Compounds > afdx 116
Page last updated: 2024-09-02

afdx 116 and aceclidine

afdx 116 has been researched along with aceclidine in 4 studies

Compound Research Comparison

Studies
(afdx 116)		Trials
(afdx 116)		Recent Studies (post-2010)
(afdx 116)		Studies
(aceclidine)		Trials
(aceclidine)		Recent Studies (post-2010) (aceclidine)
3671243215

Protein Interaction Comparison

ProteinTaxonomyafdx 116 (IC50)aceclidine (IC50)
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.51
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.51
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.51
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.51
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.51

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casida, JE; Honda, H; Tomizawa, M1
Gabelt, BT; Kaufman, PL; Poyer, JF1
Gabelt, BT; Kaufman, PL1
Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S1

Other Studies

4 other study(ies) available for afdx 116 and aceclidine

ArticleYear
Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists.
    Journal of agricultural and food chemistry, 2007, Mar-21, Volume: 55, Issue:6

    Topics: Animals; Brain; Drosophila; Houseflies; Insecta; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium

2007
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
    Experimental eye research, 1994, Volume: 59, Issue:6

    Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines

1994
Inhibition of aceclidine-stimulated outflow facility, accommodation and miosis in rhesus monkeys by muscarinic receptor subtype antagonists.
    Experimental eye research, 1994, Volume: 58, Issue:5

    Topics: Accommodation, Ocular; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pupil; Quinuclidines

1994
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection

2007