afdx 116 has been researched along with dicyclomine in 6 studies
| Studies (afdx 116) | Trials (afdx 116) | Recent Studies (post-2010) (afdx 116) | Studies (dicyclomine) | Trials (dicyclomine) | Recent Studies (post-2010) (dicyclomine) |
|---|---|---|---|---|---|
| 367 | 1 | 24 | 398 | 41 | 74 |
| Protein | Taxonomy | afdx 116 (IC50) | dicyclomine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.468 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.046 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0029 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0024 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0035 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0044 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.625 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.24 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.468 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.301 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 3.065 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.0049 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonner, TI; Brann, MR; Buckley, CM; Buckley, NJ | 1 |
| Aguilar, JS; Ballesta, JJ; Criado, M; Palmero, M; Reig, JA; Viniegra, S | 1 |
| Bindslev, N; Winding, B | 1 |
| Kunysz, EL; Michel, AD; Whiting, RL | 1 |
| Davidesko, D; de Jonge, A; Doods, HN; Mathy, MJ; van Charldorp, KJ; van Zwieten, PA | 1 |
| De Paoli, AM; Giraldo, E; Hammer, R; Martos, F; Monferini, E | 1 |
6 other study(ies) available for afdx 116 and dicyclomine
| Article | Year |
|---|---|
Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.
Topics: Animals; Cell Line; Cloning, Molecular; Cricetinae; Humans; Kinetics; N-Methylscopolamine; Parasympatholytics; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Muscarinic receptor subtypes in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Binding Sites; Binding, Competitive; Cattle; Cell Membrane; Dicyclomine; Muscarine; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1992 |
Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bumetanide; Calcium Channels; Chickens; Chlorides; Dicyclomine; Female; In Vitro Techniques; Ion Channels; Kinetics; Mucous Membrane; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Functional and direct binding studies using subtype selective muscarinic receptor antagonists.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Dicyclomine; Diphenylacetic Acids; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myocardium; Phenethylamines; Phenylacetates; Pirenzepine; Receptors, Muscarinic | 1988 |
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.
Topics: Animals; Dicyclomine; Ganglia, Sympathetic; Hippocampus; Male; Myocardium; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Submandibular Gland | 1987 |
Characterization of muscarinic receptors in salivary and lacrimal glands of the rat.
Topics: Animals; Atropine Derivatives; Dicyclomine; Exocrine Glands; In Vitro Techniques; Lacrimal Apparatus; Male; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Salivary Glands; Scopolamine Derivatives; Synaptosomes | 1987 |