af-013 and kosinostatin

af-013 has been researched along with kosinostatin* in 1 studies

Other Studies

1 other study(ies) available for af-013 and kosinostatin

ArticleYear
Discovery of 16-Demethylrifamycins by Removing the Predominant Polyketide Biosynthesis Pathway in
    Applied and environmental microbiology, 2019, 02-15, Volume: 85, Issue:4

    A number of strategies have been developed to mine novel natural products based on biosynthetic gene clusters and there have been dozens of successful cases facilitated by the development of genomic sequencing. During our study on biosynthesis of the antitumor polyketide kosinostatin (KST), we found that the genome of

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Biosynthetic Pathways; Drug Discovery; Gene Deletion; Lactams, Macrocyclic; Micromonospora; Multigene Family; Polyketides; Rifamycins; Secondary Metabolism

2019