animals; Binding, Competitive; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Myocardium; N-Methylscopolamine; Parasympatholytics; Phenoxybenzamine; Piperidines; Pirenzepine; Receptors, Muscarinic; Salivary Glands; Scopolamine Derivatives | 1988 |
Primary structure of porcine muscarinic acetylcholine receptor III and antagonist binding studies.
Topics: Amino Acid Sequence; Animals; Base Sequence; DNA, Recombinant; Glycosylation; Molecular Sequence Data; Muscarine; Oocytes; Piperidines; Pirenzepine; Protein Conformation; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; RNA, Messenger; Sequence Homology, Nucleic Acid; Swine; Xenopus laevis | 1988 |
Receptor binding profiles of some selective muscarinic antagonists.
Topics: Animals; Cerebral Cortex; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Parotid Gland; Piperidines; Pirenzepine; Procyclidine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Urinary Bladder | 1988 |
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1995 |
Prejunctional M1 and postjunctional M3 muscarinic receptors in the circular muscle of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Choline; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
Mode of antagonism of methoctramine, AF-DX 116 and hexahydrosiladifenidol in guinea-pig left atrium and ileum: comparison of Schild and resultant analysis.
Topics: Animals; Diamines; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine | 1995 |
Prejunctional muscarinic autoreceptors on horse airway cholinergic nerves.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Fibers; Electric Stimulation; Horses; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1995 |
Muscarinic receptors in rat uterus.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Computer Simulation; Female; Furans; In Vitro Techniques; Ligands; Muscarinic Antagonists; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Uterus | 1994 |
Diabetes-induced alterations in the properties of muscarinic cholinergic receptors in rat vas deferens.
Topics: Animals; Atropine; Binding, Competitive; Diabetes Mellitus, Experimental; Diamines; Insulin; Male; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Up-Regulation; Vas Deferens | 1994 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |