afdx 116 has been researched along with bibn 99 in 3 studies
| Studies (afdx 116) | Trials (afdx 116) | Recent Studies (post-2010) (afdx 116) | Studies (bibn 99) | Trials (bibn 99) | Recent Studies (post-2010) (bibn 99) |
|---|---|---|---|---|---|
| 367 | 1 | 24 | 11 | 0 | 0 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doods, H; Eberlein, W; Engel, W; Entzeroth, M; Mihm, G; Rudolf, K; Schiavi, G; Ziegler, H | 1 |
| Bechtel, WD; Doods, HN; Engel, W; Ensinger, HA; Entzeroth, M; Ladinsky, H; Mihm, G; Quirion, R; Rudolf, K; Schiavi, GB | 1 |
| Hirano, S; Kakefuda, A; Shibata, H; Takizawa, K; Tanaka, A; Watanabe, T; Yamagiwa, Y; Yanagisawa, I | 1 |
1 review(s) available for afdx 116 and bibn 99
| Article | Year |
|---|---|
Therapeutic potential of CNS-active M2 antagonists: novel structures and pharmacology.
Topics: Animals; Benzodiazepinones; Brain; CHO Cells; Cognition Disorders; Cricetinae; Dibenzazepines; Drug Design; Motor Activity; Parasympatholytics; Piperidines; Pirenzepine; Pyridines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1993 |
2 other study(ies) available for afdx 116 and bibn 99
| Article | Year |
|---|---|
Characterization of BIBN 99: a lipophilic and selective muscarinic M2 receptor antagonist.
Topics: Animals; Binding Sites; Dibenzazepines; Guinea Pigs; Heart; Hemodynamics; Male; Muscarinic Antagonists; Muscle, Smooth; Myocardium; Parasympatholytics; Pirenzepine; Pyridines; Rabbits; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Synthesis and biological evaluation of phenylacetyl derivatives having low central nervous system permeability as potent and selective M2 muscarinic receptor antagonists.
Topics: Animals; Bradycardia; Cerebral Cortex; Dibenzazepines; Dogs; Heart; Male; Mice; Muscarinic Antagonists; Parasympatholytics; Phenylacetates; Pirenzepine; Pyridines; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivation; Structure-Activity Relationship; Submandibular Gland; Tremor | 1998 |