af-013 has been researched along with kosinostatin* in 1 studies
1 other study(ies) available for af-013 and kosinostatin
Article | Year |
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Discovery of 16-Demethylrifamycins by Removing the Predominant Polyketide Biosynthesis Pathway in
A number of strategies have been developed to mine novel natural products based on biosynthetic gene clusters and there have been dozens of successful cases facilitated by the development of genomic sequencing. During our study on biosynthesis of the antitumor polyketide kosinostatin (KST), we found that the genome of Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Biosynthetic Pathways; Drug Discovery; Gene Deletion; Lactams, Macrocyclic; Micromonospora; Multigene Family; Polyketides; Rifamycins; Secondary Metabolism | 2019 |